PMID: identifier of
Pubmed reference: |
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 (15961621)  |
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| title: |
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Twenty five year mortality and air pollution: results from the French PAARC survey. |
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| author(s): |
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Laurent Filleul ( ) 1, Virginie Rondeau2, Stéphanie Vandentorren1, Nicole Le Moual3, Anne Cantagrel1, Isabella Annesi-Maesano3, Denis Charpin4, Christophe Declercq5, Françoise Neukirch6, Christophe Paris7, Daniel Vervloet4, Patrick Brochard1, Jean-François Tessier1, Francine Kauffmann3, Isabelle Baldi1 |
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| laboratory: |
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| abstract: |
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AIMS AND METHODS: Long term effects of air pollution on mortality were studied in 14,284 adults who resided in 24 areas from seven French cities when enrolled in the PAARC survey (air pollution and chronic respiratory diseases) in 1974. Daily measurements of sulphur dioxide, total suspended particles, black smoke, nitrogen dioxide, and nitric oxide were made in 24 areas for three years (1974-76). Cox proportional hazards models controlling for individual confounders (smoking, educational level, body mass index, occupational exposure) were applied, and frailty models used to take into account spatial correlation. Indicators of air pollution were the mean concentration. RESULTS: Models were run before and after exclusion of six area monitors influenced by local traffic (NO/NO2 >3 in ppb). After exclusion of these areas, analyses showed that adjusted risk ratios (95% CI) for TSP, BS, NO2, and NO for non-accidental mortality were 1.05 (1.02 to 1.08), 1.07 (1.03 to 1.10), 1.14 (1.03 to 1.25), and 1.11 (1.05 to 1.17) for 10 microg/m3 respectively. Consistent patterns for lung cancer and cardiopulmonary causes were observed. CONCLUSIONS: Urban air pollution assessed in the 1970s was associated with increased mortality over 25 years in France. |
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| subject: |
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Life Sciences/Health Care Sciences and Epidemiology
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| fulltext language: |
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English |
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| ISSN: |
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1351-0711 |
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| publication format: |
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Article in peer-reviewed journal |
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| DOI: |
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10.1136/oem.2004.014746 |
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| journal: |
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Occup Environ Med |
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| publication date: |
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2005-07 |
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| volume: |
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62 |
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| issue: |
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7 |
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| page, identifiant, ...: |
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453-60 |
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| MeSH Descriptor(s): |
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Adult – Age Distribution – Air Pollution – Body Mass Index – Cardiovascular Diseases – Cause of Death – Environmental Exposure – Environmental Monitoring – Epidemiologic Methods – Female – France – Humans – Lung Neoplasms – Male – Mortality – Sex Distribution – Smoking |
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