Lipid droplet hijacking by intracellular pathogens

Abstract : Lipid droplets were long considered to be simple storage structures, but they have recently been shown to be dynamic organelles involved in diverse biological processes, including emerging roles in innate immunity. Various intracellular pathogens, including viruses, bacteria and parasites, specifically target host lipid droplets during their life cycle. Viruses such as hepatitis C virus, dengue virus and rotaviruses use lipid droplets as platforms for assembly. Bacteria, such as mycobacteria and chlamydia, and parasites, such as trypanosomes, use host lipid droplets for nutritional purposes. The possible use of lipid droplets by intracellular pathogens, as part of an anti-immunity strategy, is an intriguing question meriting further investigation in the near future.
Type de document :
Article dans une revue
Cellular Microbiology, Wiley, 2017, 19 (1), e12688 (Epub 2016 Nov 21). 〈10.1016/j.cmet.2011.12.018〉
Liste complète des métadonnées

Littérature citée [77 références]  Voir  Masquer  Télécharger

http://www.hal.inserm.fr/inserm-01575072
Contributeur : Philippe Roingeard <>
Soumis le : jeudi 17 août 2017 - 16:59:43
Dernière modification le : mercredi 21 mars 2018 - 10:54:08

Fichiers

CMI_2017.pdf
Fichiers produits par l'(les) auteur(s)

Identifiants

Collections

Citation

Philippe Roingeard, Rossana Melo. Lipid droplet hijacking by intracellular pathogens. Cellular Microbiology, Wiley, 2017, 19 (1), e12688 (Epub 2016 Nov 21). 〈10.1016/j.cmet.2011.12.018〉. 〈inserm-01575072〉

Partager

Métriques

Consultations de la notice

193

Téléchargements de fichiers

101