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[Breakthroughs in the study of the influence of environmental factors on male reproductive health]

Abstract : BACKGROUND: An important part of the research effort on male reproductive health focus on two important questions: on the one side, that of the temporal deterioration of male reproductive health and, on the other head, that of the influence of exposure to environmental chemicals during intra-uterine life on health during childhood and adulthood. The concepts on endocrine disruption and testicular dysgenesis syndrome make a link between these two questions. METHODS: This work examines knowledge cumulated over the last couple of years concerning geographical and temporal variations in male reproductive health and the testicular dysgenesis syndrome. Recent results concerning the concept of endocrine disruption and on the environmental influences on male reproduction are presented, as well as on the transgenerational effects on environmental factors on the health of male children. CONCLUSIONS: Based on clinical and epidemiological data, and with the use of in vitro animal models as well as observations in wildlife, research in this field has enabled progress in the elucidation of mechanisms of action and characterization of environmental influences on male reproductive health.
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https://www.hal.inserm.fr/inserm-00087541
Contributor : Nadine Kaniewski <>
Submitted on : Tuesday, July 25, 2006 - 11:19:33 AM
Last modification on : Wednesday, September 16, 2020 - 4:57:34 PM

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  • HAL Id : inserm-00087541, version 1
  • PUBMED : 16830971

Citation

Rémy Slama, Bernard Jégou, Sylvaine Cordier. [Breakthroughs in the study of the influence of environmental factors on male reproductive health]. Epidemiology and Public Health / Revue d'Epidémiologie et de Santé Publique, Elsevier Masson, 2006, 54, pp.167-74. ⟨inserm-00087541⟩

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