PMID: identifier of
Pubmed reference: |
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 (20185973)  |
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| title: |
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Hostility May Explain the Association between Depressive Mood and Mortality: Evidence from the French GAZEL Cohort Study. |
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| author(s): |
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Cédric Lemogne ( ) 1, 2, Hermann Nabi3, Marie Zins3, 4, Sylvaine Cordier5, Pierre Ducimetière6, Marcel Goldberg3, Silla Consoli1 |
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| laboratory: |
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| short title : |
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Hostility, depression and mortality. |
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| abstract: |
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Background: Depressive mood is associated with mortality. Because personality has been found to be associated with depression and mortality as well, we aimed to test whether depressive mood could predict mortality when adjusting for several measures of personality. Methods: 20,625 employees of the French national gas and electricity companies gave consent to enter in the GAZEL cohort in 1989. Questionnaires were mailed in 1993 to assess depressive mood, type A behavior pattern, hostility, and the six personality types proposed by Grossarth-Maticek and Eysenck. Vital status and date of death were obtained annually for all participants. The association between psychological variables and mortality was measured by the Relative Index of Inequality (RII) computed through Cox regression. Results: 14,356 members of the GAZEL cohort (10,916 men, mean age: 49 years; 3,965 women, mean age: 46 years) completed the depressive mood scale and at least one personality scale. During a mean follow-up of 14.8 years, 687 participants had died. Depressive mood predicted mortality, even after adjustment for age, sex, education level, body mass index, alcohol consumption, and smoking [RII (95% CI) = 1.56 (1.16-2.11)]. However, this association was dramatically reduced (RII reduction: 78.9%) after further adjustment for cognitive hostility (i.e. hostile thoughts) [RII (95% CI) = 1.12 (0.80-1.57)]. Cognitive hostility was the only personality measure remaining associated with mortality after adjustment for depressive mood [RII (95% CI) = 1.97 (1.39-2.77)]. Conclusions: Cognitive hostility may either confound or mediate the association between depressive mood and mortality. |
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| subject: |
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Life Sciences/Health Care Sciences and Epidemiology
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| fulltext language: |
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English |
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| ISSN: |
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0033-3190 |
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| publication format: |
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Article in peer-reviewed journal |
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| DOI: |
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10.1159/000286961 |
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| journal: |
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| Psychotherapy and Psychosomatics (Psychother Psychosom) |
| Publisher |
Karger |
| ISSN |
0033-3190 (eISSN : 1423-0348) |
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| Audience: |
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international |
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| publication date: |
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2010-02-20 |
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| submission date: |
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2010-02-20 |
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| volume: |
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79 |
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| issue: |
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3 |
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| page, identifiant, ...: |
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164-171 |
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| keyword(s) of author: |
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Cohort – Depression – Hostility – Mood – Mortality – Personality |
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| contract, financing: |
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The GAZEL cohort is supported by Electricité de France-Gaz de France (EDF-GDF). The personality data collection was funded by the Caisse Nationale d‟Assurance Maladie and by the Ligue Nationale contre le Cancer. |
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