M. C. Abad, H. Askari, J. O-'neill, A. L. Klinger, C. Milligan et al., Structural determination of estrogen-related receptor ?? in the presence of phenol derivative compounds, The Journal of Steroid Biochemistry and Molecular Biology, vol.108, issue.1-2, pp.44-54, 2008.
DOI : 10.1016/j.jsbmb.2007.06.006

P. Alonso-magdalena, A. B. Ropero, S. Soriano, M. Garcia-arevalo, C. Ripoll et al., Bisphenol-A acts as a potent estrogen via non-classical estrogen triggered pathways, Molecular and Cellular Endocrinology, vol.355, issue.2, pp.201-207, 2012.
DOI : 10.1016/j.mce.2011.12.012

E. A. Ariazi and V. C. Jordan, Estrogen-Related Receptors as Emerging Targets in Cancer and Metabolic Disorders, Current Topics in Medicinal Chemistry, vol.6, issue.3, pp.203-215, 2006.
DOI : 10.2174/1568026610606030203

P. F. Baillie-hamilton, Chemical Toxins: A Hypothesis to Explain the Global Obesity Epidemic, The Journal of Alternative and Complementary Medicine, vol.8, issue.2, pp.185-192, 2002.
DOI : 10.1089/107555302317371479

A. Benecke, P. Chambon, and H. Gronemeyer, Synergy between estrogen receptor ?? activation functions AF1 and AF2 mediated by transcription intermediary factor TIF2, EMBO reports, vol.12, issue.2, pp.151-157, 2000.
DOI : 10.1093/embo-reports/kvd028

J. Bernal, Thyroid hormone receptors in brain development and function, Nature Clinical Practice Endocrinology & Metabolism, vol.82, issue.3, pp.249-259, 2007.
DOI : 10.1038/ncpendmet0424

M. T. Bility, J. T. Thompson, R. H. Mckee, R. M. David, J. H. Butala et al., Activation of Mouse and Human Peroxisome Proliferator-Activated Receptors (PPARs) by Phthalate Monoesters, Toxicological Sciences, vol.82, issue.1, pp.170-182, 2004.
DOI : 10.1093/toxsci/kfh253

M. Bommer, A. Benecke, H. Gronemeyer, and C. Rochette-egly, TIF2 Mediates the Synergy between RARalpha 1 Activation Functions AF-1 and AF-2, Journal of Biological Chemistry, vol.277, issue.40, pp.37961-37966, 2002.
DOI : 10.1074/jbc.M206001200

W. Bourguet, P. Germain, and H. Gronemeyer, Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications, Trends in Pharmacological Sciences, vol.21, issue.10, pp.381-388, 2000.
DOI : 10.1016/S0165-6147(00)01548-0

J. B. Bruning, A. A. Parent, G. Gil, M. Zhao, J. Nowak et al., Coupling of receptor conformation and ligand orientation determine graded activity, Nature Chemical Biology, vol.62, issue.11, pp.837-843, 2010.
DOI : 10.1038/nchembio.451

N. Chevalier, A. Bouskine, and P. Fenichel, Bisphenol A promotes testicular seminoma cell proliferation through GPER/GPR30, International Journal of Cancer, vol.146, issue.1, pp.241-242, 2012.
DOI : 10.1002/ijc.25972

S. Chu, G. D. Haffner, and R. J. Letcher, Simultaneous determination of tetrabromobisphenol A, tetrachlorobisphenol A, bisphenol A and other halogenated analogues in sediment and sludge by high performance liquid chromatography-electrospray tandem mass spectrometry, Journal of Chromatography A, vol.1097, issue.1-2, pp.25-32, 2005.
DOI : 10.1016/j.chroma.2005.08.007

J. F. Couse and K. S. Korach, Estrogen receptor null mice: what have we learned and where will they lead us? Endocrine reviews, pp.358-417, 1999.

P. Coward, D. Lee, M. V. Hull, and J. M. Lehmann, 4-Hydroxytamoxifen binds to and deactivates the estrogen-related receptor ??, Proceedings of the National Academy of Sciences, vol.98, issue.15, pp.8880-8884, 2001.
DOI : 10.1073/pnas.151244398

S. W. Curtis, T. Washburn, C. Sewall, R. Diaugustine, J. Lindzey et al., Physiological coupling of growth factor and steroid receptor signaling pathways: estrogen receptor knockout mice lack estrogen-like response to epidermal growth factor., Proc. Natl. Acad, 1996.
DOI : 10.1073/pnas.93.22.12626

P. O. Darnerud, Toxic effects of brominated flame retardants in man and in wildlife, Environment International, vol.29, issue.6, pp.841-853, 2003.
DOI : 10.1016/S0160-4120(03)00107-7

C. A. De-wit, D. Herzke, and K. Vorkamp, Brominated flame retardants in the Arctic environment ??? trends and new candidates, Science of The Total Environment, vol.408, issue.15, pp.2885-2918
DOI : 10.1016/j.scitotenv.2009.08.037

V. Delfosse, M. Grimaldi, J. Pons, A. Boulahtouf, A. Le-maire et al., Structural and mechanistic insights into bisphenols action provide guidelines for risk assessment and discovery of bisphenol A substitutes, Proc. Natl. Acad, 2012.
DOI : 10.1073/pnas.1203574109
URL : https://hal.archives-ouvertes.fr/inserm-00726779

A. Di-masi, E. D. Marinis, P. Ascenzi, and M. Marino, Nuclear receptors CAR and PXR: Molecular, functional, and biomedical aspects. Molecular aspects of medicine 30, pp.297-343, 2009.

J. Fini, L. Mevel, S. Turque, N. Palmier, K. Zalko et al., An In Vivo Multiwell-Based Fluorescent Screen for Monitoring Vertebrate Thyroid Hormone Disruption, Environmental Science & Technology, vol.41, issue.16, 2007.
DOI : 10.1021/es0704129
URL : https://hal.archives-ouvertes.fr/hal-00179367

J. B. Fini, A. Riu, L. Debrauwer, A. Hillenweck, L. Mevel et al., Parallel Biotransformation of Tetrabromobisphenol A in Xenopus laevis and Mammals: Xenopus as a Model for Endocrine Perturbation Studies, Toxicological Sciences, vol.125, issue.2, pp.359-367, 2012.
DOI : 10.1093/toxsci/kfr312

J. Freitas, P. Cano, C. Craig-veit, M. L. Goodson, J. D. Furlow et al., Detection of thyroid hormone receptor disruptors by a novel stable in vitro reporter gene assay, Toxicology in Vitro, vol.25, issue.1, pp.257-266, 2011.
DOI : 10.1016/j.tiv.2010.08.013

H. Fukazawa, K. Hoshino, T. Shiozawa, H. Matsushita, and Y. Terao, Identification and quantification of chlorinated bisphenol A in wastewater from wastepaper recycling plants, Chemosphere, vol.44, issue.5, 2001.
DOI : 10.1016/S0045-6535(00)00507-5

H. Gallart-ayala, O. Nunez, E. Moyano, and M. T. Galceran, Field-amplified sample injection-micellar electrokinetic capillary chromatography for the analysis of bisphenol A, bisphenol F, and their diglycidyl ethers and derivatives in canned soft drinks, ELECTROPHORESIS, vol.18, issue.9, pp.1550-1559, 2010.
DOI : 10.1002/elps.200900606

A. C. Gee and J. A. Katzenellenbogen, Probing Conformational Changes in the Estrogen Receptor: Evidence for a Partially Unfolded Intermediate Facilitating Ligand Binding and Release, Molecular Endocrinology, vol.15, issue.3, 2001.
DOI : 10.1210/mend.15.3.0602

P. Germain, B. Staels, C. Dacquet, M. Spedding, and V. Laudet, Overview of Nomenclature of Nuclear Receptors, Pharmacological Reviews, vol.58, issue.4, pp.685-704, 2006.
DOI : 10.1124/pr.58.4.2
URL : https://hal.archives-ouvertes.fr/hal-00187929

V. Giguere, To ERR in the estrogen pathway, Trends in Endocrinology & Metabolism, vol.13, issue.5, pp.220-225, 2002.
DOI : 10.1016/S1043-2760(02)00592-1

V. Giguere, Transcriptional Control of Energy Homeostasis by the Estrogen-Related Receptors, Endocrine Reviews, vol.29, issue.6, pp.677-696, 2008.
DOI : 10.1210/er.2008-0017

J. C. Gould, L. S. Leonard, S. C. Maness, B. L. Wagner, K. Conner et al., Bisphenol A interacts with the estrogen receptor ?? in a distinct manner from estradiol, Molecular and Cellular Endocrinology, vol.142, issue.1-2, pp.203-214, 1998.
DOI : 10.1016/S0303-7207(98)00084-7

H. Greschik, J. M. Wurtz, S. Sanglier, W. Bourguet, A. Van-dorsselaer et al., Structural and Functional Evidence for Ligand-Independent Transcriptional Activation by the Estrogen-Related Receptor 3, Molecular Cell, vol.9, issue.2, pp.303-313, 2002.
DOI : 10.1016/S1097-2765(02)00444-6

H. Gronemeyer, J. A. Gustafsson, and V. Laudet, Principles for modulation of the nuclear receptor superfamily, Nature Reviews Drug Discovery, vol.97, issue.11, pp.950-964, 2004.
DOI : 10.1242/jcs.00247

F. Grun, H. Watanabe, Z. Zamanian, L. Maeda, K. Arima et al., Endocrine-Disrupting Organotin Compounds Are Potent Inducers of Adipogenesis in Vertebrates, Molecular Endocrinology, vol.20, issue.9, pp.2141-2155, 2006.
DOI : 10.1210/me.2005-0367

B. He, J. A. Kemppainen, and E. M. Wilson, FXXLF and WXXLF Sequences Mediate the NH2-terminal Interaction with the Ligand Binding Domain of the Androgen Receptor, Journal of Biological Chemistry, vol.275, issue.30, 2000.
DOI : 10.1074/jbc.M002807200

B. Horard and J. M. Vanacker, Estrogen receptor-related receptors: orphan receptors desperately seeking a ligand, Journal of Molecular Endocrinology, vol.31, issue.3, pp.349-357, 2003.
DOI : 10.1677/jme.0.0310349

M. N. Jacobs, G. T. Nolan, and S. R. Hood, Lignans, bacteriocides and organochlorine compounds activate the human pregnane X receptor (PXR), Toxicology and Applied Pharmacology, vol.209, issue.2, pp.123-133, 2005.
DOI : 10.1016/j.taap.2005.03.015

O. Jagnytsch, R. Opitz, I. Lutz, and W. Kloas, Effects of tetrabromobisphenol A on larval development and thyroid hormone, 2006.

J. Kallen, J. M. Schlaeppi, F. Bitsch, I. Filipuzzi, A. Schilb et al., Evidence for ligand-independent transcriptional activation of the human estrogen-related receptor alpha (ERRalpha): crystal structure of ERRalpha ligand binding domain in complex with peroxisome proliferator-activated receptor coactivator-1alpha, J. Biol, 2004.

W. R. Kelce, C. R. Lambright, L. E. Gray, . Jr, and K. P. Roberts, Vinclozolin andp,p???-DDE Alter Androgen-Dependent Gene Expression:In VivoConfirmation of an Androgen Receptor-Mediated Mechanism, Toxicology and Applied Pharmacology, vol.142, issue.1, pp.192-200, 1997.
DOI : 10.1006/taap.1996.7966

S. Kitamura, T. Kato, M. Iida, N. Jinno, T. Suzuki et al., Anti-thyroid hormonal activity of tetrabromobisphenol A, a flame retardant, and related compounds: Affinity to the mammalian thyroid hormone receptor, and effect on tadpole metamorphosis, Life Sciences, vol.76, issue.14, pp.1589-1601, 2005.
DOI : 10.1016/j.lfs.2004.08.030

G. G. Kuiper, B. Carlsson, K. Grandien, E. Enmark, J. Haggblad et al., Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta, Endocrinology, vol.138, pp.863-870, 1997.

B. Leloup, La triiodothyronine, 1977.

G. Lemaire, W. Mnif, J. M. Pascussi, A. Pillon, F. Rabenoelina et al., Identification of new 26, 2006.

J. Li, M. Ma, and Z. Wang, In vitro profiling of endocrine disrupting effects of phenols, Toxicology in Vitro, vol.24, issue.1, 2009.
DOI : 10.1016/j.tiv.2009.09.008

J. Li, M. Ma, and Z. Wang, In vitro profiling of endocrine disrupting effects of phenols, Toxicology in Vitro, vol.24, issue.1, pp.201-207, 2010.
DOI : 10.1016/j.tiv.2009.09.008

H. Liu, H. Zhao, X. Quan, Y. Zhang, and S. Chen, Formation of Chlorinated Intermediate from Bisphenol A in Surface Saline Water under Simulated Solar Light Irradiation, Environmental Science & Technology, vol.43, issue.20, pp.7712-7717, 2009.
DOI : 10.1021/es900811c

D. Lu, Y. Kiriyama, K. Y. Lee, and V. Giguere, Transcriptional regulation of the estrogeninducible pS2 breast cancer marker gene by the ERR family of orphan nuclear receptors, Cancer Res, vol.61, pp.6755-6761, 2001.

T. Matsumoto, M. Sakari, M. Okada, A. Yokoyama, S. Takahashi et al., The Androgen Receptor in Health and Disease, Annual Review of Physiology, vol.75, issue.1, 2012.
DOI : 10.1146/annurev-physiol-030212-183656

A. Matsushima, Y. Kakuta, T. Teramoto, T. Koshiba, X. Liu et al., Structural Evidence for Endocrine Disruptor Bisphenol A Binding to Human Nuclear Receptor ERR??, Journal of Biochemistry, vol.142, issue.4, pp.517-524, 2007.
DOI : 10.1093/jb/mvm158

A. Matsushima, T. Teramoto, H. Okada, X. Liu, T. Tokunaga et al., ERR?? tethers strongly bisphenol A and 4-??-cumylphenol in an induced-fit manner, Biochemical and Biophysical Research Communications, vol.373, issue.3, pp.408-413, 2008.
DOI : 10.1016/j.bbrc.2008.06.050

N. Mccarthy, Prostate cancer: Studying the classics, Nature Reviews Cancer, vol.4, issue.6, 2011.
DOI : 10.1038/nrc3072

J. A. Mclachlan and R. R. Newbold, Estrogens and development, Environmental Health Perspectives, vol.75, pp.25-27, 1987.
DOI : 10.1289/ehp.877525

M. J. Mcphaul, Molecular defects of the androgen receptor, The Journal of Steroid Biochemistry and Molecular Biology, vol.69, issue.1-6, pp.315-322, 1999.
DOI : 10.1016/S0960-0760(99)00050-3

I. A. Meerts, J. J. Van-zanden, E. A. Luijks, I. Van-leeuwen-bol, G. Marsh et al., Potent Competitive Interactions of Some Brominated Flame Retardants and Related Compounds with Human Transthyretin in Vitro, Toxicological Sciences, vol.56, issue.1, pp.95-104, 2000.
DOI : 10.1093/toxsci/56.1.95

E. Mikamo, S. Harada, J. Nishikawa, and T. Nishihara, Endocrine disruptors induce cytochrome P450 by affecting transcriptional regulation via pregnane X receptor, Toxicology and Applied Pharmacology, vol.193, issue.1, pp.66-72, 2003.
DOI : 10.1016/j.taap.2003.08.001

W. Mnif, J. M. Pascussi, A. Pillon, A. Escande, A. Bartegi et al., Estrogens and antiestrogens activate hPXR, Toxicology Letters, vol.170, issue.1, pp.19-29, 2007.
DOI : 10.1016/j.toxlet.2006.11.016

K. Moriyama, T. Tagami, T. Akamizu, T. Usui, M. Saijo et al., Thyroid Hormone Action Is Disrupted by Bisphenol A as an Antagonist, The Journal of Clinical Endocrinology & Metabolism, vol.87, issue.11, pp.5185-5190, 2002.
DOI : 10.1210/jc.2002-020209

Y. Mutou, Y. Ibuki, Y. Terao, S. Kojima, and R. Goto, Change of Estrogenic Activity and Release of Chloride Ion in Chlorinated Bisphenol A after Exposure to Ultraviolet B, Biological & Pharmaceutical Bulletin, vol.29, issue.10, pp.2116-2119, 2006.
DOI : 10.1248/bpb.29.2116

L. Nagy and J. W. Schwabe, Mechanism of the nuclear receptor molecular switch, Trends in Biochemical Sciences, vol.29, issue.6, pp.317-324, 2004.
DOI : 10.1016/j.tibs.2004.04.006

G. L. Greene, NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses, Nat. Chem. Biol, vol.4, pp.241-247, 2008.

R. T. Nolte, G. B. Wisely, S. Westin, J. E. Cobb, M. H. Lambert et al., Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-[gamma], Nature, vol.395, pp.137-143, 1998.

H. Okada, T. Tokunaga, X. Liu, S. Takayanagi, A. Matsushima et al., Direct Evidence Revealing Structural Elements Essential for the High Binding Ability of Bisphenol A to Human Estrogen-Related Receptor-??, Environmental Health Perspectives, vol.116, issue.1, pp.32-38, 2008.
DOI : 10.1289/ehp.10587

J. Orans, D. G. Teotico, and M. R. Redinbo, The Nuclear Xenobiotic Receptor Pregnane X Receptor: Recent Insights and New Challenges, Molecular Endocrinology, vol.19, issue.12, pp.2891-2900, 2005.
DOI : 10.1210/me.2005-0156

F. Paris, P. Balaguer, B. Terouanne, N. Servant, C. Lacoste et al., Phenylphenols, biphenols, bisphenol-A and 4-tert-octylphenol exhibit ?? and ?? estrogen activities and antiandrogen activity in reporter cell lines, Molecular and Cellular Endocrinology, vol.193, issue.1-2, pp.43-49, 2002.
DOI : 10.1016/S0303-7207(02)00094-1

A. C. Pike, Lessons learnt from structural studies of the oestrogen receptor, Best Practice & Research Clinical Endocrinology & Metabolism, vol.20, issue.1, pp.1-14, 2006.
DOI : 10.1016/j.beem.2005.09.002

C. A. Quigley, D. Bellis, A. Marschke, K. B. Awady, M. K. Wilson et al., Androgen Receptor Defects: Historical, Clinical, and Molecular Perspectives*, Endocrine Reviews, vol.16, issue.3, pp.271-321, 1995.
DOI : 10.1210/edrv-16-3-271

J. P. Renaud and D. Moras, Structural studies on nuclear receptors, Cellular and Molecular Life Sciences, vol.57, issue.12, pp.1748-1769, 2000.
DOI : 10.1007/PL00000656

A. Riu, M. Grimaldi, A. Le-maire, G. Bey, K. Phillips et al., Peroxisome Proliferator-Activated Receptor ?? Is a Target for Halogenated Analogs of Bisphenol A, Environmental Health Perspectives, vol.119, issue.9, pp.1227-1232, 2011.
DOI : 10.1289/ehp.1003328

A. Riu, A. Le-maire, M. Grimaldi, M. Audebert, A. Hillenweck et al., Characterization of Novel Ligands of ER??, Er??, and PPAR??: The Case of Halogenated Bisphenol A and Their Conjugated Metabolites, Toxicological Sciences, vol.122, issue.2, pp.372-382, 2011.
DOI : 10.1093/toxsci/kfr132

E. D. Rosen and B. M. Spiegelman, PPAR??: a Nuclear Regulator of Metabolism, Differentiation, and Cell Growth, Journal of Biological Chemistry, vol.276, issue.41, pp.37731-37734, 2001.
DOI : 10.1074/jbc.R100034200

E. J. Routledge, R. White, M. G. Parker, and J. P. Sumpter, Differential effects of xenoestrogens on coactivator recruitment by estrogen receptor (ER) alpha and ERbeta, J. Biol, 2000.

H. Shi, L. Qian, S. Guo, X. Zhang, J. Liu et al., Teratogenic effects of tetrabromobisphenol A on Xenopus tropicalis embryos, Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, vol.152, issue.1, pp.62-68
DOI : 10.1016/j.cbpc.2010.02.013

T. Stroheker, K. Picard, J. C. Lhuguenot, M. C. Canivenc-lavier, and M. C. Chagnon, Steroid activities comparison of natural and food wrap compounds in human breast cancer cell lines, Food and Chemical Toxicology, vol.42, issue.6, 2004.
DOI : 10.1016/j.fct.2004.01.012

Y. Sui, N. Ai, S. H. Park, J. Rios-pilier, J. T. Perkins et al., Bisphenol A and Its Analogues Activate Human Pregnane X Receptor, Environmental Health Perspectives, vol.120, issue.3, pp.399-405, 2012.
DOI : 10.1289/ehp.1104426

H. Sun, O. Shen, X. Wang, L. Zhou, S. Zhen et al., Anti-thyroid hormone activity of bisphenol A, tetrabromobisphenol A and tetrachlorobisphenol A in an improved reporter gene assay, Toxicology in Vitro, vol.23, issue.5, pp.950-954, 2009.
DOI : 10.1016/j.tiv.2009.05.004

M. M. Tabb, V. Kholodovych, F. Grun, C. Zhou, W. J. Welsh et al., Highly Chlorinated PCBs Inhibit the Human Xenobiotic Response Mediated by the Steroid and Xenobiotic Receptor (SXR), Environmental Health Perspectives, vol.112, issue.2, pp.163-169, 2004.
DOI : 10.1289/ehp.6560

M. L. Takacs and B. D. Abbott, Activation of Mouse and Human Peroxisome Proliferator???Activated Receptors (??, ??/??, ??) by Perfluorooctanoic Acid and Perfluorooctane Sulfonate, Toxicological Sciences, vol.95, issue.1, pp.108-117, 2007.
DOI : 10.1093/toxsci/kfl135

H. Takemura, J. Ma, K. Sayama, Y. Terao, B. T. Zhu et al., In vitro and in vivo estrogenic activity of chlorinated derivatives of bisphenol A, Toxicology, vol.207, issue.2, pp.215-221, 2005.
DOI : 10.1016/j.tox.2004.09.015

A. Takeshita, N. Koibuchi, J. Oka, M. Taguchi, Y. Shishiba et al., Bisphenol-A, an environmental estrogen, activates the human orphan nuclear receptor, steroid and xenobiotic receptor-mediated transcription, European Journal of Endocrinology, vol.145, issue.4, pp.513-517, 2001.
DOI : 10.1530/eje.0.1450513

P. Tontonoz, E. Hu, and B. M. Spiegelman, Regulation of adipocyte gene expression and differentiation by peroxisome proliferator activated receptor ??, Current Opinion in Genetics & Development, vol.5, issue.5, pp.571-576, 1995.
DOI : 10.1016/0959-437X(95)80025-5

G. B. Tremblay, T. Kunath, D. Bergeron, L. Lapointe, C. Champigny et al., Diethylstilbestrol regulates trophoblast stem cell differentiation as a ligand of orphan nuclear receptor ERRbeta, Genes & Development, vol.15, issue.7, pp.833-838, 2001.
DOI : 10.1101/gad.873401

J. M. Vanacker, K. Pettersson, J. A. Gustafsson, and V. Laudet, Transcriptional targets shared by estrogen receptor- related receptors (ERRs) and estrogen receptor (ER) alpha , but not by ERbeta, The EMBO Journal, vol.18, issue.15, pp.4270-4279, 1999.
DOI : 10.1093/emboj/18.15.4270

L. N. Vandenberg, M. V. Maffini, C. Sonnenschein, B. S. Rubin, and A. M. Soto, Bisphenol-A and the Great Divide: A Review of Controversies in the Field of Endocrine Disruption, Endocrine Reviews, vol.30, issue.1, pp.75-95, 2009.
DOI : 10.1210/er.2008-0021

N. Veldhoen, A. Boggs, K. Walzak, and C. C. Helbing, Exposure to tetrabromobisphenol-A alters TH-associated gene expression and tadpole metamorphosis in the Pacific tree frog Pseudacris regilla, Aquatic Toxicology, vol.78, issue.3, pp.292-302, 2006.
DOI : 10.1016/j.aquatox.2006.04.002

L. Wang, W. J. Zuercher, T. G. Consler, M. H. Lambert, A. B. Miller et al., X-ray Crystal Structures of the Estrogen-related Receptor-?? Ligand Binding Domain in Three Functional States Reveal the Molecular Basis of Small Molecule Regulation, Journal of Biological Chemistry, vol.281, issue.49, pp.37773-37781, 2006.
DOI : 10.1074/jbc.M608410200

Y. B. Wetherill, B. T. Akingbemi, J. Kanno, J. A. Mclachlan, A. Nadal et al., In vitro molecular mechanisms of bisphenol A action, Reproductive Toxicology, vol.24, issue.2, pp.178-198, 2007.
DOI : 10.1016/j.reprotox.2007.05.010

E. M. Wilson, Analysis of Interdomain Interactions of the Androgen Receptor, Methods in Molecular Biology, vol.776, pp.113-129, 2011.
DOI : 10.1007/978-1-61779-243-4_8

S. Yu, X. Wang, C. F. Ng, S. Chen, and F. L. Chan, ERR?? Suppresses Cell Proliferation and Tumor Growth of Androgen-Sensitive and Androgen-Insensitive Prostate Cancer Cells and Its Implication as a Therapeutic Target for Prostate Cancer, Cancer Research, vol.67, issue.10, pp.4904-4914, 2007.
DOI : 10.1158/0008-5472.CAN-06-3855

P. Figure, Crystal structures of PPAR? LBD in complex with TBBPA and TBBPA-sulfate. (A) Overall structure of the TBBPA-bound PPAR? LBD. The polypeptide backbone is illustrated as a grey ribbon and TBBPA is shown in stick representation

L. Ppar?, black) on the structure with rosiglitazone (grey, PDB code 2PRG) (C) Superimposition of the co-crystal structure of PPAR? LBD bound to TBBPA-sulfate (black) on the structure with TBBPA (grey)

. Roziglitazone, TBBPA and TBBPA-sulfate are shown in stick representation. Figures Tables