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An In-House Assay Is Superior to Sepsityper for Direct Matrix-Assisted Laser Desorption Ionization-Time of Flight (MALDI-TOF) Mass Spectrometry Identification of Yeast Species in Blood Cultures

Abstract : We developed an in-house assay for the direct identification, by matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry, of yeasts in blood culture. Sixty-one representative strains from 12 species were analyzed in spiked blood cultures. Our assay accurately identified 95 of 107 (88.8%) positive blood cultures and outperformed the commercial Sepsityper kit (81.7% identification).
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https://hal.archives-ouvertes.fr/hal-03034336
Contributor : Aurélie Hennebique <>
Submitted on : Friday, January 22, 2021 - 1:52:42 PM
Last modification on : Monday, January 25, 2021 - 4:14:12 PM

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Marie Bidart, Isabelle Bonnet, Aurélie Hennebique, Zine Eddine Kherraf, Hervé Pelloux, et al.. An In-House Assay Is Superior to Sepsityper for Direct Matrix-Assisted Laser Desorption Ionization-Time of Flight (MALDI-TOF) Mass Spectrometry Identification of Yeast Species in Blood Cultures. Journal of Clinical Microbiology, American Society for Microbiology, 2015, 53 (5), pp.1761-1764. ⟨10.1128/JCM.03600-14⟩. ⟨hal-03034336⟩

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