M. T. Abreu, P. Vora, E. Faure, L. S. Thomas, E. T. Arnold et al., Decreased Expression of Toll-Like Receptor-4 and MD-2 Correlates with Intestinal Epithelial Cell Protection Against Dysregulated Proinflammatory Gene Expression in Response to Bacterial Lipopolysaccharide, The Journal of Immunology, vol.167, issue.3, pp.1609-1616, 2001.
DOI : 10.4049/jimmunol.167.3.1609

H. Akinbi, J. Meinzen-derr, C. Auer, Y. Ma, D. Pullum et al., Alterations in the Host Defense Properties of Human Milk Following Prolonged Storage or Pasteurization, Journal of Pediatric Gastroenterology and Nutrition
DOI : 10.1097/MPG.0b013e3181e07f0a

J. M. Alessandri, J. L. Joannic, S. Delpals, and G. Durand, Effect of Early Dietary Deficiency in Polyunsaturated Fatty Acids on Two Lectin Binding Sites in the Small Intestine of Postweanling Rats, Journal of Pediatric Gastroenterology and Nutrition, vol.21, issue.2, pp.165-176, 1995.
DOI : 10.1097/00005176-199508000-00008

A. M. Al-majali, E. K. Asem, C. Lamar, J. P. Robinson, J. Freeman et al., Insulin Modulates Intestinal Response of Suckling Mice to the Escherichia Coli Heat-Stable Enterotoxin
DOI : 10.1007/978-1-4615-4143-1_9

Y. Andersson, K. Sävman, L. Bläckberg, and O. Hernell, Pasteurization of mother's own milk reduces fat absorption and growth in preterm infants, Acta Paediatrica, vol.27, issue.10, pp.961445-1449, 2007.
DOI : 10.1203/00006450-200002000-00006

E. L. Andersson, O. Hernell, L. Bläckberg, H. Fält, and S. Lindquist, BSSL and PLRP2: key enzymes for lipid digestion in the newborn examined using the Caco-2 cell line, The Journal of Lipid Research, vol.52, issue.11, pp.521949-1956, 2011.
DOI : 10.1194/jlr.M015685

A. Anc and A. , Actualisation des Apports Nutritionnels Conseillés pour les acides gras. Rapport d'expertise collective, 2011.

M. Armand, M. Hamosh, N. R. Mehta, P. A. Angelus, J. R. Philpott et al., Effect of Human Milk or Formula on Gastric Function and Fat Digestion in the Premature Infant1, Pediatric Research, vol.105, issue.3, pp.429-437, 1996.
DOI : 10.1203/00006450-199609000-00011

M. Armand, Le lait maternel: source de probiotiques! Actualités en Diététique et Nutrition, pp.113-129, 2009.

M. Armand and G. S. Pieroni, Inventors; Innovation Santé des Lipides (I Foodstuff composition to improve digestibility of Foodstuff lipids

M. Armand, Chapitre 25 Stratégies de contrôle de la biodisponibilité des lipides In : Structure des aliments et effets nutritionnels, pp.373-413, 2013.

S. Arslanoglu, W. Corpeleijn, G. Moro, C. Braegger, C. Campoy et al., Donor Human Milk for Preterm Infants, Journal of Pediatric Gastroenterology and Nutrition, vol.57, issue.4, pp.535-542
DOI : 10.1097/MPG.0b013e3182a3af0a

L. M. Arterburn, E. B. Hall, and H. Oken, Distribution, interconversion , and dose response of n-3 fatty acids in humans, Am. J. Clin. Nutr, issue.6, pp.831467-1476, 2006.

M. Awada, C. O. Soulage, A. Meynier, C. Debard, P. Plaisancié et al., Dietary oxidized n-3 PUFA induce oxidative stress and inflammation: role of intestinal absorption of 4-HHE and reactivity in intestinal cells, The Journal of Lipid Research, vol.53, issue.10, pp.532069-2080
DOI : 10.1194/jlr.M026179

URL : https://hal.archives-ouvertes.fr/inserm-00725905

S. Aydin, S. Aydin, Y. Ozkan, and S. Kumru, Ghrelin is present in human colostrum, transitional and mature milk, Peptides, vol.27, issue.4, pp.878-882, 2006.
DOI : 10.1016/j.peptides.2005.08.006

S. Aydin, Y. Ozkan, F. Erman, B. Gurates, N. Kilic et al., Presence of obestatin in breast milk: Relationship among obestatin, ghrelin, and leptin in lactating women, Nutrition, vol.24, issue.7-8, pp.7-8689, 2008.
DOI : 10.1016/j.nut.2008.03.020

S. E. Balmer, P. H. Scott, and B. A. Wharton, Diet and faecal flora in the newborn: lactoferrin., Archives of Disease in Childhood, vol.64, issue.12, pp.1685-1690, 1987.
DOI : 10.1136/adc.64.12.1685

C. L. Berseth, J. A. Bisquera, V. U. Paje, C. Sebban-kreuzer, S. Rouvellac et al., Prolonging small feeding volumes early in life decreases the incidence of necrotizing enterocolitis in very low birth weight infants Individual and combined action of pancreatic lipase and pancreatic lipase-related proteins 1 and 2 on native versus homogenized milk fat globules, Pediatrics Mol. Nutr. Food Res, vol.111, issue.2112, pp.529-534, 2003.

J. Bielicki, R. Huch, U. A. Von-mandach, R. Bromiker, M. Wilschanski et al., Time-course of leptin levels in term and preterm human milk, European Journal of Endocrinology, vol.151, issue.2, pp.271-276192, 2004.
DOI : 10.1530/eje.0.1510271

M. Biton, A. Levin, M. Slyper, I. Alkalay, E. Horwitz et al., Epithelial microRNAs regulate gut mucosal immunity via epithelium???T cell crosstalk, Nature Immunology, vol.179, issue.3, pp.239-246, 2011.
DOI : 10.1126/science.1140956

D. R. Blais, J. Harrold, and I. Altosaar, Killing the Messenger in the Nick of Time: Persistence of Breast Milk sCD14 in the Neonatal Gastrointestinal Tract, Pediatric Research, vol.71, issue.3, pp.371-376, 2002.
DOI : 10.1203/01.pdr.0000199907.61549.94

H. Blencowe, S. Cousens, M. Z. Oestergaard, D. Chou, A. B. Moller et al., National, Regional, and Worldwide Estimates of Preterm Birth Rates in the Year 2010 With Time Trends Since 1990 for Selected Countries, Obstetric Anesthesia Digest, vol.33, issue.3, pp.2162-2172, 2010.
DOI : 10.1097/01.aoa.0000432360.25014.c3

S. Bokor, B. Koletzko, and T. Decsi, Systematic Review of Fatty Acid Composition of Human Milk from Mothers of Preterm Compared to Full-Term Infants, Annals of Nutrition and Metabolism, vol.51, issue.6, pp.51550-556, 2007.
DOI : 10.1159/000114209

R. C. Bone, R. A. Balk, F. B. Cerra, R. P. Dellinger, A. M. Fein et al., Definitions for Sepsis and Organ Failure and Guidelines for the Use of Innovative Therapies in Sepsis, Chest, vol.101, issue.6, pp.1644-1655, 1992.
DOI : 10.1378/chest.101.6.1644

A. Borthakur, S. Bhattacharyya, A. Kumar, A. N. Anbazhagan, J. K. Tobacman et al., Lactobacillus acidophilus Alleviates Platelet-Activating Factor-Induced Inflammatory Responses in Human Intestinal Epithelial Cells, PLoS ONE, vol.28, issue.10, p.75664, 2013.
DOI : 10.1371/journal.pone.0075664.g006

C. A. Boyd, M. A. Quigley, and P. Brocklrhurst, Donor breast milk versus infant formula for preterm infants: systematic review and meta-analysis, Archives of Disease in Childhood - Fetal and Neonatal Edition, vol.92, issue.3, pp.169-175, 2007.
DOI : 10.1136/adc.2005.089490

P. Brandtzaeg, Gate-keeper function of the intestinal epithelium, Beneficial Microbes, vol.4, issue.1
DOI : 10.3920/BM2012.0024

J. T. Brenna, B. Varamini, R. G. Jensen, D. A. Diersen-schade, J. A. Boettcher et al., Docosahexaenoic and arachidonic acid concentrations in human breast milk worldwide, Am. J. Clin. Nutr, issue.6, pp.851457-1464, 2007.

J. Bronsky, M. Karpisek, E. Bronská, M. Pechová, B. Jancíková et al., Adiponectin, Adipocyte Fatty Acid Binding Protein, and Epidermal Fatty Acid Binding Protein: Proteins Newly Identified in Human Breast Milk, Clinical Chemistry, vol.52, issue.9, pp.521763-1770, 2006.
DOI : 10.1373/clinchem.2005.063032

V. Buccigrossi, G. De-marco, E. Bruzzese, L. Ombrato, I. Bracale et al., Lactoferrin Induces Concentration-Dependent Functional Modulation of Intestinal Proliferation and Differentiation, Pediatric Research, vol.186, issue.4, pp.61410-414, 2007.
DOI : 10.1203/pdr.0b013e3180332c8d

D. G. Burrin and B. Stoll, Key nutrients and growth factors for the neonatal gastrointestinal tract, Clinics in Perinatology, vol.29, issue.1, pp.65-96, 2002.
DOI : 10.1016/S0095-5108(03)00065-4

R. Cabrera-rubio, M. C. Collado, K. Laitinen, S. Salminen, E. Isolauri et al., The human milk microbiome changes over lactation and is shaped by maternal weight and mode of delivery, American Journal of Clinical Nutrition, vol.96, issue.3
DOI : 10.3945/ajcn.112.037382

L. Campanella, E. Martini, and M. Tomassetti, New immunosensor for Lactoferrin determination in human milk and several pharmaceutical dairy milk products recommended for the unweaned diet, Journal of Pharmaceutical and Biomedical Analysis, vol.48, issue.2
DOI : 10.1016/j.jpba.2007.12.010

M. S. Caplan, T. Russell, Y. Xiao, M. Amer, S. Kaup et al., Effect of Polyunsaturated Fatty Acid (PUFA) Supplementation on Intestinal Inflammation and Necrotizing Enterocolitis (NEC) in a Neonatal Rat Model, Pediatric Research, vol.122, issue.5, pp.647-652, 2001.
DOI : 10.1203/00006450-200105000-00007

S. E. Carlson, M. B. Montalto, D. L. Ponder, S. H. Werkman, and S. B. Korones, Lower Incidence of Necrotizing Enterocolitis in Infants Fed a Preterm Formula with Egg Phospholipids, Pediatric Research, vol.34, issue.4, pp.491-498, 1998.
DOI : 10.1203/00006450-199810000-00005

V. P. Carnielli, M. Simonato, G. Verlato, I. Luijendijk, D. Curtis et al., Synthesis of long-chain polyunsaturated fatty acids in preterm newborns fed formula with long-chain polyunsaturated fatty acids, Am. J. Clin. Nutr, issue.5, pp.861323-1330, 2007.

X. Casabiell, V. Piñeiro, M. A. Tomé, R. Peinó, C. Diéguez et al., Presence of Leptin in Colostrum and/or Breast Milk from Lactating Mothers: A Potential Role in the Regulation of Neonatal Food Intake, The Journal of Clinical Endocrinology & Metabolism, vol.82, issue.12, pp.824270-4273, 1997.
DOI : 10.1210/jcem.82.12.4590

C. Castellote, R. Casillas, C. Ramírez-santana, F. J. Pérez-cano, M. Castell et al., Premature Delivery Influences the Immunological Composition of Colostrum and Transitional and Mature Human Milk, Journal of Nutrition, vol.141, issue.6, pp.1411181-1187, 2011.
DOI : 10.3945/jn.110.133652

C. Catassi, A. Bonuccia, G. V. Coppa, A. Carluccia, and P. L. Giorgi, Intestinal Permeability. Changes during the First Month, Journal of Pediatric Gastroenterology and Nutrition, vol.21, issue.4, pp.383-386, 1995.
DOI : 10.1097/00005176-199511000-00003

C. J. Chantry, K. Israel-ballard, Z. Moldoveanu, J. Peerson, A. Coutsoudis et al., Effect of Flash-Heat Treatment on Immunoglobulins in Breast Milk, JAIDS Journal of Acquired Immune Deficiency Syndromes, vol.51, issue.3, pp.264-267373, 2004.
DOI : 10.1097/QAI.0b013e3181aa12f2

X. Chen, C. Gao, H. Li, L. Huang, Q. Sun et al., Identification and characterization of microRNAs in raw milk during different periods of lactation, commercial fluid, and powdered milk products, Cell Research, vol.12, issue.10, pp.201128-1137, 2010.
DOI : 10.1186/1758-907X-1-7

M. Chichlowski, G. De-lartigue, J. B. German, H. E. Raybould, and D. A. Mills, Bifidobacteria isolated from infants and cultured on human milk oligosaccharides affect intestinal epithelial function Ultraviolet-C irradiation: a novel pasteurization method for donor human milk, J. Pediatr . Gastroenterol. Nutr. PLoS One, vol.2012, issue.86, pp.321-327, 2013.

M. C. Collado, K. Laitinen, S. Salminen, and E. Isolauri, Maternal weight and excessive weight gain during pregnancy modify the immunomodulatory potential of breast milk, Pediatric Research, vol.88, issue.1, pp.77-85
DOI : 10.1016/j.cmpb.2003.08.004

C. E. Commare and K. A. Tappenden, Development of the Infant Intestine: Implications for Nutrition Support, Nutrition in Clinical Practice, vol.22, issue.2, pp.159-173, 2007.
DOI : 10.1016/S0002-9610(02)00805-X

G. V. Coppa, L. Zampini, T. Galeazzi, O. Gabrielli, W. E. Corpeleijn et al., Prebiotics in human milk: a review Effect of enteral IGF-1 supplementation on feeding tolerance, growth, and gut permeability in enterally fed premature neonates, Dig. Liver Dis J. Pediatr. Gastroenterol. Nutr, vol.38, issue.462, pp.291-294184, 2006.

C. Czank, K. Simmer, and P. Hartmann, Simultaneous pasteurization and homogenization of human milk by combining heat and ultrasound: effect on milk quality, Journal of Dairy Research, vol.31, issue.02, pp.183-189, 2010.
DOI : 10.1038/sj.jp.7200533

J. Dalli, R. A. Colas, and C. N. Serhan, Novel n-3 Immunoresolvents: Structures and Actions, Scientific Reports, vol.7, 1940.
DOI : 10.1038/srep01940

C. Dani, R. Biadaioli, G. Bertini, E. Martelli, and F. F. Rubaltelli, Probiotics Feeding in Prevention of Urinary Tract Infection, Bacterial Sepsis and Necrotizing Enterocolitis in Preterm Infants, Neonatology, vol.82, issue.2, pp.103-108, 2002.
DOI : 10.1159/000063096

U. N. Das, Essential fatty acids as possible enhancers of the beneficial actions of probiotics, Nutrition, vol.18, issue.9, pp.786-789, 2002.
DOI : 10.1016/S0899-9007(02)00840-7

L. A. Davidson and B. Lonnerdal, Persistence of Human Milk Proteins in the Breast-Fed Infant, Acta Paediatrica, vol.49, issue.5, pp.733-740, 1987.
DOI : 10.1016/S0022-3476(81)80332-0

A. S. Debertin, S. Körwitz, T. Tschernig, W. J. Kleemann, and W. Götz, Tissue distribution of components of the insulin-like growth factor system in sudden infant death and controls, Forensic Science International, vol.113, issue.1-3, pp.1-3199, 2000.
DOI : 10.1016/S0379-0738(00)00205-X

D. Leoz, M. L. Wu, S. Strum, J. S. Niñonuevo, M. R. Gaerlan et al., A quantitative and comprehensive method to analyze human milk oligosaccharide structures in the urine and feces of infants, Anal. Bioanal. Chem, vol.2013, issue.12, pp.4054089-4105

E. J. Dial, M. Zayat, M. Lopez-storey, D. Tran, and L. Lichtenberger, ORAL PHOSPHATIDYLCHOLINE PRESERVES THE GASTROINTESTINAL MUCOSAL BARRIER DURING LPS-INDUCED INFLAMMATION, Shock, vol.30, issue.6, pp.30729-733, 2008.
DOI : 10.1097/SHK.0b013e318173e8d4

H. Doneray, Z. Orbak, and L. Yildiz, The relationship between breast milk leptin and neonatal weight gain, Acta Paediatrica, vol.27, issue.4, pp.643-647, 2009.
DOI : 10.1111/j.1651-2227.2008.01192.x

R. D. Duan, L. Nyberg, and A. Nilsson, Alkaline sphingomyelinase activity in rat gastrointestinal tract: distribution and characteristics, Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, vol.1259, issue.1, pp.125949-55, 1995.
DOI : 10.1016/0005-2760(95)00137-2

R. D. Duan and Å. Nilsson, [30] Sphingolipid hydrolyzing enzymes in the gastrointestinal tract, Methods Enzymol, vol.311, pp.276-286, 2000.
DOI : 10.1016/S0076-6879(00)11089-4

R. D. Duan, Y. Cheng, L. Yang, L. Ohlsson, and A. Nilsson, Evidence for specific ceramidase present in the intestinal contents of rats and humans, Lipids, vol.275, issue.8, pp.807-812, 2001.
DOI : 10.1007/s11745-001-0788-3

R. D. Duan, Y. Cheng, B. A. Jönsson, L. Ohlsson, A. Herbst et al., Human Meconium Contains Significant Amounts of Alkaline Sphingomyelinase, Neutral Ceramidase, and Sphingolipid Metabolites, Pediatric Research, vol.46, issue.1, pp.61-66, 2007.
DOI : 10.1203/01.pdr.0000250534.92934.c2

R. D. Duan and A. Nilsson, Metabolism of sphingolipids in the gut and its relation to inflammation and cancer development, Progress in Lipid Research, vol.48, issue.1, pp.62-72, 2009.
DOI : 10.1016/j.plipres.2008.04.003

N. O. Dündar, B. Dündar, G. Cesur, N. Yilmaz, R. Sütçu et al., Ghrelin and adiponectin levels in colostrum, cord blood and maternal serum, Pediatrics International, vol.27, issue.4, pp.622-625, 2010.
DOI : 10.1111/j.1442-200X.2010.03100.x

B. Dvorak, M. D. Halpern, H. Holubec, C. S. Williams, D. L. Mcwilliam et al., Epidermal growth factor reduces the development of necrotizing enterocolitis in a neonatal rat model, American Journal of Physiology - Gastrointestinal and Liver Physiology, vol.282, issue.1, pp.156-164, 2002.
DOI : 10.1152/ajpgi.00196.2001

B. Dvorak, C. C. Fituch, C. S. Williams, N. M. Hurst, and R. J. Schanler, Increased Epidermal Growth Factor Levels in Human Milk of Mothers with Extremely Premature Infants, Pediatric Research, vol.30, issue.1, pp.15-19, 2003.
DOI : 10.1203/01.PDR.0000065729.74325.71

B. Dvorak, Milk Epidermal Growth Factor and Gut Protection, The Journal of Pediatrics, vol.156, issue.2, pp.31-35
DOI : 10.1016/j.jpeds.2009.11.018

R. A. Ehrenkranz, Early nutritional support and outcomes in ELBW infants. Early Human Dev, pp.21-25, 2010.

E. Elass, M. Masson, J. Mazurier, and D. Legrand, Lactoferrin Inhibits the Lipopolysaccharide-Induced Expression and Proteoglycan-Binding Ability of Interleukin-8 in Human Endothelial Cells, Infection and Immunity, vol.70, issue.4, pp.1860-1866, 2002.
DOI : 10.1128/IAI.70.4.1860-1866.2002

URL : https://hal.archives-ouvertes.fr/hal-00149471

M. W. Elmlinger, F. Hochhaus, A. Loui, K. W. Frommer, M. Obladen et al., Insulin-Like Growth Factors and Binding Proteins in Early Milk from Mothers of Preterm and Term Infants, Hormone Research in Paediatrics, vol.68, issue.3, pp.68124-131, 2007.
DOI : 10.1159/000100488

U. Eriksson, G. Duc, E. R. Froesch, and J. Zapf, Insulin-like Growth Factors (IGF) I and II and IGF Binding Proteins (IGFBPs) in Human Colostrum/Transitory Milk During the 1st Week Postpartum: Comparison with Neonatal and Maternal Serum, Biochemical and Biophysical Research Communications, vol.196, issue.1, pp.267-273, 1993.
DOI : 10.1006/bbrc.1993.2244

J. B. Ewaschuk, H. Diaz, L. Meddings, B. Diederichs, A. Dmytrash et al., Secreted bioactive factors from Bifidobacterium infantis enhance epithelial cell barrier function, AJP: Gastrointestinal and Liver Physiology, vol.295, issue.5, pp.295-1025, 2008.
DOI : 10.1152/ajpgi.90227.2008

F. Facchinetti, M. Fazzio, and P. Venturini, Polyunsaturated fatty acids and risk of preterm delivery, Eur. Rev. Med. Pharmacol. Sci, vol.9, issue.1, pp.41-48, 2005.

S. Fanaro, R. Chierici, P. Guerrini, and V. Vigi, Intestinal microflora in early infancy: composition and development, Acta Paediatrica, vol.71, issue.Suppl, pp.48-55, 2003.
DOI : 10.1111/j.1651-2227.2003.tb00646.x

L. Fernández, S. Langa, V. Martin, E. Jiménez, R. Martin et al., The microbiota of human milk in healthy women, Cell. Mol. Biol, vol.2013, issue.591, pp.31-42

A. Fieker, J. Philpott, A. , and M. , Enzyme Replacement Therapy for Pancreatic Insufficiency: Present and Future, Clin. Exp. Gastroenterol, vol.4, pp.55-73, 2011.
URL : https://hal.archives-ouvertes.fr/inserm-00701598

C. J. Field, M. T. Clandinin, and J. E. Van-aerde, Polyunsaturated fatty acids and T-cell function: Implications for the neonate, Lipids, vol.17, issue.Suppl., pp.1025-1032, 2001.
DOI : 10.1007/s11745-001-0813-6

L. M. Freed, S. E. Berkow, P. Hamosh, C. M. York, N. R. Mehta et al., Lipases in human milk: effect of gestational age and length of lactation on enzyme activity., Journal of the American College of Nutrition, vol.3, issue.2, pp.143-150, 1989.
DOI : 10.1080/07315724.1989.10720289

S. Fukuda, H. Toh, K. Hase, K. Oshima, Y. Nakanishi et al., Bifidobacteria can protect from enteropathogenic infection through production of acetate, Nature, vol.37, issue.7331, pp.469543-547, 2011.
DOI : 10.1038/nature09646

O. Gabrielli, L. Zampini, T. Galeazzi, L. Padella, L. Santoro et al., Preterm Milk Oligosaccharides During the First Month of Lactation, PEDIATRICS, vol.128, issue.6, pp.1520-1531, 2011.
DOI : 10.1542/peds.2011-1206

C. Garcia, R. D. Duan, S. Confort-gouny, V. Millet, C. Gire et al., Consumption of bioactive molecules protecting from necrotising enterocolitis in premature newborns receiving native or pasteurised human milk French mothers' milk deficient in DHA contains phospholipid species of potential interest for infant development, Proc. Nutr. Soc. J. Pediatr. Gastroenterol. Nutr, vol.67, issue.53, pp.206-212, 2008.

C. Garcia, N. W. Lutz, S. Confort-gouny, P. J. Cozzone, M. Armand et al., Phospholipid fingerprints of milk from different animal species determined by 31 P NMR: towards specific interest in human health, Food Chem, vol.2012, issue.3, pp.1351777-1783

C. Garcia, V. Brévaut-malaty, V. Millet, R. D. Duan, C. Gire et al., Phospholipids composition of human milk determined by 31 P-NMR and relationship to intestinal maturity in premature neonates, MAGMA, vol.2013, issue.261

R. A. Gibson and G. M. Kneebone, Fatty acid composition of human colostrum and mature breast milk, Am. J. Clin. Nutr, vol.34, issue.2, pp.252-257, 1981.

M. P. Glauser, D. Heumann, J. D. Baumgartner, J. Cohen, M. M. Godlewski et al., Pathogenesis and potential strategies for prevention and treatment of septic shock: an update Into the unknown--the death pathways in the neonatal gut epithelium, Clin. Infect. Dis. J. Physiol. Pharmacol, vol.18, pp.567-591, 1994.

R. Goelz, E. Hihn, K. Hamprecht, K. Dietz, G. Jahn et al., Effects of Different CMV-Heat-Inactivation-Methods on Growth Factors in Human Breast Milk, Pediatric Research, vol.116, issue.4, pp.458-461, 2009.
DOI : 10.1203/PDR.0b013e3181991f18

A. S. Goldman, C. Garza, B. L. Nichols, and R. M. Goldblum, Immunologic factors in human milk during the first year of lactation, The Journal of Pediatrics, vol.100, issue.4, pp.563-567, 1982.
DOI : 10.1016/S0022-3476(82)80753-1

A. S. Goldman, C. Garza, B. Nichols, C. A. Johnson, E. O. Smith et al., Effects of prematurity on the immunologic system in human milk, The Journal of Pediatrics, vol.101, issue.6, pp.901-905, 1982.
DOI : 10.1016/S0022-3476(82)80007-3

S. Groh-wargo and A. Sapsford, Enteral Nutrition Support of the Preterm Infant in the Neonatal Intensive Care Unit, Nutrition in Clinical Practice, vol.24, issue.3, pp.363-376, 2009.
DOI : 10.1177/0884533609335310

S. J. Gross, Growth and Biochemical Response of Preterm Infants Fed Human Milk or Modified Infant Formula, New England Journal of Medicine, vol.308, issue.5, pp.237-241, 1983.
DOI : 10.1056/NEJM198302033080501

M. Gueimonde, K. Laitinen, S. Salminen, and E. Isolauri, Breast Milk: A Source of Bifidobacteria for Infant Gut Development and Maturation?, Neonatology, vol.92, issue.1, pp.64-66, 2007.
DOI : 10.1159/000100088

H. H. Habte, G. J. Kotwal, Z. E. Lotz, M. G. Tyler, M. Abrahams et al., Antiviral Activity of Purified Human Breast Milk Mucin, Neonatology, vol.92, issue.2, pp.96-104, 2007.
DOI : 10.1159/000100808

M. Hamosh, J. A. Peterson, T. R. Henderson, C. D. Scallan, R. Kivan et al., Protective function of human milk: The milk fat globule, Seminars in Perinatology, vol.23, issue.3, pp.242-249, 1999.
DOI : 10.1016/S0146-0005(99)80069-X

L. A. Hanson and M. Korotkova, The role of breastfeeding in prevention of neonatal infection, Seminars in Neonatology, vol.7, issue.4, pp.275-281, 2002.
DOI : 10.1016/S1084-2756(02)90124-7

E. Harada and B. Syuto, Precocious cessation of intestinal macromolecular transmission and sucrase development induced by insulin in adrenalectomized suckling rat, Comparative Biochemistry and Physiology Part A: Physiology, vol.99, issue.3, pp.327-331, 1991.
DOI : 10.1016/0300-9629(91)90009-2

N. L. Harris, I. Spoerri, J. F. Schopfer, C. Nembrini, P. Merky et al., Mechanisms of Neonatal Mucosal Antibody Protection, The Journal of Immunology, vol.177, issue.9, pp.1776256-6262, 2006.
DOI : 10.4049/jimmunol.177.9.6256

M. P. Heikkila and P. E. Saris, Inhibition of Staphylococcus aureus by the commensal bacteria of human milk, Journal of Applied Microbiology, vol.64, issue.3, pp.471-478, 2003.
DOI : 10.1016/S0928-8244(99)00077-2

J. J. Henderson, O. A. Mcwilliam, J. P. Newnham, and C. E. Pennell, Maternal factors associated with three phenotypes: spontaneous preterm labour, preterm pre-labour rupture of membranes and medically indicated preterm birth, J. Matern, 2004.

O. Hernell, H. Ward, L. Bläckberg, and M. E. Pereira, Killing of Giardia lamblia by Human Milk Lipases: An Effect Mediated by Lipolysis of Milk Lipids, Journal of Infectious Diseases, vol.153, issue.4, pp.715-720, 1986.
DOI : 10.1093/infdis/153.4.715

O. Hernell, L. Bläckberg, Q. Chen, B. Sternby, and A. Nilsson, Does the Bile Salt-Stimulated Lipase of Human Milk Have a Role in the Use of the Milk Long-Chain Polyunsaturated Fatty Acids?, Journal of Pediatric Gastroenterology and Nutrition, vol.16, issue.4, pp.426-431, 1993.
DOI : 10.1097/00005176-199305000-00014

J. M. Hodek, J. M. Von-der-schulenburg, and T. Mittendorf, Measuring economic consequences of preterm birth - Methodological recommendations for the evaluation of personal burden on children and their caregivers, Health Economics Review, vol.1, issue.1, pp.6-7, 2011.
DOI : 10.1046/j.1524-4733.2003.00220.x

B. Hornung, E. Amtmann, and G. Sauer, Lauric acid inhibits the maturation of vesicular stomatitis virus, Journal of General Virology, vol.75, issue.2, pp.75353-361, 1994.
DOI : 10.1099/0022-1317-75-2-353

V. M. Houle, E. A. Schroeder, J. Odle, and S. M. Donovan, Small Intestinal Disaccharidase Activity and Ileal Villus Height Are Increased in Piglets Consuming Formula Containing Recombinant Human Insulin-Like Growth Factor-I, Pediatric Research, vol.146, issue.1, pp.78-86, 1997.
DOI : 10.1203/00006450-199707000-00013

V. M. Houle, Y. K. Park, S. C. Laswell, G. G. Freund, M. A. Dudley et al., Investigation of Three Doses of Oral Insulin-like Growth Factor-I on Jejunal Lactase Phlorizin Hydrolase Activity and Gene Expression and Enterocyte Proliferation and Migration in Piglets, Pediatric Research, vol.47, issue.4, pp.497-503, 2000.
DOI : 10.1203/00006450-200010000-00013

K. L. Houseknecht, M. K. Mcguire, C. P. Portocarrero, M. A. Mcguire, and K. Beerman, Leptin Is Present in Human Milk and Is Related to Maternal Plasma Leptin Concentration and Adiposity, Biochemical and Biophysical Research Communications, vol.240, issue.3
DOI : 10.1006/bbrc.1997.7736

P. N. Howles, G. N. Stemmerman, C. M. Fenoglio-preiser, and D. Y. Hui, Carboxyl ester lipase activity in milk prevents fat-derived intestinal injury in neonatal mice, Am. J. Physiol. Gastrointest. Liver Physiol, vol.277, issue.3, pp.653-661, 1999.

Y. O. Ilcol, Z. B. Hizli, and E. Eroz, Resistin is present in human breast milk and it correlates with maternal hormonal status and serum level of C-reactive protein, Clinical Chemistry and Laboratory Medicine, vol.46, issue.1, pp.118-124, 2008.
DOI : 10.1515/CCLM.2008.019

S. M. Innis, Perinatal biochemistry and physiology of long-chain polyunsaturated fatty acids, The Journal of Pediatrics, vol.143, issue.4, pp.1-8, 2003.
DOI : 10.1067/S0022-3476(03)00396-2

C. E. Isaacs, H. Thormar, and T. Pessolano, Membrane-Disruptive Effect of Human Milk: Inactivation of Enveloped Viruses, Journal of Infectious Diseases, vol.154, issue.6, pp.966-971, 1986.
DOI : 10.1093/infdis/154.6.966

C. E. Isaacs, R. E. Litov, and H. Thormar, Antimicrobial activity of lipids added to human milk, infant formula, and bovine milk, The Journal of Nutritional Biochemistry, vol.6, issue.7, pp.362-366, 1995.
DOI : 10.1016/0955-2863(95)80003-U

S. Ishizeki, M. Sugita, M. Takata, and T. Yaeshima, Effect of administration of bifidobacteria on intestinal microbiota in??low-birth-weight infants and transition of administered bifidobacteria: A comparison between one-species and three-species administration, Anaerobe, vol.23, pp.38-44, 2013.
DOI : 10.1016/j.anaerobe.2013.08.002

T. Jilling, D. Simon, J. Lu, F. J. Meng, D. Li et al., The Roles of Bacteria and TLR4 in Rat and Murine Models of Necrotizing Enterocolitis, The Journal of Immunology, vol.177, issue.5, pp.1773273-3282, 2006.
DOI : 10.4049/jimmunol.177.5.3273

K. Johnson, L. Ross, R. Miller, X. Xiao, and M. E. Lowe, Pancreatic lipase???related protein 2 digests fats in human milk and formula in concert with gastric lipase and carboxyl ester lipase, Pediatric Research, vol.91, issue.2, pp.74127-132
DOI : 10.1111/j.1432-1033.1991.tb16346.x

J. J. Kabara, D. M. Swieczkowski, A. J. Conley, and J. P. Truant, Fatty Acids and Derivatives as Antimicrobial Agents, Antimicrobial Agents and Chemotherapy, vol.2, issue.1, pp.23-28, 1972.
DOI : 10.1128/AAC.2.1.23

J. A. Kierson, D. M. Dimatteo, and R. G. Locke, Ghrelin and cholecystokinin in term and preterm human breast milk, Acta Paediatrica, vol.1, issue.8, pp.95991-995, 2006.
DOI : 10.1126/science.1117255

C. J. Klein, W. C. Heird, N. D. Embleton, S. E. Jacobs, L. A. O-'connell et al., Summary and comparison of recommendations for nutrient contents of low-birth-weight infant formulas. Life Siences Research Office Enteral feeding practices in very preterm infants: an international survey, Arch. Dis. Child Fetal Neonatal Ed, vol.2012, issue.971, pp.56-61

N. Kosaka, H. Izumi, K. Sekine, and T. Ochiya, microRNA as a new immune-regulatory agent in breast milk Late preterm infants: near term but still in a critical developmental time period, Silence Pediatrics, vol.2010, issue.1324, pp.741-751

A. Kumral, H. Ozkan, N. Duman, D. C. Yesilirmak, H. Islekel et al., Breast Milk Jaundice Correlates With High Levels of Epidermal Growth Factor, Pediatric Research, vol.39, issue.2, pp.66218-221, 2009.
DOI : 10.1203/PDR.0b013e3181ac4a30

M. O. Labéta, K. Vidal, J. E. Nores, M. Arias, N. Vita et al., Innate recognition of bacteria in human milk is mediated by a milk-derived highly expressed pattern recognition receptor, soluble CD14 Breast milk fatty acids may link innate and adaptive immune regulation: analysis of soluble CD14, prostaglandin E-2, and fatty acids Postnatal docosahexaenoic acid deficiency is an inevitable consequence of current recommendations and practice in preterm infants, J. Exp. Med. Pediatr. Res. Neonatology, vol.191, issue.98, pp.1807-1812723, 2000.

A. Lapillonne, S. Groh-wargo, C. H. Gonzalez, and R. Uauy, Lipid Needs of Preterm Infants: Updated Recommendations, The Journal of Pediatrics, vol.162, issue.3, pp.37-47
DOI : 10.1016/j.jpeds.2012.11.052

E. Lattka, P. Rzehak, É. Szabó, V. Jakobik, M. Weck et al., Genetic variants in the FADS gene cluster are associated with arachidonic acid concentrations of human breast milk at 1.5 and 6 mo postpartum and influence the course of milk dodecanoic, tetracosenoic, and trans-9-octadecenoic acid concentrations over the duration of lactation, .P. and Labéta, M.O., Soluble forms of Toll-like receptor (TLR)2, pp.382-391, 2011.
DOI : 10.3945/ajcn.110.004515

E. Rey-nores, J. E. Raby, A. C. Affolter, M. Vidal, K. Thornton et al., Modulation of neonatal microbial recognition: TLR-mediated innate immune responses are specifically and differentially modulated by human milk Pinyo- A u t h o r s v e r s i o n pasakul, capable of modulating TLR2 signaling are present in human plasma and breast milk Kido, N. and Inukai S., Comparison of the protein composition of breast milk and the nutrient intake between Thai and Japanese mothers, pp.6680-66893742, 2003.

D. Legrand and J. Mazurier, A critical review of the roles of host lactoferrin in immunity, BioMetals, vol.144, issue.3, pp.365-376, 2010.
DOI : 10.1007/s10534-010-9297-1

URL : https://hal.archives-ouvertes.fr/hal-00469788

Y. Liao and B. Lönnerdal, miR-584 mediates post-transcriptional expression of lactoferrin receptor in Caco-2 cells and in mouse small intestine during the perinatal period, The International Journal of Biochemistry & Cell Biology, vol.42, issue.8, pp.421363-1369, 2010.
DOI : 10.1016/j.biocel.2009.07.019

Y. Liao, R. Jiang, and B. Lönnerdal, Biochemical and molecular impacts of lactoferrin on small intestinal growth and development during early life, Biochem. Cell Biol, vol.2012, issue.903, pp.476-484

C. Liepke, K. Adermann, M. Raida, H. J. Mägert, W. G. Forssmann et al., Human milk provides peptides highly stimulating the growth of bifidobacteria, European Journal of Biochemistry, vol.27, issue.2, pp.712-718, 2002.
DOI : 10.1046/j.0014-2956.2001.02712.x

J. Lillienau, Y. Cheng, A. Nilsson, and R. D. Duan, Development of intestinal alkaline sphingomyelinase in rat fetus and newborn rat, Lipids, vol.256, issue.5, pp.545-549, 2003.
DOI : 10.1007/s11745-003-1340-1

H. C. Lin, B. H. Su, A. C. Chen, T. W. Lin, C. Tsai et al., Oral Probiotics Reduce the Incidence and Severity of Necrotizing Enterocolitis in Very Low Birth Weight Infants, Pediatrics, vol.115, issue.1, pp.1-4, 2005.
DOI : 10.1542/peds.2004-1463

B. Liu, Z. Yu, C. Chen, D. E. Kling, and D. S. Newburg, Human Milk Mucin 1 and Mucin 4 Inhibit Salmonella enterica Serovar Typhimurium Invasion of Human Intestinal Epithelial Cells In Vitro, Journal of Nutrition, vol.142, issue.8, pp.1421504-1509
DOI : 10.3945/jn.111.155614

J. M. López-pedrosa, M. Ramírez, M. I. Torres, and A. Gil, Dietary phospholipids rich in long-chain polyunsaturated fatty acids improve the repair of small intestine in previously malnourished piglets, J. Nutr, issue.6, pp.1291149-1155, 1999.

M. Lotz, D. Gütle, S. Walther, S. Menard, C. Bogdan et al., Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells, The Journal of Experimental Medicine, vol.270, issue.4, pp.973-984, 2006.
DOI : 10.1073/pnas.0401710101

M. E. Lowe, The triglyceride lipases of the pancreas, The Journal of Lipid Research, vol.43, issue.12, pp.2007-2016, 2002.
DOI : 10.1194/jlr.R200012-JLR200

A. Lucas and T. J. Cole, Breast milk and neonatal necrotising enterocolitis, The Lancet, vol.336, issue.8730-8731, pp.1519-1523, 1990.
DOI : 10.1016/0140-6736(90)93304-8

L. Ma and R. J. Xu, Oral insulin like growth factor-I stimulates intestinal enzyme maturation in newborn rats, Life Sci, issue.1, pp.6151-58, 1997.

R. Maestre, J. D. Douglass, S. Kodukula, I. Medina, and J. Storch, Alterations in the Intestinal Assimilation of Oxidized PUFAs Are Ameliorated by a Polyphenol-Rich Grape Seed Extract in an In Vitro Model and Caco-2 Cells, Journal of Nutrition, vol.143, issue.3, pp.143295-301
DOI : 10.3945/jn.112.160101

L. Maggio, M. Bellagamba, S. Costa, C. Romagnoli, M. Rodriguez et al., A prospective, randomized , double-blind crossover study comparing rhBSSL (recombinant human Bile Salt Stimulated Lipase) and placebo added to infant formula during one week of treatment in preterm infants born before 32 weeks of gestational age

P. Manzoni, L. Decembrino, I. Stolfi, L. Pugni, M. Rinaldi et al., and Italian Task Force for the Study and Prevention of Neonatal Fungal Infections, Italian Society of Neonatology, Lactoferrin and prevention of late-onset sepsis in the pre-term neonates, Early Hum. Dev, pp.8659-61, 2010.

R. Martin, S. Langa, C. Reviriego, E. Jimenez, M. L. Marin et al., Human milk is a source of lactic acid bacteria for the infant gut, The Journal of Pediatrics, vol.143, issue.6, pp.754-758, 2003.
DOI : 10.1016/j.jpeds.2003.09.028

R. Martin, M. Olivares, M. L. Marin, L. Fernandez, J. Xaus et al., Probiotic Potential of 3 Lactobacilli Strains Isolated From Breast Milk, Journal of Human Lactation, vol.101, issue.1, pp.8-17, 2005.
DOI : 10.1177/0890334404272393

L. J. Martin, J. G. Woo, S. R. Geraghty, M. Altaye, B. S. Davidson et al., Adiponectin is present in human milk and is associated with maternal factors, Am. J. Clin. Nutr, issue.5, pp.831106-1111, 2006.

R. Martin, H. G. Heilig, E. G. Zoetendal, E. Jimenez, L. Fernandez et al., Cultivation-independent assessment of the bacterial diversity of breast milk among healthy women, Research in Microbiology, vol.158, issue.1, pp.31-37, 2007.
DOI : 10.1016/j.resmic.2006.11.004

R. Martin, H. G. Heilig, E. G. Zoetendal, H. Smidt, and J. M. Rodriguez, Diversity of the Lactobacillus group in breast milk and vagina of healthy women and potential role in the colonization of the infant gut, Journal of Applied Microbiology, vol.64, issue.6, pp.2638-2644, 2007.
DOI : 10.1111/j.1365-2672.2007.03497.x

R. Martin, E. Jimenez, H. Heilig, L. Fernandez, M. L. Marin et al., Isolation of Bifidobacteria from Breast Milk and Assessment of the Bifidobacterial Population by PCR-Denaturing Gradient Gel Electrophoresis and Quantitative Real-Time PCR, Applied and Environmental Microbiology, vol.75, issue.4, pp.965-969, 2009.
DOI : 10.1128/AEM.02063-08

B. H. Maskrey, I. L. Megson, A. G. Rossi, and P. D. Whitfield, Emerging importance of omega-3 fatty acids in the innate immune response: Molecular mechanisms and lipidomic strategies for their analysis, Molecular Nutrition & Food Research, vol.135, issue.Suppl 5, pp.571390-1400
DOI : 10.1002/mnfr.201200723

T. Matsuki, K. Watanabe, and R. Tanaka, Genus-and species-specific PCR primers for the detection and identification of bifidobacteria, Curr. Issues Intest. Microbiol, vol.4, issue.2, pp.61-69, 2003.

R. T. Maxson, R. J. Jackson, and S. D. Smith, The protective role of enteral IgA supplementation in neonatal gut origin sepsis, Journal of Pediatric Surgery, vol.30, issue.2, pp.231-233, 1995.
DOI : 10.1016/0022-3468(95)90566-9

A. A. Maynard, K. Dvorak, L. Khailova, H. Dobrenen, K. M. Arganbright et al., Epidermal growth factor reduces autophagy in intestinal epithelium and in the rat model of necrotizing enterocolitis Toll-Like Receptor mRNA Expression Is Selectively Increased in the Colonic Mucosa of Two Animal Models Relevant to Irritable Bowel Syndrome, G614-G622. 161. McKernan, p.8226, 2009.

R. Mehta and A. Petrova, Biologically active breast milk proteins in association with very preterm delivery and stage of lactation, Journal of Perinatology, vol.13, issue.1, pp.3158-62, 2011.
DOI : 10.1006/bbrc.1999.0255

D. Ménard, L. Corriveau, and J. F. Beaulieu, Insulin Modulates Cellular Proliferation in Developing Human Jejunum and Colon, Neonatology, vol.75, issue.3, pp.143-151, 1999.
DOI : 10.1159/000014090

C. Messerlian, L. Maclagan, O. Basso, P. J. Miettinen, ;. J. Berger et al., Infertility and the risk of adverse pregnancy outcomes: a systematic review and meta-analysis Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor Dietary ganglioside reduces proinflammatory signaling in the intestine, Hum. Reprod. Nature J Nutr Metab, vol.2013, issue.2012, pp.125-137337, 1995.

S. R. Milsom, W. F. Blum, A. J. Gunn, J. Sanchez, A. Palou et al., Temporal Changes in Insulin-Like Growth Factors I and II and in Insulin-Like Growth Factor Binding Proteins 1, 2, and 3 in Human Milk, Hormone Research, vol.69, issue.5, pp.307-311, 2006.
DOI : 10.1159/000114863

C. Moltó-puigmartí, J. Plat, R. P. Mensink, A. Müller, E. Jansen et al., FADS1 FADS2 gene variants modify the association between fish intake and the docosahexaenoic acid proportions in human milk, American Journal of Clinical Nutrition, vol.91, issue.5, pp.911368-1376, 2010.
DOI : 10.3945/ajcn.2009.28789

C. Moltó-puigmartí and A. I. Castellote, Carbonell-Estrany, X. and A u t h o r s v e r s i o n

M. C. López-sabater, Differences in fat content and fatty acid proportions among colostrum, transitional, and mature milk from women delivering very preterm, preterm, and term infants, Clin. Nutr, vol.30, issue.1, pp.116-123, 2011.

P. M. Montagne, V. S. Tregoat, M. L. Cuilliere, M. C. Béné, and G. C. Faure, Measurement of nine human milk proteins by nephelometric immunoassays: application to the determination of mature milk protein profile, Clinical Biochemistry, vol.33, issue.3, pp.33181-186, 2000.
DOI : 10.1016/S0009-9120(00)00059-X

A. Moschetta, G. P. Vanberge-henegouwen, P. Portincasa, G. Palasciano, A. K. Groen et al., Sphingomyelin exhibits greatly enhanced protection compared with egg yolk phosphatidylcholine against detergent bile salts, J. Lipid Res, issue.6, pp.41916-924, 2000.

M. Motouri, H. Matsuyama, J. I. Yamamura, M. Tanaka, S. Aoe et al., Milk Sphingomyelin Accelerates Enzymatic and Morphological Maturation of the Intestine in Artificially Reared Rats, Journal of Pediatric Gastroenterology and Nutrition, vol.36, issue.2, pp.241-247, 2003.
DOI : 10.1097/00005176-200302000-00016

E. M. Munch, R. A. Harris, M. Mohammad, A. L. Benham, S. M. Pejerrey et al., Transcriptome Profiling of microRNA by Next-Gen Deep Sequencing Reveals Known and Novel miRNA Species in the Lipid Fraction of Human Breast Milk, PLoS ONE, vol.5, issue.2, p.50564, 2013.
DOI : 10.1371/journal.pone.0050564.s002

A. Murasugi, Y. Asami, and Y. Mera-kikuchi, Production of Recombinant Human Bile Salt-Stimulated Lipase in Pichia pastoris, Protein Expression and Purification, vol.23, issue.2, pp.282-288, 2001.
DOI : 10.1006/prep.2001.1509

T. Murguía-peniche, W. A. Mihatsch, J. Zegarra, S. Supapannachart, Z. Y. Ding et al., Intestinal Mucosal Defense System, Part 2. Probiotics and Prebiotics, The Journal of Pediatrics, vol.162, issue.3, pp.162-64
DOI : 10.1016/j.jpeds.2012.11.055

N. N. Nanthakumar, R. D. Fusunyan, I. Sanderson, and W. A. Walker, Inflammation in the developing human intestine: A possible pathophysiologic contribution to necrotizing enterocolitis, Proc. Natl
DOI : 10.1073/pnas.97.11.6043

J. Neu, W. R. Walker, E. L. Engelhardt, C. Y. Wu-wang, M. B. Roa et al., Alterations in Piglet Small Intestine after Cholesterol Deprivation, Pediatric Research, vol.22, issue.3, pp.22330-334, 1987.
DOI : 10.1203/00006450-198709000-00018

D. S. Newburg, G. M. Ruiz-palacios, and A. L. Morrow, HUMAN MILK GLYCANS PROTECT INFANTS AGAINST ENTERIC PATHOGENS, Annual Review of Nutrition, vol.25, issue.1, pp.37-58, 2005.
DOI : 10.1146/annurev.nutr.25.050304.092553

M. Nishimukai, T. Wakisaka, and H. Hara, Ingestion of plasmalogen markedly increased plasmalogen levels of blood plasma in rats, Lipids, vol.1437, issue.12, pp.1227-1735, 2003.
DOI : 10.1007/s11745-003-1183-9

T. Nojiri, T. Yoshizato, T. Fukami, H. Obama, H. Yagi et al., Clinical significance of amphiregulin and epidermal growth factor in colostrum, Archives of Gynecology and Obstetrics, vol.36, issue.3, pp.286643-647
DOI : 10.1007/s00404-012-2365-8

L. Nyberg, A. Farooqi, L. Blackberg, R. D. Duan, A. Nilsson et al., Digestion of Ceramide by Human Milk Bile Salt-Stimulated Lipase, Journal of Pediatric Gastroenterology & Nutrition, vol.27, issue.5, pp.27560-567, 1998.
DOI : 10.1097/00005176-199811000-00013

O. O. Ogunwobi and I. L. Beales, Adiponectin stimulates proliferation and cytokine secretion in colonic epithelial cells, Regulatory Peptides, vol.134, issue.2-3, pp.105-113, 2006.
DOI : 10.1016/j.regpep.2006.02.001

R. Oozeer, K. Van-limpt, T. Ludwig, B. Amor, K. Martin et al., Intestinal microbiology in early life: specific prebiotics can have similar functionalities as human-milk oligosaccharides, American Journal of Clinical Nutrition, vol.98, issue.2, pp.98561-571
DOI : 10.3945/ajcn.112.038893

A. Oslislo, Z. Czuba, H. Slawska, W. Ka?mierczak, and W. Król, Decreased Human Milk Concentration of Epidermal Growth Factor After Preterm Delivery of Intrauterine Growth-restricted Newborns, Journal of Pediatric Gastroenterology and Nutrition, vol.44, issue.4, pp.464-467, 2007.
DOI : 10.1097/MPG.0b013e3180331e15

T. Ozgurtas, I. Aydin, O. Turan, E. Koc, I. M. Hirfanoglu et al., Vascular endothelial growth factor, basic fibroblast growth factor, insulin-like growth factor-I and platelet-derived growth factor levels in human milk of mothers with term and preterm neonates, Cytokine, vol.50, issue.2, pp.192-194, 2010.
DOI : 10.1016/j.cyto.2010.02.008

S. Patton, S. J. Gendler, and A. P. Spicer, The epithelial mucin, MUC1, of milk, mammary gland and other tissues, Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, vol.1241, issue.3, pp.1241407-423, 1995.
DOI : 10.1016/0304-4157(95)00014-3

P. F. Perez, J. Doré, M. Leclerc, F. Levenez, J. Benyacoub et al., Bacterial imprinting of the neonatal immune system: lessons from maternal cells ? Pediatrics Maintenance of breast milk Immunoglobulin A after high-pressure processing, J. Dairy Sci, vol.119, issue.3, pp.724-732, 2007.

J. A. Peterson, T. R. Henderson, M. Hamosh, C. Scallen, R. Kivan et al., Milk Fat Globule Glycoproteins in Human Milk and in Gastric Aspirates of Mother's Milk-Fed Preterm Infants, Pediatric Research, vol.74, issue.4, pp.499-506, 1998.
DOI : 10.1203/00006450-199810000-00006

C. T. Phan, P. Tso, A. F. Philipps, G. G. Anderson, B. Dvorák et al., Growth of artificially fed infant rats: effect of supplementation with insulin-like growth factor I Characterization of the bactericidal effect of dietary sphingosine and its activity under intestinal conditions Supplementation with Lactobacillus rhamnosus or Bifidobacterium lactis probiotics in pregnancy increases cord blood interferon-gamma and breast milk transforming growth factor-beta and immunoglobin A detection Human proteome enhancement: high-recovery method and improved two-dimensional map of colostral fat globule membrane proteins, Pt 2):R1532-R1539. 193. Possemiers, pp.299-31959, 1997.

P. S. Ranade, S. S. Rao, R. R. Maternal-diet-ran-ressler, L. Khailova, K. M. Arganbright et al., LCPUFA status and prematurity in indian mothers: A cross-sectional study Branched chain fatty acids reduce the incidence of necrotizing enterocolitis and alter gastrointestinal microbial ecology in a neonatal rat modelE8 : a bi-motif protein that orchestrates diverse cellular interactions, PLoS One J. Cell Biochem, vol.2, issue.1066, pp.414-427957, 2009.

M. Resto, D. O-'connor, K. Leef, V. Funanage, M. Spear et al., Leptin levels in preterm human breast milk and infant formula Supplementation of an adapted formula with bovine lactoferrin: 1. Effect on the infant faecal flora, Pediatrics Acta Paediatr, vol.108, issue.12, pp.81119-124, 1992.

S. Ruiz-moyano, S. M. Totten, D. A. Garrido, J. T. Smilowitz, J. B. German et al., Variation in Consumption of Human Milk Oligosaccharides by Infant Gut-Associated Strains of Bifidobacterium breve, Applied and Environmental Microbiology, vol.79, issue.19, pp.796040-6049
DOI : 10.1128/AEM.01843-13

N. Ruvoën-clouet, E. Mas, S. Marionneau, P. Guillon, D. Lombardo et al., Bile-salt-stimulated lipase and mucins from milk of ???secretor??? mothers inhibit the binding of Norwalk virus capsids to their carbohydrate ligands, Biochemical Journal, vol.393, issue.3, pp.393627-634, 2006.
DOI : 10.1042/BJ20050898

F. Savino, S. Benetti, M. M. Lupica, E. Petrucci, E. Palumeri et al., Ghrelin and obestatin in infants, lactating A u t h o r s v e r s i o n mothers and breast milk, Horm. Res. Paediatr, vol.78, pp.5-6297, 2012.

F. Savino, M. Sorrenti, S. Benetti, M. M. Lupica, S. A. Liguori et al., Resistin and leptin in breast milk and infants in early life, Early Human Development, vol.88, issue.10, pp.88779-782
DOI : 10.1016/j.earlhumdev.2012.05.004

F. Savino, M. M. Lupica, S. Benetti, E. Petrucci, S. A. Liguori et al., Adiponectin in breast milk: relation to serum adiponectin concentration in lactating mothers and their infants, Acta Paediatrica, vol.71, issue.Suppl 1, pp.1011058-1062
DOI : 10.1111/j.1651-2227.2012.02744.x

R. J. Schanler, R. J. Shulman, and C. Lau, Feeding Strategies for Premature Infants: Beneficial Outcomes of Feeding Fortified Human Milk Versus Preterm Formula, PEDIATRICS, vol.103, issue.6, pp.1150-1157, 1999.
DOI : 10.1542/peds.103.6.1150

R. J. Schanler, C. Lau, N. M. Hurst, and E. O. Smith, Randomized Trial of Donor Human Milk Versus Preterm Formula as Substitutes for Mothers' Own Milk in the Feeding of Extremely Premature Infants, PEDIATRICS, vol.116, issue.2, pp.400-406, 2005.
DOI : 10.1542/peds.2004-1974

H. Schroten, F. G. Hanisch, R. Plogmann, J. Hacker, G. Uhlenbruck et al., Inhibition of adhesion of Sfimbriated Escherichia coli to buccal epithelial cells by human milk fat globule membrane components: a novel aspect of the protective function of mucins in the nonimmunoglobulin fraction, Infect. Immun, issue.7, pp.602893-2899, 1992.

H. Schroten, M. Bosch, R. Nobis-bosch, H. Köhler, F. G. Hanisch et al., Secretory Immunoglobulin A Is a Component of the Human Milk Fat Globule Membrane, Pediatric Research, vol.50, issue.1, pp.82-86, 1999.
DOI : 10.1203/00006450-199901000-00014

C. N. Serhan, N. Chiang, and T. E. Van-dyke, Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators, Nature Reviews Immunology, vol.13, issue.5, pp.349-361, 2008.
DOI : 10.1038/nri2294

C. N. Serhan and N. Chiang, Resolution phase lipid mediators of inflammation: agonists of resolution, Current Opinion in Pharmacology, vol.13, issue.4, pp.632-640
DOI : 10.1016/j.coph.2013.05.012

R. Shamir and N. Shehadeh, Insulin in Human Milk and the Use of Hormones in Infant Formulas, Nestle Nutr. Inst. Workshop Ser, vol.77, pp.57-64, 2013.
DOI : 10.1159/000351384

N. Shehadeh, L. Gelertner, S. Blazer, R. Perlman, L. Solovachik et al., Importance of insulin content in infant diet: suggestion for a new infant formula, Acta Paediatrica, vol.356, issue.1, pp.9093-95, 2001.
DOI : 10.1111/j.1651-2227.2001.tb00262.x

N. Shehadeh, E. Kjaesh-goldberg, R. Shamir, R. Perlman, P. Sujov et al., Insulin in human milk: postpartum changes and effect of gestational age, Archives of Disease in Childhood - Fetal and Neonatal Edition, vol.88, issue.3
DOI : 10.1136/fn.88.3.F214

N. Shehadeh, I. Sukhotnik, and R. Shamir, Gastrointestinal Tract as a Target Organ for Orally Administered Insulin, Journal of Pediatric Gastroenterology and Nutrition, vol.43, issue.3, pp.276-281, 2006.
DOI : 10.1097/01.mpg.0000226377.03247.fb

H. Shoji, T. Shimizu, N. Kaneko, K. Shinohara, S. Shiga et al., Comparison of the phospholipid classes in human milk in Japanese mothers of term and preterm infants, Acta Paediatrica, vol.37, issue.8, pp.95996-1000, 2006.
DOI : 10.1097/00005176-200302000-00016

R. J. Shulman, Oral Insulin Increases Small Intestinal Mass and Disaccharidase Activity in the Newborn Miniature Pig, Pediatric Research, vol.28, issue.2, pp.171-175, 1990.
DOI : 10.1203/00006450-199008000-00018

R. J. Shulman, R. J. Schanler, C. Lau, M. Heitkemper, C. N. Ou et al., Early Feeding, Antenatal Glucocorticoids, and Human Milk Decrease Intestinal Permeability in Preterm Infants, Pediatric Research, vol.6, issue.4, pp.519-523, 1998.
DOI : 10.1203/00006450-199810000-00009

J. T. Smilowitz, A. O-'sullivan, D. Barile, J. B. German, B. Lönnerdal et al., The Human Milk Metabolome Reveals Diverse Oligosaccharide Profiles, Journal of Nutrition, vol.143, issue.11, pp.1431709-1718
DOI : 10.3945/jn.113.178772

S. M. Smith-kirwin, D. M. O-'connor, J. De-johnsto, E. D. Lancey, S. G. Hassink et al., Leptin Expression in Human Mammary Epithelial Cells and Breast Milk, The Journal of Clinical Endocrinology & Metabolism, vol.83, issue.5, pp.831810-1813, 1998.
DOI : 10.1210/jcem.83.5.4952

W. J. Spencer, A. Binette, T. L. Ward, L. Davis, D. R. Blais et al., Alpha-Lactalbumin in Human Milk Alters the Proteolytic Degradation of Soluble CD14 by Forming a Complex, Pediatric Research, vol.15, issue.6, pp.68490-493, 2010.
DOI : 10.1203/PDR.0b013e3181f70f21

C. Staedel and F. Darfeuille, MicroRNAs and bacterial infection, Cellular Microbiology, vol.7, issue.9, pp.1496-1507
DOI : 10.1111/cmi.12159

B. J. Stoll, N. Hansen, A. A. Fanaroff, L. L. Wright, W. A. Carlo et al., Late-Onset Sepsis in Very Low Birth Weight Neonates: The Experience of the NICHD Neonatal Research Network, PEDIATRICS, vol.110, issue.2, pp.285-291, 2002.
DOI : 10.1542/peds.110.2.285

S. Lindholm, E. Strandvik, B. Altman, D. Möller, A. et al., Different fatty acid pattern in breast milk of obese compared to normal-weight mothers Naturally occurring variants of human milk bile salt-stimulated lipase, Prostaglandins Leukot. Essent. Fatty Acids Arch. Biochem. Biophys, vol.2013, issue.3471, pp.211-21730, 1997.

A. M. Suikkari, J. S. Swan, M. M. Hoffman, M. K. Lord, and J. Poechmann, Insulin-like growth factor (IGF-I) and its low molecular weight binding protein in human milk, European Journal of Obstetrics & Gynecology and Reproductive Biology, vol.30, issue.1, pp.19-25119, 1989.
DOI : 10.1016/0028-2243(89)90089-0

S. Thurl, M. Munzert, J. Henker, G. Boehm, B. Müller-werner et al., Variation of human milk oligosaccharides in relation to milk groups and lactational periods, British Journal of Nutrition, vol.1, issue.09, pp.1261-1271, 2010.
DOI : 10.1016/j.abb.2004.01.023

F. Turroni, F. Bottacini, E. Foroni, I. Mulder, J. H. Kim et al., Genome analysis of Bifidobacterium bifidum PRL2010 reveals metabolic pathways for host-derived glycan foraging, Proc. Natl. Acad. Sci. U S A, pp.10719514-19519, 2010.
DOI : 10.1073/pnas.1011100107

R. Uauy, P. Mena, B. Wegher, S. Nieto, N. Salem et al., Long Chain Polyunsaturated Fatty Acid Formation in Neonates: Effect of Gestational Age and Intrauterine Growth, Pediatric Research, vol.45, issue.1, pp.127-135998, 2000.
DOI : 10.1203/00006450-200001000-00022

P. Valenti and G. Antonini, Lactoferrin, Cellular and Molecular Life Sciences, vol.62, issue.22, pp.622576-2587, 2005.
DOI : 10.1007/s00018-005-5372-0

K. Vidal, M. O. Labeta, E. J. Schiffrin, and A. Donnet-hugues, Soluble CD14 in human breast milk and its role in innate immune responses, Acta Odontologica Scandinavica, vol.29, issue.5, pp.330-334, 2001.
DOI : 10.1172/JCI2338

C. L. Wagner, S. N. Taylor, and D. Johnson, Host Factors in Amniotic Fluid and Breast Milk that Contribute to Gut Maturation, Clinical Reviews in Allergy & Immunology, vol.36, issue.2, pp.191-204, 2008.
DOI : 10.1007/s12016-007-8032-3

R. E. Ward, M. Niñonuevo, D. A. Mills, C. B. Lebrilla, and J. B. German, In vitro fermentability of human milk oligosaccharides by several strains of bifidobacteria, Molecular Nutrition & Food Research, vol.77, issue.11, pp.511398-1405, 2007.
DOI : 10.1002/mnfr.200700150

J. A. Weber, D. H. Baxter, S. Zhang, D. Y. Huang, K. H. Huang et al., The microRNA spectrum in 12 body fluids The intestinal bacterial colonisation in preterm infants: a review of the literature Adiponectin and leptin in maternal serum, cord blood, and breast milk, u t h o r s v e r s i o n, pp.1733-1741361, 2006.

B. Stahl and E. A. Van-tol, Polyunsaturated fatty acids support epithelial barrier integrity and reduce IL-4 mediated permeability in vitro, Eur. J. Nutr, vol.47, issue.4, pp.183-191, 2008.

J. Wolinski, M. Biernat, P. Guilloteau, B. R. Westrom, and R. Zabielski, Exogenous leptin controls the development of the small intestine in neonatal piglets, Journal of Endocrinology, vol.177, issue.2, pp.215-222, 2003.
DOI : 10.1677/joe.0.1770215

L. Xie and S. M. Innis, Genetic Variants of the FADS1 FADS2 Gene Cluster Are Associated with Altered (n-6) and (n-3) Essential Fatty Acids in Plasma and Erythrocyte Phospholipids in Women during Pregnancy and in Breast Milk during Lactation, Journal of Nutrition, vol.138, issue.11, pp.1382222-2228, 2008.
DOI : 10.3945/jn.108.096156

R. J. Xu, D. J. Mellor, M. J. Birtles, B. H. Breier, and P. D. Gluckman, Effects of Oral IGF-I or IGF-II on Digestive Organ Growth in Newborn Piglets, Neonatology, vol.66, issue.5, pp.66280-287, 1994.
DOI : 10.1159/000244118

J. Xu, V. Anderson, and S. M. Schwarz, Dietary GD3 ganglioside reduces the incidence and severity of necrotizing enterocolitis (NEC) by sustaining regulatory immune responses, J. Pediatr. Gastroenterol. Nutr, vol.2013, issue.575, pp.550-556

E. Yavin, A. Brand, and P. Green, Docosahexaenoic Acid Abundance in the Brain: A biodevice to Combat Oxidative Stress, Nutritional Neuroscience, vol.263, issue.3, pp.149-157, 2002.
DOI : 10.1016/0891-5849(94)00155-D

R. H. Yolken, J. A. Peterson, S. L. Vonderfecht, E. T. Fouts, K. Midthun et al., Human milk mucin inhibits rotavirus replication and prevents experimental gastroenteritis., Journal of Clinical Investigation, vol.90, issue.5, pp.901984-1991, 1992.
DOI : 10.1172/JCI116078

Y. Zhang, Y. Cheng, G. H. Hansen, L. L. Niels-christiansen, F. Koentgen et al., Crucial role of alkaline sphingomyelinase in sphingomyelin digestion: a study on enzyme knockout mice, The Journal of Lipid Research, vol.52, issue.4, pp.771-781, 2011.
DOI : 10.1194/jlr.M012880

Y. Zhou, X. Sun, L. Jin, T. Stringfield, L. Lin et al., Expression profiles of adiponectin receptors in mouse embryos, Gene Expression Patterns, vol.5, issue.5, pp.711-715, 2005.
DOI : 10.1016/j.modgep.2005.02.002

Q. Zhou, M. Li, X. Wang, Q. Li, T. Wang et al., Immune-related MicroRNAs are Abundant in Breast Milk Exosomes, International Journal of Biological Sciences, vol.8, issue.1, pp.118-123
DOI : 10.7150/ijbs.8.118