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Why Do Children from Socioeconomically Disadvantaged Families Suffer from Poor Health When They Reach Adulthood? A Life-Course Study.
Melchior M., Moffitt T. E., Milne B. J., Poulton R., Caspi A.
American Journal of Epidemiology (2007) 1 - http://www.hal.inserm.fr/inserm-00165622
 (17641151) 
Why Do Children from Socioeconomically Disadvantaged Families Suffer from Poor Health When They Reach Adulthood? A Life-Course Study.
Maria Melchior () 1, 2, 3, Terrie Moffitt1, 2, Barry Milne1, Richie Poulton4, Avshalom Caspi1, 2
1 :  MRC Social, Genetic and Developmental Psychiatry Centre
Institute of psychiatry – King's College London
London
Royaume-Uni
2 :  Department of Psychology and Neuroscience, and Psychiatry and Behavioral Sciences
Institute for Genome Sciences and Policy – Duke University
Durham, NC
États-Unis
3 :  Santé publique et épidémiologie des déterminants professionnels et sociaux de la santé
http://www.u687.idf.inserm.fr/
INSERM : U687 – IFR69 – Université Paris XI - Paris Sud – Université de Versailles Saint-Quentin-en-Yvelines
Hôpital Paul Brousse 16, av Paul Vaillant Couturier 94807 VILLEJUIF
France
4 :  Dunedin School of Medicine
University of Otago
Nouvelle-Zélande
Childhood socioeconomic disadvantage and adult disorders
The authors investigated what risk factors contribute to an excess risk of poor adult health among children who experience socioeconomic disadvantage. Data came from 1,037 children born in Dunedin, New Zealand, in 1972-1973, who were followed from birth to age 32 years (2004-2005). Childhood socioeconomic status (SES) was measured at multiple points between birth and age 15 years. Risk factors evaluated included a familial liability to poor health, childhood/adolescent health characteristics, low childhood intelligence quotient (IQ), exposure to childhood maltreatment, and adult SES. Adult health outcomes evaluated at age 32 years were major depressive disorder, anxiety disorders, tobacco dependence, alcohol or drug dependence, and clustering of cardiovascular disease risk factors. Results showed that low childhood SES was associated with an increased risk of substance dependence and poor physical health in adulthood (for tobacco dependence, sex-adjusted relative risk (RR) = 2.27, 95% confidence interval (CI): 1.41, 3.65; for alcohol or drug dependence, RR = 2.11, 95% CI: 1.16, 3.84; for cardiovascular risk factor status, RR = 2.55, 95% CI: 1.46, 4.46). Together, the risk factors studied here accounted for 55-67% of poor health outcomes among adults exposed to low SES as children. No single risk factor emerged as the prime explanation, suggesting that the processes mediating the link between childhood low SES and adult poor health are multifactorial.
Sciences du Vivant/Santé publique et épidémiologie
Anglais
0002-9262

Articles dans des revues avec comité de lecture
10.1093/aje/kwm155
American Journal of Epidemiology (Am J Epidemiol)
Publisher Oxford University Press (OUP): Policy B
ISSN 0002-9262 (eISSN : 1476-6256)
internationale
19/07/2007
19/07/2007
1

Supported by the U.S. National Institute of Mental Health, the U.K. Medical Research Council and the U.K. Economic and Social Research Council, the William T. Grant Foundation, the Health Research Council of New Zealand, and the Statistics and Research Division of France's Ministry of Health and Social Affairs. T.E.M. and A.C. are Royal Society Wolfson Research Merit Award holders. We thank the Dunedin study members, Unit research staff, study founder Phil Silva, Ph.D, and Alan Taylor.
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