PMID: identifier of
Pubmed reference: |
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 (16278693)  |
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| title: |
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Prescreening tools for diabetes and obesity-associated dyslipidaemia: comparing BMI, waist and waist hip ratio. The D.E.S.I.R. Study. |
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| author(s): |
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Beverley Balkau ( ) 1, David Sapinho1, Anne Petrella2, Leila Mhamdi1, Martine Cailleau3, Dominique Arondel4, Marie-Aline Charles1, For the DESIR group collaboration(s) |
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| laboratory: |
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| short title : |
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Screening for undiagnosed diabetes and dyslipidaemia |
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| abstract: |
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OBJECTIVE: To compare the sensitivities of BMI, waist circumference and waist hip ratio (WHR) in identifying subjects who should be screened for diabetes and/or for obesity-associated dyslipidaemia. DESIGN: Cross-sectional study. SETTING: Central-western France. PARTICIPANTS: More than 3000 men and women, aged 40-64 years, from the French study: data from an epidemiological study on the insulin resistance syndrome (D.E.S.I.R.). MAIN OUTCOME MEASURES: Sensitivity and specificity for screened diabetes (fasting plasma glucose>or=7.0 mmol/l) and screened dyslipidaemia (triglycerides>or=2.3 mmol/l and/or HDL-cholesterol <0.9/1.1 mmol/l (men/women)) according to BMI, waist circumference and WHR. RESULTS: Sensitivities increased as more corpulent subjects were screened, but they increased slowly after screening the top 30%: body mass index (BMI)>or=27/26 kg/m(2) (men/women) or waist >or=96/83 cm or WHR>or=0.96/0.83. These values were chosen as thresholds. In men, BMI had a nonsignificantly higher sensitivity than waist or WHR for both diabetes and dyslipidaemia (77 vs 74 and 66% P<0.3, 0.09; 56 vs 54 and 49% P<0.5, 0.16). For women, waist had a slightly higher sensitivity than BMI or WHR (82 vs 77 and 77% P<0.8, 0.7) for diabetes; for dyslipidaemia, waist and WHR had similar sensitivities, higher than for BMI (65 and 67 vs 54% P<0.16, 0.13). CONCLUSIONS: We propose that for screening in a French population 40-64 years of age, the more obese 30% of the population, identified either by BMI, waist or WHR be screened for diabetes and obesity-associated dyslipidaemia. |
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| subject: |
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| fulltext language: |
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English |
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| ISSN: |
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0954-3007 |
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| publication format: |
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Article in peer-reviewed journal |
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| DOI: |
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10.1038/sj.ejcn.1602308 |
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| journal: |
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Eur J Clin Nutr |
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| Audience: |
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international |
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| publication date: |
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2006-03 |
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| volume: |
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60 |
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| issue: |
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3 |
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| page, identifiant, ...: |
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295-304 |
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| MeSH Descriptor(s): |
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Adult – Analysis of Variance – Body Composition – Body Mass Index – Cross-Sectional Studies – Diabetes Mellitus – Type 2 – Dyslipidemias – Female – France – Humans – Insulin Resistance – Male – Mass Screening – Middle Aged – Obesity – Risk Factors – Sensitivity and Specif |
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