R. Adamson, M. Logan, J. Kinnaird, G. Langsley, and R. Hall, Loss of matrix metalloproteinase 9 activity in Theileria annulata-attenuated cells is at the transcriptional level and is associated with differentially expressed AP-1 species, Molecular and Biochemical Parasitology, vol.106, issue.1, pp.51-61, 2000.
DOI : 10.1016/S0166-6851(99)00213-3

M. Bayliak, D. Gospodaryov, H. Semchyshyn, and V. Lushchak, Inhibition of catalase by aminotriazole in vivo results in reduction of glucose-6-phosphate dehydrogenase activity in Saccharomyces cerevisiae cells, Biochemistry (Moscow), vol.73, issue.4, pp.420-426, 2008.
DOI : 10.1134/S0006297908040068

H. A. Baylis, A. Megson, and R. Hall, Infection with Theileria annulata induces expression of matrix metalloproteinase 9 and transcription factor AP-1 in bovine leucocytes, Molecular and Biochemical Parasitology, vol.69, issue.2, pp.211-222, 1995.
DOI : 10.1016/0166-6851(94)00216-A

S. Bonello, C. Zahringer, R. S. Belaiba, T. Djordjevic, J. Hess et al., Reactive Oxygen Species Activate the HIF-1?? Promoter Via a Functional NF??B Site, Arteriosclerosis, Thrombosis, and Vascular Biology, vol.27, issue.4, pp.755-761, 2007.
DOI : 10.1161/01.ATV.0000258979.92828.bc

C. Botteron and D. Dobbeldeare, AP-1 and ATF-2 Are Constitutively Activated via the JNK Pathway inTheileria parva-Transformed T-Cells, Biochemical and Biophysical Research Communications, vol.246, issue.2, pp.418-421, 1998.
DOI : 10.1006/bbrc.1998.8635

M. Chaussepied and G. Langsley, Theileria transformation of bovine leukocytes: A parasite model for the study of lymphoproliferation, Research in Immunology, vol.147, issue.3, pp.127-138, 1996.
DOI : 10.1016/0923-2494(96)83165-8

M. Chaussepied, D. Lallemand, M. F. Moreau, R. Adamson, R. Hall et al., Upregulation of Jun and Fos family members and permanent JNK activity lead to constitutive AP-1 activation in Theileria-transformed leukocytes, Molecular and Biochemical Parasitology, vol.94, issue.2, pp.215-226, 1998.
DOI : 10.1016/S0166-6851(98)00070-X

M. Chaussepied, N. Janski, M. Baumgartner, R. Lizundia, K. Jensen et al., TGF-b2 Induction Regulates Invasiveness of Theileria-Transformed Leukocytes and Disease Susceptibility, PLoS Pathogens, vol.573, issue.11, p.1001197, 2010.
DOI : 10.1371/journal.ppat.1001197.s008

M. A. Darghouth, Review on the experience with live attenuated vaccines against tropical theileriosis in Tunisia: Considerations for the present and implications for the future, Vaccine, vol.26, pp.4-10, 2008.
DOI : 10.1016/j.vaccine.2008.09.065

M. A. Darghouth, B. Miled, L. Bouattour, A. Melrose, T. R. Brown et al., A preliminary study on the attenuation of Tunisian schizont-infected cell lines of Theileria annulata, Parasitology Research, vol.82, issue.7, pp.647-655, 1996.
DOI : 10.1007/s004360050179

H. Y. Fang, R. Hughes, C. Murdoch, S. B. Coffelt, S. K. Biswas et al., Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia, Blood, vol.114, issue.4, pp.844-859, 2009.
DOI : 10.1182/blood-2008-12-195941

S. Frede, U. Berchner-pfannschmidt, and J. Fandrey, Regulation of Hypoxia???Inducible Factors During Inflammation, Methods Enzymol, vol.435, pp.405-419, 2007.
DOI : 10.1016/S0076-6879(07)35021-0

Y. Galley, G. Hagens, I. Glaser, W. Davis, M. Eichhorn et al., Jun NH2-terminal kinase is constitutively activated in T cells transformed by the intracellular parasite Theileria parva, Proceedings of the National Academy of Sciences, vol.94, issue.10, pp.5119-5124, 1997.
DOI : 10.1073/pnas.94.10.5119

H. Ginsburg, Progress in in silico functional genomics: the malaria Metabolic Pathways database, Trends in Parasitology, vol.22, issue.6, pp.238-240, 2006.
DOI : 10.1016/j.pt.2006.04.008

R. Hall, T. Ilhan, E. Kirvar, G. Wilkie, P. M. Preston et al., Mechanism(s) of attenuation of Theileria annulata vaccine cell lines, Tropical Medicine and International Health, vol.7, issue.9, pp.78-84, 1999.
DOI : 10.1006/expr.1996.0056

K. Jensen, R. Talbot, E. Paxton, D. Waddington, and E. J. Glass, Development and validation of a bovine macrophage specific cDNA microarray, BMC Genomics, vol.7, issue.1, p.224, 2006.
DOI : 10.1186/1471-2164-7-224

K. Jensen, E. Paxton, D. Waddington, R. Talbot, M. A. Darghouth et al., Differences in the transcriptional responses induced by Theileria annulata infection in bovine monocytes derived from resistant and susceptible cattle breeds, International Journal for Parasitology, vol.38, issue.3-4, pp.313-325, 2008.
DOI : 10.1016/j.ijpara.2007.08.007

A. M. Jubb, F. M. Buffa, and A. L. Harris, Assessment of tumour hypoxia for prediction of response to therapy and cancer prognosis, Journal of Cellular and Molecular Medicine, vol.14, issue.1-2, pp.18-29, 2010.
DOI : 10.1111/j.1582-4934.2009.00944.x

B. Keith, R. S. Johnson, and M. C. Simon, HIF1alpha and HIF2alpha: sibling rivalry in hypoxic tumour growth and progression, Nat Rev Cancer, vol.12, pp.9-22, 2012.

M. Y. Koh and G. Powis, Passing the baton: the HIF switch, Trends in Biochemical Sciences, vol.37, issue.9, pp.364-372, 2012.
DOI : 10.1016/j.tibs.2012.06.004

A. J. Levine and A. M. Puzio-kuter, The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes, Science, vol.330, issue.6009, pp.1340-1344, 2010.
DOI : 10.1126/science.1193494

R. Lizundia, M. Chaussepied, M. Huerre, D. Werling, D. Santo et al., c-Jun NH2-Terminal Kinase/c-Jun Signaling Promotes Survival and Metastasis of B Lymphocytes Transformed by Theileria, Cancer Research, vol.66, issue.12, pp.6105-6110, 2006.
DOI : 10.1158/0008-5472.CAN-05-3861

D. J. Manalo, A. Rowan, T. Lavoie, L. Natarajan, B. D. Kelly et al., Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1, Blood, vol.105, issue.2, pp.659-669, 2005.
DOI : 10.1182/blood-2004-07-2958

S. Medjkane, M. Perichon, J. Marsolier, J. Dairou, and J. B. Weitzman, Theileria induces oxidative stress and HIF1? activation that are essential for host leukocyte transformation. Oncogene; Advance online publication 13, 2013.

G. H. Palmer, J. Machado, . Jr, P. Fernandez, V. Heussler et al., Parasite-mediated nuclear factor ??B regulation in lymphoproliferation caused by Theileria parva infection, Proceedings of the National Academy of Sciences, vol.94, issue.23, pp.12527-12532, 1997.
DOI : 10.1073/pnas.94.23.12527

M. W. Pfaffl, A new mathematical model for relative quantification in real-time RT-PCR, Nucleic Acids Research, vol.29, issue.9, p.45, 2001.
DOI : 10.1093/nar/29.9.e45

V. Pialoux, R. Mounier, A. D. Brown, C. D. Steinback, J. M. Rawling et al., Relationship between oxidative stress and HIF-1?? mRNA during sustained hypoxia in humans, Free Radical Biology and Medicine, vol.46, issue.2, pp.321-326, 2009.
DOI : 10.1016/j.freeradbiomed.2008.10.047

H. M. Shen and Z. G. Liu, JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species, Free Radical Biology and Medicine, vol.40, issue.6, pp.928-939, 2006.
DOI : 10.1016/j.freeradbiomed.2005.10.056

D. K. Singh, Methods currently used for the control of Theileria annulata: their validity and proposals for future control strategies, Parassitologia, vol.32, pp.33-40, 1990.

W. Spear, D. Chan, I. Coppens, R. S. Johnson, A. Giaccia et al., The host cell transcription factor hypoxia-inducible factor 1 is required for Toxoplasma gondii growth and survival at physiological oxygen levels, Cellular Microbiology, vol.95, issue.2, pp.339-352, 2006.
DOI : 10.1128/IAI.69.1.501-507.2001

G. H. Theilen, J. D. Rush, W. A. Nelson-rees, D. L. Dungworth, R. J. Munn et al., Bovine leukemia: establishment and morphologic characterization of continuous cell suspension culture, BL-1, J Natl Cancer Inst, vol.40, pp.737-749, 1968.

P. A. Walton and M. Pizzitelli, Effects of peroxisomal catalase inhibition on mitochondrial function, Frontiers in Physiology, vol.3, p.108, 2012.
DOI : 10.3389/fphys.2012.00108

G. L. Wang, B. H. Jiang, E. A. Rue, and G. L. Semenza, Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension., Proceedings of the National Academy of Sciences, vol.92, issue.12, pp.5510-5514, 1995.
DOI : 10.1073/pnas.92.12.5510

O. Warburg, On respiratory impairment in cancer cells, Science, vol.124, pp.269-270, 1956.

M. Wiley, K. R. Sweeney, D. A. Chan, K. M. Brown, C. Mcmurtrey et al., Toxoplasma gondii Activates Hypoxia-inducible Factor (HIF) by Stabilizing the HIF-1?? Subunit via Type I Activin-like Receptor Kinase Receptor Signaling, Journal of Biological Chemistry, vol.285, issue.35, pp.26852-26860, 2010.
DOI : 10.1074/jbc.M110.147041

A. Wolf, S. Agnihotri, J. Micallef, J. Mukherjee, N. Sabha et al., Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme, The Journal of Experimental Medicine, vol.124, issue.2, pp.313-326, 2011.
DOI : 10.1126/science.1170944