Ectopic pregnancy is again on the increase. Recent trends in the incidence of ectopic pregnancies in France (1992-2002).

Joël Coste; Jean BOUYER; Sylvie Ughetto; Laurent Gerbaud; Hervé Fernandez; Jean-Luc Pouly; Nadine Job-Spira

inserm-00086394, version 1

Ectopic pregnancy is again on the increase. Recent trends in the incidence of ectopic pregnancies in France (1992-2002).
Coste J., BOUYER J., Ughetto S., Gerbaud L., Fernandez H., Pouly J.-L., Job-Spira N.
Hum Reprod 19 (2004) 2014-8 - http://www.hal.inserm.fr/inserm-00086394

PMID: identifier of
Pubmed reference:

(15256504)

title:

Ectopic pregnancy is again on the increase. Recent trends in the incidence of ectopic pregnancies in France (1992-2002).

author(s):

Joël Coste¹, Jean BOUYER¹, Sylvie Ughetto², Laurent Gerbaud², Hervé Fernandez³, Jean-Luc Pouly⁴, Nadine Job-Spira¹

laboratory:

1:	Epidémiologie, Démographie et Sciences Sociales: santé reproductive, sexualité et infection à VIH

INSERM : U569 – INED – IFR69 – Université Paris XI - Paris Sud

Secteur Bleu 82, Rue du General Leclerc 94276 LE KREMLIN BICETRE CEDEX

France

2:	Service Épidémiologie, Prévention et Économie de la Santé

CHU Clermont-Ferrand

Clermont-Ferrand

France

3:	Service de gynécologie-obstétrique, médecine de la reproduction [Béclère]

Assistance publique - Hôpitaux de Paris (AP-HP) – Hôpital Antoine Béclère – Université Paris XI - Paris Sud

157, rue de la Porte de Trivaux 92141 Clamart

France

4:	Service de Gynéco-Obstétrique

CHU Clermont-Ferrand

Clermont-Ferrand

France

abstract:

BACKGROUND: We aimed to assess the recent incidence trends of ectopic pregnancies (EP) in France (1992-2002). METHODS: A population-based register of all women aged 15-44 years with EP was set up in Auvergne (central France). We calculated rates of EP as a 'reproductive failure' or as a 'contraceptive failure', frequencies of exposure to the two main risk factors for EP (cigarette smoking and chlamydial infection) and contraceptive methods between 1992 and 2002. RESULTS: The overall EP rate decreased by 2%, from 96.4 per 100 000 women aged 15-44 in 1992 to 95.3 per 100 000 in 2002. However, the rate of 'reproductive failure' EP increased by 17%, while the rate of 'contraceptive failure' EP, mostly intrauterine device failure, decreased by 29%. CONCLUSION: Appropriate analysis reveals that the rate of EP as reproductive failure is increasing again in France. This result is of interest for many European and North America countries where chlamydial infections or smoking or both are increasing in women of reproductive age. The rates of EP as contraceptive failure and of that as reproductive failure evolve differently in the population and should not be confused in epidemiological studies.

subject:

Life Sciences/Health Care Sciences and Epidemiology

Life Sciences/Human health and pathology/Obstetrics & Gynecology

fulltext language:

English

ISSN:

0268-1161

publication format:

Article in peer-reviewed journal

DOI:

10.1093/humrep/deh399

journal:

Hum Reprod

publication date:

2004

volume:

page, identifiant, ...:

2014-8

MeSH Descriptor(s):

Adolescent – Adult – Age Distribution – Chlamydia Infections – Contraception – Female – France – Humans – Incidence – Intrauterine Devices – Pregnancy – Ectopic – Research Support – Non-U.S. Gov't – Smoking – Adolescent – Chlamydia Inf


inserm-00086394, version 1
http://www.hal.inserm.fr/inserm-00086394
oai:www.hal.inserm.fr:inserm-00086394
From: Nadine Kaniewski <>
Submitted on: Tuesday, 18 July 2006 15:49:43
Updated on: Monday, 7 August 2006 16:24:33