Impact of Nanotechnology on Drug Delivery, ACS Nano, vol.3, issue.1, pp.16-20, 2009. ,
DOI : 10.1021/nn900002m
Passive and Active Tumour Targeting with Nanocarriers, Current Drug Discovery Technologies, vol.8, issue.3, pp.188-196, 2011. ,
DOI : 10.2174/157016311796798991
MULTIDRUG RESISTANCE IN CANCER: ROLE OF ATP-DEPENDENT TRANSPORTERS, Nature Reviews Cancer, vol.2, issue.1, pp.48-58, 2002. ,
DOI : 10.1038/nrc706
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response, Nature, vol.8, issue.7120, pp.756-760, 2006. ,
DOI : 10.1038/nature05236
Recent advances with liposomes as pharmaceutical carriers, Nature Reviews Drug Discovery, vol.103, issue.2, pp.145-160, 2005. ,
DOI : 10.1081/LPR-120017488
Biodegradable polymeric nanoparticles based drug delivery systems, Colloids and Surfaces B: Biointerfaces, vol.75, issue.1, pp.1-18, 2010. ,
DOI : 10.1016/j.colsurfb.2009.09.001
A novel phase inversionbased process for the preparation of lipid nanocarriers, Pharmaceutical Research, vol.19, issue.6, pp.875-880, 2002. ,
DOI : 10.1023/A:1016121319668
The influence of lipid nanocapsule composition on their size distribution, Eur J Pharm Sci, vol.18, pp.55-61, 2003. ,
Enhanced Oral Paclitaxel Bioavailability After Administration of Paclitaxel-Loaded Lipid Nanocapsules, Pharmaceutical Research, vol.47, issue.6, pp.1243-1250, 2006. ,
DOI : 10.1007/s11095-006-0022-2
In vivo evaluation of lipid nanocapsules as a promising colloidal carrier for paclitaxel, International Journal of Pharmaceutics, vol.344, issue.1-2, pp.143-149, 2007. ,
DOI : 10.1016/j.ijpharm.2007.06.014
URL : https://hal.archives-ouvertes.fr/inserm-00258366
A new generation of anticancer, drug-loaded, colloidal vectors reverses multidrug resistance in glioma and reduces tumor progression in rats, Molecular Cancer Therapeutics, vol.5, issue.7, pp.1710-1722, 2006. ,
DOI : 10.1158/1535-7163.MCT-06-0289
URL : https://hal.archives-ouvertes.fr/hal-00358958
Mitochondrial targeting by use of lipid nanocapsules loaded with SV30, an analogue of the small-molecule Bcl-2 inhibitor HA14-1, Journal of Controlled Release, vol.151, issue.1, pp.74-82, 2011. ,
DOI : 10.1016/j.jconrel.2010.11.032
URL : https://hal.archives-ouvertes.fr/hal-00842655
Lipid nanocarriers as drug delivery system for ibuprofen in pain treatment, International Journal of Pharmaceutics, vol.278, issue.2, pp.407-414, 2004. ,
DOI : 10.1016/j.ijpharm.2004.03.018
Tumor transfection after systemic injection of DNA lipid nanocapsules, Biomaterials, vol.32, issue.9, pp.2327-2333, 2011. ,
DOI : 10.1016/j.biomaterials.2010.11.063
Lipid nanocapsules loaded with rhenium-188 reduce tumor progression in a rat hepatocellular carcinoma model, PLoS ONE, vol.6, p.16926, 2011. ,
URL : https://hal.archives-ouvertes.fr/hal-00741696
Re-188-loaded lipid nanocapsules as a promising radiopharmaceutical carrier for internal radiotherapy of malignant gliomas, European Journal of Nuclear Medicine and Molecular Imaging, vol.35, pp.1838-1846, 2008. ,
URL : https://hal.archives-ouvertes.fr/inserm-00343438
Tumor eradication in rat glioma and bypass of immunosuppressive barriers using internal radiation with 188Re-lipid nanocapsules, Biomaterials, vol.32, pp.6781-6790, 2011. ,
Tc/ 188 Re-labelled lipid nanocapsules as promising radiotracers for imaging and therapy: Formulation and biodistribution, European Journal of Nuclear Medicine and Molecular Imaging, vol.33, pp.99-602, 2006. ,
Long-circulating DNA lipid nanocapsules as new vector for passive tumor targeting, Biomaterials, vol.31, issue.2, pp.31-321, 2010. ,
DOI : 10.1016/j.biomaterials.2009.09.044
URL : https://hal.archives-ouvertes.fr/inserm-00491402
Brain targeting using novel lipid nanovectors, Journal of Controlled Release, vol.126, issue.1, pp.44-49, 2008. ,
DOI : 10.1016/j.jconrel.2007.11.001
Development and characterization of immuno-nanocarriers targeting the cancer stem cell marker AC133, International Journal of Pharmaceutics, vol.423, issue.1, pp.93-101, 2012. ,
DOI : 10.1016/j.ijpharm.2011.06.001
Cancer nanotechnology: application of nanotechnology in cancer therapy, Drug Discovery Today, vol.15, issue.19-20, pp.842-850, 2010. ,
DOI : 10.1016/j.drudis.2010.08.006
Active targeting schemes for nanoparticle systems in cancer therapeutics, Advanced Drug Delivery Reviews, vol.60, issue.15, pp.1615-1626, 2008. ,
DOI : 10.1016/j.addr.2008.08.005
Integrins in cancer: biological implications and therapeutic opportunities, Nature Reviews Cancer, vol.13, issue.1, pp.9-22, 2010. ,
DOI : 10.1038/nrc2748
Phage Libraries Displaying Cyclic Peptides with Different Ring Sizes: Ligand Specificities of the RGD-Directed Integrins, Bio/Technology, vol.268, issue.3, pp.265-270, 1995. ,
DOI : 10.1016/0076-6879(82)82103-4
Cancer Treatment by Targeted Drug Delivery to Tumor Vasculature in a Mouse Model, Science, vol.279, issue.5349, pp.377-380, 1998. ,
DOI : 10.1126/science.279.5349.377
Tumor Regression by Targeted Gene Delivery to the Neovasculature, Science, vol.296, issue.5577, pp.2404-2407, 2002. ,
DOI : 10.1126/science.1070200
Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis, PNAS, vol.105, pp.9343-9348, 2008. ,
Tissue-penetrating delivery of compounds and nanoparticles into tumors, pp.16-510, 2009. ,
Intracellular delivery of doxorubicin with RGD-modified sterically stabilized liposomes for an improved antitumor efficacy: In vitro and in vivo, Journal of Pharmaceutical Sciences, vol.94, issue.8, pp.1782-1793, 2005. ,
DOI : 10.1002/jps.20397
Anti-tumor efficacy of tumor vasculature-targeted liposomal doxorubicin, Journal of Controlled Release, vol.91, issue.1-2, pp.115-122, 2003. ,
DOI : 10.1016/S0168-3659(03)00240-2
Targeting of tumor endothelium by RGD-grafted PLGA-nanoparticles loaded with paclitaxel, J Control Release, vol.140, pp.166-173, 2009. ,
Tumor targeting of functionalized lipid nanoparticles: Assessment by in vivo fluorescence imaging, European Journal of Pharmaceutics and Biopharmaceutics, vol.75, issue.2, pp.137-147, 2010. ,
DOI : 10.1016/j.ejpb.2010.02.007
Black, ? v ? 3 and ? v ? 5 integrin expression in glioma periphery, Neurosurgery, vol.49, pp.380-390, 2001. ,
Synthesis and Characterization of the ???Sulfur-Rich??? Bis(perthiobenzoato)(dithiobenzoato)technetium(III) Heterocomplex, Inorganic Chemistry, vol.41, issue.3, pp.41-598, 2002. ,
DOI : 10.1021/ic0107577
A brief survey of methods for preparing protein conjugates with dyes, haptens and crosslinking reagents, Bioconjugate Chemistry, vol.3, issue.1, pp.2-13, 1992. ,
DOI : 10.1021/bc00013a001
Post-insertion into Lipid NanoCapsules (LNCs): From experimental aspects to mechanisms, International Journal of Pharmaceutics, vol.396, issue.1-2, pp.204-209, 2010. ,
DOI : 10.1016/j.ijpharm.2010.06.019
Evaluation of pegylated lipid nanocapsules versus complement system activation and macrophage uptake, Journal of Biomedical Materials Research Part A, vol.21, issue.3, pp.78-620, 2006. ,
DOI : 10.1002/jbm.a.30711
Use of an aqueous soluble tetrazolium formazan assay for cell-growth assays in culture, Cancer Comm, vol.3, pp.207-212, 1991. ,
Preparation and functional evaluation of RGD-modified proteins as ? v ? 3 integrin directed therapeutics, Bioconjugate Chem, vol.13, pp.128-135, 2001. ,
Multivalent Effects of RGD Peptides Obtained by Nanoparticle Display, Journal of Medicinal Chemistry, vol.49, issue.20, pp.6087-6093, 2006. ,
DOI : 10.1021/jm060515m
?v-Integrin antagonist EMD 121974 induces apoptosis in brain tumor cells growing on vitronectin and tenascin, International Journal of Cancer, vol.46, issue.87, pp.690-697, 2002. ,
DOI : 10.1002/ijc.10265
Design of targeted lipid nanocapsules by conjugation of whole antibodies and antibody Fab??? fragments, Biomaterials, vol.28, issue.33, pp.4978-4990, 2007. ,
DOI : 10.1016/j.biomaterials.2007.05.014
Electrokinetic properties of noncharged lipid nanocapsules: Influence of the dipolar distribution at the interface, ELECTROPHORESIS, vol.15, issue.11, pp.2066-2075, 2005. ,
DOI : 10.1002/elps.200410145
Click Chemistry Functionalized Polymeric Nanoparticles Target Corneal Epithelial Cells through RGD-Cell Surface Receptors, Bioconjugate Chemistry, vol.20, issue.1, pp.87-94, 2009. ,
DOI : 10.1021/bc8003167
RGD-based strategies for selective delivery of therapeutics and imaging agents to the tumour vasculature, Drug Resistance Updates, vol.8, issue.6, pp.381-402, 2005. ,
DOI : 10.1016/j.drup.2005.10.002
The importance of endo-lysosomal escape with lipid nanocapsules for drug subcellular bioavailability, Biomaterials, vol.31, issue.29, pp.31-7542, 2010. ,
DOI : 10.1016/j.biomaterials.2010.06.024
Pharmacokinetics and distribution of a biodegradable drug-carrier, Int J Pharm, vol.15, pp.335-345, 1983. ,
Stealth nanoparticles: High density but sheddable PEG is a key for tumor targeting, Journal of Controlled Release, vol.145, issue.3, pp.178-181, 2010. ,
DOI : 10.1016/j.jconrel.2010.03.016
Targeting kidney mesangium by nanoparticles of defined size, Proceedings of the National Academy of Sciences, vol.108, issue.16, pp.6656-6661, 2011. ,
DOI : 10.1073/pnas.1103573108
Effect of particle size on the biodistribution of lipid nanocapsules: Comparison between nuclear and fluorescence imaging and counting, Int J Pharm, vol.453, pp.594-600, 2013. ,
URL : https://hal.archives-ouvertes.fr/inserm-00855672
Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS, Journal of Controlled Release, vol.74, issue.1-3, pp.47-61, 2001. ,
DOI : 10.1016/S0168-3659(01)00309-1
Arg-Gly-Asp (RGD) peptide conjugated poly(lactic acid)-poly(ethylene oxide) micelle for targeted drug delivery, Journal of Biomedical Materials Research Part A, vol.114, issue.1, Part 1, pp.85-797, 2008. ,
DOI : 10.1002/jbm.a.31615
??v??3 Integrin-targeting radionuclide therapy and imaging with monomeric RGD peptide, International Journal of Cancer, vol.59, issue.3, pp.709-715, 2008. ,
DOI : 10.1002/ijc.23575
? 3 and ? v ? ? integrins control glioma cell response to ionising radiation through ILK and RhoB, Int J Cancer, vol.123, pp.357-364, 2008. ,
Inhibition of ??v??3 Integrin Survival Signaling Enhances Antiangiogenic and Antitumor Effects of Radiotherapy, Clinical Cancer Research, vol.11, issue.17, pp.6270-6279, 2005. ,
DOI : 10.1158/1078-0432.CCR-04-1223