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Socioeconomic Status, Structural and Functional Measures of Social Support, and Mortality: The British Whitehall II Cohort Study, 1985-2009.
Stringhini S., Berkman L., Dugravot A., Ferrie J. E., Marmot M., Kivimaki M., Singh-Manoux A.
American Journal of Epidemiology 175, 12 (2012) 1275-83 - http://www.hal.inserm.fr/inserm-00710252
 (22534202) 
Socioeconomic Status, Structural and Functional Measures of Social Support, and Mortality: The British Whitehall II Cohort Study, 1985-2009.
Silvia Stringhini1, 2, Lisa Berkman3, Aline Dugravot1, Jane Ferrie4, Michael Marmot5, Mika Kivimaki5, Archana Singh-Manoux () 1, 5, 6
1 :  CESP - Centre de recherche en épidémiologie et santé des populations
INSERM : U1018 – Université Paris XI - Paris Sud – Hôpital Paul Brousse – Assistance publique - Hôpitaux de Paris (AP-HP)
16 avenue Paul Vaillant Couturier 94807 Villejuif Cedex, France
France
2 :  UPC - Community Prevention Unit
University Institute of Social and Preventive Medicine (IUMSP)
Lausanne
Suisse
3 :  Harvard Center for Population and Development Studies
Harvard Center for Population and Development Studies
9 Bow Street, Cambridge, MA
États-Unis
4 :  School of Community and Social Medicine
University of Bristol
Bristol
Royaume-Uni
5 :  Department of Epidemiology and Public Health
http://www.ucl.ac.uk/epidemiology/staff/singh-manoux.htm
University College of London (UCL)
1-19 Torrington Place London WC1E 6BT
Royaume-Uni
6 :  Centre de Gérontologie
Assistance publique - Hôpitaux de Paris (AP-HP) – Sainte-Périne - Rossini - Chardon-Lagache : Hôpitaux Universitaires Paris Ile-de-France Ouest
11, rue Chardon-Lagache 75016 Paris 16ème
France
The authors examined the associations of social support with socioeconomic status (SES) and with mortality, as well as how SES differences in social support might account for SES differences in mortality. Analyses were based on 9,333 participants from the British Whitehall II Study cohort, a longitudinal cohort established in 1985 among London-based civil servants who were 35-55 years of age at baseline. SES was assessed using participant's employment grades at baseline. Social support was assessed 3 times in the 24.4-year period during which participants were monitored for death. In men, marital status, and to a lesser extent network score (but not low perceived support or high negative aspects of close relationships), predicted both all-cause and cardiovascular mortality. Measures of social support were not associated with cancer mortality. Men in the lowest SES category had an increased risk of death compared with those in the highest category (for all-cause mortality, hazard ratio = 1.59, 95% confidence interval: 1.21, 2.08; for cardiovascular mortality, hazard ratio = 2.48, 95% confidence interval: 1.55, 3.92). Network score and marital status combined explained 27% (95% confidence interval: 14, 43) and 29% (95% confidence interval: 17, 52) of the associations between SES and all-cause and cardiovascular mortality, respectively. In women, there was no consistent association between social support indicators and mortality. The present study suggests that in men, social isolation is not only an important risk factor for mortality but is also likely to contribute to differences in mortality by SES.
Sciences du Vivant/Santé publique et épidémiologie
Anglais
0002-9262

Articles dans des revues avec comité de lecture
10.1093/aje/kwr461
American Journal of Epidemiology (Am J Epidemiol)
Publisher Oxford University Press (OUP): Policy B
ISSN 0002-9262 (eISSN : 1476-6256)
internationale
15/06/2012
24/04/2012
175
12
1275-83

AS-M is supported by a "European Young Investigator Award" from the European Science Foundation and the National Institute on Aging, NIH, US (R01AG013196 and R01AG034454). MK is supported by the BUPA Foundation, the Academy of Finland and the EU New OSH ERA research programme. The Whitehall II study has been supported by grants from the British Medical Research Council (MRC); the British Heart Foundation; the British Health and Safety Executive; the British Department of Health; the National Heart, Lung, and Blood Institute (R01HL036310); the National Institute on Aging, NIH.
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