Occupation and lymphoid malignancies: results from a French case-control study.

Laurent L. Orsi; Xavier X. Troussard; Alain A. Monnereau; Christian C. Berthou; Pierre P. Fenaux; Gerald G. Marit; Pierre P. Soubeyran; Françoise F. Huguet; Noel Milpied; Michel M. Leporrier; Denis Hemon; Jacqueline Clavel

inserm-00239464, version 1

Occupation and lymphoid malignancies: results from a French case-control study.
Orsi L. L., Troussard X. X., Monnereau A. A., Berthou C. C., Fenaux P. P., Marit G. G., Soubeyran P. P., Huguet F. F., Milpied N., Leporrier M. M. et al
Journal of Occupational & Environmental Medicine 49, 12 (2007) 1339-50 - http://www.hal.inserm.fr/inserm-00239464

PMID: identifiant
de la référence Pubmed :

(18231081)

titre :

Occupation and lymphoid malignancies: results from a French case-control study.

auteur(s) :

Laurent Orsi (

) ¹, Xavier Troussard², Alain Monnereau^{1, 3}, Christian Berthou⁴, Pierre Fenaux⁵, Gerald Marit⁶, Pierre Soubeyran³, Françoise Huguet⁷, Noel Milpied⁸, Michel Leporrier², Denis Hemon¹, Jacqueline Clavel¹

laboratoire :

1 :	Epidémiologie environnementale des cancers

http://ifr69.vjf.inserm.fr/u754/

INSERM : IFR69 – Université Paris XI - Paris Sud

16, Avenue Paul Vaillant-Couturier 94807 VILLEJUIF CEDEX

France

2 :	Service d'Hématologie

CHU Caen – Hôpital côte de nacre

14000 Caen

France

3 :	Institut Bergonié

http://www.bergonie.org/

Institut Bergonié - CRLCC Bordeaux

33076 Bordeaux Cedex

France

4 :	Hôpital Morvan

CHU Brest

Brest

France

5 :	Service d'hématologie clinique [Avicenne]

Assistance publique - Hôpitaux de Paris (AP-HP) – Hôpital Avicenne – Université Paris XIII - Paris Nord

125, rue de Stalingrad 93000 Bobigny

France

6 :	Service des maladies du sang

Hôpital du Haut-Lévêque – CHU Bordeaux – Groupe Hospitalier Sud

Pessac

France

7 :	Laboratoire d'Hématologie [Purpan]

Hôpital Purpan – CHU Toulouse – Université Paul Sabatier [UPS] - Toulouse III

Pôle Biologie, Place du Docteur Baylac - TSA 40031 - 31059 Toulouse cedex 9

France

8 :	Service d'Hématologie Hôtel Dieu Nantes

Hôtel Dieu

Nantes

France

résumé :

OBJECTIVES: Investigating relationships between potential occupational risk factors and lymphoid malignancy (LM). METHODS: We conducted a multicenter hospital-based case-control study in France between 2000 and 2004, including 824 incident cases of non-Hodgkin lymphoma (NHL), Hodgkin lymphoma (HL), multiple myeloma, and "lymphoproliferative syndrome" and 752 frequency-matched controls. Data were collected through face-to-face standardized and detailed interviews. RESULTS: Farming was significantly associated with NHL (odds ratio [OR] = 1.4 [1.0 to 2.0]) and, although not significantly, with lymphoproliferative syndrome and multiple myeloma. ORs were higher for longest durations of exposure. Self-declared exposure to pesticides was significantly associated with NHL (OR = 1.8 [1.2 to 2.7]) and HL (OR = 2.2 [1.0 to 4.7]). Neither solvent-related jobs nor self-reported exposure to solvents were related to LM. Systematic screening based on job titles did not evidence any other association. CONCLUSIONS: The results support the hypothesis that farming plays a role in most types of LM.

domaine :

Sciences du Vivant/Santé publique et épidémiologie

langue du texte
intégral :

Anglais

ISSN :

1076-2752

type de publication :

Articles dans des revues avec comité de lecture

DOI :

10.1097/JOM.0b013e3181569a49

journal :

Journal of Occupational & Environmental Medicine

Audience :

internationale

date de publication :

12/2007

volume :

numéro :

page, identifiant, ... :

1339-50

mots-clés auteur :

occupational exposure – farming – risk – lymphoma – case-control study – epidemiology


inserm-00239464, version 1
http://www.hal.inserm.fr/inserm-00239464
oai:www.hal.inserm.fr:inserm-00239464
Contributeur : U754 Secretariat <>
Soumis le : Mardi 5 Février 2008, 18:14:51
Dernière modification le : Mercredi 6 Février 2008, 14:46:33