H. Aizawa, M. Kobayashi, S. Tanaka, T. Fukai, and H. Okamoto, Molecular characterization of the subnuclei in rat habenula, The Journal of Comparative Neurology, vol.88, issue.18, pp.4051-4066, 2012.
DOI : 10.1002/cne.23167

K. H. Andres, M. Von-during, and R. W. Veh, Subnuclear organization of the rat habenular complexes, 1<130::aid-cne10>3.0.co, pp.130-150, 1999.
DOI : 10.1002/(SICI)1096-9861(19990428)407:1<130::AID-CNE10>3.0.CO;2-8

M. Araki, P. Mcgeer, and E. Mcgeer, Retrograde HRP tracing combined with a pharmacohistochemical method for GABA transaminase for the identification of presumptive GABAergic projections to the habenula, Brain Research, vol.304, issue.2, pp.271-277, 1984.
DOI : 10.1016/0006-8993(84)90330-5

M. Barrot, S. R. Sesack, F. Georges, M. Pistis, S. Hong et al., Braking Dopamine Systems: A New GABA Master Structure for Mesolimbic and Nigrostriatal Functions, Journal of Neuroscience, vol.32, issue.41, pp.14094-14101, 2012.
DOI : 10.1523/JNEUROSCI.3370-12.2012
URL : https://hal.archives-ouvertes.fr/hal-01160043

C. Bellone, C. Luscher, B. Bettler, K. Kaupmann, J. Mosbacher et al., Cocaine triggered AMPA receptor redistribution is reversed in vivo by mGluR-dependent long-term depression, Nature Neuroscience, vol.7, issue.5, pp.636-641, 1682.
DOI : 10.1038/nn1682

N. Burnashev, H. Monyer, P. H. Seeburg, and B. Sakmann, Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit, Neuron, vol.8, issue.1, pp.189-198, 1992.
DOI : 10.1016/0896-6273(92)90120-3

S. Y. Chang, K. , and U. , Ionic Mechanism of Long-Lasting Discharges of Action Potentials Triggered by Membrane Hyperpolarization in the Medial Lateral Habenula, Journal of Neuroscience, vol.24, issue.9, pp.2172-2181, 2004.
DOI : 10.1523/JNEUROSCI.4891-03.2004

G. R. Christoph, R. J. Leonzio, and K. S. Wilcox, Stimulation of the lateral habenula inhibits dopamine-containing neurons in the substantia nigra and ventral tegmental area of the rat, J. Neurosci, vol.6, pp.613-619, 1986.

R. L. Clem and R. L. Huganir, Calcium-Permeable AMPA Receptor Dynamics Mediate Fear Memory Erasure, Science, vol.330, issue.6007, pp.1108-1112, 2010.
DOI : 10.1126/science.1195298

S. D. Donevan and M. A. Rogawski, Intracellular polyamines mediate inward rectification of Ca(2+)-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors., Proceedings of the National Academy of Sciences, vol.92, issue.20, pp.9298-9302, 1995.
DOI : 10.1073/pnas.92.20.9298

M. Farrant and Z. Nusser, Variations on an inhibitory theme: phasic and tonic activation of GABAA receptors, Nature Reviews Neuroscience, vol.18, issue.3, pp.215-229, 2005.
DOI : 10.1006/frne.1999.0188

S. Geisler, K. H. Andres, and R. W. Veh, Morphologic and cytochemical criteria for the identification and delineation of individual subnuclei within the lateral habenular complex of the rat, The Journal of Comparative Neurology, vol.633, issue.1, pp.78-97, 2003.
DOI : 10.1002/cne.10566

S. Geisler and M. Trimble, The Lateral Habenula: No Longer Neglected, CNS Spectrums, vol.20, issue.06, pp.484-489, 2008.
DOI : 10.1002/cne.10566

C. H. Good, H. Wang, Y. H. Chen, C. A. Mejias-aponte, A. F. Hoffman et al., Dopamine D4 Receptor Excitation of Lateral Habenula Neurons via Multiple Cellular Mechanisms, Journal of Neuroscience, vol.33, issue.43, pp.16853-16864, 2013.
DOI : 10.1523/JNEUROSCI.1844-13.2013

C. Gruber, A. Kahl, L. Lebenheim, A. Kowski, A. Dittgen et al., Dopaminergic projections from the VTA substantially contribute to the mesohabenular pathway in the rat, Neuroscience Letters, vol.427, issue.3, pp.165-170, 2007.
DOI : 10.1016/j.neulet.2007.09.016

M. Herkenham and W. J. Nauta, Efferent connections of the habenular nuclei in the rat The habenula: from stress evasion to value-based decisionmaking, J. Comp. Neurol. Nat. Rev. Neurosci, vol.187, issue.11, pp.19-47, 1038.

D. R. Hill, GABAB receptor modulation of adenylate cyclase activity in rat brain slices, Br. J. Pharmacol, vol.84, pp.249-257, 1985.

M. Hollmann, C. Maron, and S. Heinemann, N-glycosylation site tagging suggests a three transmembrane domain topology for the glutamate receptor GluR1, Neuron, vol.13, issue.6, pp.1331-1343, 1994.
DOI : 10.1016/0896-6273(94)90419-7

S. Hong and O. Hikosaka, The Globus Pallidus Sends Reward-Related Signals to the Lateral Habenula, Neuron, vol.60, issue.4, pp.720-729, 2008.
DOI : 10.1016/j.neuron.2008.09.035

H. Hortnagl, R. O. Tasan, A. Wieselthaler, E. Kirchmair, W. Sieghart et al., Patterns of mRNA and protein expression for 12 GABAA receptor subunits in the mouse brain, Neuroscience, vol.236, pp.345-372, 2013.
DOI : 10.1016/j.neuroscience.2013.01.008

T. C. Jhou, H. L. Fields, M. G. Baxter, C. B. Saper, and P. C. Holland, The Rostromedial Tegmental Nucleus (RMTg),??a GABAergic Afferent to Midbrain Dopamine Neurons, Encodes Aversive Stimuli and Inhibits Motor Responses, Neuron, vol.61, issue.5, pp.786-800, 2009.
DOI : 10.1016/j.neuron.2009.02.001

T. C. Jhou, C. H. Good, C. S. Rowley, S. P. Xu, H. Wang et al., Cocaine Drives Aversive Conditioning via Delayed Activation of Dopamine-Responsive Habenular and Midbrain Pathways, Journal of Neuroscience, vol.33, issue.17, pp.7501-75123634, 2013.
DOI : 10.1523/JNEUROSCI.3634-12.2013

L. Kelly, M. Farrant, and S. G. Candy, Synaptic mGluR activation drives plasticity of calcium-permeable AMPA receptors, Nature Neuroscience, vol.87, issue.5, pp.593-601, 2009.
DOI : 10.1016/j.tins.2003.09.007

A. S. Keys and G. D. Ellison, Long-Term Alterations in Benzodiazepine, Muscarinic and ??-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) Receptor Density Following Continuous Cocaine Administration, Pharmacology & Toxicology, vol.552, issue.5, pp.144-150, 1999.
DOI : 10.1111/j.1600-0773.1999.tb00082.x

A. B. Kowski, R. W. Veh, and T. Weiss, Dopaminergic activation excites rat lateral habenular neurons in vivo, Neuroscience, vol.161, issue.4, 2009.
DOI : 10.1016/j.neuroscience.2009.04.026

D. M. Kullmann and K. P. Lamsa, LTP and LTD in cortical GABAergic interneurons: Emerging rules and roles, Neuropharmacology, vol.60, issue.5, 2011.
DOI : 10.1016/j.neuropharm.2010.12.020

S. Lammel, B. K. Lim, C. Ran, K. W. Huang, M. J. Betley et al., Input-specific control of reward and aversion in the ventral tegmental area Anti-Hebbian long-term potentiation in the hippocampal feedback inhibitory circuit, Nature Science, vol.49111, issue.315, pp.212-217, 2007.

L. Roux, N. Cabezas, C. Bohm, U. L. Poncer, and J. C. , Input-specific learning rules at excitatory synapses onto hippocampal parvalbumin-expressing interneurons, The Journal of Physiology, vol.31, issue.suppl 1, pp.1809-1822, 2013.
DOI : 10.1113/jphysiol.2012.245852

B. Li, J. Piriz, M. Mirrione, C. Chung, C. D. Proulx et al., Synaptic potentiation onto habenula neurons in the learned helplessness model of depression, Nature, vol.8, issue.7335, pp.535-539, 1038.
DOI : 10.1038/nature09742

K. Li, T. Zhou, L. Liao, Z. Yang, C. Wong et al., ??CaMKII in Lateral Habenula Mediates Core Symptoms of Depression, Science, vol.341, issue.6149, pp.1016-1020, 2013.
DOI : 10.1126/science.1240729

F. Liang, Y. Hatanaka, H. Saito, T. Yamamori, and T. Hashikawa, Differential expression of gamma-aminobutyric acid type B receptor-1a and -1b mRNA variants in GABA and non-GABAergic neurons of the rat brain, J. Comp. Neurol, vol.416416, pp.475-495, 2000.

Y. Liu, C. D. Fowler, L. J. Young, Q. Yan, T. R. Insel et al., Expression and estrogen regulation of brain-derived neurotrophic factor gene and protein in the forebrain of female prairie voles, The Journal of Comparative Neurology, vol.4, issue.4, pp.499-514, 2001.
DOI : 10.1002/cne.1156

H. Lomeli, J. Mosbacher, T. Melcher, T. Hoger, J. R. Geiger et al., Control of kinetic properties of AMPA receptor channels by nuclear RNA editing, Science, vol.266, issue.5191, pp.1709-1713, 1994.
DOI : 10.1126/science.7992055

R. Lujan, C. , and F. , GABAB Receptors-Associated Proteins: Potential Drug Targets in Neurological Disorders?, Current Drug Targets, vol.13, issue.1, pp.129-144, 2012.
DOI : 10.2174/138945012798868425

C. Luscher and K. M. Huber, Group 1 mGluR-Dependent Synaptic Long-Term Depression: Mechanisms and Implications for Circuitry and Disease, Neuron, vol.65, issue.4, pp.445-459, 2010.
DOI : 10.1016/j.neuron.2010.01.016

C. Luscher, L. Y. Jan, M. Stoffel, R. C. Malenka, and R. A. Nicoll, G Protein-Coupled Inwardly Rectifying K+ Channels (GIRKs) Mediate Postsynaptic but Not Presynaptic Transmitter Actions in Hippocampal Neurons, Neuron, vol.19, issue.3, pp.687-695, 1997.
DOI : 10.1016/S0896-6273(00)80381-5

C. Luscher and P. A. Slesinger, Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease, Nature Reviews Neuroscience, vol.99, issue.5, pp.301-315, 1038.
DOI : 10.1038/nrn2834

M. Mameli, C. Bellone, M. T. Brown, and C. Luscher, Cocaine inverts rules for synaptic plasticity of glutamate transmission in the ventral tegmental area, Nature Neuroscience, vol.14, issue.4, pp.414-416, 2011.
DOI : 10.1038/nn.2367

M. Mameli, B. Halbout, C. Creton, D. Engblom, J. R. Parkitna et al., Cocaine-evoked synaptic plasticity: persistence in the VTA triggers adaptations in the NAc, Nature Neuroscience, vol.20, issue.8, pp.1036-1041, 2009.
DOI : 10.1111/j.1460-9568.2004.03206.x

M. Margeta-mitrovic, I. Mitrovic, R. C. Riley, L. Y. Jan, and A. I. Basbaum, Immunohistochemical localization of GABA(B) receptors in the rat central nervous system, 3<299::AID-CNE2>3.0.CO, pp.299-321, 1999.

M. Maroteaux and M. Mameli, Cocaine Evokes Projection-Specific Synaptic Plasticity of Lateral Habenula Neurons, Journal of Neuroscience, vol.32, issue.36, pp.12641-12646, 2012.
DOI : 10.1523/JNEUROSCI.2405-12.2012

F. H. Marshall, K. A. Jones, K. Kaupmann, and B. Bettler, GABAB receptors ??? the first 7TM heterodimers, Trends in Pharmacological Sciences, vol.20, issue.10, pp.396-399, 1999.
DOI : 10.1016/S0165-6147(99)01383-8

M. Matsumoto and O. Hikosaka, Lateral habenula as a source of negative reward signals in dopamine neurons, Nature, vol.439, issue.7148, pp.1111-1115, 2007.
DOI : 10.1038/nature05860

M. Matsumoto and O. Hikosaka, Two types of dopamine neuron distinctly convey positive and negative motivational signals, Nature, vol.96, issue.7248, pp.837-841, 2009.
DOI : 10.1038/nature08028

J. E. Mccutcheon, J. A. Loweth, K. A. Ford, M. Marinelli, M. E. Wolf et al., Group I mGluR Activation Reverses Cocaine-Induced Accumulation of Calcium-Permeable AMPA Receptors in Nucleus Accumbens Synapses via a Protein Kinase C-Dependent Mechanism, Journal of Neuroscience, vol.31, issue.41, pp.14536-145413625, 2011.
DOI : 10.1523/JNEUROSCI.3625-11.2011

G. Mengod, M. Pompeiano, M. I. Martinez-mir, and J. M. Palacios, Localization of the mRNA for the 5-HT2 receptor by in situ hybridization histochemistry. Correlation with the distribution of receptor sites, Brain Research, vol.524, issue.1, pp.139-143, 1990.
DOI : 10.1016/0006-8993(90)90502-3

C. K. Meshul, K. Noguchi, N. Emre, and G. Ellison, Cocaineinduced changes in glutamate and GABA immunolabeling within rat habenula and nucleus accumbens, Synapse, vol.3030, issue.2<211, pp.1098-2396, 1998.

C. Peyron, D. K. Tighe, A. N. Van-den-pol, L. De-lecea, H. C. Heller et al., Neurons containing hypocretin (orexin) project to multiple neuronal systems, J. Neurosci, vol.18, pp.9996-10015, 1998.

O. T. Phillipson and C. J. Pycock, Dopamine neurones of the ventral tegmentum project to both medial and lateral habenula. Some implications for habenular function, Exp. Brain Res, vol.45, pp.89-94, 1982.

S. Pirker, GABAA receptors: immunocytochemical distribution of 13 subunits in the adult rat brain, Neuroscience, vol.101, issue.4, pp.815-850, 2000.
DOI : 10.1016/S0306-4522(00)00442-5

W. C. Poller, Lateral habenular neurons projecting to rewardprocessing monoaminergic nuclei express hyperpolarization-activated cyclic nucleotid-gated cation channels, Neuroscience, vol.193, 2011.

B. D. Rood, E. K. Murray, J. Laroche, M. K. Yang, J. D. Blaustein et al., Absence of progestin receptors alters distribution of vasopressin fibers but not sexual differentiation of vasopressin system in mice, Neuroscience, vol.154, issue.3, pp.911-921, 2008.
DOI : 10.1016/j.neuroscience.2008.03.087

S. J. Shabel, C. D. Proulx, A. Trias, R. T. Murphy, and R. Malinow, Input to the Lateral Habenula from the Basal Ganglia Is Excitatory, Aversive, and Suppressed by Serotonin, Neuron, vol.74, issue.3, pp.475-481, 2012.
DOI : 10.1016/j.neuron.2012.02.037

X. Shen, X. Ruan, and H. Zhao, Stimulation of midbrain dopaminergic structures modifies firing rates of rat lateral habenula neurons, PLoS One, vol.7, 2012.

Y. Smith, P. Seguela, and A. Parent, Distribution of gaba-immunoreactive neurons in the thalamus of the squirrel monkey (Saimiri sciureus), Neuroscience, vol.22, issue.2, pp.579-591, 1987.
DOI : 10.1016/0306-4522(87)90355-1

R. L. Solomon, C. , and J. D. , An opponent-process theory of motivation: I. Temporal dynamics of affect., Psychological Review, vol.81, issue.2, pp.119-145, 1974.
DOI : 10.1037/h0036128

A. M. Stamatakis and G. D. Stuber, Activation of lateral habenula inputs to the ventral midbrain promotes behavioral avoidance, Nature Neuroscience, vol.15, issue.8, pp.1105-11073145, 2012.
DOI : 10.1038/nprot.2006.279

R. Y. Wang and G. K. Aghajanian, Physiological evidence for habenula as major link between forebrain and midbrain raphe, Science, vol.197, issue.4298, pp.89-91, 1977.
DOI : 10.1126/science.194312

D. G. Wang, N. Gong, B. Luo, and T. L. Xu, Absence of GABA type A signaling in adult medial habenular neurons, Neuroscience, vol.141, issue.1, 2006.
DOI : 10.1016/j.neuroscience.2006.03.045

T. Weiss and R. W. Veh, Morphological and electrophysiological characteristics of neurons within identified subnuclei of the lateral habenula in rat brain slices, Neuroscience, vol.172, 2011.
DOI : 10.1016/j.neuroscience.2010.10.047

L. M. Yang, L. Yu, H. Z. Jin, and H. Zhao, Substance P receptor antagonist in lateral habenula improves rat depression-like behavior, Brain Research Bulletin, vol.100, 2013.
DOI : 10.1016/j.brainresbull.2013.10.007

H. S. Yin, T. W. Tien, L. Li, Y. H. Yang, L. et al., Amphetamine differentially modifies the expression of monoaminergic and GABAergic synaptic boutons and processes in lateral habenula, dorsal and ventral hippocampal formation, NeuroToxicology, vol.33, issue.2, pp.235-245, 2012.
DOI : 10.1016/j.neuro.2011.10.001