PMID: identifiant
de la référence Pubmed : |
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 (19246716)  |
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| titre : |
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Prospective study of physical activity and risk of asthma exacerbations in older women. |
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| auteur(s) : |
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Judith Garcia-Aymerich ( ) 1, 2, 3, 4, Raphaëlle Varraso1, 5, 6, Josep Antó1, 2, 3, 4, Carlos Camargo6, 7 |
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| laboratoire : |
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| 1 : |
CREAL - Center for Research in Environmental Epidemiology |
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| Universitat Pompeu Fabra – Catalunya ministerio de salud |
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| Doctor Aiguader, 88 E-08003 Barcelona |
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| Espagne |
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| 2 : |
IMIM-Hospital del Mar |
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| http://www.imim.es/en_index.html |
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| Generalitat de Catalunya |
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| Parc de Recerca Biomèdica de Barcelona C/ Doctor Aiguader, 88 08003 Barcelona |
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| Espagne |
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| 3 : |
Department of Experimental and Health Sciences |
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| Universitat Pompeu Fabra |
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| Doctor Aiguader 88, 08003 Barcelona |
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| Espagne |
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| 4 : |
CIBERESP - CIBER Epidemiologia y Salud Pública |
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| CIBER Epidemiologia y Salud Pública |
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| Doctor Aiguader 88, 08003 Barcelona |
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| Espagne |
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| 5 : |
Recherche en épidémiologie et biostatistique |
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| INSERM : IFR69 – Université Paris XI - Paris Sud |
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| 16, Avenue Paul Vaillant-Couturier 94807 VILLEJUIF CEDEX |
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| France |
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| 6 : |
Department of Emergency Medicine |
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| Massachusetts General Hospital, Harvard Medical School |
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| Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA |
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| France |
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| 7 : |
Channing Laboratory, Department of Medicine, Brigham & Women's Hospital |
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| Brigham and Women's Hospital - Harvard Medical School |
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| Harvard Medical School, Boston, MA, USA |
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| États-Unis |
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| titre abrégé : |
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Physical activity and asthma exacerbations |
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| résumé : |
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RATIONALE: The potential role of physical activity in preventing asthma exacerbations is unknown. OBJECTIVES: To investigate the longitudinal association between regular physical activity and asthma exacerbations. METHODS: A total of 2,818 women with asthma from a large U.S. cohort (the Nurses' Health Study) were monitored from 1998 to 2000. Physical activity was self-reported at baseline, using a validated questionnaire, and categorized in quintiles. Exacerbations during follow-up were defined as a self-report of asthma-related hospitalization, emergency department visit, or urgent office visit. Baseline information about severity of asthma, treatment, previous exacerbations, sociodemographic factors, smoking, and other potential confounders was obtained. MEASUREMENTS AND MAIN RESULTS: Participants had a mean age of 63 years, and 71% had mild-to-moderate persistent asthma. About half of the women were ever-smokers (48% former, 6% current), and median physical activity was 10 MET x hours/week (equivalent to walking at a brisk pace for 20 minutes three times per week). Risk of exacerbations during follow-up decreased with increasing level of physical activity. In a multivariate logistic regression model, the higher level of physical activity, the lower risk of admission (odds ratio 0.85, 0.81, 0.78, and 0.76, for the 2nd, 3rd, 4th, and 5th quintiles compared with the 1st quintile, P for trend = 0.05). There were no relevant differences on stratifying by age group, smoking status, body mass index, baseline use of inhaled corticosteroids, or previous exacerbations. CONCLUSIONS: Regular physical activity was associated with reduced risk of exacerbations in women with asthma in this longitudinal study. |
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| domaine : |
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Sciences du Vivant/Santé publique et épidémiologie
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langue du texte
intégral : |
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Anglais |
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| ISSN : |
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1073-449X |
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| type de publication : |
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Articles dans des revues avec comité de lecture |
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| DOI : |
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10.1164/rccm.200812-1929OC |
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| journal : |
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| American Journal of Respiratory and Critical Care Medicine (Am J Respir Crit Care Med) |
| Publisher |
American Thoracic Society |
| ISSN |
1073-449X (eISSN : 1535-4970) |
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| Audience : |
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internationale |
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| date de publication : |
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01/06/2009 |
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date de publication
électronique : |
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26/02/2009 |
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| volume : |
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179 |
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| numéro : |
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11 |
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| page, identifiant, ... : |
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999-1003 |
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| mots-clés auteur : |
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Motor activity – Exercise – Asthma – Epidemiology |
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| Descripteur(s) MeSH : |
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Aged – Asthma – Female – Health Surveys – Humans – Middle Aged – Motor Activity – Odds Ratio – Prospective Studies |
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