H. Li, Y. Li, D. Liu, H. Sun, and J. Liu, miR-224 is Critical for Celastrol-Induced Inhibition of Migration and Invasion of Hepatocellular Carcinoma Cells, Cellular Physiology and Biochemistry, vol.32, issue.2, pp.448-458
DOI : 10.1159/000354450

R. Chakravarthy, M. Clemens, G. Pirianov, N. Perdios, S. Mudan et al., Role of the eIF4E binding protein 4E-BP1 in regulation of the sensitivity of human pancreatic cancer cells to TRAIL and celastrol-induced apoptosis, Biology of the Cell, vol.297, issue.9, pp.414-429, 2013.
DOI : 10.1111/boc.201300021

H. Jiang, J. Jin, D. Wu, D. Xu, G. Lin et al., Celastrol exerts synergistic effects with PHA-665752 and inhibits tumor growth of c-Metdeficient hepatocellular carcinoma in vivo, MolBiolRep2013, issue.7, pp.404203-4209

P. Ge, J. X. Ding, Y. Wang, X. Fu, S. Meng et al., Celastrol causes apoptosis and cell cycle arrest in rat glioma cells, Neurological Research, vol.33, issue.1, pp.94-100, 2010.
DOI : 10.1158/0008-5472.CAN-05-2321

P. Rajendran, F. Li, M. Shanmugam, R. Kannaiyan, J. Goh et al., Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signalingcascadeinvitroandinvivo, Cancer Prev Res (Phila), vol.2012, issue.54, pp.631-643

S. Westerheide, J. Bosman, B. Mbadugha, T. Kawahara, G. Matsumoto et al., Celastrols as Inducers of the Heat Shock Response and Cytoprotection, Journal of Biological Chemistry, vol.279, issue.53, pp.27956053-56060
DOI : 10.1074/jbc.M409267200

M. Kiaei, K. Kipiani, S. Petri, J. Chen, N. Calingasan et al., Celastrol Blocks Neuronal Cell Death and Extends Life in Transgenic Mouse Model of Amyotrophic Lateral Sclerosis, Neurodegenerative Diseases, vol.2, issue.5, pp.246-254, 2005.
DOI : 10.1159/000090364

K. Faust, S. Gehrke, Y. Yang, L. Yang, M. Beal et al., Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease, BMC Neuroscience, vol.10, issue.1, p.109, 2009.
DOI : 10.1186/1471-2202-10-109

D. Jantas, A. Roman, J. Kusmierczyk, E. Lorenc-koci, J. Konieczny et al., The Extent of Neurodegeneration and Neuroprotection in Two Chemical In Vitro Models Related to Parkinson???s Disease is Critically Dependent on Cell Culture Conditions, Neurotoxicity Research, vol.22, issue.Suppl 17, pp.41-54, 2013.
DOI : 10.1007/s12640-012-9374-z

M. Matokanovic, K. Barisic, J. Filipovic-grcic, and D. Maysinger, Hsp70 silencing with siRNA in nanocarriers enhances cancer cell death induced by the inhibitor of Hsp90, European Journal of Pharmaceutical Sciences, vol.50, issue.1, pp.149-158
DOI : 10.1016/j.ejps.2013.04.001

R. Matts, G. Brandt, Y. Lu, A. Dixit, M. Mollapour et al., A systematic protocol for the characterization of Hsp90 modulators, Bioorganic & Medicinal Chemistry, vol.19, issue.1, pp.684-692, 2011.
DOI : 10.1016/j.bmc.2010.10.029

D. Zhang, A. Marconi, L. Xu, C. Yang, G. Sun et al., Tripterine inhibits the expression of adhesion molecules in activated endothelial cells, Journal of Leukocyte Biology, vol.80, issue.2, pp.309-319, 2006.
DOI : 10.1189/jlb.1005611
URL : https://hal.archives-ouvertes.fr/inserm-00180304

L. Klaic, R. Morimoto, and R. Silverman, Celastrol analogues as inducers of the heat shock response. Design and synthesis of affinity probes for the identification of protein targets, ACS Chem Biol, vol.2012, issue.75, pp.928-937

G. Harrison, A. Bennett, M. Moody, G. Read, and P. Williams, Use of formalinfixed , propidium iodide-stained human leukocytes as a standard for enumerating CD4+ T lymphocytes in a single-platform assay, Clin Diagn Lab Immunol, vol.8, issue.2, pp.397-401, 2001.

F. Cao, L. Xu, B. Peng, Q. Xie, G. Uzan et al., A routinely applicable way for using FCM in cell enumeration with CFSE-labeled Cell Beads as internal standard, Cytometry A, issue.12, pp.75975-978, 2009.

C. Doubrovinm, . Serganovai, E. Moroz, D. Solit, L. Ageyeva et al., Monitoring the induction of heat shock factor 1/heat shock protein 70 expression following 17-allylamino- demethoxygeldanamycin treatment by positron emission tomography and optical reporter gene imaging, Mol Imaging, vol.2012, issue.111, pp.67-76

. Conder, . Belakzr, and . Nairm, Modulation of Hsf1 activity by novobiocin and geldanamycin, Biochemistry and Cell Biology, vol.87, issue.6, pp.845-851, 2009.
DOI : 10.1139/O09-049

A. Chow, D. Tang, A. Hanif, and I. Brown, Induction of heat shock proteins in cerebral cortical cultures by celastrol, Cell Stress and Chaperones, vol.86, issue.Suppl 2, pp.155-160
DOI : 10.1007/s12192-012-0364-0

S. Walcott and J. Heikkila, Celastrol can inhibit proteasome activity and upregulate the expression of heat shock protein genes, hsp30 and hsp70, in Xenopus laevis A6 cells, Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, vol.156, issue.2, pp.285-293, 2010.
DOI : 10.1016/j.cbpa.2010.02.015

Y. Zhang and K. Sarge, Celastrol inhibits polyglutamine aggregation and toxicity though induction of the heat shock response, Journal of Molecular Medicine, vol.72, issue.12, pp.1421-1428, 2007.
DOI : 10.1007/s00109-007-0251-9

B. Peng, L. Xu, F. Cao, T. Wei, C. Yang et al., HSP90 inhibitor, celastrol, arrests human monocytic leukemia cell U937 at G0/G1 in thiol-containing agents reversible way, Molecular Cancer, vol.9, issue.1, p.79, 2010.
DOI : 10.1186/1476-4598-9-79
URL : https://hal.archives-ouvertes.fr/inserm-00668221

S. Chen, C. Gu, C. Xu, J. Zhang, Y. Xu et al., Celastrol prevents cadmium-induced neuronal cell death via targeting JNK and PTEN-Akt/mTOR network, Journal of Neurochemistry, vol.334, issue.2, pp.256-266
DOI : 10.1111/jnc.12474

J. Lee, Y. Won, K. Park, M. Lee, H. Tachibana et al., Celastrol inhibits growth and induces apoptotic cell death in melanoma cells via the activation ROS-dependent mitochondrial pathway and the suppression of PI3K/AKT signaling, Apoptosis, vol.557, issue.12, pp.171275-1286
DOI : 10.1007/s10495-012-0767-5

Y. Pangx, . Zhangj, . Lub, . Sungb, and A. Quw, Celastrol Suppresses Angiogenesis-Mediated Tumor Growth through Inhibition of AKT/Mammalian Target of Rapamycin Pathway, Cancer Research, vol.70, issue.5, pp.1951-1959, 2010.
DOI : 10.1158/0008-5472.CAN-09-3201

Y. Li, D. He, X. Zhang, Z. Liu, X. Zhang et al., Protective effect of celastrol in rat cerebral ischemia model: Down-regulating p-JNK, p-c-Jun and NF-??B, Brain Research, vol.1464, pp.8-13, 2012.
DOI : 10.1016/j.brainres.2012.04.054

J. Lee, T. Koo, H. Yoon, H. Jung, H. Jin et al., Inhibition of NF-kappa B activation through targeting I kappa B kinase by celastrol, a quinone methide triterpenoid, Biochem Pharmacol, issue.10, pp.721311-1321, 2006.

H. Zhu, X. Liu, T. Cai, J. Cao, C. Tu et al., Celastrol Acts as a Potent Antimetastatic Agent Targeting ??1 Integrin and Inhibiting Cell-Extracellular Matrix Adhesion, in Part via the p38 Mitogen-Activated Protein Kinase Pathway, Journal of Pharmacology and Experimental Therapeutics, vol.334, issue.2, pp.489-499, 2010.
DOI : 10.1124/jpet.110.165654

A. Sina, S. Lord-dufour, and B. Annabi, Cell-based evidence for aminopeptidase N/CD13 inhibitor actinonin targeting of MT1-MMP-mediated proMMP-2 activation, Cancer Letters, vol.279, issue.2, pp.171-176, 2009.
DOI : 10.1016/j.canlet.2009.01.032

Z. Wang, C. Herzog, G. Kaushal, N. Gokden, and P. Mayeux, Actinonin, a Meprin a Inhibitor, Protects the Renal Microcirculation During Sepsis, Shock, vol.35, issue.2, pp.141-147, 2011.
DOI : 10.1097/SHK.0b013e3181ec39cc

H. Randhawa, S. Chikara, D. Gehring, T. Yildirim, J. Menon et al., Overexpression of peptide deformylase in breast, colon, and lung cancers, BMC Cancer, vol.387, issue.5, p.321, 2013.
DOI : 10.1016/j.jmb.2009.02.032