K. Asada, Ascorbate peroxidase - a hydrogen peroxide-scavenging enzyme in plants, Physiologia Plantarum, vol.86, issue.2, pp.235-241, 1992.
DOI : 10.1111/j.1399-3054.1992.tb04728.x

F. Teixeira, L. Menezes-benavente, V. Galvao, R. Margis, and M. Margis-pinhiero, Rice ascorbate peroxidase gene family encodes functionally diverse isoforms localized in different subcellular compartments, Planta, vol.515, issue.2, pp.300-314, 2006.
DOI : 10.1007/s00425-005-0214-8

Z. Lu, D. Liu, and S. Liu, Two rice cytosolic ascorbate peroxidases differentially improve salt tolerance in transgenic Arabidopsis, Plant Cell Reports, vol.6, issue.3, pp.1909-1917, 2008.
DOI : 10.1007/s00299-007-0395-7

C. Wang, C. Yang, and Y. Wang, Cloning and expression analysis of an APX gene from Betula platyphylla, J NE Forest U, vol.37, pp.79-88, 2009.

C. Ma, P. Wang, and Z. Cao, cDNA cloning and gene expression of APX in Suaeda salsa in response to salt stress, J Plant Physiol, vol.28, pp.261-266, 2002.

R. Mittler and B. Zilinskas, Purification and Characterization of Pea Cytosolic Ascorbate Peroxidase, PLANT PHYSIOLOGY, vol.97, issue.3, pp.962-968, 1991.
DOI : 10.1104/pp.97.3.962

T. Yoo, C. Park, G. Lee, R. Shin, J. Yun et al., Retraction note: A hot pepper cDNA encoding ascorbate peroxidase is induced during the incompatible interaction with virus and bacteria, Molecules and Cells, vol.35, issue.2, pp.75-84, 2002.
DOI : 10.1007/s10059-013-3069-z

L. Lin, X. Wang, and Y. Wang, cDNA Clone, fusion expression and purification of the novel gene related to ascorbate peroxidase from Chinese wild Vitis pseudoreticulata in E. coli, Molecular Biology Reports, vol.41, issue.3, pp.197-206, 2006.
DOI : 10.1007/s11033-006-0008-5

J. Rane, R. Pannu, V. Sohu, R. Saini, B. Mishra et al., Performance of Yield and Stability of Advanced Wheat Genotypes under Heat Stress Environments of the Indo-Gangetic Plains, Crop Science, vol.47, issue.4, pp.1561-1573, 2007.
DOI : 10.2135/cropsci2006.07.0479

J. Padaria, D. Bhatt, K. Biswas, G. Singh, and R. Raipuria, In-silico prediction of an uncharacterized protein generated from heat responsive SSH library in wheat (Triticum aestivum L.). Plant Omics, pp.150-156, 2013.

F. Dupont, W. Hurkman, W. Vensel, C. Tanaka, K. Kothari et al., Protein accumulation and composition in wheat grains: Effects of mineral nutrients and high temperature, European Journal of Agronomy, vol.25, issue.2, pp.96-107, 2006.
DOI : 10.1016/j.eja.2006.04.003

P. Boominathan, R. Shukla, A. Kumar, D. Manna, D. Negi et al., Long Term Transcript Accumulation during the Development of Dehydration Adaptation in Cicer arietinum, PLANT PHYSIOLOGY, vol.135, issue.3, pp.1608-1620, 2004.
DOI : 10.1104/pp.104.043141

L. Liu, Y. Zhou, G. Zhou, R. Ye, L. Zhao et al., Identification of early senescence-associated genes in rice flag leaves, Plant Molecular Biology, vol.224, issue.1-2, pp.37-55, 2008.
DOI : 10.1007/s11103-008-9300-1

A. Sekman, I. Turkan, and S. Takio, Differential responses of antioxidative enzymes and lipid peroxidation to salt stress in salt-tolerant Plantago maritima and salt-sensitive Plantago media, Physiologia Plantarum, vol.53, issue.3, pp.399-411, 2007.
DOI : 10.1007/s00425-003-1105-5

J. Hernandez and M. Almansa, Short-term effects of salt stress on antioxidant systems and leaf water relations of pea leaves, Physiologia Plantarum, vol.35, issue.2, pp.251-257, 2002.
DOI : 10.1016/0168-9452(94)04048-6

A. Bas, G. Fosberg, S. Hammarstrom, and M. Hammarstrom, Utility of the Housekeeping Genes 18S rRNA, beta-Actin and Glyceraldehyde-3-Phosphate-Dehydrogenase for Normalization in Real-Time Quantitative Reverse Transcriptase-Polymerase Chain Reaction Analysis of Gene Expression in Human T Lymphocytes, Scandinavian Journal of Immunology, vol.45, issue.6, pp.566-573, 2004.
DOI : 10.1016/S0022-1759(01)00489-6

J. Bunkelmann and R. Trelease, Ascorbate Peroxidase (A Prominent Membrane Protein in Oilseed Glyoxysomes), Plant Physiology, vol.110, issue.2, pp.589-598, 1996.
DOI : 10.1104/pp.110.2.589

A. Kubo, H. Saji, K. Tanaka, and N. Kondo, Cloning and sequencing of a cDNA encoding ascorbate peroxidase fromArabidopsis thaliana, Plant Molecular Biology, vol.96, issue.4, pp.691-701, 1992.
DOI : 10.1007/BF00020011

W. Shi, Y. Muramoto, A. Ueda, and T. Takebe, Cloning of peroxisomal ascorbate peroxidase gene from barley and enhanced thermotolerance by overexpressing in Arabidopsis thaliana, Gene, vol.273, issue.1, pp.23-27, 2001.
DOI : 10.1016/S0378-1119(01)00566-2

H. Zhang, J. Wang, U. Nickel, R. Allen, and H. Goodman, Cloning and expression of an Arabidopsis gene encoding a putative peroxisomal ascorbate peroxidase, Plant Molecular Biology, vol.34, issue.6, pp.967-971, 1997.
DOI : 10.1023/A:1005814109732

A. Katiyar, S. Lenka, K. Lakshmi, V. Chinnusamy, and K. Bansal, In Silico Characterization and Homology Modeling of Thylakoid bound Ascorbate Peroxidase from a Drought Tolerant Wheat Cultivar, Genomics, Proteomics & Bioinformatics, vol.7, issue.4, 2009.
DOI : 10.1016/S1672-0229(08)60048-0

C. Kaya, S. Aydemir, O. Sonmez, M. Ashraf, and M. Dikilitas, Regulation of growth and some key physiological processes in salt-stressed maize (Zea mays L.) plants by exogenous application of asparagine and glycerol, Acta Botanica Croatica, vol.72, issue.1, pp.157-168, 2013.
DOI : 10.2478/v10184-012-0012-x

R. Morimoto, Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators, Genes & Development, vol.12, issue.24, pp.3788-3796, 1998.
DOI : 10.1101/gad.12.24.3788

R. Kumar, S. Sharma, K. Gadpayle, K. Singh, R. Sivaranjani et al., Mechanism of action of hydrogen peroxide in wheat thermotolerant-interaction between antioxidants isoenzymes, proline and cell membrane, Afr J Biotechnol, vol.2012, issue.78, pp.1114368-14379

R. Heath and L. Packer, Photoperoxidation in isolated chloroplasts, Archives of Biochemistry and Biophysics, vol.125, issue.1, p.189, 1968.
DOI : 10.1016/0003-9861(68)90654-1

D. Bhatt, S. Saxena, S. Jain, A. Dobriyal, M. Majee et al., Cloning, expression and functional validation of drought inducible ascorbate peroxidase (Ec-apx1) from Eleusine coracana, Molecular Biology Reports, vol.123, issue.13, pp.1155-1165
DOI : 10.1007/s11033-012-2157-z

J. Sambrook and D. Russell, Molecular Cloning. In A Laboratory Manual, 2001.

A. Shevchenko, H. Tomas, J. Havlis, J. Olsen, and M. Mann, In-gel digestion for mass spectrometric characterization of proteins and proteomes, Nature Protocols, vol.5, issue.6, pp.2856-2860, 2006.
DOI : 10.1038/nprot.2006.468

S. Altschul, W. Gish, W. Miller, E. Myers, and D. Lipman, Basic local alignment search tool, Journal of Molecular Biology, vol.215, issue.3, pp.403-410, 1990.
DOI : 10.1016/S0022-2836(05)80360-2

F. Slevers, A. Wilm, D. Dineen, T. Gibson, K. Karpus et al., Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega, Molecular Systems Biology, vol.7, issue.1, p.539, 2011.
DOI : 10.1093/nar/gkn174

K. Tamura, J. Dudley, M. Nei, and S. Kumar, MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0, Molecular Biology and Evolution, vol.24, issue.8, pp.1596-1599, 2007.
DOI : 10.1093/molbev/msm092

C. Sigrist, E. De-castro, L. Cerutti, B. Cuche, N. Hulo et al., New and continuing developments at PROSITE, Nucleic Acids Research, vol.41, issue.D1, pp.344-347, 2012.
DOI : 10.1093/nar/gks1067

M. Punta, P. Coggill, R. Eberhardt, J. Mistry, J. Tate et al., The Pfam protein families database, Nucleic Acids Research, vol.40, issue.D1, pp.290-301, 2012.
DOI : 10.1093/nar/gkr1065

URL : https://hal.archives-ouvertes.fr/hal-01294685

A. Marchler-bauer, C. Zheng, F. Chitsaz, M. Derbyshire, L. Geer et al., CDD: conserved domains and protein three-dimensional structure, Nucleic Acids Research, vol.41, issue.D1, pp.348-352, 2013.
DOI : 10.1093/nar/gks1243

E. Gasteiger, C. Hoogland, A. Gattiker, S. Duvaud, M. Wilkins et al., Protein Identification and Analysis Tools on the ExPASy Server, The Proteomics Protocols Handbook. Edited by Walker JM. New Jersey: Humana, pp.571-607, 2005.
DOI : 10.1385/1-59259-890-0:571

J. Garnier, J. Gibrat, and B. Robson, [32] GOR method for predicting protein secondary structure from amino acid sequence, Methods Enzymol, vol.266, pp.540-553, 1996.
DOI : 10.1016/S0076-6879(96)66034-0

S. Altschul, T. Madden, A. Schäffer, J. Zhang, Z. Zhang et al., Gapped BLAST and PSI-BLAST: a new generation of protein database search programs, Nucleic Acids Research, vol.25, issue.17, pp.3389-3402, 1997.
DOI : 10.1093/nar/25.17.3389

L. Kelley and M. Sternberg, Protein structure prediction on the Web: a case study using the Phyre server, Nature Protocols, vol.5, issue.3, pp.363-371, 2009.
DOI : 10.1093/nar/gkm977

C. Lambert, N. Leonard, X. De-bolle, and E. Depiereux, ESyPred3D: Prediction of proteins 3D structures, Bioinformatics, vol.18, issue.9, pp.1250-1256, 2002.
DOI : 10.1093/bioinformatics/18.9.1250

C. Chen, J. Hwang, and J. Yang, (PS)2: protein structure prediction server, Nucleic Acids Research, vol.34, issue.Web Server, pp.152-157, 2006.
DOI : 10.1093/nar/gkl187

K. Arnold, L. Bordoli, J. Kopp, and T. Schwede, The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling, Bioinformatics, vol.22, issue.2, pp.195-201, 2006.
DOI : 10.1093/bioinformatics/bti770

P. Bates, L. Kelley, R. Maccallum, and M. Sternberg, Enhancement of protein modeling by human intervention in applying the automatic programs 3D-JIGSAW and 3D-PSSM, Proteins: Structure, Function, and Genetics, vol.88, issue.S5, pp.39-46, 2001.
DOI : 10.1002/prot.1168

. Zhang, I-TASSER server for protein 3D structure prediction, BMC Bioinformatics, vol.9, issue.1, p.40, 2008.
DOI : 10.1186/1471-2105-9-40

R. Laskoswki, M. Macarthur, D. Moss, and J. Thorton, PROCHECK: a program to check the stereochemical quality of protein structures, Journal of Applied Crystallography, vol.26, issue.2, pp.283-291, 1993.
DOI : 10.1107/S0021889892009944

R. Luthy, J. Bowie, and D. Eisenberg, Assessment of protein models with three-dimensional profiles, Nature, vol.356, issue.6364, pp.83-85, 1992.
DOI : 10.1038/356083a0

P. Benkert, M. Kunzli, and T. Schwede, QMEAN server for protein model quality estimation, Nucleic Acids Research, vol.37, issue.Web Server, pp.510-514, 2009.
DOI : 10.1093/nar/gkp322

W. Delano, The PyMOL Molecular Graphics System, 2002.

J. Gelly, A. Joseph, N. Srinivasan, and A. De-brevern, iPBA: a tool for protein structure comparison using sequence alignment strategies, Nucleic Acids Research, vol.39, issue.suppl, pp.18-23, 2011.
DOI : 10.1093/nar/gkr333

URL : https://hal.archives-ouvertes.fr/inserm-00646241

A. Laurie and R. Jackson, Q-SiteFinder: an energy-based method for the prediction of protein-ligand binding sites, Bioinformatics, vol.21, issue.9, 1909.
DOI : 10.1093/bioinformatics/bti315

O. Trott and A. Olson, AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading, Journal of Computational Chemistry, vol.17, pp.455-461, 2010.
DOI : 10.1002/jcc.21334

E. Bolton, Y. Wang, P. Thiessen, and S. Bryant, PubChem: Integrated Platform of Small Molecules and Biological Activities, Annual Reports in Computational Chemistry, 2008.
DOI : 10.1016/S1574-1400(08)00012-1

O. Boyle, N. Banck, M. James, C. Morley, C. Vandermeersch et al., Open Babel: An open chemical toolbox, Journal of Cheminformatics, vol.3, issue.1, p.33, 2011.
DOI : 10.1093/nar/gkp324

G. Morris, R. Huey, W. Lindstrom, M. Sanner, R. Belew et al., AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility, Journal of Computational Chemistry, vol.22, issue.16, pp.2785-2791, 2009.
DOI : 10.1002/jcc.21256