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Intravenous Mineralocorticoid Receptor Antagonist Use in Acutely Decompensated Heart Failure with Diuretic Resistance

Abstract : Intravenous mineralocorticoid receptor antagonists (MRAs) have been used in some centers for decades to reduce the risk of hypokalemia and boost diuresis in acutely decompensated heart failure (ADHF). We report the well-tolerated use of intravenous MRAs as a rescue procedure in 3 patients admitted for ADHF with important diuretic resistance. Undertaking trials evaluating the effect of this therapeutic strategy in ADHF could represent a promising avenue.
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https://hal.univ-lorraine.fr/hal-03116131
Contributor : Erwan Bozec <>
Submitted on : Wednesday, January 20, 2021 - 10:02:44 AM
Last modification on : Tuesday, March 23, 2021 - 12:14:06 PM

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Nicolas Girerd, Matthieu Aubry, Pierre Lantelme, Olivier Huttin, Patrick Rossignol. Intravenous Mineralocorticoid Receptor Antagonist Use in Acutely Decompensated Heart Failure with Diuretic Resistance. International Heart Journal, International Heart Journal Association, 2021, 62 (1), pp.193-196. ⟨10.1536/ihj.20-442⟩. ⟨hal-03116131⟩

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