V. Nell, K. Machold, G. Eberl, T. Stamm, M. Uffmann et al., Benefit of very early referral and very early therapy with disease-modifying anti-rheumatic drugs in patients with early rheumatoid arthritis, Rheumatology, vol.43, issue.7, pp.906-914, 2004.
DOI : 10.1093/rheumatology/keh199

F. Arnett, S. Edworthy, D. Bloch, D. Mcshane, J. Fries et al., The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis, Arthritis & Rheumatism, vol.143, issue.3, pp.315-324, 1988.
DOI : 10.1002/art.1780310302

M. Van-boekel, E. Vossenaar, F. Van-den-hoogen, and W. Van-venrooij, Autoantibody systems in rheumatoid arthritis: specificity, sensitivity and diagnostic value, Arthritis Research, vol.4, issue.2, pp.87-93, 2002.
DOI : 10.1186/ar395

M. Nielen, D. Van-schaardenburg, H. Reesink, R. Van-de-stadt, I. Van-der-horst-bruinsma et al., Specific autoantibodies precede the symptoms of rheumatoid arthritis: A study of serial measurements in blood donors, Arthritis & Rheumatism, vol.44, issue.2, pp.380-386, 2004.
DOI : 10.1002/art.20018

O. Vittecoq, B. Incaurgarat, F. Jouen-beades, J. Legoedec, O. Letourneur et al., Autoantibodies recognizing citrullinated rat filaggrin in an ELISA using citrullinated and non-citrullinated recombinant proteins as antigens are highly diagnostic for rheumatoid arthritis, Clinical and Experimental Immunology, vol.62, issue.1, pp.173-180, 2004.
DOI : 10.1002/art.10229

A. Jansen, I. Van-der-horst-bruinsma, D. Van-schaardenburg, R. Van-de-stadt, M. De-koning et al., Rheumatoid factor and antibodies to cyclic citrullinated Peptide differentiate rheumatoid arthritis from undifferentiated polyarthritis in patients with early arthritis, J Rheumatol, vol.29, pp.2074-2076, 2002.

P. Gregersen, J. Silver, and R. Winchester, The shared epitope hypothesis. an approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis, Arthritis & Rheumatism, vol.4, issue.11, pp.1205-1213, 1987.
DOI : 10.1002/art.1780301102

W. Thomson, B. Harrison, B. Ollier, N. Wiles, T. Payton et al., Quantifying the exact role of HLA-DRB1 alleles in susceptibility to inflammatory polyarthritis: Results from a large, population-based study, Arthritis & Rheumatism, vol.39, issue.4, pp.757-762, 1999.
DOI : 10.1002/1529-0131(199904)42:4<757::AID-ANR20>3.0.CO;2-X

M. Seldin, C. Amos, R. Ward, and P. Gregersen, The genetics revolution and the assault on rheumatoid arthritis, Arthritis & Rheumatism, vol.18, issue.Suppl 9, pp.1071-1079, 1999.
DOI : 10.1002/1529-0131(199906)42:6<1071::AID-ANR1>3.0.CO;2-8

F. Cornelis, S. Faure, M. Martinez, J. Prud-'homme, P. Fritz et al., New susceptibility locus for rheumatoid arthritis suggested by a genome-wide linkage study, Proceedings of the National Academy of Sciences, vol.6, issue.7, pp.10746-10750, 1998.
DOI : 10.1093/hmg/6.7.1003

S. Shiozawa, S. Hayashi, Y. Tsukamoto, H. Goko, H. Kawasaki et al., Identification of the gene loci that predispose to rheumatoid arthritis., International Immunology, vol.10, issue.12, pp.1891-1895, 1998.
DOI : 10.1093/intimm/10.12.1891

O. Kemper, J. Derre, D. Cherif, H. Engelmann, D. Wallach et al., The gene for the type II (p75) tumor necrosis factor receptor (TNF-RII) is localized on band 1p36.2?p36.3, Human Genetics, vol.87, issue.5, pp.623-624, 1991.
DOI : 10.1007/BF00209026

A. Barton, S. John, W. Ollier, A. Silman, and J. Worthington, Association between rheumatoid arthritis and polymorphism of tumor necrosis factor receptor II, but not tumor necrosis factor receptor I, in Caucasians, Arthritis & Rheumatism, vol.43, issue.1, pp.61-65, 2001.
DOI : 10.1002/1529-0131(200101)44:1<61::AID-ANR9>3.0.CO;2-Q

P. Dieude, E. Petit, S. Cailleau-moindrault, J. Osorio, C. Pierlot et al., Association between tumor necrosis factor receptor II and familial, but not sporadic, rheumatoid arthritis: Evidence for genetic heterogeneity, Arthritis & Rheumatism, vol.43, issue.Suppl 9, pp.2039-2044, 2002.
DOI : 10.1002/art.10101

C. Kyogoku, N. Tsuchiya, T. Shibue, K. Tokunaga, and K. Matsuta, TNFR2 position 196 polymorphism in Japanese patients with rheumatoid arthritis: Comment on the article by Dieud?? et al, Arthritis & Rheumatism, vol.48, issue.1, pp.273-274, 2003.
DOI : 10.1002/art.10600

S. Dahlqvist, L. Arlestig, C. Sikstrom, and S. Linghult, Tumor necrosis factor receptor type II (exon 6) and interleukin-6 (???174) gene polymorphisms are not associated with family history but tumor necrosis factor receptor type II is associated with hypertension in patients with rheumatoid arthritis from northe, Arthritis & Rheumatism, vol.26, issue.Suppl 9, pp.3096-3098, 2002.
DOI : 10.1002/art.10592

A. Constantin, P. Dieude, V. Lauwers-cances, B. Jamard, B. Mazieres et al., Tumor necrosis factor receptor II gene polymorphism and severity of rheumatoid arthritis, Arthritis & Rheumatism, vol.39, issue.3, pp.742-747, 2004.
DOI : 10.1002/art.20113

J. Glossop, N. Nixon, P. Dawes, A. Hassell, and D. Mattey, No association of polymorphisms in the tumor necrosis factor receptor I and receptor II genes with disease severity in rheumatoid arthritis, J Rheumatol, vol.30, pp.1406-1409, 2003.

A. Van-der-helm-van-mil, P. Dieude, J. Schonkeren, F. Cornelis, and T. Huizinga, No association between tumour necrosis factor receptor type 2 gene polymorphism and rheumatoid arthritis severity: a comparison of the extremes of phenotypes, Rheumatology, vol.43, issue.10, pp.1232-1234, 2004.
DOI : 10.1093/rheumatology/keh314

D. Van-der-heijde, M. Van-'t-hof, P. Van-riel, L. Theunisse, E. Lubberts et al., Judging disease activity in clinical practice in rheumatoid arthritis: first step in the development of a disease activity score., Annals of the Rheumatic Diseases, vol.49, issue.11, pp.916-920, 1990.
DOI : 10.1136/ard.49.11.916

C. Morita, T. Horiuchi, H. Tsukamoto, N. Hatta, Y. Kikuchi et al., Association of tumor necrosis factor receptor type II polymorphism 196R with systemic lupus erythematosus in the Japanese: Molecular and functional analysis, Arthritis & Rheumatism, vol.334, issue.12, pp.2819-2827, 2001.
DOI : 10.1002/1529-0131(200112)44:12<2819::AID-ART469>3.0.CO;2-2

E. Berglin, L. Padyukov, U. Sundin, G. Hallmans, H. Stenlund et al., A combination of autoantibodies to cyclic citrullinated peptide (CCP) and HLA- DRB1 locus antigens is strongly associated with future onset of rheumatoid arthritis, Arthritis Research & Therapy, vol.6, issue.4, pp.303-308, 2004.
DOI : 10.1186/ar1187

J. Van-aken, L. Lard, S. Le-cessie, J. Hazes, F. Breedveld et al., Radiological outcome after four years of early versus delayed treatment strategy in patients with recent onset rheumatoid arthritis, Annals of the Rheumatic Diseases, vol.63, issue.3, pp.274-279, 2004.
DOI : 10.1136/ard.2003.010298

L. Lard, M. Boers, A. Verhoeven, K. Vos, H. Visser et al., Early and aggressive treatment of rheumatoid arthritis patients affects the association of HLA class II antigens with progression of joint damage, Arthritis & Rheumatism, vol.46, issue.4, pp.899-905, 2002.
DOI : 10.1002/art.10151

N. Nishimoto, K. Yoshizaki, N. Miyasaka, K. Yamamoto, S. Kawai et al., Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: A multicenter, double-blind, placebo-controlled trial, Arthritis & Rheumatism, vol.39, issue.6, pp.1761-1769, 2004.
DOI : 10.1002/art.20303

A. Till, P. Rosenstiel, A. Krippner-heidenreich, S. Mascheretti-croucher, P. Croucher et al., The Met-196 -> Arg Variation of Human Tumor Necrosis Factor Receptor 2 (TNFR2) Affects TNF-??-induced Apoptosis by Impaired NF-??B Signaling and Target Gene Expression, Journal of Biological Chemistry, vol.280, issue.7, pp.5994-6004, 2005.
DOI : 10.1074/jbc.M411541200

M. Fabris, B. Tolusso, D. Poi, E. Assaloni, R. Sinigaglia et al., Tumor necrosis factor-alpha receptor II polymorphism in patients from southern Europe with mild-moderate and severe rheumatoid arthritis, J Rheumatol, vol.29, pp.1847-1850, 2002.