Dormancy of metastatic melanoma, Pigment Cell & Melanoma Research, vol.157, issue.Suppl 2, pp.41-56, 2010. ,
DOI : 10.1111/j.1755-148X.2009.00647.x
Transmission of donor melanoma by organ transplantation, The Lancet Oncology, vol.11, issue.8, pp.790-796, 2010. ,
DOI : 10.1016/S1470-2045(10)70024-3
Models, mechanisms and clinical evidence for cancer dormancy, Nature Reviews Cancer, vol.20, issue.11, pp.834-846, 2007. ,
DOI : 10.1038/nrc2256
Chronic myeloid leukemia stem cells in the era of targeted therapies: resistance, persistence and long-term dormancy, Oncotarget, vol.2, issue.9, pp.713-727, 2011. ,
DOI : 10.18632/oncotarget.333
Cancer stem cells: In the line of fire, Cancer Treatment Reviews, vol.38, issue.6, pp.589-598, 2012. ,
DOI : 10.1016/j.ctrv.2012.03.003
Cancer drug pan-resistance: pumps, cancer stem cells, quiescence, epithelial to mesenchymal transition, blocked cell death pathways, persisters or what?, Open Biology, vol.483, issue.7391, pp.120066-120066, 2012. ,
DOI : 10.1038/483546a
Colon Cancer Cells Escape 5FU Chemotherapy-Induced Cell Death by Entering Stemness and Quiescence Associated with the c-Yes/YAP Axis, Clinical Cancer Research, vol.20, issue.4, pp.837-846, 2014. ,
DOI : 10.1158/1078-0432.CCR-13-1854
Targeting leukemic stem cells by breaking their dormancy, Molecular Oncology, vol.8, issue.5, pp.443-450, 2010. ,
DOI : 10.1016/j.molonc.2010.06.001
Development and Maintenance of Cancer Stem Cells under Chronic Inflammation, Journal of Nippon Medical School, vol.78, issue.3, pp.138-145, 2011. ,
DOI : 10.1272/jnms.78.138
Emerging avenues linking inflammation and cancer, Free Radical Biology and Medicine, vol.52, issue.9, pp.2013-2037, 2012. ,
DOI : 10.1016/j.freeradbiomed.2012.02.035
An endotoxin-induced serum factor that causes necrosis of tumors., Proceedings of the National Academy of Sciences, vol.72, issue.9, pp.3666-3670, 1975. ,
DOI : 10.1073/pnas.72.9.3666
Cancer-related inflammation, Nature, vol.342, issue.7203, pp.436-444, 2008. ,
DOI : 10.1038/nature07205
Mechanisms of UV-Induced Inflammation, Journal of Investigative Dermatology, vol.100, issue.1, pp.35-41, 1993. ,
DOI : 10.1038/jid.1993.21
Biological and Molecular Heterogeneity of Breast Cancers Correlates with Their Cancer Stem Cell Content, Cell, vol.140, issue.1, pp.62-73, 2010. ,
DOI : 10.1016/j.cell.2009.12.007
Defining the Epithelial Stem Cell Niche in Skin, Science, vol.303, issue.5656, pp.359-363, 2004. ,
DOI : 10.1126/science.1092436
Histone???GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells, Current Biology, vol.8, issue.7, pp.377-385, 1998. ,
DOI : 10.1016/S0960-9822(98)70156-3
Breaking the Cell Cycle of HSCs by p57 and Friends, Cell Stem Cell, vol.9, issue.3, pp.187-192, 2011. ,
DOI : 10.1016/j.stem.2011.08.005
Identification and targeting of cancer stem cells, BioEssays, vol.11, issue.10, pp.1038-1049, 2009. ,
DOI : 10.1002/bies.200900058
Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271, Nature, vol.453, issue.7302, pp.133-137, 2010. ,
DOI : 10.1038/nature09161
VEGFR-1 Expressed by Malignant Melanoma-Initiating Cells Is Required for Tumor Growth, Cancer Research, vol.71, issue.4, pp.1474-1485, 2011. ,
DOI : 10.1158/0008-5472.CAN-10-1660
Isolation and differentiation properties of neural crest stem cells, Cytometry Part A, vol.2, issue.1, pp.38-47, 2013. ,
DOI : 10.1002/cyto.a.22098
Notch Signaling in the Regulation of Stem Cell Self-Renewal and Differentiation, Curr Top Dev Biol, vol.92, pp.367-409, 2010. ,
DOI : 10.1016/S0070-2153(10)92012-7
Clinical targeting of the TNF and TNFR superfamilies, Nature Reviews Drug Discovery, vol.66, issue.2, pp.147-168, 2013. ,
DOI : 10.1038/nrd3930
Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system, Science, vol.255, issue.5052, pp.1707-1710, 1992. ,
DOI : 10.1126/science.1553558
Spheres of Influence in Cancer Stem Cell Biology, Journal of Investigative Dermatology, vol.131, issue.2, pp.546-547, 2010. ,
DOI : 10.1038/jid.2010.305
Multicellular tumor spheroids: An underestimated tool is catching up again, Journal of Biotechnology, vol.148, issue.1, pp.3-15, 2010. ,
DOI : 10.1016/j.jbiotec.2010.01.012
Analysis of the genome to personalize therapy for melanoma, Oncogene, vol.157, issue.41, pp.5545-5555, 2010. ,
DOI : 10.1038/onc.2008.244
Melanoma Chemotherapy Leads to the Selection of ABCB5-Expressing Cells, PLoS ONE, vol.70, issue.12, p.36762, 2012. ,
DOI : 10.1371/journal.pone.0036762.s002
A Tumorigenic Subpopulation with Stem Cell Properties in Melanomas, Cancer Research, vol.65, issue.20, pp.9328-9337, 2005. ,
DOI : 10.1158/0008-5472.CAN-05-1343
Characterization of an in vitro model of human melanoma invasion based on reconstructed human skin, British Journal of Dermatology, vol.91, issue.Suppl., pp.210-222, 2000. ,
DOI : 10.1046/j.1365-2133.2000.03287.x
The Three-Dimensional Human Skin Reconstruct Model: a Tool to Study Normal Skin and Melanoma Progression, Journal of Visualized Experiments, vol.54, issue.54, p.2937, 2011. ,
DOI : 10.3791/2937
Melanomas resist T-cell therapy through inflammation-induced reversible dedifferentiation, Nature, vol.6, issue.7420, pp.412-416, 2012. ,
DOI : 10.1038/nature11538
Dynamic variation in cycling of hematopoietic stem cells in steady state and inflammation, The Journal of Experimental Medicine, vol.156, issue.2, pp.273-284, 2011. ,
DOI : 10.1016/j.stem.2007.10.020
Chapter 2 PI3K/PTEN Signaling in Angiogenesis and Tumorigenesis, In Adv Cancer Res, vol.102, pp.19-65, 2009. ,
DOI : 10.1016/S0065-230X(09)02002-8
Regulation of Stem Cell Systems by PI3K/Akt Signaling, Regul Netw Stem Cells, pp.309-318, 2009. ,
DOI : 10.1007/978-1-60327-227-8_26
Metabolic requirements for the maintenance of self-renewing stem cells, Nature Reviews Molecular Cell Biology, vol.21, issue.4, pp.243-256, 2014. ,
DOI : 10.1038/nrm3772
AKT/FOXO Signaling Enforces Reversible Differentiation Blockade in Myeloid Leukemias, Cell, vol.146, issue.5, pp.697-708, 2011. ,
DOI : 10.1016/j.cell.2011.07.032
Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation, Nature Cell Biology, vol.128, issue.7, pp.838-845, 2011. ,
DOI : 10.1016/j.stem.2008.09.013
The Role of the PI3K-AKT Pathway in Melanoma, The Cancer Journal, vol.18, issue.2, pp.142-147, 2012. ,
DOI : 10.1097/PPO.0b013e31824d448c
Emerging targeted therapies for melanoma treatment (Review), International Journal of Oncology, vol.45, pp.516-524, 2014. ,
DOI : 10.3892/ijo.2014.2481
NF-??B, chemokine gene transcription and tumour growth, Nature Reviews Immunology, vol.70, issue.9, pp.664-674, 2002. ,
DOI : 10.1038/nri887
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668257
Hierarchies of NF-??B target-gene regulation, Nature Immunology, vol.12, issue.8, pp.689-694, 2011. ,
DOI : 10.1093/emboj/cdg370
Inflammation meets cancer, with NF-??B as the matchmaker, Nature Immunology, vol.104, issue.8, pp.715-723, 2011. ,
DOI : 10.1038/nature09673
Inflammatory signals regulate hematopoietic stem cells, Trends in Immunology, vol.32, issue.2, pp.57-65, 2011. ,
DOI : 10.1016/j.it.2010.12.003
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042730
Akt Is a Downstream Target of NF-kappa B, Journal of Biological Chemistry, vol.277, issue.33, pp.29674-29680, 2002. ,
DOI : 10.1074/jbc.M112464200
Crosstalk in NF-??B signaling pathways, Nature Immunology, vol.13, issue.8, pp.695-708, 2011. ,
DOI : 10.1016/j.cell.2007.07.009
B-cell translocation gene 2 mediates crosstalk between PI3K/Akt1 and NF??B pathways which enhances transcription of MnSOD by accelerating I??B?? degradation in normal and cancer cells, Cell Communication and Signaling, vol.11, issue.1, pp.69-83, 2013. ,
DOI : 10.1016/j.bbrc.2013.03.114
Quiescent, Slow-Cycling Stem Cell Populations in Cancer: A Review of the Evidence and Discussion of Significance, Journal of Oncology, vol.9, issue.6, p.11, 2011. ,
DOI : 10.1038/sj.onc.1202840
Molecular regulation of stem cell quiescence, Nature Reviews Molecular Cell Biology, vol.302, issue.6, pp.329-340, 2013. ,
DOI : 10.1038/nrm3591
Cancer Dormancy: A Model of Early Dissemination and Late Cancer Recurrence, Clinical Cancer Research, vol.18, issue.3, pp.645-653, 2011. ,
DOI : 10.1158/1078-0432.CCR-11-2186
Inflammation and cancer stem cells, Cancer Letters, vol.345, issue.2, pp.271-278, 2014. ,
DOI : 10.1016/j.canlet.2013.07.031
Regulation of Hematopoietic Stem Cell Activity by Inflammation, Frontiers in Immunology, vol.4, pp.204-213, 2013. ,
DOI : 10.3389/fimmu.2013.00204
The Tumor Suppressor p53 Regulates Polarity of Self-Renewing Divisions in Mammary Stem Cells, Cell, vol.138, issue.6, pp.1083-1095, 2009. ,
DOI : 10.1016/j.cell.2009.06.048
The protein kinase B/Akt signalling pathway in human malignancy, Cellular Signalling, vol.14, issue.5, pp.381-395, 2002. ,
DOI : 10.1016/S0898-6568(01)00271-6
PI3K/AKT signaling pathway and cancer: an updated review, Annals of Medicine, vol.15, issue.3, pp.372-383, 2014. ,
DOI : 10.1158/1535-7163.MCT-11-1021
ABCB5 Maintains Melanoma-Initiating Cells through a Proinflammatory Cytokine Signaling Circuit, Cancer Research, vol.74, issue.15, pp.4196-4207, 2014. ,
DOI : 10.1158/0008-5472.CAN-14-0582
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells, Cell, vol.133, issue.4, pp.704-715, 2008. ,
DOI : 10.1016/j.cell.2008.03.027
Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state, Proceedings of the National Academy of Sciences, vol.108, issue.19, pp.7950-7955, 2011. ,
DOI : 10.1073/pnas.1102454108
Transitory FGF Treatment Results in the Long-Lasting Suppression of the Proliferative Response to Repeated FGF Stimulation, Journal of Cellular Biochemistry, vol.268, issue.5, pp.874-888, 2014. ,
DOI : 10.1002/jcb.24731
Understanding cancer stem cell heterogeneity and plasticity, Cell Research, vol.5, issue.3, pp.457-472, 2012. ,
DOI : 10.1038/nm.2415
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292302
SLUG/SNAI2 and Tumor Necrosis Factor Generate Breast Cells With CD44+/CD24- Phenotype, BMC Cancer, vol.297, issue.6, pp.411-427, 2010. ,
DOI : 10.1152/ajpgi.00292.2009
Cell competition: how to eliminate your neighbours, Development, vol.141, issue.5, pp.988-1000, 2014. ,
DOI : 10.1242/dev.079129
Mechanisms of cell competition: Themes and variations, The Journal of Cell Biology, vol.200, issue.6, pp.689-698, 2013. ,
DOI : 10.1242/dev.032383
Selection and adaptation during metastatic cancer progression, Nature, vol.2013, issue.501, pp.365-372 ,
IL-17 and TNF Synergistically Modulate Cytokine Expression while Suppressing Melanogenesis: Potential Relevance to Psoriasis, Journal of Investigative Dermatology, vol.133, issue.12, pp.2741-2752, 2013. ,
DOI : 10.1038/jid.2013.237
Tumor necrosis factor ? triggers proliferation of adult neural stem cells via IKK/NF-?B signaling, BMC Neuroscience, vol.7, issue.1, pp.64-82, 2006. ,
DOI : 10.1186/1471-2202-7-64
TNF?? promotes osteosarcoma progression by maintaining tumor cells in an undifferentiated state, Oncogene, vol.80, issue.33, pp.4236-4241, 2013. ,
DOI : 10.1038/onc.2013.545
Bifunctional effects of tumor necrosis factor alpha (TNF alpha) on the growth of mature and primitive human hematopoietic progenitor cells: involvement of p55 and p75 TNF receptors, Blood, vol.83, pp.3152-3159, 1994. ,
Tumor necrosis factor restricts hematopoietic stem cell activity in mice: involvement of two distinct receptors, The Journal of Experimental Medicine, vol.86, issue.8, pp.1563-1570, 2011. ,
DOI : 10.1073/pnas.93.9.4040
Tumor necrosis factor (TNF)-mediated activation of the p55 TNF receptor negatively regulates maintenance of cycling reconstituting human hematopoietic stem cells, Blood, vol.98, issue.6, pp.1782-1791, 2001. ,
DOI : 10.1182/blood.V98.6.1782
A Temporarily Distinct Subpopulation of Slow-Cycling Melanoma Cells Is Required for Continuous Tumor Growth, Cell, vol.141, issue.4, pp.583-594, 2010. ,
DOI : 10.1016/j.cell.2010.04.020
Asymmetric cancer cell division regulated by AKT, Proceedings of the National Academy of Sciences, vol.108, issue.31, pp.12845-12850, 2011. ,
DOI : 10.1073/pnas.1109632108
Evidence for alpha-melanocyte-stimulating hormone (??-MSH) receptors on human malignant melanoma cells, International Journal of Cancer, vol.73, issue.2, pp.248-255, 1988. ,
DOI : 10.1002/ijc.2910410216
Asymmetric Distribution of Epidermal Growth Factor Receptor Directs the Fate of Normal and Cancer Keratinocytes In Vitro, Stem Cells and Development, vol.19, issue.2, pp.209-220, 2010. ,
DOI : 10.1089/scd.2009.0150
UV-induced apoptosis in skin equivalents: inhibition by phorbol ester and Bcl-2 overexpression, Cell Death Differ, vol.2, pp.183-193, 1995. ,