A. Palumbo and K. Anderson, Multiple Myeloma, New England Journal of Medicine, vol.364, issue.11, pp.1046-1060, 2011.
DOI : 10.1056/NEJMra1011442

URL : https://hal.archives-ouvertes.fr/hal-01282339

W. Chng, A. Dispenzieri, and C. Chim, IMWG consensus on risk stratification in multiple myeloma, Leukemia, vol.8, issue.2, pp.269-277, 2014.
DOI : 10.1371/journal.pone.0066361

P. Greipp, S. Miguel, J. Durie, and B. , International staging system for multiple myeloma [published correction appears, J Clin Oncol. J Clin Oncol, vol.2323, issue.2515, pp.6281-3412, 2005.

H. Avet-loiseau, B. Durie, and M. Cavo, Combining fluorescent in situ hybridization data with ISS staging improves risk assessment in myeloma: an International Myeloma Working Group collaborative project, Leukemia, vol.88, issue.3, pp.711-717, 2013.
DOI : 10.1200/JCO.2011.36.5726

A. Palumbo, H. Avet-loiseau, and S. Oliva, Revised International Staging System for Multiple Myeloma: A Report From International Myeloma Working Group, Journal of Clinical Oncology, vol.33, issue.26, pp.2863-2869, 2015.
DOI : 10.1200/JCO.2015.61.2267

C. Théryth´théry, L. Zitvogel, and S. Amigorena, Exosomes: composition, biogenesis and function, Nat Rev Immunol, vol.2, issue.8, pp.569-579, 2002.

H. Peinado, M. Ale?kovi´ale?kovi´c, and S. Lavotshkin, Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET, Nature Medicine, vol.26, issue.6, pp.883-891, 2012.
DOI : 10.1093/jnci/djq153

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3645291

A. Roccaro, A. Sacco, and P. Maiso, BM mesenchymal stromal cell???derived exosomes facilitate multiple myeloma progression, Journal of Clinical Investigation, vol.123, issue.4, pp.1542-1555, 2013.
DOI : 10.1172/JCI66517DS1

URL : http://www.jci.org/articles/view/66517/files/pdf

S. Melo, H. Sugimoto, O. Connell, and J. , Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis, Cancer Cell, vol.26, issue.5, pp.707-721, 2014.
DOI : 10.1016/j.ccell.2014.09.005

URL : http://doi.org/10.1016/j.ccell.2014.09.005

J. Krol, I. Loedige, and W. Filipowicz, The widespread regulation of microRNA biogenesis, function and decay, Nature Reviews Genetics, vol.36, issue.9, pp.597-610, 2010.
DOI : 10.1038/nrg2843

J. Lu, G. Getz, and E. Miska, MicroRNA expression profiles classify human cancers, Nature, vol.1, issue.7043, pp.834-838, 2005.
DOI : 10.1016/S1535-6108(02)00018-1

F. Pichiorri, S. Suh, and M. Ladetto, MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis, Proceedings of the National Academy of Sciences, vol.101, issue.26, pp.12885-12890, 2008.
DOI : 10.1073/pnas.0403293101

URL : http://www.pnas.org/content/105/35/12885.full.pdf

N. Gutí-errez, M. Sarasquete, and I. Misiewicz-krzeminska, Deregulation of microRNA expression in the different genetic subtypes of multiple myeloma and correlation with gene expression profiling, Leukemia, vol.24, issue.3, pp.629-637, 2010.
DOI : 10.1038/sj.leu.2404520

G. Calin, M. Ferracin, and A. Cimmino, A MicroRNA Signature Associated with Prognosis and Progression in Chronic Lymphocytic Leukemia, New England Journal of Medicine, vol.353, issue.17, pp.1793-1801, 2005.
DOI : 10.1056/NEJMoa050995

N. Yanaihara, N. Caplen, and E. Bowman, Unique microRNA molecular profiles in lung cancer diagnosis and prognosis, Cancer Cell, vol.9, issue.3, pp.189-198, 2006.
DOI : 10.1016/j.ccr.2006.01.025

URL : http://doi.org/10.1016/j.ccr.2006.01.025

S. Yu, H. Chen, and G. Chang, MicroRNA Signature Predicts Survival and Relapse in Lung Cancer, Cancer Cell, vol.13, issue.1, pp.48-57, 2008.
DOI : 10.1016/j.ccr.2007.12.008

URL : http://doi.org/10.1016/j.ccr.2007.12.008

T. Ueda, S. Volinia, and H. Okumura, Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis, The Lancet Oncology, vol.11, issue.2, pp.136-146, 2010.
DOI : 10.1016/S1470-2045(09)70343-2

N. Liu, N. Chen, and R. Cui, Prognostic value of a microRNA signature in nasopharyngeal carcinoma: a microRNA expression analysis, The Lancet Oncology, vol.13, issue.6, pp.633-641, 2012.
DOI : 10.1016/S1470-2045(12)70102-X

B. Durie, J. Harousseau, and J. Miguel, International uniform response criteria for multiple myeloma, Leukemia, vol.27, issue.9, pp.1467-1473, 2006.
DOI : 10.1038/sj.leu.2404284

D. Taylor, W. Zacharias, and C. Gercel-taylor, Exosome Isolation for Proteomic Analyses and RNA Profiling, Methods Mol Biol, vol.728, pp.235-246, 2011.
DOI : 10.1007/978-1-61779-068-3_15

M. Kodani, G. Yang, and L. Conklin, Application of TaqMan Low-Density Arrays for Simultaneous Detection of Multiple Respiratory Pathogens, Journal of Clinical Microbiology, vol.49, issue.6, pp.2175-2182, 2011.
DOI : 10.1128/JCM.02270-10

D. 'haene, B. Mestdagh, P. Hellemans, J. Vandesompele, and J. , miRNA expression profiling: from reference genes to global mean normalization, Methods Mol Biol, vol.822, pp.261-272, 2012.

H. Schwarzenbach, N. Nishida, G. Calin, and K. Pantel, Clinical relevance of circulating cell-free microRNAs in cancer, Nature Reviews Clinical Oncology, vol.20, issue.3, pp.145-156, 2014.
DOI : 10.1245/s10434-013-3093-4

L. Kubiczkova, F. Kryukov, and O. Slaby, Circulating serum microRNAs as novel diagnostic and prognostic biomarkers for multiple myeloma and monoclonal gammopathy of undetermined significance, Haematologica, vol.99, issue.3, pp.511-518, 2014.
DOI : 10.3324/haematol.2013.093500

M. Hao, M. Zang, and E. Wendlandt, Low serum miR-19a expression as a novel poor prognostic indicator in multiple myeloma, International Journal of Cancer, vol.434, issue.8, pp.1835-1844, 2015.
DOI : 10.1016/j.bbrc.2013.04.010

A. Rocci, C. Hofmeister, and S. Geyer, Circulating miRNA markers show promise as new prognosticators for multiple myeloma, Leukemia, vol.109, issue.9, pp.1922-1926, 2014.
DOI : 10.1073/pnas.1209414109

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155011

X. Huang, T. Yuan, and M. Liang, Exosomal miR-1290 and miR-375 as Prognostic Markers in Castration-resistant Prostate Cancer, European Urology, vol.67, issue.1, pp.33-41, 2015.
DOI : 10.1016/j.eururo.2014.07.035

S. Melo, L. Luecke, and C. Kahlert, Glypican-1 identifies cancer exosomes and detects early pancreatic cancer, Nature, vol.44, issue.7559, pp.177-182, 2015.
DOI : 10.2307/2531595

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825698

M. Xiang, Y. Zeng, and R. Yang, U6 is not a suitable endogenous control for the quantification of circulating microRNAs, Biochemical and Biophysical Research Communications, vol.454, issue.1, pp.210-214, 2014.
DOI : 10.1016/j.bbrc.2014.10.064

P. Mestdagh, P. Van-vlierberghe, D. Weer, and A. , A novel and universal method for microRNA RT-qPCR data normalization, Genome Biology, vol.10, issue.6, p.64, 2009.
DOI : 10.1186/gb-2009-10-6-r64

URL : https://genomebiology.biomedcentral.com/track/pdf/10.1186/gb-2009-10-6-r64?site=genomebiology.biomedcentral.com

W. Cui, J. Ma, Y. Wang, and S. Biswal, Plasma miRNA as Biomarkers for Assessment of Total-Body Radiation Exposure Dosimetry, PLoS ONE, vol.94, issue.8, p.22988, 2011.
DOI : 10.1371/journal.pone.0022988.s001

S. Roush and F. Slack, The let-7 family of microRNAs, Trends in Cell Biology, vol.18, issue.10, pp.505-516, 2008.
DOI : 10.1016/j.tcb.2008.07.007

S. Manier, J. Powers, and A. Sacco, The LIN28B/ let-7 axis is a novel therapeutic pathway in multiple myeloma [published online ahead of print 11, 2016.

S. Viswanathan, J. Powers, and W. Einhorn, Lin28 promotes transformation and is associated with advanced human malignancies, Nature Genetics, vol.77, issue.7, pp.843-848, 2009.
DOI : 10.1038/nature06866

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757943

A. Jacobsen, J. Silber, G. Harinath, J. Huse, N. Schultz et al., Analysis of microRNA-target interactions across diverse cancer types, Nature Structural & Molecular Biology, vol.2, issue.11, pp.1325-1332, 2013.
DOI : 10.1074/jbc.M707224200

R. Spizzo, M. Nicoloso, C. Croce, and G. Calin, SnapShot: MicroRNAs in Cancer, Cell, vol.137, issue.3, pp.586-586, 2009.
DOI : 10.1016/j.cell.2009.04.040

URL : http://doi.org/10.1016/j.cell.2009.04.040

J. Mendell, miRiad Roles for the miR-17-92 Cluster in Development and Disease, Cell, vol.133, issue.2, pp.217-222, 2008.
DOI : 10.1016/j.cell.2008.04.001

R. Krutilina, W. Sun, and A. Sethuraman, MicroRNA-18a inhibits hypoxia-inducible factor 1?? activity and lung metastasis in basal breast cancers, Breast Cancer Research, vol.4, issue.4, p.78, 2014.
DOI : 10.1016/S1535-6108(03)00194-6

URL : https://breast-cancer-research.biomedcentral.com/track/pdf/10.1186/bcr3693?site=breast-cancer-research.biomedcentral.com

Y. Teng, J. Mu, and X. Hu, Grapefruit-derived nanovectors deliver miR-18a for treatment of liver metastasis of colon cancer by induction of M1 macrophages, Oncotarget, vol.7, issue.18, pp.25683-25697, 2016.
DOI : 10.18632/oncotarget.8361