PMID: identifiant
de la référence Pubmed : |
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 (16990408)  |
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| titre : |
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Dietary patterns and risk of colorectal tumors: a cohort of French women of the National Education System (E3N). |
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| auteur(s) : |
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Emmanuelle Kesse1, Françoise Clavel-Chapelon1, Marie-Christine Boutron-Ruault ( ) 1 |
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| laboratoire : |
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| résumé : |
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Little is known about the dietary patterns associated with colorectal tumors along the adenoma-carcinoma sequence. Scores for dietary patterns were obtained by factor analysis in women from the French cohort of the European Prospective Investigation into Cancer and Nutrition (1993-2000). Their association with colorectal tumors was investigated in 516 adenoma cases (175 high-risk adenomas) and 4,804 polyp-free women and in 172 colorectal cancer cases and 67,312 cancer-free women. The authors identified four dietary patterns: "healthy" (vegetables, fruit, yogurt, sea products, and olive oil); "Western" (potatoes, pizzas and pies, sandwiches, sweets, cakes, cheese, cereal products, processed meat, eggs, and butter); "drinker" (sandwiches, snacks, processed meat, and alcoholic beverages); and "meat eaters" (meat, poultry, and margarine). For quartile 4 versus quartile 1, an increased risk of adenoma was observed with high scores of the Western pattern (multivariate relative risk (RR) = 1.39, 95% confidence interval: 1.00, 1.94; p(trend) = 0.03) and the drinker pattern (RR = 1.42, 95% confidence interval: 1.10, 1.83; p(trend) = 0.01). The meat-eaters pattern was positively associated with colorectal cancer risk (for quartile 4 vs. quartile 1: RR = 1.58, 95% confidence interval: 0.98, 2.53; p(trend) = 0.02). Dietary patterns that reflect a Western way of life are associated with a higher risk of colorectal tumors. |
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| domaine : |
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langue du texte
intégral : |
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Anglais |
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| ISSN : |
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0002-9262 |
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| type de publication : |
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Articles dans des revues avec comité de lecture |
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| DOI : |
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10.1093/aje/kwj324 |
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| journal : |
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| date de publication : |
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01/12/2006 |
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date de publication
électronique : |
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21/09/2006 |
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| volume : |
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164 |
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| numéro : |
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11 |
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| page, identifiant, ... : |
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1085-93 |
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| mots-clés auteur : |
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adenoma – cohort studies – colorectal neoplasms – diet – risk – women |
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| Descripteur(s) MeSH : |
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Adenoma – Colorectal Neoplasms – Diet – Educational Status – Factor Analysis – Statistical – Female – Food Habits – France – Humans – Middle Aged – Nutrition Assessment – Prospective Studies – Risk Assessment – Risk Factors |
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| contrat, financement : |
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The study was supported by the French League against Cancer, the European Community, the 3M Company, the Mutuelle Générale de l'Education Nationale, the Institut Gustave Roussy, and the Institut National de la Santé et de la Recherche Médicale. |
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