Epithelial cell adhesion molecule; FGF: Fibroblast growth factor ,
Human hepatocyte transplantation: current experience and future challenges, Nat Rev Gastroenterol Hepatol, vol.7, issue.5, pp.288-98, 2010. ,
Improving the Techniques for Human Hepatocyte Transplantation: Report From a Consensus Meeting in London, Cell Transplantation, vol.21, issue.1, pp.1-10, 2012. ,
DOI : 10.3727/096368911X566208
Current Status of Hepatocyte Transplantation, Transplantation, vol.93, issue.4, pp.342-349, 2012. ,
DOI : 10.1097/TP.0b013e31823b72d6
Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies, The Lancet, vol.385, issue.9967, pp.509-525, 2015. ,
DOI : 10.1016/S0140-6736(14)61376-3
Mechanisms of Liver Development: Concepts for Understanding Liver Disorders and Design of Novel Therapies, Gastroenterology, vol.137, issue.1, pp.62-79, 2009. ,
DOI : 10.1053/j.gastro.2009.03.035
Pioneer transcription factors: establishing competence for gene expression, Genes & Development, vol.25, issue.21, pp.2227-2268, 2011. ,
DOI : 10.1101/gad.176826.111
Early Cell Fate Decisions of Human Embryonic Stem Cells and Mouse Epiblast Stem Cells Are Controlled by the Same Signalling Pathways, PLoS ONE, vol.4, issue.6, 2009. ,
DOI : 10.1371/journal.pone.0006082.t002
Efficient differentiation of human embryonic stem cells to definitive endoderm, Nature Biotechnology, vol.132, issue.12, pp.1534-1575, 1163. ,
DOI : 10.1038/nbt1163
Differentiation and Enrichment of Hepatocyte-Like Cells from Human Embryonic Stem Cells In Vitro and In Vivo, Stem Cells, vol.17, issue.12, pp.3058-68, 2007. ,
DOI : 10.1634/stemcells.2007-0291
Differentiation and Transplantation of Human Embryonic Stem Cell???Derived Hepatocytes, Gastroenterology, vol.136, issue.3, pp.990-999, 2009. ,
DOI : 10.1053/j.gastro.2008.10.047
Directed differentiation of human embryonic stem cells into functional hepatic cells, Hepatology, vol.12, issue.5, pp.1229-1268, 2007. ,
DOI : 10.1002/hep.21582
Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signaling, Proceedings of the National Academy of Sciences, vol.105, issue.34, pp.12301-12307, 2008. ,
DOI : 10.1073/pnas.0806522105
Highly efficient generation of human hepatocyte-like cells from induced pluripotent stem cells, Hepatology, vol.26, issue.1, pp.297-305, 2010. ,
DOI : 10.1002/hep.23354
Human Embryonic and Rat Adult Stem Cells with Primitive Endoderm-Like Phenotype Can Be Fated to Definitive Endoderm, and Finally Hepatocyte-Like Cells, PLoS ONE, vol.72, issue.8, 2010. ,
DOI : 10.1371/journal.pone.0012101.s006
Rapid generation of mature hepatocyte-like cells from human induced pluripotent stem cells by an efficient three-step protocol, Hepatology, vol.17, issue.4, pp.1193-203, 2012. ,
DOI : 10.1002/hep.24790
Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development, Hepatology, vol.5, issue.5, pp.1754-65, 2010. ,
DOI : 10.1002/hep.23506
Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells, Journal of Clinical Investigation, vol.120, issue.9, pp.3127-3163, 2010. ,
DOI : 10.1172/JCI43122DS1
Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes, Journal of Hepatology, vol.62, issue.3, pp.581-590, 2015. ,
DOI : 10.1016/j.jhep.2014.10.016
Production of hepatocyte-like cells from human pluripotent stem cells, Nature Protocols, vol.8, issue.2, pp.430-437, 2013. ,
DOI : 10.1002/stem.199
Integration-deficient lentivectors: an effective strategy to purify and differentiate human embryonic stem cell-derived hepatic progenitors, BMC Biology, vol.11, issue.1, pp.86-96, 2013. ,
DOI : 10.1073/pnas.062038599
URL : https://hal.archives-ouvertes.fr/inserm-00852086
Identification and Characterization of Vitamin A-Storing Cells in Fetal Liver: Implications for Functional Importance of Hepatic Stellate Cells in Liver Development and Hematopoiesis, STEM CELLS, vol.24, issue.9, pp.2339-2388, 2007. ,
DOI : 10.1634/stemcells.2006-0316
Regulation of hepatic stem/progenitor phenotype by microenvironment stiffness in hydrogel models of the human liver stem cell niche, Biomaterials, vol.32, issue.30, pp.7389-402, 2011. ,
DOI : 10.1016/j.biomaterials.2011.06.042
Repopulation Efficiencies of Adult Hepatocytes, Fetal Liver Progenitor Cells, and Embryonic Stem Cell-Derived Hepatic Cells in Albumin-Promoter-Enhancer Urokinase-Type Plasminogen Activator Mice, The American Journal of Pathology, vol.175, issue.4, pp.1483-92, 2009. ,
DOI : 10.2353/ajpath.2009.090117
Differentiation and Transplantation of Human Induced Pluripotent Stem Cell-derived Hepatocyte-like Cells, Stem Cell Reviews and Reports, vol.120, issue.4, pp.493-504 ,
DOI : 10.1007/s12015-011-9330-y
In Vivo Liver Regeneration Potential of Human Induced Pluripotent Stem Cells from Diverse Origins, Science Translational Medicine, vol.3, issue.82, 2011. ,
DOI : 10.1126/scitranslmed.3002376
Direct and Indirect Contribution of Human Embryonic Stem Cell???Derived Hepatocyte-Like Cells to Liver Repair in Mice, Gastroenterology, vol.142, issue.3, pp.602-613, 2012. ,
DOI : 10.1053/j.gastro.2011.11.030
The role of HGF on invasive properties and repopulation potential of human fetal hepatic progenitor cells, Experimental Cell Research, vol.315, issue.19, pp.3396-405, 2009. ,
DOI : 10.1016/j.yexcr.2009.07.007
Repopulation of Athymic Mouse Liver by Cryopreserved Early Human Fetal Hepatoblasts, Human Gene Therapy, vol.15, issue.12, pp.1219-1247, 2004. ,
DOI : 10.1089/hum.2004.15.1219
Isolation of human progenitor liver epithelial cells with extensive replication capacity and differentiation into mature hepatocytes, J Cell Sci, vol.115, pp.2679-88, 2002. ,
Derivation, characterization, differentiation, and registration of seven human embryonic stem cell lines (VAL-3, -4, -5, -6M, -7, -8, and -9) on human feeder, In Vitro Cellular & Developmental Biology - Animal, vol.17, issue.116???118, pp.3-4317, 2010. ,
DOI : 10.1007/s11626-010-9285-3
Functional Assessment of the Quality of Human Hepatocyte Preparations for Cell Transplantation, Cell Transplantation, vol.17, issue.10, pp.10-111211, 2008. ,
DOI : 10.3727/096368908787236620
Evaluation of Cytochrome P450 Activities in Human Hepatocytes In Vitro, Methods Mol Biol, vol.806, pp.87-97, 2012. ,
DOI : 10.1007/978-1-61779-367-7_7
Validated assay for studying activity profiles of human liver UGTs after drug exposure: inhibition and induction studies, Analytical and Bioanalytical Chemistry, vol.28, issue.1, pp.2251-63, 2010. ,
DOI : 10.1007/s00216-009-3441-1
Generation of functional cholangiocyte-like cells from human pluripotent stem cells and HepaRG cells, Hepatology, vol.58, issue.2, pp.700-714, 2014. ,
DOI : 10.1002/hep.27165
URL : https://hal.archives-ouvertes.fr/hal-01169803
Optimization of the cryopreservation and thawing protocol for human hepatocytes for use in cell transplantation, Liver Transplantation, vol.16, issue.2, pp.229-266, 2010. ,
DOI : 10.1002/lt.21983
Neonatal Livers: A Source for the Isolation of Good-Performing Hepatocytes for Cell Transplantation, Cell Transplantation, vol.23, issue.10, pp.1229-1271, 2014. ,
DOI : 10.3727/096368913X669743
Animal models of fulminant hepatic failure: A critical evaluation, Liver Transplantation, vol.97, issue.1, 2000. ,
DOI : 10.1002/lt.500060110
Enhanced Functions of Human Embryonic Stem Cell-derived Hepatocyte-like Cells on Three-dimensional Nanofibrillar Surfaces, Stem Cell Reviews and Reports, vol.331, issue.2, pp.601-611, 2010. ,
DOI : 10.1007/s12015-010-9179-5
Hepatic Differentiation from Human Embryonic Stem Cells Using Stromal Cells, Journal of Surgical Research, vol.170, issue.2, pp.253-61, 2011. ,
DOI : 10.1016/j.jss.2011.06.032
Genetic factors affecting gene transcription and catalytic activity of UDP-glucuronosyltransferases in human liver, Human Molecular Genetics, vol.23, issue.20, pp.5558-69, 2014. ,
DOI : 10.1093/hmg/ddu268
The ontogeny of drug metabolism enzymes and implications for adverse drug events, Pharmacology & Therapeutics, vol.118, issue.2, pp.250-67, 2008. ,
DOI : 10.1016/j.pharmthera.2008.02.005
Human hepatic stem cells from fetal and postnatal donors, The Journal of Experimental Medicine, vol.82, issue.8, pp.1973-87, 2007. ,
DOI : 10.1016/S0963-6897(98)00008-6
Successful transplantation of human hepatic stem cells with restricted localization to liver using hyaluronan grafts???, Hepatology, vol.24, issue.9 Suppl., pp.775-84, 2013. ,
DOI : 10.1002/hep.26065
Engrafted human stem cell???derived hepatocytes establish an infectious HCV murine model, Journal of Clinical Investigation, vol.124, issue.11, pp.4953-64, 2014. ,
DOI : 10.1172/JCI75456DS1
A Mouse Model of Inducible Liver Injury Caused by Tet-On Regulated Urokinase for Studies of Hepatocyte Transplantation, The American Journal of Pathology, vol.175, issue.5, pp.1975-83, 2009. ,
DOI : 10.2353/ajpath.2009.090349
Pharmacologic cholinesterase inhibition improves survival in acetaminophen-induced acute liver failure in the mouse, BMC Gastroenterology, vol.112, issue.1, pp.148-158, 2014. ,
DOI : 10.1097/ALN.0b013e3181c5388f
Damage-associated molecular patterns: Their impact on the liver and beyond during acetaminophen overdose, Hepatology, vol.247, issue.5, pp.1599-601, 2012. ,
DOI : 10.1002/hep.25920
Thinking through acetaminophen hepatotoxicity and liver transplantation: Choosing worthy recipients, Liver Transplantation, vol.329, issue.6, pp.567-576, 2009. ,
DOI : 10.1002/lt.21728
The tumorigenicity of human embryonic and induced pluripotent stem cells, Nature Reviews Cancer, vol.471, issue.4, pp.268-77, 2011. ,
DOI : 10.1038/nrc3034
WNT signaling determines tumorigenicity and function of ESC-derived retinal progenitors, Journal of Clinical Investigation, vol.123, issue.4, pp.1647-61, 2013. ,
DOI : 10.1172/JCI65048DS1
Prolonged Maturation Culture Favors a Reduction in the Tumorigenicity and the Dopaminergic Function of Human ESC-Derived Neural Cells in a Primate Model of Parkinson's Disease, STEM CELLS, vol.107, issue.suppl 3, pp.935-980, 2012. ,
DOI : 10.1002/stem.1060
Embryoid-body cells derived from a mouse embryonic stem cell line show differentiation into functional hepatocytes, Hepatology, vol.97, issue.1, pp.22-31, 2002. ,
DOI : 10.1053/jhep.2002.34136
Donor-Derived Brain Tumor Following Neural Stem Cell Transplantation in an Ataxia Telangiectasia Patient, PLoS Medicine, vol.302, issue.2, 2009. ,
DOI : 10.1371/journal.pmed.1000029.sd001
Strange lesions after stem-cell therapy, Nature, vol.465, issue.7301, 2010. ,
DOI : 10.1038/465997a
Preclinical Studies for Induced Pluripotent Stem Cell-based Therapeutics, Journal of Biological Chemistry, vol.289, issue.8, pp.4585-93, 2014. ,
DOI : 10.1074/jbc.R113.463737
Immunogenicity and Tumorigenicity of Pluripotent Stem Cells and their Derivatives: Genetic and Epigenetic Perspectives, Current Stem Cell Research & Therapy, vol.9, issue.1, pp.63-72, 2014. ,
DOI : 10.2174/1574888X113086660068
Liver X receptor ?? (LXR??/NR1H3) regulates differentiation of hepatocyte-like cells via reciprocal regulation of HNF4??, Journal of Hepatology, vol.61, issue.6, pp.1276-86, 2014. ,
DOI : 10.1016/j.jhep.2014.07.025
Human hepatocyte transplantation: state of the art, Journal of Internal Medicine, vol.52, issue.Suppl. 1, pp.339-57, 2009. ,
DOI : 10.1111/j.1365-2796.2009.02152.x
Cellular therapies for liver replacement, Transplant Immunology, vol.12, issue.3-4, pp.3-4273, 2004. ,
DOI : 10.1016/j.trim.2003.12.008
Clinical Outcome of Hepatocyte Transplantation in Four Pediatric Patients With Inherited Metabolic Diseases, Cell Transplantation, vol.21, issue.10, pp.2267-82, 2012. ,
DOI : 10.3727/096368912X637505
Concise review: Clinical programs of stem cell therapies for liver and pancreas, STEM CELLS, vol.499, issue.10, pp.2047-60, 2013. ,
DOI : 10.1002/stem.1457
Transplantation of human fetal biliary tree stem/progenitor cells into two patients with advanced liver cirrhosis, BMC Gastroenterology, vol.18, issue.2, pp.204-214, 2014. ,
DOI : 10.1002/lt.22322
Human Embryonic Stem Cells Possess Immune-Privileged Properties, Stem Cells, vol.22, issue.4, pp.448-56, 2004. ,
DOI : 10.1634/stemcells.22-4-448
Cell and tissue engineering for liver disease, Science Translational Medicine, vol.6, issue.245, pp.245-247, 2014. ,
DOI : 10.1126/scitranslmed.3005975
Vascularized and functional human liver from an iPSC-derived organ bud transplant, Nature, vol.51, issue.7459, pp.481-485, 2013. ,
DOI : 10.1073/pnas.1109767108