Allergen immunotherapy for allergic asthma: protocol for a systematic review.

Sangeeta Dhami 1, * Ulugbek Nurmatov 2 Ioana Agache 3 Susanne Lau 4 Antonella Muraro 5 Marek Jutel 6 Graham Roberts 7, 8 Cezmi Akdis 9 Matteo Bonini 10 Moises Calderon 11 Thomas Casale 12 Ozlem Cavkaytar 13 Linda Cox 1, 14 Pascal Demoly 15 Breda Flood 16 Eckard Hamelmann 17, 18 Kenji Izuhara 19 Ömer Kalayci 20 Jörg Kleine-Tebbe 21 Antonio Nieto 22 Nikolaos Papadopoulos 23 Oliver Pfaar 24, 25 Lanny Rosenwasser 26 Dermot Ryan 27 Carsten Schmidt-Weber 28, 29 Stan Szefler 30 Ulrich Wahn 31 Roy-Gerth Van Wijk 32 Jamie Wilkinson 33 Aziz Sheikh 34
Abstract : Background. The European Academy of Allergy and Clinical Immunology (EAACI) is in the process of developing the EAACI Guidelines for Allergen Immunotherapy (AIT) for Allergic Asthma. We seek to critically assess the effectiveness, cost-effectiveness and safety of AIT in the management of allergic asthma. Methods. We will undertake a systematic review, which will involve searching international biomedical databases for published, in progress and unpublished evidence. Studies will be independently screened against pre-defined eligibility criteria and critically appraised using established instruments. Data will be descriptively and, if possible and appropriate, quantitatively synthesised. Discussion. The findings from this review will be used to inform the development of recommendations for EAACI’s Guidelines on AIT.
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Clinical and Translational Allergy, BioMed Central, 2016, 6 (1), pp.5. 〈10.1186/s13601-016-0094-y〉
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Sangeeta Dhami, Ulugbek Nurmatov, Ioana Agache, Susanne Lau, Antonella Muraro, et al.. Allergen immunotherapy for allergic asthma: protocol for a systematic review.. Clinical and Translational Allergy, BioMed Central, 2016, 6 (1), pp.5. 〈10.1186/s13601-016-0094-y〉. 〈inserm-01322498〉

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