PMID: identifiant
de la référence Pubmed : |
 |
 (17564585) |
|
| titre : |
|
Maternal alcohol and coffee drinking, parental smoking and childhood leukaemia: a French population-based case-control study. |
|
| auteur(s) : |
|
Florence Menegaux ( ) 1, Mahaut Ripert1, Denis Hémon1, Jacqueline Clavel1 |
|
| laboratoire : |
|
|
|
| résumé : |
|
We investigated the role of maternal alcohol and coffee drinking during pregnancy and that of parental smoking in the aetiology of childhood leukaemia. A French, population-based, case-control study was conducted, comparing 472 [407 acute lymphoblastic leukaemia (ALL) and 62 acute myeloblastic leukaemia] cases of childhood acute leukaemia (AL) and 567 population controls, frequency-matched with cases on age, gender and region of residence. Both case and control mothers filled in a comprehensive self-administered standardised questionnaire, eliciting detailed data on maternal alcohol and coffee consumption during pregnancy and parental smoking before, during and after pregnancy. Maternal alcohol consumption of more than 1 drink per day was related to ALL (OR = 2.8 [95% CI 1.8, 5.9]). While maternal coffee consumption was not significantly related to AL (OR = 1.4 [95% CI 0.9, 2.3]), highest intake of coffee (more than 3 cups per day) during pregnancy was associated with AL in children whose mothers were non-smokers (OR = 1.9 [95% CI 1.0, 3.5]). No association with parental smoking, either maternal or paternal, was observed with AL. The present results suggest a possible role of the highest consumption of alcohol by the mother during pregnancy in the aetiology of childhood AL. |
|
| domaine : |
|
Sciences du Vivant/Santé publique et épidémiologie
|
|
langue du texte
intégral : |
|
Anglais |
|
| ISSN : |
|
0269-5022 |
|
|
| type de publication : |
|
Articles dans des revues avec comité de lecture |
|
| DOI : |
|
10.1111/j.1365-3016.2007.00824.x |
|
| journal : |
|
| Paediatric and Perinatal Epidemiology (Paediatr Perinat Epidemiol) |
| Publisher |
Wiley-Blackwell |
| ISSN |
0269-5022 (eISSN : 1365-3016) |
|
|
| Audience : |
|
non spécifiée |
|
| date de publication : |
|
07/2007 |
|
| volume : |
|
21 |
|
| numéro : |
|
4 |
|
| page, identifiant, ... : |
|
293-9 |
|
|
| mots-clés auteur : |
|
childhood leukaemia – maternal alcohol – parental smoking – maternal caffeine |
|
