PMID: identifier of
Pubmed reference: |
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 (18301178) |
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| title: |
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Hepatocellular Carcinoma and Occupation in Men: A Case-Control Study. |
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| author(s): |
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Jean-François Ferrand1, Sylvie Cénée1, Pierre Laurent-Puig2, Marie-Anne Loriot2, Jean-Claude Trinchet3, Françoise Degos4, Jean-Pierre Bronovicky, Gilles Pelletier5, Isabelle Stücker ( ) 1 |
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| laboratory: |
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| abstract: |
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OBJECTIVE:: The principal objective of this work was to evaluate the association between the risk of hepatocellular carcinoma (HCC) and various occupations. METHODS:: This case-control study, conducted during 2000 to 2003 in four French hospitals, included 125 men younger than 75 years with incident HCC and 142 men as control subjects. RESULTS:: An association with HCC was observed for machinery fitters and machine assemblers (odds ratio [OR] = 4.4 [1.0-19.0], eight exposed cases and three exposed controls). A higher percentage of cases than controls were metal machinists (OR = 2.2 [0.8-5.8], 14 exposed cases and 10 exposed controls), although the difference was not statistically significant. These associations were strongest for subjects with duration of employment greater than 20 years. CONCLUSIONS:: Our findings suggest an association between metal machining jobs and hepatocellular carcinoma, although we cannot rule out the possibility that it was observed by chance. |
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| subject: |
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Life Sciences/Health Care Sciences and Epidemiology
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| fulltext language: |
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English |
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| ISSN: |
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1076-2752 |
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| publication format: |
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Article in peer-reviewed journal |
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| DOI: |
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10.1097/JOM.0b013e31815d88e2 |
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| journal: |
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Journal of Occupational & Environmental Medicine |
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| Audience: |
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international |
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| publication date: |
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2008-02 |
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| volume: |
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50 |
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| issue: |
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2 |
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| page, identifiant, ...: |
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212-220 |
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