Adrenocortical cancer: pathophysiology and clinical management, Endocrine Related Cancer, vol.14, issue.1, pp.13-28, 2007. ,
DOI : 10.1677/erc.1.01130
Combination Chemotherapy in Advanced Adrenocortical Carcinoma, New England Journal of Medicine, vol.366, issue.23, pp.2189-2197, 2012. ,
DOI : 10.1056/NEJMoa1200966
THE WNT SIGNALING PATHWAY IN DEVELOPMENT AND DISEASE, Annual Review of Cell and Developmental Biology, vol.20, issue.1, pp.781-810, 2004. ,
DOI : 10.1146/annurev.cellbio.20.010403.113126
Wnt signaling in stem and cancer stem cells, Current Opinion in Cell Biology, vol.25, issue.2, pp.254-264, 2013. ,
DOI : 10.1016/j.ceb.2013.01.004
On the role of Wnt/??-catenin signaling in stem cells, Biochimica et Biophysica Acta (BBA) - General Subjects, vol.1830, issue.2, pp.2297-2306, 2013. ,
DOI : 10.1016/j.bbagen.2012.08.010
Wnt/??-Catenin Signaling and Disease, Cell, vol.149, issue.6, pp.1192-1205, 2012. ,
DOI : 10.1016/j.cell.2012.05.012
Targeted disruption of beta-catenin in Sf1-expressing cells impairs development and maintenance of the adrenal cortex, Development, vol.135, pp.2593-2602, 2008. ,
Integrated genomic characterization of adrenocortical carcinoma, Nature Genetics, vol.11, issue.6, pp.607-612, 2014. ,
DOI : 10.1038/ng.2953
URL : https://hal.archives-ouvertes.fr/hal-01255809
Constitutive ??-catenin activation induces adrenal hyperplasia and promotes adrenal cancer development, Human Molecular Genetics, vol.19, issue.8, pp.1561-1576, 2010. ,
DOI : 10.1093/hmg/ddq029
Progression to Adrenocortical Tumorigenesis in Mice and Humans through Insulin-Like Growth Factor 2 and ??-Catenin, The American Journal of Pathology, vol.181, issue.3, pp.1017-1033, 2012. ,
DOI : 10.1016/j.ajpath.2012.05.026
The T cell factor/??-Catenin Antagonist PKF115???584 Inhibits Proliferation of Adrenocortical Carcinoma Cells, The Journal of Clinical Endocrinology & Metabolism, vol.93, issue.8, pp.3222-3225, 2008. ,
DOI : 10.1210/jc.2008-0247
URL : https://hal.archives-ouvertes.fr/hal-00315009
Silencing Mutated ??-Catenin Inhibits Cell Proliferation and Stimulates Apoptosis in the Adrenocortical Cancer Cell Line H295R, PLoS ONE, vol.93, issue.2, p.55743, 2013. ,
DOI : 10.1371/journal.pone.0055743.s001
Transcriptome Analysis Reveals that p53 and ??-Catenin Alterations Occur in a Group of Aggressive Adrenocortical Cancers, Cancer Research, vol.70, issue.21, pp.8276-8281, 2010. ,
DOI : 10.1158/0008-5472.CAN-10-2014
FRA2A Is a CGG Repeat Expansion Associated with Silencing of AFF3, PLoS Genetics, vol.21, issue.1, p.1004242, 2014. ,
DOI : 10.1371/journal.pgen.1004242.s004
Functional characterization of the AFF (AF4/FMR2) family of RNA-binding proteins: insights into the molecular pathology of FRAXE intellectual disability, Human Molecular Genetics, vol.20, issue.10, pp.1873-1885, 2011. ,
DOI : 10.1093/hmg/ddr069
URL : https://hal.archives-ouvertes.fr/hal-00660261
The Super Elongation Complex Family of RNA Polymerase II Elongation Factors: Gene Target Specificity and Transcriptional Output, Molecular and Cellular Biology, vol.32, issue.13, pp.2608-2617, 2012. ,
DOI : 10.1128/MCB.00182-12
Pharmacological modulation of beta-catenin and its applications in cancer therapy, Journal of Cellular and Molecular Medicine, vol.4, issue.4, pp.449-456, 2013. ,
DOI : 10.1111/jcmm.12033
Mutations of beta-catenin in adrenocortical tumors: activation of the Wnt signaling pathway is a frequent event in both benign and malignant adrenocortical tumors, Cancer Res, vol.65, pp.7622-7627, 2005. ,
Wnt/??-Catenin and 3???,5???-Cyclic Adenosine 5???-Monophosphate/Protein Kinase A Signaling Pathways Alterations and Somatic ??-Catenin Gene Mutations in the Progression of Adrenocortical Tumors, The Journal of Clinical Endocrinology & Metabolism, vol.93, issue.10, pp.4135-4140, 2008. ,
DOI : 10.1210/jc.2008-0631
Frequent mutations of beta-catenin gene in sporadic secreting adrenocortical adenomas, Clin Endocrinol (Oxf), vol.68, pp.264-270, 2008. ,
Wnt/??catenin signaling in adrenocortical stem/progenitor cells: Implications for adrenocortical carcinoma, Annales d'Endocrinologie, vol.70, issue.3, p.156, 2009. ,
DOI : 10.1016/j.ando.2009.02.006
??-Catenin Activation Is Associated with Specific Clinical and Pathologic Characteristics and a Poor Outcome in Adrenocortical Carcinoma, Clinical Cancer Research, vol.17, issue.2, pp.328-336, 2011. ,
DOI : 10.1158/1078-0432.CCR-10-2006
Wnt/??-Catenin Pathway Activation in Adrenocortical Adenomas Is Frequently due to Somatic CTNNB1-Activating Mutations, Which Are Associated with Larger and Nonsecreting Tumors: A Study in Cortisol-Secreting and -Nonsecreting Tumors, The Journal of Clinical Endocrinology & Metabolism, vol.96, issue.2, pp.419-426, 2011. ,
DOI : 10.1210/jc.2010-1885
LAF4, anAF4-related gene, is fused toMLL in infant acute lymphoblastic leukemia, Genes, Chromosomes and Cancer, vol.88, issue.1, pp.92-96, 2002. ,
DOI : 10.1002/gcc.10091
Fusion of an AF4-related gene, LAF4, to MLL in childhood acute lymphoblastic leukemia with t(2;11)(q11;q23), Oncogene, vol.22, issue.18, pp.2851-2855, 2003. ,
DOI : 10.1038/sj.onc.1206389
The super elongation complex (SEC) and MLL in development and disease, Genes & Development, vol.25, issue.7, pp.661-672, 2011. ,
DOI : 10.1101/gad.2015411
The Mouse Laf4 Gene: Exon/Intron Organization, cDNA Sequence, Alternative Splicing, and Expression during Central Nervous System Development, Genomics, vol.80, issue.1, pp.31-37, 2002. ,
DOI : 10.1006/geno.2002.6796
Triangular tibia with fibular aplasia associated with a microdeletion on 2q11.2 encompassing LAF4, Clinical Genetics, vol.80, issue.1, pp.560-565, 2008. ,
DOI : 10.1111/j.1399-0004.2008.01050.x
Laf4/Aff3, a Gene Involved in Intellectual Disability, Is Required for Cellular Migration in the Mouse Cerebral Cortex, PLoS ONE, vol.65, issue.8, p.105933, 2014. ,
DOI : 10.1371/journal.pone.0105933.s003
Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes, Human Molecular Genetics, vol.18, issue.13, pp.2518-2522, 2009. ,
DOI : 10.1093/hmg/ddp177
Investigation of potential non-HLA rheumatoid arthritis susceptibility loci in a European cohort increases the evidence for nine markers, Annals of the Rheumatic Diseases, vol.69, issue.8, pp.1548-1553, 2010. ,
DOI : 10.1136/ard.2009.121020
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci, Nature Genetics, vol.447, issue.6, pp.508-514, 2010. ,
DOI : 10.1038/ng.468
Genome-wide association study of rheumatoid arthritis in Koreans: Population-specific loci as well as overlap with European susceptibility loci, Arthritis & Rheumatism, vol.6, issue.4, pp.884-893, 2011. ,
DOI : 10.1002/art.30235
Statistical colocalization of monocyte gene expression and genetic risk variants for type 1 diabetes, Human Molecular Genetics, vol.21, issue.12, pp.2815-2824, 2012. ,
DOI : 10.1093/hmg/dds098
New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes, PLoS Genetics, vol.8, issue.9, p.1002921, 2012. ,
DOI : 10.1371/journal.pgen.1002921.s019
The Genetic Basis of Graves Disease, Current Genomics, vol.12, issue.8, pp.542-563, 2011. ,
DOI : 10.2174/138920211798120772
LAF-4 is aberrantly expressed in human breast cancer, Int J Cancer, vol.115, pp.568-574, 2005. ,
beta -Catenin, a novel prognostic marker for breast cancer: Its roles in cyclin D1 expression and cancer progression, Proceedings of the National Academy of Sciences, vol.97, issue.8, pp.4262-4266, 2000. ,
DOI : 10.1073/pnas.060025397
Nuclear Speckles, Cold Spring Harbor Perspectives in Biology, vol.3, issue.2, 2011. ,
DOI : 10.1101/cshperspect.a000646
An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription, Proceedings of the National Academy of Sciences, vol.111, issue.4, pp.1491-1496, 2014. ,
DOI : 10.1073/pnas.1323535111
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia, Nature, vol.461, issue.7370, pp.529-533, 2011. ,
DOI : 10.1038/nature10509
BET Bromodomain Inhibition as??a Therapeutic Strategy to Target c-Myc, Cell, vol.146, issue.6, pp.904-917, 2011. ,
DOI : 10.1016/j.cell.2011.08.017
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia, Nature, vol.41, issue.7370, pp.524-528, 2011. ,
DOI : 10.1038/nature10334
Loss of expression of the ubiquitous transcription factor cAMP response element-binding protein (CREB) and compensatory overexpression of the activator CREMtau in the human adrenocortical cancer cell line H295R, J Clin Endocrinol Metab, vol.85, pp.345-354, 2000. ,
Inactivation of the Carney Complex Gene 1 (Protein Kinase A Regulatory Subunit 1A) Inhibits SMAD3 Expression and TGF??-Stimulated Apoptosis in Adrenocortical Cells, Cancer Research, vol.69, issue.18, pp.7278-7284, 2009. ,
DOI : 10.1158/0008-5472.CAN-09-1601
Mutations in Macronodular Adrenal Hyperplasia with Cushing's Syndrome, New England Journal of Medicine, vol.369, issue.22, pp.2105-2114, 2013. ,
DOI : 10.1056/NEJMoa1304603
Increased Steroidogenic Factor-1 Dosage Triggers Adrenocortical Cell Proliferation and Cancer, Molecular Endocrinology, vol.21, issue.12, pp.2968-2987, 2007. ,
DOI : 10.1210/me.2007-0120
URL : https://hal.archives-ouvertes.fr/hal-00172059
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles, Proceedings of the National Academy of Sciences, vol.102, issue.43, pp.15545-15550, 2005. ,
DOI : 10.1073/pnas.0506580102
A guided tour into subcellular colocalization analysis in light microscopy, Journal of Microscopy, vol.56, issue.3, pp.213-232, 2006. ,
DOI : 10.1016/S0014-5793(03)00521-0
URL : https://hal.archives-ouvertes.fr/hal-00132481