The genetics of systemic sclerosis: an update, Clin Exp Rheumatol, vol.29, pp.75-86, 2011. ,
Criteria for the classification of early systemic sclerosis, J Rheumatol, vol.28, pp.1573-1576, 2001. ,
Attenuated liver fibrosis in the absence of B cells, Journal of Clinical Investigation, vol.115, issue.11, pp.3072-3082, 2005. ,
DOI : 10.1172/JCI24798DS1
CD19 regulates the development of bleomycin-induced pulmonary fibrosis in a mouse model, Arthritis & Rheumatism, vol.176, issue.11, pp.193574-3584, 2008. ,
DOI : 10.1002/art.23995
The role of B cells in systemic sclerosis, Biologics, vol.2, pp.389-395, 2008. ,
Systemic and cell type-specific gene expression patterns in scleroderma skin, Proceedings of the National Academy of Sciences, vol.100, issue.21, pp.12319-12324, 2003. ,
DOI : 10.1073/pnas.1635114100
Stimulation of Collagen and Glycosaminoglycan Production in Cultured Human Adult Dermal Fibroblasts by Recombinant Human Interleukin 6, Journal of Investigative Dermatology, vol.97, issue.4, pp.686-692, 1991. ,
DOI : 10.1111/1523-1747.ep12483971
Serum levels of interleukin-6 and interleukin-10 correlate with total skin thickness score in patients with systemic sclerosis, Journal of Dermatological Science, vol.27, issue.2, pp.140-146, 2001. ,
DOI : 10.1016/S0923-1811(01)00128-1
Role of Interleukin-6 in Bleomycin-Induced Lung Inflammatory Changes in Mice, American Journal of Respiratory Cell and Molecular Biology, vol.38, issue.5 ,
DOI : 10.1165/rcmb.2007-0299OC
Skin involvement in scleroderma--where histological and clinical scores meet, Rheumatology, vol.46, issue.5, pp.833-841, 2007. ,
DOI : 10.1093/rheumatology/kel451
URL : https://hal.archives-ouvertes.fr/inserm-00166113
Cracking the BAFF code, Nature Reviews Immunology, vol.173, issue.7, pp.491-502, 2009. ,
DOI : 10.1038/nri2572
The role of BAFF in immune function and implications for autoimmunity, Immunological Reviews, vol.167, issue.1, pp.43-54, 2005. ,
DOI : 10.1097/00002030-200309050-00018
Mice Transgenic for Baff Develop Lymphocytic Disorders along with Autoimmune Manifestations, The Journal of Experimental Medicine, vol.51, issue.11, pp.1697-1710, 1999. ,
DOI : 10.1038/32588
Elevated serum APRIL levels in patients with systemic sclerosis: distinct profiles of systemic sclerosis categorized by APRIL and BAFF, J Rheumatol, vol.34, pp.2056-2062, 2007. ,
Elevated serum BAFF levels in patients with systemic sclerosis: Enhanced BAFF signaling in systemic sclerosis B lymphocytes, Arthritis & Rheumatism, vol.48, issue.1, pp.192-201, 2006. ,
DOI : 10.1002/art.21526
B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating TandBcells, pp.807-817, 2004. ,
Elevated matrix metalloproteinase-9 in patients with systemic sclerosis, Arthritis Research & Therapy, vol.7, issue.1, pp.71-79, 2005. ,
DOI : 10.1186/ar1454
DNA topoisomerase I binding to fibroblasts induces monocyte adhesion and activation in the presence of anti???topoisomerase I autoantibodies from systemic sclerosis patients, Arthritis & Rheumatism, vol.86, issue.3, pp.963-973, 2006. ,
DOI : 10.1002/art.21646
Altered B lymphocyte function induces systemic autoimmunity in systemic sclerosis, Molecular Immunology, vol.41, issue.12, pp.1123-1133, 2004. ,
DOI : 10.1016/j.molimm.2004.06.025
Quantitative Genetic Variation in CD19 Expression Correlates with Autoimmunity, The Journal of Immunology, vol.165, issue.11, pp.6635-6643, 2000. ,
DOI : 10.4049/jimmunol.165.11.6635
Altered blood B lymphocyte homeostasis in systemic sclerosis: Expanded naive B cells and diminished but activated memory B cells, Arthritis & Rheumatism, vol.46, issue.6, pp.1918-1927, 2004. ,
DOI : 10.1002/art.20274
Systemic sclerosis Th2 cells inhibit collagen production by dermal fibroblasts via membrane-associated tumor necrosis factor ??, Arthritis & Rheumatism, vol.278, issue.Suppl 1, pp.2593-2604, 2003. ,
DOI : 10.1002/art.11129
Inhibition of type I collagen production by dermal fibroblasts upon contact with activated T cells: Different sensitivity to inhibition between systemic sclerosis and control fibroblasts, Arthritis & Rheumatism, vol.23, issue.11, pp.2039-2047, 1998. ,
DOI : 10.1002/1529-0131(199811)41:11<2039::AID-ART20>3.0.CO;2-1
ESTABLISHMENT AND CHARACTERIZATION OF A HUMAN B CELL LINE FROM THE LUNG TISSUE OF A PATIENT WITH SCLERODERMA; EXTRAORDINARY HIGH LEVEL OF IL-6 SECRETION BY STIMULATED FIBROBLASTS, Cytokine, vol.13, issue.4, pp.220-226, 2001. ,
DOI : 10.1006/cyto.2000.0822
Overview of pathogenesis of systemic sclerosis, Rheumatology, vol.48, issue.Supplement 3, pp.3-7, 2009. ,
DOI : 10.1093/rheumatology/ken481
Serum TIMP-1, TIMP-2, and MMP-1 in patients with systemic sclerosis, primary Raynaud's phenomenon, and in normal controls, Ann Rheum Dis, vol.60, pp.846-851, 2001. ,
Systemic sclerosis: a prototypic multisystem fibrotic disorder, Journal of Clinical Investigation, vol.117, issue.3, pp.557-567, 2007. ,
DOI : 10.1172/JCI31139
Myofibroblasts from scleroderma skin synthesize elevated levels of collagen and tissue inhibitor of metalloproteinase (TIMP-1) with two forms of TIMP-1 ,
Regulatory mechanisms for the production of BAFF and IL-6 are impaired in monocytes of patients of primary Sj??gren's syndrome, Arthritis Research & Therapy, vol.13, issue.5, p.170, 2011. ,
DOI : 10.1046/j.1365-2249.2002.01869.x
Adhesion and transcellular migration of neutrophils and B lymphocytes on fibroblasts, Experimental Cell Research, vol.315, issue.13, pp.2192-2206, 2009. ,
DOI : 10.1016/j.yexcr.2009.04.013
B cell depletion in diffuse progressive systemic sclerosis: safety, skin score modification and IL-6 modulation in an up to thirty-six months follow-up open-label trial, Arthritis Research & Therapy, vol.12, issue.2, p.54, 2010. ,
DOI : 10.1186/ar2965
Is There a Role for B-cell Depletion as Therapy for Scleroderma? A Case Report and Review of the Literature, Seminars in Arthritis and Rheumatism, vol.40, issue.2, pp.127-136, 2010. ,
DOI : 10.1016/j.semarthrit.2009.09.003
Effect of long-term treatment with rituximab on pulmonary function and skin fibrosis in patients with diffuse systemic sclerosis, Clin Exp Rheumatol, vol.30, pp.17-22, 2011. ,
B-Lymphocyte Depletion Reduces Skin Fibrosis and Autoimmunity in the Tight-Skin Mouse Model for Systemic Sclerosis, The American Journal of Pathology, vol.169, issue.3, pp.954-966, 2006. ,
DOI : 10.2353/ajpath.2006.060205
BAFF Antagonist Attenuates the Development of Skin Fibrosis in Tight-Skin Mice, Journal of Investigative Dermatology, vol.127, issue.12, pp.2772-2780, 2007. ,
DOI : 10.1038/sj.jid.5700919