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Table 2.

TDT of the RELN gene 5′UTR (GGC)n variant in autistic disorder

Alleles Trios
Sib pairs
Total sample
χ2 P
T NT T NT T NT
4 2 0 0 0 2 0
5 1 0 0 0 1 0
7 1 0 0 0 1 0
8 54 67 49 49 103 116 0.77 0.38
10 63 58 47 45 110 103 0.23 0.63
11 2 1 2 0 4 1
12 1 3 1 1 2 4
13 11 7 4 6 15 13 0.14 0.71
14 1 0 0 2 1 2
16 0 0 1 1 1 1

T = transmitted, NT = not transmitted. Total sample; allele-wise TDT, c2 = 8.99, df =9, p= 0.44; genotype-wise TDT, c2 = 20.15, df = 14, p = 0.13. In the last two columns are indicated the c2 and p values for the transmission of individual alleles in the total sample.

Mol Psychiatry. 2002; 7(7): 801–4.
doi: 10.1038/sj.mp.4001071.