P. Jain, O. Brien, and S. , Anti-CD20 monoclonal antibodies in chronic lymphocytic leukemia, Expert Opinion on Biological Therapy, vol.96, issue.2, pp.169-182, 2013.
DOI : 10.1038/leu.2008.214

K. Meadows and H. Hurwitz, Anti-VEGF Therapies in the Clinic, Cold Spring Harbor Perspectives in Medicine, vol.2, issue.10, 2012.
DOI : 10.1101/cshperspect.a006577

S. Lim and R. Levy, Translational Medicine in Action: Anti-CD20 Therapy in Lymphoma, The Journal of Immunology, vol.193, issue.4, pp.1519-1524, 1950.
DOI : 10.4049/jimmunol.1490027

J. Wolchok, H. Kluger, M. Callahan, M. Postow, N. Rizvi et al., Nivolumab plus Ipilimumab in Advanced Melanoma, New England Journal of Medicine, vol.369, issue.2, pp.122-133, 2013.
DOI : 10.1056/NEJMoa1302369

J. Weber, D. Angelo, S. Minor, D. Hodi, F. Gutzmer et al., Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial, The Lancet Oncology, vol.16, issue.4, pp.375-384, 2015.
DOI : 10.1016/S1470-2045(15)70076-8

K. Palucka and J. Banchereau, Cancer immunotherapy via dendritic cells, Nature Reviews Cancer, vol.29, issue.4, pp.265-277, 2012.
DOI : 10.1038/nrc3258

G. Zom, S. Khan, C. Britten, V. Sommandas, M. Camps et al., Efficient Induction of Antitumor Immunity by Synthetic Toll-like Receptor Ligand-Peptide Conjugates, Cancer Immunology Research, vol.2, issue.8, pp.756-764, 2014.
DOI : 10.1158/2326-6066.CIR-13-0223

D. Porter, W. Hwang, N. Frey, S. Lacey, P. Shaw et al., Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia, Science Translational Medicine, vol.7, issue.303, pp.303-139, 2015.
DOI : 10.1126/scitranslmed.aac5415

S. Kakarla and S. Gottschalk, CAR T Cells for Solid Tumors, The Cancer Journal, vol.20, issue.2, pp.151-155, 2014.
DOI : 10.1097/PPO.0000000000000032

A. Tarhini, H. Gogas, and J. Kirkwood, IFN-? in the treatment of melanoma, J. Immunol. Baltim. Md, vol.189, pp.3789-3793, 1950.

R. Gupta and L. Emens, GM-CSF-secreting vaccines for solid tumors: moving forward, Discov. Med, vol.10, pp.52-60, 2010.

T. Mckeithan, Kinetic proofreading in T-cell receptor signal transduction., Proceedings of the National Academy of Sciences, vol.92, issue.11, pp.5042-5048, 1995.
DOI : 10.1073/pnas.92.11.5042

K. Tkach, D. Barik, G. Voisinne, N. Malandro, M. Hathorn et al., Altan-Bonnet G. T cells translate individual, quantal activation into collective, analog cytokine responses via time-integrated feedbacks, eLife, vol.3, p.1944, 2014.

C. Conche, G. Boulla, A. Trautmann, and C. Randriamampita, T Cell Adhesion Primes Antigen Receptor-Induced Calcium Responses through a Transient Rise in Adenosine 3???,5???-Cyclic Monophosphate, Immunity, vol.30, issue.1, pp.33-43, 2009.
DOI : 10.1016/j.immuni.2008.10.020

L. Goentoro, O. Shoval, M. Kirschner, and U. Alon, The Incoherent Feedforward Loop Can Provide Fold-Change Detection in Gene Regulation, Molecular Cell, vol.36, issue.5, pp.894-899, 2009.
DOI : 10.1016/j.molcel.2009.11.018

T. Pradeu and E. Carosella, On the definition of a criterion of immunogenicity, Proceedings of the National Academy of Sciences, vol.103, issue.47, pp.17858-61, 2006.
DOI : 10.1073/pnas.0608683103
URL : https://hal.archives-ouvertes.fr/halshs-00790957

T. Pradeu, S. Jaeger, and E. Vivier, The speed of change: towards a discontinuity theory of immunity?, Nature Reviews Immunology, vol.4, issue.10, pp.764-769, 2013.
DOI : 10.1038/nri3521
URL : https://hal.archives-ouvertes.fr/hal-01343694

G. Litman, M. Anderson, and J. Rast, EVOLUTION OF ANTIGEN BINDING RECEPTORS, Annual Review of Immunology, vol.17, issue.1, pp.109-147, 1999.
DOI : 10.1146/annurev.immunol.17.1.109

J. Pollard, Trophic macrophages in development and disease, Nature Reviews Immunology, vol.87, issue.4, pp.259-70, 2009.
DOI : 10.1038/nri2528

G. Eberl, A new vision of immunity: homeostasis of the superorganism, Mucosal Immunology, vol.41, issue.5, pp.450-460, 2010.
DOI : 10.1016/j.immuni.2008.05.009
URL : https://hal.archives-ouvertes.fr/pasteur-00509637

P. Sansonetti, War and peace at mucosal surfaces, Nature Reviews Immunology, vol.67, issue.12, pp.953-964, 2004.
DOI : 10.1016/j.it.2003.10.007

M. Colonna, G. Trinchieri, and Y. Liu, Plasmacytoid dendritic cells in immunity, Nature Immunology, vol.165, issue.12, pp.1219-1245, 2004.
DOI : 10.1038/32588

N. Kamada, G. Chen, N. Inohara, and G. Núñez, Control of pathogens and pathobionts by the gut microbiota, Nature Immunology, vol.86, issue.7, pp.685-690, 2013.
DOI : 10.1084/jem.20120504

J. Miller, R. Van-der-most, R. Akondy, J. Glidewell, S. Albott et al., Human Effector and Memory CD8+ T Cell Responses to??Smallpox and Yellow Fever Vaccines, Immunity, vol.28, issue.5, pp.710-732, 2008.
DOI : 10.1016/j.immuni.2008.02.020

D. Sojka, D. Bruniquel, R. Schwartz, and N. Singh, IL-2 Secretion by CD4+ T Cells In Vivo Is Rapid, Transient, and Influenced by TCR-Specific Competition, The Journal of Immunology, vol.172, issue.10, pp.6136-6179, 2004.
DOI : 10.4049/jimmunol.172.10.6136

M. Isogawa, Y. Furuichi, and F. Chisari, Oscillating CD8+ T Cell Effector Functions after Antigen Recognition in the Liver, Immunity, vol.23, issue.1, pp.53-63, 2005.
DOI : 10.1016/j.immuni.2005.05.005

B. Fife and J. Bluestone, Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways, Immunological Reviews, vol.113, issue.(Suppl.), pp.166-182, 2008.
DOI : 10.1111/j.1600-065X.2008.00662.x

S. Wang, S. Fouquet, M. Chapon, H. Salmon, F. Regnier et al., Early T Cell Signalling Is Reversibly Altered in PD-1+ T Lymphocytes Infiltrating Human Tumors, PLoS ONE, vol.204, issue.3, p.17621, 2011.
DOI : 10.1371/journal.pone.0017621.s006

Z. Zhao, F. Granucci, L. Yeh, P. Schaffer, and H. Cantor, Molecular Mimicry by Herpes Simplex Virus-Type 1: Autoimmune Disease After Viral Infection, Science, vol.279, issue.5355, pp.1344-1347, 1998.
DOI : 10.1126/science.279.5355.1344

C. Buckley, D. Pilling, J. Lord, A. Akbar, D. Scheel-toellner et al., Fibroblasts regulate the switch from acute resolving to chronic persistent inflammation, Trends in Immunology, vol.22, issue.4, pp.199-204, 2001.
DOI : 10.1016/S1471-4906(01)01863-4

M. Bissell and W. Hines, Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression, Nature Medicine, vol.23, issue.3, pp.320-329, 2011.
DOI : 10.1038/nm.2328

N. Erez, M. Truitt, P. Olson, S. Arron, and D. Hanahan, Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-??B-Dependent Manner, Cancer Cell, vol.17, issue.2, pp.135-182, 2010.
DOI : 10.1016/j.ccr.2009.12.041

J. Eyles, A. Puaux, X. Wang, B. Toh, C. Prakash et al., Tumor cells disseminate early, but immunosurveillance limits metastatic outgrowth, in a mouse model of melanoma, Journal of Clinical Investigation, vol.120, issue.6, pp.2030-2039, 2010.
DOI : 10.1172/JCI42002DS1

R. Medzhitov, Origin and physiological roles of inflammation, Nature, vol.21, issue.7203, pp.428-463, 2008.
DOI : 10.1038/nature07201

R. Goldszmid and G. Trinchieri, The price of immunity, Nature Immunology, vol.90, issue.10, pp.932-938, 2012.
DOI : 10.1126/science.2996144

L. Coussens and Z. Werb, Inflammation and cancer, Nature, vol.2, issue.6917, pp.860-867, 2002.
DOI : 10.1006/cyto.1996.0074

A. Mantovani, S. Sozzani, M. Locati, P. Allavena, and A. Sica, Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes, Trends in Immunology, vol.23, issue.11, pp.549-55, 2002.
DOI : 10.1016/S1471-4906(02)02302-5

N. Affara, B. Ruffell, T. Medler, A. Gunderson, M. Johansson et al., B Cells Regulate Macrophage Phenotype and Response to Chemotherapy in Squamous Carcinomas, Cancer Cell, vol.25, issue.6, pp.809-821, 2014.
DOI : 10.1016/j.ccr.2014.04.026

J. Xue, S. Schmidt, J. Sander, A. Draffehn, W. Krebs et al., Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation, Immunity, vol.40, issue.2, pp.274-288, 2014.
DOI : 10.1016/j.immuni.2014.01.006

A. Mantovani and P. Allavena, The interaction of anticancer therapies with tumor-associated macrophages, The Journal of Experimental Medicine, vol.14, issue.4, pp.435-445, 2015.
DOI : 10.1158/1078-0432.CCR-10-1343

H. Cann, S. Van-netten, J. Van-netten, and C. , Dr William Coley and tumour regression: a place in history or in the future, Postgrad Med J, vol.79, pp.672-80, 2003.

B. Wiemann and C. Starnes, Coley's toxins, tumor necrosis factor and cancer research: A historical perspective, Pharmacology & Therapeutics, vol.64, issue.3, pp.529-564, 1994.
DOI : 10.1016/0163-7258(94)90023-X

N. Gandhi, A. Morales, and D. Lamm, Bacillus Calmette-Gu??rin immunotherapy for genitourinary cancer, BJU International, vol.187, issue.3
DOI : 10.1111/j.1464-410X.2012.11754.x

S. Russell, K. Peng, and J. Bell, Oncolytic virotherapy, Nature Biotechnology, vol.311, issue.7, pp.658-70, 2012.
DOI : 10.1038/nbt.2287

S. Rosenberg, Y. Zhai, J. Yang, D. Schwartzentruber, P. Hwu et al., Immunizing Patients With Metastatic Melanoma Using Recombinant Adenoviruses Encoding MART-1 or gp100 Melanoma Antigens, JNCI Journal of the National Cancer Institute, vol.90, issue.24, pp.1894-1900, 1998.
DOI : 10.1093/jnci/90.24.1894

M. Thoreau, H. Penny, K. Tan, F. Regnier, J. Weiss et al., Vaccine-induced tumor regression requires a dynamic cooperation between T cells and myeloid cells at the tumor site, Oncotarget, vol.6, issue.29, pp.27832-27846, 2015.
DOI : 10.18632/oncotarget.4940
URL : https://hal.archives-ouvertes.fr/inserm-01214610

N. Bercovici and A. Trautmann, Revisiting the role of T cells in tumor regression, OncoImmunology, vol.79, issue.3, pp.346-350, 2012.
DOI : 10.1002/ijc.24961

M. Thoreau, Vaccine-induced tumor regression requires a dynamic cooperation between T cells and myeloid cells at the tumor site, Oncotarget, vol.6, issue.29
DOI : 10.18632/oncotarget.4940
URL : https://hal.archives-ouvertes.fr/inserm-01214610

R. Morgan, N. Chinnasamy, D. Abate-daga, A. Gros, P. Robbins et al., Cancer Regression and Neurological Toxicity Following Anti-MAGE-A3 TCR Gene Therapy, Journal of Immunotherapy, vol.36, issue.2, pp.133-151, 1997.
DOI : 10.1097/CJI.0b013e3182829903

K. Rajani, C. Parrish, T. Kottke, J. Thompson, S. Zaidi et al., Combination Therapy With Reovirus and Anti-PD-1 Blockade Controls Tumor Growth Through Innate and Adaptive Immune Responses, Molecular Therapy, vol.24, issue.1, pp.166-174, 2016.
DOI : 10.1038/mt.2015.156

T. Hoshi, W. Zagotta, and R. Aldrich, Biophysical and molecular mechanisms of Shaker potassium channel inactivation, Science, vol.250, issue.4980, pp.533-538, 1990.
DOI : 10.1126/science.2122519

B. Katz and S. Thesleff, A study of the ???desensitization??? produced by acetylcholine at the motor end-plate, The Journal of Physiology, vol.138, issue.1, pp.63-80, 1957.
DOI : 10.1113/jphysiol.1957.sp005838