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Article Dans Une Revue Cell Chemical Biology Année : 2016

Eukaryotic Ribosome as a Target for Cardiovascular Disease

Résumé

Cardiovascular diseases have been associated with genetic variants and increased plasma level of the secreted protein PCSK9. In this issue of Cell Chemical Biology, Petersen et al. (2016) describe an inhibitor of PCSK9 secretion in human cells that, surprisingly, targets the 80S ribosome.
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Dates et versions

inserm-01415698 , version 1 (13-12-2016)

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Simone P Pellegrino, Gulnara Yusupova. Eukaryotic Ribosome as a Target for Cardiovascular Disease. Cell Chemical Biology, 2016, 17 (23), pp.1319-1321. ⟨10.1016/j.chembiol.2016.11.004⟩. ⟨inserm-01415698⟩
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