B. Hawkins and T. Davis, The Blood-Brain Barrier/Neurovascular Unit in Health and Disease, Pharmacological Reviews, vol.57, issue.2, pp.173-185, 2005.
DOI : 10.1124/pr.57.2.4

D. Kleinfeld, P. Blinder, P. Drew, J. Driscoll, and A. Muller, A Guide to Delineate the Logic of Neurovascular Signaling in the Brain, Frontiers in Neuroenergetics, vol.3, p.1, 2011.
DOI : 10.3389/fnene.2011.00001

B. Moeller, Y. Cao, Z. Vujaskovic, C. Li, and Z. Haroon, The relationship between hypoxia and angiogenesis, Seminars in Radiation Oncology, vol.14, issue.3, pp.215-221, 2004.
DOI : 10.1016/j.semradonc.2004.04.005

R. Jensen, Brain tumor hypoxia: tumorigenesis, angiogenesis, imaging, pseudoprogression, and as a therapeutic target, Journal of Neuro-Oncology, vol.62, issue.4, pp.317-335, 2009.
DOI : 10.1007/s11060-009-9827-2

J. Silvestre, D. Smadja, and B. Levy, Postischemic Revascularization: From Cellular and Molecular Mechanisms to Clinical Applications, Physiological Reviews, vol.93, issue.4, pp.1743-1802, 2013.
DOI : 10.1152/physrev.00006.2013

A. Ergul, A. Alhusban, and S. Fagan, Angiogenesis: A Harmonized Target for Recovery After Stroke, Stroke, vol.43, issue.8, pp.2270-2274, 2012.
DOI : 10.1161/STROKEAHA.111.642710

E. Smith, R. Stroemer, N. Gorenkova, M. Nakajima, and W. Crum, Implantation Site and Lesion Topology Determine Efficacy of a Human Neural Stem Cell Line in a Rat Model of Chronic Stroke, STEM CELLS, vol.42, issue.Pt 6, pp.785-796, 2012.
DOI : 10.1002/stem.1024

Q. Jiang, Z. Zhang, G. Ding, L. Zhang, and J. Ewing, Investigation of neural progenitor cell induced angiogenesis after embolic stroke in rat using MRI, NeuroImage, vol.28, issue.3, pp.698-707, 2005.
DOI : 10.1016/j.neuroimage.2005.06.063

H. Lee, K. Kim, I. Park, and S. Kim, Human Neural Stem Cells Over-Expressing VEGF Provide Neuroprotection, Angiogenesis and Functional Recovery in Mouse Stroke Model, PLoS ONE, vol.187, issue.1, p.156, 2007.
DOI : 10.1371/journal.pone.0000156.t001

E. Bible, D. Chau, M. Alexander, J. Price, and K. Shakesheff, The support of neural stem cells transplanted into stroke-induced brain cavities by PLGA particles, Biomaterials, vol.30, issue.16, pp.2985-2994, 2009.
DOI : 10.1016/j.biomaterials.2009.02.012

E. Bible, F. Dell-'acqua, B. Solanky, A. Balducci, and P. Crapo, Non-invasive imaging of transplanted human neural stem cells and ECM scaffold remodeling in the stroke-damaged rat brain by 19F- and diffusion-MRI, Biomaterials, vol.33, issue.10, pp.2858-2871, 2012.
DOI : 10.1016/j.biomaterials.2011.12.033

H. Ko, B. Milthorpe, and C. Mcfarland, Engineering thick tissues - the vascularisation problem, European Cells and Materials, vol.14, pp.1-18, 2007.
DOI : 10.22203/eCM.v014a01

F. Auger, L. Gibot, and D. Lacroix, The Pivotal Role of Vascularization in Tissue Engineering, Annual Review of Biomedical Engineering, vol.15, issue.1, pp.177-200, 2013.
DOI : 10.1146/annurev-bioeng-071812-152428

D. Emerich, E. Silva, O. Ali, D. Mooney, and W. Bell, Injectable VEGF Hydrogels Produce Near Complete Neurological and Anatomical Protection Following Cerebral Ischemia in Rats, Cell Transplantation, vol.19, issue.9, pp.1063-1071, 2010.
DOI : 10.3727/096368910X498278

E. Bible, O. Qutachi, D. Chau, M. Alexander, and K. Shakesheff, Neo-vascularization of the stroke cavity by implantation of human neural stem cells on VEGF-releasing PLGA microparticles, Biomaterials, vol.33, issue.30, pp.7435-7446, 2012.
DOI : 10.1016/j.biomaterials.2012.06.085

Y. Soda, C. Myskiw, A. Rommel, and I. Verma, Mechanisms of neovascularization and resistance to anti-angiogenic therapies in glioblastoma multiforme, Journal of Molecular Medicine, vol.338, issue.4, pp.439-448, 2013.
DOI : 10.1007/s00109-013-1019-z

T. Maki, K. Hayakawa, L. Pham, C. Xing, and E. Lo, Biphasic Mechanisms of Neurovascular Unit Injury and Protection in CNS Diseases, CNS & Neurological Disorders - Drug Targets, vol.12, issue.3, pp.302-315, 2013.
DOI : 10.2174/1871527311312030004

C. Williams, M. Rauch, M. Michaud, R. Robinson, and H. Xu, Short Term Interactions with Long Term Consequences: Modulation of Chimeric Vessels by Neural Progenitors, PLoS ONE, vol.135, issue.12, p.53208, 2012.
DOI : 10.1371/journal.pone.0053208.g006

J. Madri, Modeling the neurovascular niche: implications for recovery from CNS injury, J Physiol Pharmacol, vol.60, issue.4, pp.95-104, 2009.

J. Luo, J. Martinez, X. Yin, A. Sanchez, and D. Tripathy, Hypoxia induces angiogenic factors in brain microvascular endothelial cells, Microvascular Research, vol.83, issue.2, pp.138-145, 2012.
DOI : 10.1016/j.mvr.2011.11.004

K. Hatherell, P. Couraud, I. Romero, B. Weksler, and G. Pilkington, Development of a three-dimensional, all-human in vitro model of the blood???brain barrier using mono-, co-, and tri-cultivation Transwell models, Journal of Neuroscience Methods, vol.199, issue.2, pp.223-229, 2011.
DOI : 10.1016/j.jneumeth.2011.05.012

Q. Xue, Y. Liu, H. Qi, Q. Ma, and L. Xu, A Novel Brain Neurovascular Unit Model with Neurons, Astrocytes and Microvascular Endothelial Cells of Rat, International Journal of Biological Sciences, vol.9, issue.2, pp.174-189, 2013.
DOI : 10.7150/ijbs.5115

M. Gomez-gaviro, C. Scott, A. Sesay, A. Matheu, and S. Booth, Betacellulin promotes cell proliferation in the neural stem cell niche and stimulates neurogenesis, Proceedings of the National Academy of Sciences, vol.109, issue.4, pp.1317-1322, 2012.
DOI : 10.1073/pnas.1016199109

C. Hicks, L. Stevanato, R. Stroemer, E. Tang, and S. Richardson, In Vivo and In Vitro Characterization of the Angiogenic Effect of CTX0E03 Human Neural Stem Cells, Vivo and In Vitro Characterization of the Angiogenic Effect of CTX0E03 Human Neural Stem Cells, pp.1541-1552, 2013.
DOI : 10.3727/096368912X657936

I. Wilhelm, C. Fazakas, and I. Krizbai, In vitro models of the blood-brain barrier, Acta neurobiologiae experimentalis, vol.71, pp.113-128, 2011.

S. Johansson, J. Price, and M. Modo, Effect of Inflammatory Cytokines on Major Histocompatibility Complex Expression and Differentiation of Human Neural Stem/Progenitor Cells, Stem Cells, vol.18, issue.9, pp.2444-2454, 2008.
DOI : 10.1634/stemcells.2008-0116

K. Pollock, P. Stroemer, S. Patel, L. Stevanato, and A. Hope, A conditionally immortal clonal stem cell line from human cortical neuroepithelium for the treatment of ischemic stroke, Experimental Neurology, vol.199, issue.1, pp.143-155, 2006.
DOI : 10.1016/j.expneurol.2005.12.011

B. Weksler, E. Subileau, N. Perriere, P. Charneau, and K. Holloway, Blood-brain barrier-specific properties of a human adult brain endothelial cell line, The FASEB Journal, vol.19, pp.1872-1874, 2005.
DOI : 10.1096/fj.04-3458fje

B. Weksler, I. Romero, and P. Couraud, The hCMEC/D3 cell line as a model of the human blood brain barrier, Fluids and Barriers of the CNS, vol.10, issue.1, p.16, 2013.
DOI : 10.1038/nbt.2247
URL : https://hal.archives-ouvertes.fr/inserm-00812147

A. Albini and D. Noonan, The ???chemoinvasion??? assay, 25 years and still going strong: the use of reconstituted basement membranes to study cell invasion and angiogenesis, Current Opinion in Cell Biology, vol.22, issue.5, pp.677-689, 2010.
DOI : 10.1016/j.ceb.2010.08.017

K. Robinson, F. Candal, N. Scott, and E. Ades, Seeding of Vascular Grafts with an Immortalized Human Dermal Microvascular Endothelial Cell Line, Angiology, vol.46, issue.2, pp.107-113, 1995.
DOI : 10.1177/000331979504600203

A. Mezentsev, R. Merks, O. Riordan, E. Chen, J. Mendelev et al., Endothelial microparticles affect angiogenesis in vitro: role of oxidative stress, AJP: Heart and Circulatory Physiology, vol.289, issue.3, pp.1106-1114, 2005.
DOI : 10.1152/ajpheart.00265.2005

C. Staton, M. Reed, and N. Brown, A critical analysis of current in vitro and in vivo angiogenesis assays, International Journal of Experimental Pathology, vol.213, issue.3, pp.195-221, 2009.
DOI : 10.1111/j.1365-2613.2008.00633.x

C. Ruhrberg and V. Bautch, Neurovascular development and links to disease, Cellular and Molecular Life Sciences, vol.468, issue.7325, pp.1675-1684, 2013.
DOI : 10.1007/s00018-013-1277-5

A. Quaegebeur, C. Lange, and P. Carmeliet, The Neurovascular Link in Health and Disease: Molecular Mechanisms and Therapeutic Implications, Neuron, vol.71, issue.3, pp.406-424, 2011.
DOI : 10.1016/j.neuron.2011.07.013

A. Armulik, G. Genove, M. M. Nisancioglu, M. Wallgard, and E. , Pericytes regulate the blood???brain barrier, Nature, vol.57, issue.7323, pp.557-561, 2010.
DOI : 10.1038/nature09522

R. Daneman, L. Zhou, A. Kebede, and B. Barres, Pericytes are required for blood???brain barrier integrity during embryogenesis, Nature, vol.43, issue.7323, pp.562-566, 2010.
DOI : 10.1038/nature09513

F. Cardoso, D. Brites, and M. Brito, Looking at the blood???brain barrier: Molecular anatomy and possible investigation approaches, Brain Research Reviews, vol.64, issue.2, pp.328-363, 2010.
DOI : 10.1016/j.brainresrev.2010.05.003

R. Cecchelli, V. Berezowski, S. Lundquist, M. Culot, and M. Renftel, Modelling of the blood???brain barrier in drug discovery and development, Nature Reviews Drug Discovery, vol.90, issue.8, pp.650-661, 2007.
DOI : 10.1038/nrd2368
URL : https://hal.archives-ouvertes.fr/hal-00543630

T. Terasaki, S. Ohtsuki, S. Hori, H. Takanaga, and E. Nakashima, New approaches to in vitro models of blood???brain barrier drug transport, Drug Discovery Today, vol.8, issue.20, pp.944-954, 2003.
DOI : 10.1016/S1359-6446(03)02858-7

N. Abbott, D. Dolman, S. Drndarski, and S. Fredriksson, An Improved In Vitro Blood???Brain Barrier Model: Rat Brain Endothelial Cells Co-cultured with Astrocytes, Methods Mol Biol, vol.814, pp.415-430, 2012.
DOI : 10.1007/978-1-61779-452-0_28

L. Griep, F. Wolbers, B. De-wagenaar, P. Ter-braak, and B. Weksler, BBB ON CHIP: microfluidic platform to mechanically and biochemically modulate blood-brain barrier function, Biomedical Microdevices, vol.19, issue.1, pp.145-150, 2013.
DOI : 10.1007/s10544-012-9699-7

S. Nakagawa, M. Deli, H. Kawaguchi, T. Shimizudani, and T. Shimono, A new blood???brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes, Neurochemistry International, vol.54, issue.3-4, pp.253-263, 2009.
DOI : 10.1016/j.neuint.2008.12.002

Q. Li, M. Michaud, S. Canosa, A. Kuo, and J. Madri, GSK-3??: a signaling pathway node modulating neural stem cell and endothelial cell interactions, Angiogenesis, vol.20, issue.2, pp.173-185, 2011.
DOI : 10.1007/s10456-011-9201-9

E. Conway, C. D. Carmeliet, and P. , Molecular mechanisms of blood vessel growth, Cardiovascular Research, vol.49, issue.3, pp.507-521, 2001.
DOI : 10.1016/S0008-6363(00)00281-9

E. Lippmann, C. Weidenfeller, C. Svendsen, and E. Shusta, Blood-brain barrier modeling with co-cultured neural progenitor cell-derived astrocytes and neurons, Journal of Neurochemistry, vol.86, issue.3, pp.507-520, 2011.
DOI : 10.1111/j.1471-4159.2011.07434.x

C. Montenegro, C. Salla-pontes, J. Ribeiro, A. Machado, and R. Ramos, Blocking ??v??3 integrin by a recombinant RGD disintegrin impairs VEGF signaling in endothelial cells, Biochimie, vol.94, issue.8, pp.1812-1820, 2012.
DOI : 10.1016/j.biochi.2012.04.020

D. Grant, H. Kleinman, and G. Martin, The Role of Basement Membranes in Vascular Development, Annals of the New York Academy of Sciences, vol.254, issue.1 Embryonic Ori, pp.61-72, 1990.
DOI : 10.1083/jcb.94.3.511

R. Soares, S. Guo, F. Gartner, F. Schmitt, and J. Russo, 17??-Estradiol-Mediated Vessel Assembly and Stabilization in Tumor Angiogenesis Requires TGF?? and EGFR Crosstalk, Angiogenesis, vol.6, issue.4, pp.271-281, 2003.
DOI : 10.1023/B:AGEN.0000029413.32882.dd

H. Eilken and R. Adams, Dynamics of endothelial cell behavior in sprouting angiogenesis, Current Opinion in Cell Biology, vol.22, issue.5, pp.617-625, 2010.
DOI : 10.1016/j.ceb.2010.08.010

M. Bernaudin, A. Nouvelot, E. Mackenzie, and E. Petit, Selective Neuronal Vulnerability and Specific Glial Reactions in Hippocampal and Neocortical Organotypic Cultures Submitted to Ischemia, Experimental Neurology, vol.150, issue.1, pp.30-39, 1998.
DOI : 10.1006/exnr.1997.6728

S. Liu, D. Agalliu, C. Yu, and M. Fisher, The Role of Pericytes in Blood-Brain Barrier Function and Stroke, Current Pharmaceutical Design, vol.18, issue.25, pp.3653-3662, 2012.
DOI : 10.2174/138161212802002706

Y. Takeshita and R. Ransohoff, Inflammatory cell trafficking across the blood-brain barrier: chemokine regulation and in vitro models, Immunological Reviews, vol.178, issue.1, pp.228-239, 2012.
DOI : 10.1111/j.1600-065X.2012.01127.x

T. Arnold and C. Betsholtz, The importance of microglia in the development of the vasculature in the central nervous system, Vascular Cell, vol.5, issue.1, p.4, 2013.
DOI : 10.1186/2045-824X-5-4

B. Baker and C. Chen, Deconstructing the third dimension ??? how 3D culture microenvironments alter cellular cues, Journal of Cell Science, vol.125, issue.13, pp.3015-3024, 2012.
DOI : 10.1242/jcs.079509

G. Eng, B. Lee, H. Parsa, C. Chin, and J. Schneider, Assembly of complex cell microenvironments using geometrically docked hydrogel shapes, Proceedings of the National Academy of Sciences, vol.110, issue.12, pp.4551-4556, 2013.
DOI : 10.1073/pnas.1300569110