PMID: identifiant
de la référence Pubmed : |
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 (10026722) |
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| titre : |
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[Management of DNA banks: ethical concerns] |
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| auteur(s) : |
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Grégoire Moutel1, Sandrine De Montgolfier1, Karine Corviole2, Martine Gaillard1, Vincent Durlach, Marc Leutenegger3, Jean-Jacques Adnet4, Christian Hervé1 |
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| laboratoire : |
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| résumé : |
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With the creation of DNA banks, short and long-term studies can be conducted on the DNA of many individuals using stored cells and tissues. These studies allow an analysis of the pathophysiological impact of genetics and help define individual markers predictive of risk. Genome analysis is thus an important advance in medical science, providing essential information for establishing appropriate measures to slow disease development, limit severity or improve safe recovery. The use of genetic results may however have an adverse effect in certain situations if the genetic information collected were deviated from its purely medical purpose under the influence of social, occupational or economic factors. The aim of our study was to analyse the ethical challenges linked to the implementation of DNA banks in France, particularly to see how to maintain the concept of individual protection in biomedical research within the patient-physician relationship in the current context of legal and administrative regulations in France. In this study, we discuss a set of criteria which should be systematically evaluated in information collection and consent procedures prior to blood or tissue procurement for DNA bank purposes. |
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| domaine : |
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Sciences du Vivant/Ethique
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langue du texte
intégral : |
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Français |
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| ISSN : |
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0755-4982 |
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| type de publication : |
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Articles dans des revues avec comité de lecture |
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| journal : |
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Presse médicale (Paris, France : 1983) |
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| Audience : |
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non spécifiée |
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| date de publication : |
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23/01/1999 |
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| volume : |
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28 |
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| numéro : |
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3 |
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| page, identifiant, ... : |
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135-9 |
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| mots-clés auteur : |
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Biothèques – Banques d'ADN – Ethique – Information – Relation médecin-malade – Evaluation – Biobanks – DNA banking – Ethical concerns – Patient relationship |
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| Descripteur(s) MeSH : |
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Biological Specimen Banks – DNA – English Abstract – Ethics – Medical – Gene Library – Humans – Physician-Patient Relations – Tissue and Organ Procurement |
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