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Lung cancer mortality and occupational exposure to asbestos among telephone linemen: a historical cohort study in france.
Meguellati-Hakkas D., Cyr D., Stücker I., Févotte J., Pilorget C., Luce D., Guénel P.
J Occup Environ Med 48, 11 (2006) 1166-72 - http://www.hal.inserm.fr/inserm-00115650
(17099453)
Lung cancer mortality and occupational exposure to asbestos among telephone linemen: a historical cohort study in france.
Djamila Meguellati-Hakkas1, Diane Cyr2, Isabelle Stücker1, Joëlle Févotte3, Corinne Pilorget3, Danièle Luce2, Pascal Guénel1
1 :  Epidémiologie environnementale des cancers
http://ifr69.vjf.inserm.fr/u754/
INSERM : IFR69 – Université Paris XI - Paris Sud
16, Avenue Paul Vaillant-Couturier 94807 VILLEJUIF CEDEX
France
2 :  Santé publique et épidémiologie des déterminants professionnels et sociaux de la santé
http://www.u687.idf.inserm.fr/
INSERM : U687 – IFR69 – Université Paris XI - Paris Sud – Université de Versailles Saint-Quentin-en-Yvelines
Hôpital Paul Brousse 16, av Paul Vaillant Couturier 94807 VILLEJUIF
France
3 :  UMRESTTE - Unité Mixte de Recherche Epidémiologique et de Surveillance Transport Travail Environnement
INRETS – INVS – Université Claude Bernard - Lyon I
25, Avenue François Mitterrand, F-69675 BRON Cédex
France
OBJECTIVE:: The authors studied the mortality by lung cancer in telephone linemen exposed to asbestos at low levels during installation of telephone cables. METHODS:: Three hundred eight lung cancers deaths were identified in the cohort. Exposure to asbestos and to other occupational carcinogens was assessed using a job-exposure matrix. RESULTS:: The relative risk for lung cancer death associated with an estimated exposure of approximately 2 f/cc-years was 2.1 (95% confidence interval = 1.1-4.0) as compared with workers exposed to less than 0.5 f/cc-years. Mean annual exposure or exposure duration were not clearly related to lung cancer. Adjustment for other occupational lung carcinogens did not change this finding. CONCLUSION:: The observed mortality by lung cancer associated with asbestos exposure at low levels is higher than the prediction based on linear downward extrapolations from highly exposed occupational cohorts.
Sciences du Vivant/Santé publique et épidémiologie
Sciences du Vivant/Médecine humaine et pathologie/Pneumologie et système respiratoire
Anglais
1076-2752

Articles dans des revues avec comité de lecture
10.1097/01.jom.0000243357.70143.47
J Occup Environ Med
internationale
11/2006
48
11
1166-72