Inhaling medicines: delivering drugs to the body through the lungs, Nature Reviews Drug Discovery, vol.9, issue.1, pp.67-74, 2007. ,
DOI : 10.1038/nrd2153
Amorphous pharmaceutical solids: preparation, characterization and stabilization, Advanced Drug Delivery Reviews, vol.48, issue.1, pp.27-42, 2001. ,
DOI : 10.1016/S0169-409X(01)00098-9
Ideal copolymers and the second-order transitions of synthetic rubbers. i. non-crystalline copolymers, Journal of Applied Chemistry, vol.17, issue.9, pp.493-500, 1952. ,
DOI : 10.1002/jctb.5010020901
Factors affecting short-term and long-term stabilities of proteins, Advanced Drug Delivery Reviews, vol.46, issue.1-3, pp.307-326, 2001. ,
DOI : 10.1016/S0169-409X(00)00144-7
Taking Advantage of Disorder: Amorphous Calcium Carbonate and its Roles in Biomineralization, Adv. Mater, issue.12, pp.15-959, 2003. ,
The Transient Phase of Amorphous Calcium Carbonate in Sea Urchin Larval Spicules: The Involvement of Proteins and Magnesium Ions in Its Formation and Stabilization, Advanced Functional Materials, vol.13, issue.6, pp.13-480, 2003. ,
DOI : 10.1002/adfm.200304285
Thermophysical Investigations of the Polymorphous Phases of Calcium Carbonate, Journal of Thermal Analysis and Calorimetry, vol.65, issue.3, pp.687-698, 2001. ,
DOI : 10.1023/A:1011991124181
Microwave Hydrothermal Transformation of Amorphous Calcium Carbonate Nanospheres and Application in Protein Adsorption, ACS Applied Materials & Interfaces, vol.6, issue.6, pp.4310-4320 ,
DOI : 10.1021/am4060645
Factors Involved in the Formation of Amorphous and Crystalline Calcium Carbonate:?? A Study of an Ascidian Skeleton, Journal of the American Chemical Society, vol.124, issue.1, pp.32-39, 2002. ,
DOI : 10.1021/ja016990l
Coexistence of Amorphous and Crystalline Calcium Carbonate in Skeletal Tissues, Connective Tissue Research, vol.9, issue.1, pp.20-25, 2003. ,
DOI : 10.1021/ja00078a005
Sea Urchin Spine Calcite Forms via a Transient Amorphous Calcium Carbonate Phase, Science, vol.306, issue.5699, pp.306-1161, 2004. ,
DOI : 10.1126/science.1102289
Crustacean-Derived Biomimetic Components and Nanostructured Composites, Small, vol.102, issue.16, pp.3207-3232 ,
DOI : 10.1002/smll.201400559
Formation of Transient Amorphous Calcium Carbonate Precursor in Quail Eggshell Mineralization: an In Vitro Study, Biomacromolecules, vol.7, issue.11, pp.3202-3209, 2006. ,
Amorphous calcium phosphate is a major component of the forming fin bones of zebrafish: Indications for an amorphous precursor phase, Proceedings of the National Academy of Sciences, vol.105, issue.35, pp.105-12748, 2008. ,
DOI : 10.1073/pnas.0803354105
Stabilization of amorphous calcium carbonate by phosphate rich organic matrix proteins and by single phosphoamino acids, Journal of Structural Biology, vol.171, issue.2, pp.171-207, 2010. ,
DOI : 10.1016/j.jsb.2010.04.007
The Initial Stages of Template-Controlled CaCO3 Formation Revealed by Cryo-TEM, Science, vol.323, issue.5920, pp.323-1455, 2009. ,
DOI : 10.1126/science.1169434
Transformation Mechanism of Amorphous Calcium Carbonate into Calcite in the Sea Urchin Larval Spicule, Proc. Natl. Acad. Sci. U. S. A, issue.50, pp.105-20045, 2008. ,
Transformation and crystallization energetics of synthetic and biogenic amorphous calcium carbonate, Proceedings of the National Academy of Sciences, vol.107, issue.38, pp.107-16438, 2010. ,
DOI : 10.1073/pnas.1009959107
Stabilization of Amorphous Calcium Carbonate with Nanofibrillar Biopolymers, Advanced Functional Materials, vol.15, issue.16, pp.22-3460 ,
DOI : 10.1002/adfm.201103144
Polysaccharides and Proteoglycans in Calcium Carbonate-based Biomineralization, Chemical Reviews, vol.108, issue.11, pp.4475-4482, 2008. ,
DOI : 10.1021/cr078269p
Hyaluronic Acid Improves the Tolerability of Hypertonic Saline in the Chronic Treatment of Cystic Fibrosis Patients: A Multicenter, Randomized, Controlled Clinical Trial, J. Aerosol Med. Pulm. Drug Delivery, vol.2014, issue.272, pp.133-137 ,
Inhaled Alpha 1-Antitrypsin: Gauging Patient Interest in a New Treatment, COPD: Journal of Chronic Obstructive Pulmonary Disease, vol.23, issue.1, pp.411-415 ,
DOI : 10.1001/jama.1988.03720190058032
Heterogeneous uptake and reactivity of formic acid on calcium carbonate particles: a Knudsen cell reactor, FTIR and SEM study, Physical Chemistry Chemical Physics, vol.64, issue.20, pp.7-3587, 2005. ,
DOI : 10.1029/2004JD005206
Quantitative analysis of synthetic calcium carbonate polymorphs using FT-IR spectroscopy, Talanta, vol.59, issue.4, pp.831-836, 2003. ,
DOI : 10.1016/S0039-9140(02)00638-0
Biogenic Fish-gut Calcium Carbonate is a Stable Amorphous Phase in the Gilt-head Seabream, Sparus aurata, Scientific Reports, vol.18, pp.1-5, 2013. ,
DOI : 10.1038/srep01700
Dehydration and crystallization of amorphous calcium carbonate in solution and in air, Nature Communications, vol.179, issue.564, pp.2014-2015 ,
DOI : 10.1038/ncomms4169
Formate incorporation in the structure of Ca-deficient apatite: Rietveld structure refinement, Journal of Solid State Chemistry, vol.174, issue.1, pp.132-140, 2003. ,
DOI : 10.1016/S0022-4596(03)00188-9
Wettability and surface chemistry of crystalline and amorphous forms of a poorly water soluble drug, European Journal of Pharmaceutical Sciences, vol.40, issue.2, pp.40-84, 2010. ,
DOI : 10.1016/j.ejps.2010.03.003
Evaluation of HP??CD???PEG Microparticles for Salmon Calcitonin Administration via Pulmonary Delivery, Molecular Pharmaceutics, vol.8, issue.5, pp.1887-1898, 2011. ,
DOI : 10.1021/mp200231c
Development and characterisation of soluble polymeric particles for pulmonary peptide delivery, European Journal of Pharmaceutical Sciences, vol.41, issue.2, pp.41-337, 2010. ,
DOI : 10.1016/j.ejps.2010.07.001
URL : https://hal.archives-ouvertes.fr/inserm-01102826
Calcium carbonate crystallization in the presence of modified polysaccharides and linear polymeric additives, Journal of Crystal Growth, vol.310, issue.21, pp.310-4561, 2008. ,
DOI : 10.1016/j.jcrysgro.2008.07.089
Biomimetic nucleation and growth of hydrophobic vaterite nanoparticles with oleic acid in a methanol solution, Applied Surface Science, vol.253, issue.10, pp.253-4768, 2007. ,
DOI : 10.1016/j.apsusc.2006.10.048
Dehydration-Induced Amorphous Phases of Calcium Carbonate, The Journal of Physical Chemistry B, vol.117, issue.12, pp.117-3328 ,
DOI : 10.1021/jp308353t
Composite Nanoparticles Based on Hyaluronic Acid Chemically Cross-Linked with ??,??-Polyaspartylhydrazide, Biomacromolecules, vol.8, issue.6, pp.1890-1898, 2007. ,
DOI : 10.1021/bm070224a
Oral delivery of salmon calcitonin, Advanced Drug Delivery Reviews, vol.42, issue.3, pp.225-238, 2000. ,
DOI : 10.1016/S0169-409X(00)00063-6
Particle formation in spray drying, Journal of Aerosol Science, vol.38, issue.7, pp.728-746, 2007. ,
DOI : 10.1016/j.jaerosci.2007.04.005
Stabilization of amorphous calcium carbonate by specialized macromolecules in biological and synthetic precipitates, Advanced Materials, vol.73, issue.3, pp.222-226, 1996. ,
DOI : 10.1002/adma.19960080307
Water Is the Key to Nonclassical Nucleation of Amorphous Calcium Carbonate, Journal of the American Chemical Society, vol.132, issue.49, pp.132-17623, 2010. ,
DOI : 10.1021/ja108508k
Onset of Orientational Order in Amorphous Calcium Carbonate (ACC) upon Dehydration, Chemical Physics Letters, vol.591, issue.0, pp.591-287 ,
DOI : 10.1016/j.cplett.2013.11.020
The kinetics and mechanisms of amorphous calcium carbonate (ACC) crystallization to calcite, viavaterite., Nanoscale, vol.290, issue.129, pp.265-271, 2011. ,
DOI : 10.1021/cg100631v
The rate and mechanism of polymorphic transformation of calcium carbonate in water, Journal of Crystal Growth, vol.100, issue.1-2, pp.159-167, 1990. ,
DOI : 10.1016/0022-0248(90)90618-U
Binding of Ethanol on Calcite: The Role of the OH Bond and Its Relevance to Biomineralization, Langmuir, vol.26, issue.19, pp.26-15239, 2010. ,
DOI : 10.1021/la101136j
Freeze-drying yields stable and pure amorphous calcium carbonate (ACC), Chemical Communications, vol.105, issue.30, pp.49-3134 ,
DOI : 10.1002/adfm.201201805
Trends in Solubility of Polymorphs, Journal of Pharmaceutical Sciences, vol.94, issue.5, pp.929-939, 2005. ,
DOI : 10.1002/jps.20302
Calcium Carbonate Crystallization in the Presence of Biopolymers, Crystal Growth & Design, vol.6, issue.3, pp.781-794, 2006. ,
DOI : 10.1021/cg050436w
Switching between kinetic and thermodynamic control: calcium carbonate growth in the presence of a simple alcohol, Journal of Materials Chemistry, vol.13, issue.4, pp.928-933, 2003. ,
DOI : 10.1039/b208741n
Controlling the kinetic versus thermodynamic crystallisation of calcium carbonate, Journal of Crystal Growth, vol.244, issue.3-4, pp.3-4, 2002. ,
DOI : 10.1016/S0022-0248(02)01700-1
Influence of Particle Size on Regional Lung Deposition ? What Evidence is there? Int, J. Pharm, vol.406, issue.12, pp.1-10, 2011. ,
Dry powders for oral inhalation free of lactose carrier particles, Advanced Drug Delivery Reviews, vol.75, pp.32-52, 2014. ,
DOI : 10.1016/j.addr.2014.04.005
Particle Size Analysis in Pharmaceutics: Principles, Methods and Applications, Pharmaceutical Research, vol.19, issue.199, pp.203-227, 2007. ,
DOI : 10.1007/s11095-006-9146-7
Particle Morphology and Density Characterization by Combined Mobility and Aerodynamic Diameter Measurements. Part 1: Theory, Aerosol Sci. Technol, issue.12, pp.38-1185, 2004. ,
Trojan particles: Large porous carriers of nanoparticles for drug delivery, Proceedings of the National Academy of Sciences, vol.99, issue.19, pp.99-12001, 2002. ,
DOI : 10.1073/pnas.182233999
Mucokinetic Hybrid Nanoporous Microparticles for Pulmonary Drug Delivery ,
Optimisation of spray drying process conditions for sugar nanoporous microparticles (NPMPs) intended for inhalation, International Journal of Pharmaceutics, vol.421, issue.1, pp.99-109, 2011. ,
DOI : 10.1016/j.ijpharm.2011.09.021
Physical Stability of Salmon Calcitonin Spray?Dried Powders for Inhalation, J. Pharm. Sci, vol.93, issue.3, pp.792-804, 2004. ,
Protein-Calcium Carbonate Coprecipitation: A Tool for Protein Encapsulation, Biotechnology Progress, vol.16, issue.1, pp.918-943, 2005. ,
DOI : 10.1021/bp0495825
Lysozyme Encapsulation into Nanostructured CaCO 3 Microparticles Using a Supercritical CO 2 Process and Comparison with the Normal Route, J. Mater. Chem. B, vol.2013, issue.132, pp.4011-4019 ,
Lung protease/anti-protease network and modulation of mucus production and surfactant activity, Biochimie, vol.92, issue.11, pp.92-1608, 2010. ,
DOI : 10.1016/j.biochi.2010.05.010
Improved intrapulmonary delivery of site-specific PEGylated salmon calcitonin: Optimization by PEG size selection, Journal of Controlled Release, vol.125, issue.1, pp.68-75, 2008. ,
DOI : 10.1016/j.jconrel.2007.10.008