Cytogenetic resources and information Running title: Databases for cancer cytogenetics *Corresponding authors

Abstract : The main databases devoted stricto sensu to cancer cytogenetics are the "Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer" ( http://cgap.nci.nih.gov/Chromosomes/Mitelman ), the "Atlas of Genetics and Cytogenetics in Oncology and Haematology" ( http://atlasgeneticsoncology.org ), and COSMIC ( http://cancer.sanger.ac.uk/cosmic ).However, being a complex multistep process, cancer cytogenetics are broadened to "cytogenomics," with complementary resources on: general databases (nucleic acid and protein sequences databases; cartography browsers: GenBank, RefSeq, UCSC, Ensembl, UniProtKB, and Entrez Gene), cancer genomic portals associated with recent international integrated programs, such as TCGA or ICGC, other fusion genes databases, array CGH databases, copy number variation databases, and mutation databases. Other resources such as the International System for Human Cytogenomic Nomenclature (ISCN), the International Classification of Diseases for Oncology (ICD-O), and the Human Gene Nomenclature Database (HGNC) allow a common language.Data within the scientific/medical community should be freely available. However, most of the institutional stakeholders are now gradually disengaging, and well-known databases are forced to beg or to disappear (which may happen!).
Type de document :
Chapitre d'ouvrage
Thomas S.K. Wan. Cancer Cytogenetics - Methods and Protocols, 1541, Springer - Humana Press, 2017, Methods in Molecular Biology, 978-1-4939-6701-8. 〈10.1007/978-1-4939-6703-2_25〉
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Contributeur : Jean-Loup Huret <>
Soumis le : jeudi 16 mars 2017 - 14:41:53
Dernière modification le : mardi 21 mars 2017 - 16:44:24
Document(s) archivé(s) le : samedi 17 juin 2017 - 14:22:52

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H De Braekeleer, Jl Huret, H Mossafa, P Dessen. Cytogenetic resources and information Running title: Databases for cancer cytogenetics *Corresponding authors. Thomas S.K. Wan. Cancer Cytogenetics - Methods and Protocols, 1541, Springer - Humana Press, 2017, Methods in Molecular Biology, 978-1-4939-6701-8. 〈10.1007/978-1-4939-6703-2_25〉. 〈inserm-01491179〉

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