R. P. Rösch and . Baum, Generator-based PET radiopharmaceuticals for molecular imaging of tumours: on the way to THERANOSTICS, Dalton Transactions, vol.68, issue.23, pp.6104-6111, 2011.
DOI : 10.1039/c0dt01504k

L. Kolsky, V. Joshi, L. F. Mausner, and S. C. Srivastava, Radiochemical purification of no-carrier-added scandium-47 for radioimmunotherapy, Applied Radiation and Isotopes, vol.49, issue.12, pp.1541-1549, 1998.
DOI : 10.1016/S0969-8043(98)00016-5

A. Polosak, S. Kasperek, A. Krajewski, and . Bilewicz, Stability of 47Sc-complexes with acyclic polyamino-polycarboxylate ligands, Journal of Radioanalytical and Nuclear Chemistry, vol.64, issue.3, pp.1867-1872, 2013.
DOI : 10.1007/s10967-012-2188-x

M. Müller, S. Bunka, U. Haller, V. Köster, P. Groehn et al., Promising Prospects for 44Sc-/47Sc-Based Theragnostics: Application of 47Sc for Radionuclide Tumor Therapy in Mice, Journal of Nuclear Medicine, vol.55, issue.10, pp.1658-1664, 2014.
DOI : 10.2967/jnumed.114.141614

F. Mamtimin, V. N. Harmon, and . Starovoitova, Sc-47 production from titanium targets using electron linacs, Applied Radiation and Isotopes, vol.102, pp.1-4, 2015.
DOI : 10.1016/j.apradiso.2015.04.012

J. Grignon, M. Barbet, T. Bardiès, J. F. Carlier, O. Chatal et al., Nuclear medical imaging using ??+?? coincidences from 44Sc radio-nuclide with liquid xenon as detection medium, Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, vol.571, issue.1-2, pp.142-145, 2007.
DOI : 10.1016/j.nima.2006.10.048
URL : https://hal.archives-ouvertes.fr/in2p3-00145475

I. Krajewski, K. Cydzik, A. Abbas, F. Bulgheroni, U. Simonelli et al., Sc for clinical application, Radiochimica Acta, vol.101, issue.5, pp.333-338, 2013.
DOI : 10.1524/ract.2013.2032

R. Alliot, N. Kerdjoudj, F. Michel, S. Haddad, and . Huclier-markai, Cyclotron production of high purity 44m,44 Sc with deuterons from 44 CaCO 3 targets, Nuclear Medicine and Biology, vol.42, issue.6, pp.524-529, 2015.
DOI : 10.1016/j.nucmedbio.2015.03.002
URL : https://hal.archives-ouvertes.fr/hal-01201681

S. M. Bostan and . Qaim, induced by 6 to 13 MeV neutrons, Physical Review C, vol.49, issue.1, pp.266-271, 1994.
DOI : 10.1103/PhysRevC.49.266

D. Bartholomä, Recent developments in the design of bifunctional chelators for metal-based radiopharmaceuticals used in Positron Emission Tomography, Inorganica Chimica Acta, vol.389, pp.36-51, 2012.
DOI : 10.1016/j.ica.2012.01.061

D. W. Carroll, T. J. Demoin, S. S. Hoffman, and . Jurisson, Inorganic chemistry in nuclear imaging and radiotherapy: current and future directions, Radiochimica Acta, vol.100, issue.8-9, pp.653-667, 2012.
DOI : 10.1524/ract.2012.1964

S. Cutler, H. M. Hennkens, N. Sisay, S. Huclier-markai, and S. S. Jurisson, Radiometals for Combined Imaging and Therapy, Chemical Reviews, vol.113, issue.2, pp.858-883, 2013.
DOI : 10.1021/cr3003104
URL : https://hal.archives-ouvertes.fr/in2p3-00858352

F. Ramogida and C. Orvig, Tumour targeting with radiometals for diagnosis and therapy, Chemical Communications, vol.128, issue.suppl. 1, pp.4720-4739, 2013.
DOI : 10.1039/c3cc41554f

I. Krajewski, K. Cydzik, A. Abbas, F. Bulgheroni, U. Simonelli et al., Sc for clinical application, Radiochimica Acta, vol.101, issue.5, pp.333-338, 2013.
DOI : 10.1524/ract.2013.2032

A. Majkowska-pilip and . Bilewicz, Macrocyclic complexes of scandium radionuclides as precursors for diagnostic and therapeutic radiopharmaceuticals, Journal of Inorganic Biochemistry, vol.105, issue.2, pp.313-320, 2011.
DOI : 10.1016/j.jinorgbio.2010.11.003

A. Pruszy?ski, N. S. Majkowska-pilip, E. Loktionova, F. Eppard, and . Rösch, Radiolabeling of DOTATOC with the long-lived positron emitter 44Sc, Applied Radiation and Isotopes, vol.70, issue.6, pp.974-979, 2012.
DOI : 10.1016/j.apradiso.2012.03.005

N. S. Koumarianou, M. Loktionova, F. Fellner, O. Rösch, D. Thews et al., 44Sc-DOTA-BN[2-14]NH2 in comparison to 68Ga-DOTA-BN[2-14]NH2 in pre-clinical investigation. Is 44Sc a potential radionuclide for PET?, Applied Radiation and Isotopes, vol.70, issue.12, pp.2669-2676, 2012.
DOI : 10.1016/j.apradiso.2012.08.004

A. R. Moghaddam-banaem, M. R. Jalilian, E. Pourjavid, A. Radfar, K. Bahrami-samani et al., Development of a??radioscandium immunoconjugate for radioimmunotherapy, Radiochimica Acta, vol.100, issue.3, pp.215-221, 2012.
DOI : 10.1524/ract.2012.1902

S. Chakravarty, H. F. Goel, R. Valdovinos, H. Hernandez, R. J. Hong et al., Sc-Labeled Cetuximab Fab Fragment, Bioconjugate Chemistry, vol.25, issue.12, pp.2197-2204, 2014.
DOI : 10.1021/bc500415x

D. R. Eigner, M. Beckford-vera, N. S. Fellner, M. Loktionova, O. Piel et al., Imaging of Protein Synthesis: In Vitro and In Vivo Evaluation of 44Sc-DOTA-Puromycin, Molecular Imaging and Biology, vol.45, issue.2, pp.79-86, 2013.
DOI : 10.1007/s11307-012-0561-3

M. Müller, J. Bunka, C. Reber, K. Fischer, A. Zhernosekov et al., Promises of Cyclotron-Produced 44Sc as a Diagnostic Match for Trivalent ??--Emitters: In Vitro and In Vivo Study of a 44Sc-DOTA-Folate Conjugate, Journal of Nuclear Medicine, vol.54, issue.12, pp.2168-2174, 2013.
DOI : 10.2967/jnumed.113.123810

V. Pniok, J. Kubí?ek, J. Havlí?ková, A. Kotek, J. Sabatie-gogová et al., Thermodynamic and Kinetic Study of Scandium(III) Complexes of DTPA and DOTA: A Step Toward Scandium Radiopharmaceuticals, Chemistry - A European Journal, vol.51, issue.26, pp.7944-7955, 2014.
DOI : 10.1002/chem.201402041
URL : https://hal.archives-ouvertes.fr/in2p3-01070048

P. Táborský, J. Lubal, J. Havel, P. Kotek, I. Hermann et al., Thermodynamic and Kinetic Studies of Lanthanide(III) Complexes with H5do3ap (1,4,7,10-Tetraazacyclododecane-1,4,7-triacetic-10-(methylphosphonic Acid)), a Monophosphonate Analogue of H4dota, Collection of Czechoslovak Chemical Communications, vol.70, issue.11, pp.1909-1942, 2005.
DOI : 10.1135/cccc20051909

. Open-access-article, 43:22. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence, pp.4119-4130, 2007.

M. Försterová, A. Pet?ík, M. Lázni?ková, P. Lázní?ek, I. Hermann et al., Complexation and biodistribution study of 111In and 90Y complexes of bifunctional phosphinic acid analogs of H4dota, Applied Radiation and Isotopes, vol.67, issue.1, pp.21-29, 2009.
DOI : 10.1016/j.apradiso.2008.08.013

F. Lacerda, P. Marques, L. Campello, V. Gano, P. Kubí?ek et al., Chemical, radiochemical and biological studies of Sm and Ho complexes of H4dota analogues containing one methylphosphonic/phosphinic acid pendant arm, Journal of Labelled Compounds and Radiopharmaceuticals, vol.26, issue.1, pp.36-43, 2010.
DOI : 10.1002/jlcr.1697

P. ?ime?ek, J. Hermann, E. Havlí?ková, T. G. Herdtweck, N. Kapp et al., A Cyclen-Based Tetraphosphinate Chelator for the Preparation of Radiolabeled Tetrameric Bioconjugates, Chemistry - A European Journal, vol.39, issue.24, pp.7748-7757, 2013.
DOI : 10.1002/chem.201300338

P. Notni, J. Hermann, J. Havlí?ková, V. Kotek, J. Kubí?ek et al., Ga Tracers for Positron Emission Tomography, Chemistry - A European Journal, vol.13, issue.217, pp.7174-7185, 2010.
DOI : 10.1002/chem.200903281

J. Notni, H. ?ime?ek, and . Wester, Phosphinic Acid Functionalized Polyazacycloalkane Chelators for Radiodiagnostics and Radiotherapeutics: Unique Characteristics and Applications, ChemMedChem, vol.2, issue.6, pp.1107-1115, 2014.
DOI : 10.1002/cmdc.201400055

J. Rudovský, P. Kotek, I. Hermann, V. Luke?, S. Mainero et al., ) complex endowed with an optimal water exchange rate for MRI applications, Org. Biomol. Chem., vol.39, issue.1, pp.112-117, 2005.
DOI : 10.1039/B410103K

J. Kubí?ek, J. Havlí?ková, G. Kotek, P. Tircsó, É. Hermann et al., Gallium(III) Complexes of DOTA and DOTA???Monoamide: Kinetic and Thermodynamic Studies, Inorganic Chemistry, vol.49, issue.23, pp.10960-10969, 2010.
DOI : 10.1021/ic101378s

I. Kývala and . Luke?, Full version of the OPIUM program package is available at http, Abstract book, p.63, 1995.

A. Kirakosyan, V. P. Tarasov, and Y. A. Buslaev, 45Sc NMR study of scandium complex formation in non-aqueous solutions, Magnetic Resonance in Chemistry, vol.33, issue.2, pp.103-111, 1989.
DOI : 10.1002/mrc.1260270202

G. Benetollo, L. Bombieri, S. Calabi, M. Aime, and . Botta, Structural Variations Across the Lanthanide Series of Macrocyclic DOTA Complexes:?? Insights into the Design of Contrast Agents for Magnetic Resonance Imaging, Inorganic Chemistry, vol.42, issue.1, pp.148-157, 2003.
DOI : 10.1021/ic025790n

L. Nash, F-Element complexation by diphosphonate ligands, Journal of Alloys and Compounds, vol.249, issue.1-2, pp.33-40, 1997.
DOI : 10.1016/S0925-8388(96)02520-0

A. P. Breeman, M. De-jong, T. J. Visser, J. L. Erion, and E. P. Krenning, Optimising conditions for radiolabelling of DOTA-peptides with 90Y, 111In and 177Lu at high specific activities, European Journal of Nuclear Medicine and Molecular Imaging, vol.30, issue.6, pp.917-920, 2003.
DOI : 10.1007/s00259-003-1142-0