PMID: identifiant de la référence Pubmed : |
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(20172921)  |
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| titre : |
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Prospective study of dietary fiber and risk of chronic obstructive pulmonary disease among US women and men. |
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| auteur(s) : |
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Raphaëlle Varraso ( ) 1, Walter Willett2, 3, 4, Carlos Camargo3, 4, 5 |
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| laboratoire : |
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| 1 : |
Recherche en épidémiologie et biostatistique |
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| INSERM : IFR69 – Université Paris XI - Paris Sud |
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| 16, Avenue Paul Vaillant-Couturier 94807 VILLEJUIF CEDEX |
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| France |
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| 2 : |
Department of Nutrition |
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| Harvard School of Public Health |
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| Boston, MA |
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| États-Unis |
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| 3 : |
Channing Laboratory, Department of Medicine, Brigham & Women's Hospital |
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| Brigham and Women's Hospital - Harvard Medical School |
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| Harvard Medical School, Boston, MA, USA |
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| États-Unis |
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| 4 : |
Department of Epidemiology |
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| Harvard School of Public Health |
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| Harvard School of Public Health, Boston, MA, USA |
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| États-Unis |
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| 5 : |
Department of Emergency Medicine |
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| Massachusetts General Hospital, Harvard Medical School |
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| Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA |
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| France |
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| titre abrégé : |
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Fiber intake and risk of COPD |
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| résumé : |
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Little is known about the relation between dietary fiber intake and the incidence of respiratory diseases, especially chronic obstructive pulmonary disease (COPD). The authors investigated this issue among 111,580 US women and men (Nurses' Health Study and Health Professionals Follow-up Study), with 832 cases of newly diagnosed COPD being reported between 1984 and 2000. The cumulative average intake of total fiber and of fiber from specific sources (cereal, fruit, and vegetables) was calculated from food frequency questionnaires and a food composition database and divided into quintiles. After adjustment for 11 factors (age, sex, smoking, energy intake, body mass index, US region, physician visits, physical activity, diabetes, and intakes of omega-3 and cured meat), total dietary fiber intake was negatively associated with risk of newly diagnosed COPD (for highest vs. lowest intake, relative risk = 0.67, 95% confidence interval: 0.50, 0.90; P(trend) = 0.03). For specific fiber sources (cereal, fruit, and vegetables), only cereal fiber was significantly associated with newly diagnosed COPD independently of other fiber sources (for highest vs. lowest intake, relative risk = 0.77, 95% confidence interval: 0.59, 0.99; P(trend) = 0.04). These data suggest that a diet high in fiber, and possibly specifically cereal fiber, may reduce risk of developing COPD. |
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| domaine : |
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Sciences du Vivant/Santé publique et épidémiologie
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langue du texte intégral : |
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Anglais |
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| ISSN : |
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0002-9262 |
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| type de publication : |
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Articles dans des revues avec comité de lecture |
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| DOI : |
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10.1093/aje/kwp455 |
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| journal : |
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| Audience : |
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internationale |
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| date de publication : |
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01/04/2010 |
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date de publication électronique : |
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19/02/2010 |
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| volume : |
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171 |
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| numéro : |
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7 |
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| page, identifiant, ... : |
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776-84 |
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| mots-clés auteur : |
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diet – fiber – chronic obstructive pulmonary diseases – sex |
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| Descripteur(s) MeSH : |
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Adult – Aged – Cereals – Dietary Fiber – Female – Food Habits – Fruit – Humans – Incidence – Lung Diseases – Male – Middle Aged – Multivariate Analysis – Proportional Hazards Models – Prospective Studies – Pulmonary Disease – Chronic Obstructive – Sex Distribution – United States – Vegetables – Adult |
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| contrat, financement : |
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Supported by research grants CA-87969, HL-63841, HL-60712, HL-77612, AI- 52338 and CA-55075 from the National Institutes of Health (Bethesda, Maryland). |
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