PMID: identifier of
Pubmed reference: |
 |
 (18466566)  |
|
| title: |
|
Power of the 2-locus TDT for testing the interaction of two susceptibility genes. |
|
| author(s): |
|
Salma Kotti ( ) 1, Mathieu Bourgey1, Françoise Clerget-Darpoux1 |
|
| laboratory: |
|
|
|
| abstract: |
|
ABSTRACT : We recently proposed a new strategy: 2-locus TDT for detecting two susceptibility genes through their interaction in trio families. We apply our method to two candidate genes, A and C, on the Genetic Analysis Workshop 15 (GAW15) simulated rheumatoid arthritis data and study the power to identify an interactive effect of these genes.This study was performed with full knowledge of the answers. |
|
| subject: |
|
Life Sciences/Genetics
|
|
| fulltext language: |
|
English |
|
| ISSN: |
|
1753-6561 |
|
|
| publication format: |
|
Article in peer-reviewed journal |
|
| journal: |
|
| BMC Proceedings (BMC Proc) |
| Publisher |
BioMed Central |
| ISSN |
1753-6561 |
|
|
| Audience: |
|
international |
|
| publication date: |
|
2007 |
|
| submission date: |
|
2007-12-18 |
|
| volume: |
|
1 Suppl 1 |
|
| issue: |
|
Suppl 1 |
|
| page, identifiant, ...: |
|
S65 |
|
|
| contract, financing: |
|
Fondation pour la Recherche Médicale |
|
