C. Amani-bosse, *. , and K. Brou, Achi Isidore Assi (ACONDA-MTCT-Plus)

C. Adults, *. §. Wejse, Z. Silva, *. , and J. Paulo, The Bissau HIV cohort study group: Amabelia Rodrigues (Bandim Health Project Ines Oliviera-Souto (Bandim Health Project, David da Silva (National HIV program Bissau), Candida Medina (Hospital National Simao Mendes Lars Østergaard Alex Laursen Jesper Eugen-Olsen (Dept. of Infectious Diseases

F. Dicko, *. , M. Sylla, A. Berthé, A. Hadizatou-coulibaly-traoré et al., Naïchata Traoré (CH Gabriel Toure) Nigeria: Adults, Festus Igbinoba (National Hospital Abuja) John Olasode (OATH, Ile-Ife)

A. Koko-lawson-evi, *. §. , Y. Atakouma, and E. Takassi, Améyo Djeha, Ayoko Ephoévi-gah, Sherifa El-Hadj Djibril, Pediatrics

J. Annie and . Sasco, Operational and Statistical Team: Dieudonné Amani

J. Gilbert, Eric Balestre Serge Bessekon, Franck Bohossou (Abidjan, Côte d'Ivoire), Sophie Karcher Jérôme Le Carrou Séverin Lenaud Célestin Nchot Bertine Siloué

P. Programme, Côte d'Ivoire. 2 Centre de Diagnostic et de Recherche sur le SIDA et les Maladies Opportunistes (CeDReS) Centre Hospitalier Universitaire (CHU) de Treichville, Abidjan, Côte d'Ivoire. 3 INSERM, Centre INSERM U897-Epidémiologie-Biostatistique, d'Ivoire. 6 Centre de Prise en charge de Recherche et de Formation (CePReF), Hôpital Yopougon Attié d'Ivoire. 7 Service de Maladies Infectieuses et Tropicales, pp.1471-2334607, 1954.

P. Braitstein, M. Brinkhof, F. Dabis, M. Schechter, A. Boulle et al., Mortality of HIV-1-infected patients in the first year of antiretroviral therapy: comparison between low-income and high-income countries, Lancet, issue.9513, pp.367817-824, 2006.

F. Diomande, E. Bissagnene, J. Nkengasong, C. Maurice, B. Monga et al., The most efficient use of resources to identify those in need of antiretroviral treatment in Africa, AIDS, vol.17, pp.17-87, 2003.
DOI : 10.1097/00002030-200317003-00012

P. De-beaudrap, J. Etard, A. Diouf, I. Ndiaye, G. Ndeye et al., Incidence and determinants of new AIDS-defining illnesses after HAART initiation in a Senegalese cohort, BMC Infectious Diseases, vol.362, issue.9377, p.179, 2010.
DOI : 10.1016/S0140-6736(03)13802-0

URL : https://hal.archives-ouvertes.fr/hal-00539296

N. Ford, K. Kranzer, K. Hilderbrand, G. Jouquet, E. Goemaere et al., Early initiation of antiretroviral therapy and associated reduction in mortality, morbidity and defaulting in a nurse-managed, community cohort in Lesotho, AIDS, vol.24, issue.17, pp.242645-2650
DOI : 10.1097/QAD.0b013e32833ec5b2

E. Losina, Y. Yazdanpanah, S. Deuffic-burban, B. Wang, L. Wolf et al., The independent effect of highly active antiretroviral therapy on severe opportunistic disease incidence and mortality in HIV-infected adults in Cote d'Ivoire, Antivir Ther, vol.12, issue.4, pp.543-551, 2007.
URL : https://hal.archives-ouvertes.fr/hal-00200067

R. Moh, C. Danel, E. Messou, T. Ouassa, D. Gabillard et al., Incidence and determinants of mortality and morbidity following early antiretroviral therapy initiation in HIV-infected adults in West Africa, AIDS, vol.21, issue.18, pp.2483-2491, 2007.
DOI : 10.1097/QAD.0b013e3282f09876

URL : https://hal.archives-ouvertes.fr/inserm-00173522

X. Anglaret, E. Messou, T. Ouassa, S. Toure, N. Dakoury-dogbo et al., Pattern of bacterial diseases in a cohort of HIV-1 infected adults receiving cotrimoxazole prophylaxis in Abidjan, C??te d'Ivoire, AIDS, vol.17, issue.4, pp.575-584, 2003.
DOI : 10.1097/00002030-200303070-00013

C. Holmes, E. Losina, R. Walensky, Y. Yazdanpanah, and K. Freedberg, Review of Human Immunodeficiency Virus Type 1???Related Opportunistic Infections in Sub???Saharan Africa, Clinical Infectious Diseases, vol.36, issue.5, pp.652-662, 2003.
DOI : 10.1086/367655

R. Colebunders and A. Latif, Natural history and clinical presentation of HIV-1 infection in adults, AIDS, vol.5, pp.103-112, 1991.

A. Grant, G. Djomand, and K. De-cock, Natural history and spectrum of disease in adults with HIV, AIDS in Africa. AIDS, vol.11, pp.43-54, 1997.

E. Molyneux and M. Weber, Applying the right standards to improve hospital performance in Africa, The Lancet, vol.364, issue.9445, pp.1560-1561, 2004.
DOI : 10.1016/S0140-6736(04)17326-1

X. Anglaret, A. Minga, D. Gabillard, T. Ouassa, E. Messou et al., AIDS and Non-AIDS Morbidity and Mortality Across the Spectrum of CD4 Cell Counts in HIV-Infected Adults Before Starting Antiretroviral Therapy in Cote d'Ivoire, Clinical Infectious Diseases, vol.54, issue.5, pp.714-737, 2012.
DOI : 10.1093/cid/cir898

H. World and . Organization, Antiretroviral Therapy for HIV Infection In Adults and Adolescents: Recommendations for a public health approach Available at, 2006.

C. Tonéatti, A. Bouxin-metro, and J. Dormont, Echelle ANRS de cotation de la gravité des événements indésirables graves chez l'adulte, Version n°6 du 9 septembre Paris: ANRS Available at: http://www.anrs.fr/ index, ANRS-GradeEI-V6-Fr-2003.pdf, 1537.

A. Beauliere, S. Toure, P. Alexandre, K. Kone, A. Pouhe et al., The Financial Burden of Morbidity in HIV-Infected Adults on Antiretroviral Therapy in C??te d'Ivoire, PLoS ONE, vol.373, issue.6, p.11213, 2010.
DOI : 10.1371/journal.pone.0011213.t003

X. Anglaret, N. Dakoury-dogbo, D. Bonard, S. Touré, P. Combe et al., Causes and empirical treatment of fever in HIV-infected adult outpatients, AIDS, issue.6, pp.16909-918, 2002.

D. Gabillard, C. Lewden, I. Ndoye, R. Moh, O. Segeral et al., Mortality, AIDS-Morbidity, and Loss to Follow-up by Current CD4 Cell Count Among HIV-1???Infected Adults Receiving Antiretroviral Therapy in Africa and Asia, JAIDS Journal of Acquired Immune Deficiency Syndromes, vol.62, issue.5, pp.555-561, 2013.
DOI : 10.1097/QAI.0b013e3182821821

C. Seyler, E. Messou, D. Gabillard, A. Inwoley, and A. Alioum, Anglaret X: Morbidity before and after HAART initiation in Sub-Saharan African HIV-infected adults: a recurrent event analysis, AIDS Res Hum Retroviruses, issue.11, pp.231338-1347, 2007.

J. Dave, E. Lambert, M. Badri, S. West, G. Maartens et al., Effect of Nonnucleoside Reverse Transcriptase Inhibitor???Based Antiretroviral Therapy on Dysglycemia and Insulin Sensitivity in South African HIV-Infected Patients, JAIDS Journal of Acquired Immune Deficiency Syndromes, vol.57, issue.4, pp.284-289, 2011.
DOI : 10.1097/QAI.0b013e318221863f

S. Sreenivasan and V. Dasegowda, Adverse effects after HAART Initiation in resource-limited settings: a prospective study from Mysore, India, The Journal of Infection in Developing Countries, vol.4, issue.11, pp.750-753, 2010.
DOI : 10.3855/jidc.934

J. Zhou, N. Paton, R. Ditangco, Y. Chen, A. Kamarulzaman et al., Experience with the use of a first-line regimen of stavudine, lamivudine and nevirapine in patients in the TREAT Asia HIV Observational Database, HIV Medicine, vol.87, issue.1, pp.8-16, 2007.
DOI : 10.1111/j.1468-1293.2005.00292.x

M. Bonnet, L. Pinoges, F. Varaine, B. Oberhauser, O. Brien et al., Tuberculosis after HAART initiation in HIV-positive patients from five countries with a high tuberculosis burden, AIDS, vol.20, issue.9, pp.1275-1279, 2006.
DOI : 10.1097/01.aids.0000232235.26630.ee

S. Lawn, M. Badri, and R. Wood, Tuberculosis among HIV-infected patients receiving HAART: long term incidence and risk factors in a South African cohort, AIDS, vol.19, issue.18, pp.2109-2116
DOI : 10.1097/01.aids.0000194808.20035.c1