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Article Dans Une Revue ChemCatChem Année : 2013

Nickel-Catalyzed Reductive Amination with Hydrosilanes.

Résumé

The authors have developed a nickel-catalyzed reductive amination of aldehydes using an in-situ-generated catalyst from nickel(II) acetate and tricyclohexylphosphine. The synthesis of the target compds. was achieved using tetramethyldisiloxane as a hydrosilane reagent. Secondary amines were formed in moderate-to-good product yields. The title compds. thus formed included 4-[[(4-methoxyphenyl)amino]methyl]phenol, N-(4-fluorophenyl)benzenemethanamine, N-[4-[[(4-methoxyphenyl)amino]methyl]phenyl]acetamide, N-(dodecyl)benzenemethanamine, N-(dodecyl)benzeneethanamine, N-octyl-1-dodecanamine, 4-[[(4-methoxyphenyl)amino]methyl]benzonitrile. [on SciFinder(R)]

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Autre

Dates et versions

hal-01069941 , version 1 (30-09-2014)

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Jianxia Zheng, Thierry Roisnel, Christophe Darcel, Jean-Baptiste Sortais. Nickel-Catalyzed Reductive Amination with Hydrosilanes.. ChemCatChem, 2013, 5, pp.2861--2864. ⟨10.1002/cctc.201300338⟩. ⟨hal-01069941⟩
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