N. Vrang, M. Tang-christensen, P. Larsen, and P. Kristensen, Recombinant CART peptide induces c-Fos expression in central areas involved in control of feeding behaviour, Brain Research, vol.818, issue.2, pp.499-509, 1999.
DOI : 10.1016/S0006-8993(98)01349-3

G. Beaudry, H. Zekki, C. Rouillard, and D. Levesque, receptor antisense reduce cocaine- and amphetamine-regulated transcript expression in the rat nucleus accumbens shell, Synapse, vol.83, issue.Suppl 7, pp.233-240, 2004.
DOI : 10.1002/syn.10302

P. Lambert, P. Couceyro, K. Mcgirr, D. Vechia, S. Smith et al., CART peptides in the central control of feeding and interactions with neuropeptide Y, Synapse, vol.35, issue.4, pp.293-298, 1998.
DOI : 10.1002/(SICI)1098-2396(199808)29:4<293::AID-SYN1>3.0.CO;2-0

J. Elmquist, C. Elias, and C. Saper, From Lesions to Leptin, Neuron, vol.22, issue.2, pp.221-232, 1999.
DOI : 10.1016/S0896-6273(00)81084-3

E. Koylu, P. Couceyro, P. Lambert, N. Ling, E. Desouza et al., Immunohistochemical Localization of Novel CART Peptides in Rat Hypothalamus, Pituitary and Adrenal Gland, Journal of Neuroendocrinology, vol.9, issue.11, pp.823-833, 1997.
DOI : 10.1046/j.1365-2826.1997.00651.x

P. Jensen, P. Kristensen, J. Clausen, M. Judge, S. Hastrup et al., The hypothalamic satiety peptide CART is expressed in anorectic and non-anorectic pancreatic islet tumors and in the normal islet of Langerhans, FEBS Letters, vol.169, issue.2-3, pp.2-3139, 1999.
DOI : 10.1016/S0014-5793(99)00291-4

C. Broberger, K. Holmberg, M. Kuhar, and T. Hokfelt, Cocaine- and amphetamine-regulated transcript in the rat vagus nerve: A putative mediator of cholecystokinin-induced satiety, Proceedings of the National Academy of Sciences, vol.94, issue.2, pp.9613506-13511, 1999.
DOI : 10.1016/0012-1606(82)90349-9

P. Kristensen, M. Judge, L. Thim, U. Ribel, K. Christjansen et al., Hypothalamic CART is a new anorectic peptide regulated by leptin, Nature, issue.6680, pp.39372-76, 1998.

K. Wortley, G. Chang, Z. Davydova, S. Fried, and S. Leibowitz, Cocaine- and amphetamine-regulated transcript in the arcuate nucleus stimulates lipid metabolism to control body fat accrual on a high-fat diet, Regulatory Peptides, vol.117, issue.2, pp.89-99, 2004.
DOI : 10.1016/j.regpep.2003.08.005

M. Asnicar, D. Smith, D. Yang, M. Heiman, N. Fox et al., Absence of Cocaine- and Amphetamine-Regulated Transcript Results in Obesity in Mice Fed a High Caloric Diet, Endocrinology, vol.142, issue.10, pp.1424394-4400, 2001.
DOI : 10.1210/endo.142.10.8416

S. Echwald, T. Sorensen, T. Andersen, C. Hansen, N. Tommerup et al., Sequence Variants in the Human Cocaine and Amphetamine-Regulated Transcript (CART) Gene in Subjects with Early Onset Obesity, Obesity Research, vol.18, issue.6, pp.532-536, 1999.
DOI : 10.1002/j.1550-8528.1999.tb00710.x

B. Challis, G. Yeo, I. Farooqi, J. Luan, S. Aminian et al., Rahilly S: The CART gene and human obesity: mutational analysis and population genetics, Diabetes, issue.5, pp.49872-875, 2000.

K. Walder, C. Morris, and E. Ravussin, A polymorphism in the gene encoding CART is not associated with obesity in Pima Indians, International Journal of Obesity, vol.24, issue.4, pp.520-521, 2000.
DOI : 10.1038/sj.ijo.0801196

K. Yamada, X. Yuan, S. Otabe, A. Koyanagi, W. Koyama et al., Sequencing of the putative promoter region of the cocaine- and amphetamine-regulated-transcript gene and identification of polymorphic sites associated with obesity, International Journal of Obesity, vol.26, issue.1, pp.132-136, 2002.
DOI : 10.1038/sj.ijo.0801848

J. Hager, C. Dina, S. Francke, S. Dubois, M. Houari et al., A genome-wide scan for human obesity genes reveals a major susceptibility locus on chromosome 10, Nat Genet, vol.20, issue.3, pp.304-308, 1998.

D. Crawford, C. Carlson, M. Rieder, D. Carrington, Q. Yi et al., Haplotype Diversity across 100 Candidate Genes for Inflammation, Lipid Metabolism, and Blood Pressure Regulation in Two Populations, The American Journal of Human Genetics, vol.74, issue.4, pp.610-622, 2004.
DOI : 10.1086/382227

S. Slager and D. Schaid, Case-Control Studies of Genetic Markers: Power and Sample Size Approximations for Armitage???s Test for Trend, Human Heredity, vol.52, issue.3, pp.149-153, 2001.
DOI : 10.1159/000053370

D. Tregouet, S. Barbaux, S. Escolano, N. Tahri, J. Golmard et al., Specific haplotypes of the P-selectin gene are associated with myocardial infarction, Human Molecular Genetics, vol.11, issue.17, pp.112015-2023, 2002.
DOI : 10.1093/hmg/11.17.2015

S. Oyadomari and M. Mori, Roles of CHOP/GADD153 in endoplasmic reticulum stress, Cell Death and Differentiation, vol.11, issue.4, pp.381-389, 2004.
DOI : 10.1038/sj.cdd.4401373

G. Dominguez, A. Lakatos, and M. Kuhar, Characterization of the cocaine- and amphetamine-regulated transcript (CART) peptide gene promoter and its activation by a cyclic AMP-dependent signaling pathway in GH3 cells, Journal of Neurochemistry, vol.80, issue.5, pp.885-893, 2002.
DOI : 10.1046/j.0022-3042.2002.00775.x

M. Fu, H. Cheng, L. Chen, B. Wu, M. Cai et al., [Association of the cocaine and amphetamine-regulated transcript gene with type 2 diabetes mellitus, Zhonghua Nei Ke Za Zhi, issue.12, pp.41805-808, 2002.

F. Vasseur, N. Helbecque, C. Dina, S. Lobbens, V. Delannoy et al., Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians, Human Molecular Genetics, vol.11, issue.21, pp.112607-2614, 2002.
DOI : 10.1093/hmg/11.21.2607

URL : https://hal.archives-ouvertes.fr/hal-00174613

C. Lewis, Genetic association studies: Design, analysis and interpretation, Briefings in Bioinformatics, vol.3, issue.2, pp.146-153, 2002.
DOI : 10.1093/bib/3.2.146

D. Hartl and A. Clark, Principles of Population Genetics Sinauer Associates, pp.111-162

S. Otabe, K. Clement, C. Dina, V. Pelloux, B. Guy-grand et al., A genetic variation in the 5 ??? flanking region of the UCP3 gene is associated with body mass index in humans in interaction with physical activity, Diabetologia, vol.43, issue.2, pp.245-249, 2000.
DOI : 10.1007/s001250050037

URL : https://hal.archives-ouvertes.fr/hal-00174919

P. Boutin, C. Dina, F. Vasseur, S. Dubois, L. Corset et al., GAD2 on Chromosome 10p12 Is a Candidate Gene for Human Obesity, PLoS Biology, vol.50, issue.3, pp.2-68, 2003.
DOI : 10.1371/journal.pbio.0000068.t003

URL : https://hal.archives-ouvertes.fr/hal-00174549

D. Nielsen, M. Ehm, and B. Weir, Detecting Marker-Disease Association by Testing for Hardy-Weinberg Disequilibrium at a Marker Locus, The American Journal of Human Genetics, vol.63, issue.5, pp.1531-1540, 1998.
DOI : 10.1086/302114

N. Morton and A. Collins, Tests and estimates of allelic association in complex inheritance, Proceedings of the National Academy of Sciences, vol.57, issue.2, pp.9511389-11393, 1998.
DOI : 10.1073/pnas.89.7.2556

R. Branson, N. Potoczna, J. Kral, K. Lentes, M. Hoehe et al., Binge Eating as a Major Phenotype of Melanocortin 4 Receptor Gene Mutations, New England Journal of Medicine, vol.348, issue.12, pp.1096-1103, 2003.
DOI : 10.1056/NEJMoa021971

S. Hercberg, P. Preziosi, S. Briancon, P. Galan, I. Triol et al., A Primary Prevention Trial Using Nutritional Doses of Antioxidant Vitamins and Minerals in Cardiovascular Diseases and Cancers in a General Population, Controlled Clinical Trials, vol.19, issue.4, pp.336-351, 1998.
DOI : 10.1016/S0197-2456(98)00015-4

F. Lepretre, C. Cheyssac, P. Amouyel, P. Froguel, and N. Helbecque, A promoter polymorphism in CD36 is associated with an atherogenic lipid profile in a French general population, Atherosclerosis, vol.173, issue.2, pp.375-377, 2004.
DOI : 10.1016/j.atherosclerosis.2003.12.029

URL : https://hal.archives-ouvertes.fr/hal-00094109

P. Boutin, C. Wahl, C. Samson, F. Vasseur, F. Laget et al., Big Dye? terminator cycle sequencing chemistry: Accuracy of the dilution process and application for screening mutations in the TCF1 and GCK genes, Human Mutation, vol.25, issue.2, pp.201-203, 2000.
DOI : 10.1002/(SICI)1098-1004(200002)15:2<201::AID-HUMU11>3.0.CO;2-8

B. Blomeke, S. Sieben, D. Spotter, O. Landt, and H. Merk, Identification of N-Acetyltransferase 2 Genotypes by Continuous Monitoring of Fluorogenic Hybridization Probes, Analytical Biochemistry, vol.275, issue.1, pp.93-97, 1999.
DOI : 10.1006/abio.1999.4288

F. Dudbridge, Pedigree disequilibrium tests for multilocus haplotypes, Genetic Epidemiology, vol.50, issue.2, pp.115-121, 2003.
DOI : 10.1002/gepi.10252

URL : http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.471.9897

X. Wang, M. Kuroda, J. Sok, N. Batchvarova, R. Kimmel et al., Identification of novel stress-induced genes downstream of chop, The EMBO Journal, vol.17, issue.13, pp.173619-3630, 1998.
DOI : 10.1093/emboj/17.13.3619

E. Schreiber, M. P. Muller, M. Schaffner, and W. , Rapid detection of octamer binding proteins with ???mini extracts???, prepared from a small number of cells, Nucleic Acids Research, vol.17, issue.15, p.176419, 1989.
DOI : 10.1093/nar/17.15.6419