A. Zwerling, M. Behr, A. Verma, T. Brewer, D. Menzies et al., The BCG World Atlas: A Database of Global BCG Vaccination Policies and Practices, PLoS Medicine, vol.82, issue.3, 2011.
DOI : 10.1371/journal.pmed.1001012.t003

A. Morales, D. Eidinger, and A. Bruce, Intracavitary Bacillus Calmette-guerin in the Treatment of Superficial Bladder Tumors, The Journal of Urology, vol.116, issue.2, pp.180-183, 1976.
DOI : 10.1016/S0022-5347(17)58737-6

S. Brandau and H. Suttmann, Thirty years of BCG immunotherapy for non-muscle invasive bladder cancer: A success story with room for improvement, Biomedicine & Pharmacotherapy, vol.61, issue.6, pp.299-305, 2007.
DOI : 10.1016/j.biopha.2007.05.004

D. Lamm, Efficacy and Safety of Bacille Calmette-Guerin Immunotherapy in Superficial Bladder Cancer, Clinical Infectious Diseases, vol.31, issue.Supplement 3, pp.31-86, 2000.
DOI : 10.1086/314064

M. Pai, A. Zwerling, and D. Menzies, Systematic Review: T-Cell???based Assays for the Diagnosis of Latent Tuberculosis Infection: An Update, Annals of Internal Medicine, vol.149, issue.3, pp.177-84, 2008.
DOI : 10.7326/0003-4819-149-3-200808050-00241

D. Duffy, V. Rouilly, V. Libri, M. Hasan, B. Beitz et al., Functional Analysis via Standardized Whole-Blood Stimulation Systems Defines the Boundaries of a Healthy Immune Response to Complex Stimuli, Immunity, vol.40, issue.3, pp.436-50, 2014.
DOI : 10.1016/j.immuni.2014.03.002

URL : https://hal.archives-ouvertes.fr/pasteur-01384537

H. Larue, C. Ayari, A. Bergeron, and Y. Fradet, Toll-like receptors in urothelial cells???targets for cancer immunotherapy, Nature Reviews Urology, vol.1, issue.9, pp.537-582, 2013.
DOI : 10.1016/j.vaccine.2006.04.048

J. Kleinnijenhuis, M. Oosting, L. Joosten, M. Netea, and R. Van-crevel, Innate immune recognition of Mycobacterium tuberculosis, Clin Dev Immunol, pp.405310-405320, 2011.

M. Yadav and J. Schorey, The beta-glucan receptor dectin-1 functions together with TLR2 to mediate macrophage activation by mycobacteria, Blood, vol.108, issue.9, pp.3168-75, 2006.
DOI : 10.1182/blood-2006-05-024406

A. Yonekawa, S. Saijo, Y. Hoshino, Y. Miyake, E. Ishikawa et al., Dectin-2 Is a Direct Receptor for Mannose-Capped Lipoarabinomannan of Mycobacteria, Immunity, vol.41, issue.3, pp.402-415, 2014.
DOI : 10.1016/j.immuni.2014.08.005

S. Thomas, V. Rouilly, E. Patin, C. Alanio, A. Dubois et al., The Milieu Int??rieur study ??? An integrative approach for study of human immunological variance, Clinical Immunology, vol.157, issue.2, pp.277-93, 2015.
DOI : 10.1016/j.clim.2014.12.004

C. Lu and R. King, An investigation into the population abundance distribution of mRNAs, proteins, and metabolites in biological systems, Bioinformatics, vol.25, issue.16, pp.2020-2027, 2009.
DOI : 10.1093/bioinformatics/btp360

D. Rasch, F. Teuscher, and V. Guiard, How robust are tests for two independent samples?, Journal of Statistical Planning and Inference, vol.137, issue.8, pp.2706-2726, 2007.
DOI : 10.1016/j.jspi.2006.04.011

A. Cooper, K. Mayer-barber, and A. Sher, Role of innate cytokines in mycobacterial infection, Mucosal Immunology, vol.8, issue.3, pp.252-60, 2011.
DOI : 10.1084/jem.20091750

M. Lalor, S. Smith, S. Floyd, P. Gorak-stolinska, R. Weir et al., Complex cytokine profiles induced by BCG vaccination in UK infants, Vaccine, vol.28, issue.6, pp.1635-1676, 2010.
DOI : 10.1016/j.vaccine.2009.11.004

URL : http://doi.org/10.1016/j.vaccine.2009.11.004

P. Mendez-samperio, A. Vazquez, and H. Ayala, Infection of human monocytes with Mycobacterium bovis BCG induces production of CC-chemokines, Journal of Infection, vol.47, issue.2, pp.139-186, 2003.
DOI : 10.1016/S0163-4453(03)00010-0

S. Atkinson, E. Valadas, S. Smith, P. Lukey, and H. Dockrell, Monocyte-derived macrophage cytokine responses induced by M. bovis BCG, Tubercle and Lung Disease, vol.80, issue.4-5, pp.197-207, 2000.
DOI : 10.1054/tuld.2000.0247

E. Ishikawa, D. Mori, and S. Yamasaki, Recognition of Mycobacterial Lipids by Immune Receptors, Trends in Immunology, vol.38, issue.1, pp.66-76, 2016.
DOI : 10.1016/j.it.2016.10.009

S. Tsuji, M. Matsumoto, O. Takeuchi, S. Akira, I. Azuma et al., Maturation of Human Dendritic Cells by Cell Wall Skeleton of Mycobacterium bovis Bacillus Calmette-Guerin: Involvement of Toll-Like Receptors, Infection and Immunity, vol.68, issue.12, pp.6883-90, 2000.
DOI : 10.1128/IAI.68.12.6883-6890.2000

J. Schorey and C. Lawrence, The Pattern Recognition Receptor Dectin-1: From Fungi to Mycobacteria, Current Drug Targets, vol.9, issue.2, pp.123-132, 2008.
DOI : 10.2174/138945008783502430

URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664456/pdf

F. Hayashi, K. Smith, A. Ozinsky, T. Hawn, E. Yi et al., The innate immune response to bacterial flagellin is mediated by toll-like receptor 5, Nature, vol.410, issue.6832, pp.1099-103, 2001.
DOI : 10.1038/35074106

A. Werman, R. Werman-venkert, R. White, J. Lee, B. Werman et al., The precursor form of IL-1?? is an intracrine proinflammatory activator of transcription, Proceedings of the National Academy of Sciences, vol.418, issue.6894, pp.2434-2443, 2004.
DOI : 10.1038/nature00858

J. Willment, A. Marshall, D. Reid, D. Williams, S. Wong et al., The human ?-glucan receptor is widely expressed and functionally equivalent to murine Dectin-1 on primary cells, European Journal of Immunology, vol.165, issue.5, pp.1539-1586, 2005.
DOI : 10.4049/jimmunol.165.11.6037

N. Cortez-espinosa, M. Garcia-hernandez, E. Reynaga-hernandez, J. Cortes-garcia, N. Corral-fernandez et al., Abnormal expression and function of Dectin-1 receptor in type 2 diabetes mellitus patients with poor glycemic control (HbA1c>8%), Metabolism, vol.61, issue.11, pp.611538-611584, 2012.
DOI : 10.1016/j.metabol.2012.03.020

M. Morgan and Z. Liu, Crosstalk of reactive oxygen species and NF-kappaB signaling, Cell Res, vol.21, issue.1, 2011.
DOI : 10.1038/cr.2010.178

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3193400

G. Gloire, S. Legrand-poels, and J. Piette, NF-??B activation by reactive oxygen species: Fifteen years later, Biochemical Pharmacology, vol.72, issue.11, pp.1493-505, 2006.
DOI : 10.1016/j.bcp.2006.04.011

J. Rawlings, K. Rosler, and D. Harrison, The JAK/STAT signaling pathway, Journal of Cell Science, vol.117, issue.8, pp.1281-1284, 2004.
DOI : 10.1242/jcs.00963

S. Verstovsek, H. Kantarjian, R. Mesa, A. Pardanani, J. Cortes-franco et al., Safety and Efficacy of INCB018424, a JAK1 and JAK2 Inhibitor, in Myelofibrosis, New England Journal of Medicine, vol.363, issue.12, pp.1117-2710, 1056.
DOI : 10.1056/NEJMoa1002028

O. Shea, J. Kontzias, A. Yamaoka, K. Tanaka, Y. Laurence et al., Janus kinase inhibitors in autoimmune diseases, Annals of the Rheumatic Diseases, vol.72, issue.suppl 2, pp.111-116, 2013.
DOI : 10.1136/annrheumdis-2012-202576

O. Takeuchi and S. Akira, Pattern Recognition Receptors and Inflammation, Cell, vol.140, issue.6, pp.805-825, 2010.
DOI : 10.1016/j.cell.2010.01.022

URL : http://doi.org/10.1016/j.cell.2010.01.022

H. Goodridge, C. Reyes, C. Becker, T. Katsumoto, J. Ma et al., Activation of the innate immune receptor Dectin-1 upon formation of a ???phagocytic synapse???, Nature, vol.177, issue.7344, pp.471-476, 2011.
DOI : 10.4049/jimmunol.177.12.8667

A. Jankowski, C. Scott, and S. Grinstein, Determinants of the Phagosomal pH in Neutrophils, Journal of Biological Chemistry, vol.269, issue.8, pp.6059-66, 2002.
DOI : 10.1042/bj2460325

G. Napolitani, A. Rinaldi, F. Bertoni, F. Sallusto, and A. Lanzavecchia, Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1???polarizing program in dendritic cells, Nature Immunology, vol.266, issue.8, pp.769-7610, 1038.
DOI : 10.1016/S0022-1759(98)00204-X

A. Bagchi, E. Herrup, H. Warren, J. Trigilio, H. Shin et al., MyD88-Dependent and MyD88-Independent Pathways in Synergy, Priming, and Tolerance between TLR Agonists, The Journal of Immunology, vol.178, issue.2, pp.1164-71, 2007.
DOI : 10.4049/jimmunol.178.2.1164

J. Duggan, D. You, J. Cleaver, D. Larson, R. Garza et al., Synergistic Interactions of TLR2/6 and TLR9 Induce a High Level of Resistance to Lung Infection in Mice, The Journal of Immunology, vol.186, issue.10, pp.5916-5942, 2011.
DOI : 10.4049/jimmunol.1002122

D. Underhill, Collaboration between the innate immune receptors dectin-1, TLRs, and Nods, Immunological Reviews, vol.172, issue.1, pp.75-87, 2007.
DOI : 10.4049/jimmunol.172.8.4733

L. Yamashiro, S. Oliveira, and A. Bafica, Innate immune sensing of nucleic acids from mycobacteria, Microbes and Infection, vol.16, issue.12, pp.991-998, 2014.
DOI : 10.1016/j.micinf.2014.09.006

R. Watson, S. Bell, D. Macduff, J. Kimmey, E. Diner et al., The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy, Cell Host & Microbe, vol.17, issue.6, pp.811-820, 2015.
DOI : 10.1016/j.chom.2015.05.004

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466081

A. Cappuccio, R. Zollinger, M. Schenk, A. Walczak, N. Servant et al., Combinatorial code governing cellular responses to complex stimuli, Nature Communications, vol.449, 2015.
DOI : 10.1038/nature06116

URL : http://doi.org/10.1038/ncomms7847

A. Urrutia, D. Duffy, V. Rouilly, C. Posseme, R. Djebali et al., Standardized Whole-Blood Transcriptional Profiling Enables the Deconvolution of Complex Induced Immune Responses, Cell Reports, vol.16, issue.10, pp.2777-91, 2016.
DOI : 10.1016/j.celrep.2016.08.011

URL : https://hal.archives-ouvertes.fr/pasteur-01367555

C. Biot, C. Rentsch, J. Gsponer, F. Birkhauser, H. Jusforgues-saklani et al., Preexisting BCG-Specific T Cells Improve Intravesical Immunotherapy for Bladder Cancer, Science Translational Medicine, vol.147, issue.12, 2012.
DOI : 10.4049/jimmunol.0803974

URL : https://hal.archives-ouvertes.fr/pasteur-01402032

C. Bilen, K. Inci, I. Erkan, and H. Ozen, The Predictive Value Of Purified Protein Derivative Results On Complications And Prognosis In Patients With Bladder Cancer Treated With Bacillus Calmette-Guerin, The Journal of Urology, vol.169, issue.5, pp.1702-1707, 2003.
DOI : 10.1097/01.ju.0000059681.67567.12

K. Taniguchi, S. Koga, M. Nishikido, S. Yamashita, T. Sakuragi et al., Systemic immune response after intravesical instillation of bacille Calmette-Guerin (BCG) for superficial bladder cancer, Clinical and Experimental Immunology, vol.157, issue.1, pp.131-136, 1999.
DOI : 10.1097/00005392-199602000-00016