P. Burger, F. Vogel, S. Green, and T. Strike, Glioblastoma multiforme and anaplastic astrocytoma pathologic criteria and prognostic implications, Cancer, vol.38, issue.5, pp.1106-1111, 1985.
DOI : 10.1002/1097-0142(19850901)56:5<1106::AID-CNCR2820560525>3.0.CO;2-2

C. Daumas-duport, M. Tucker, H. Kolles, P. Cervera, F. Beuvon et al., Part II: A new grading system based on morphological and imaging criteria, Journal of Neuro-Oncology, vol.34, issue.1, pp.61-78, 1997.
DOI : 10.1023/A:1005759220434

C. Daumas-duport, P. Varlet, M. Tucker, F. Beuvon, P. Cervera et al., Oligodendrogliomas. Part I: Patterns of growth, histological diagnosis, clinical and imaging correlations: a study of 153 cases, Journal of Neuro-Oncology, vol.34, issue.1, pp.37-59, 1997.
DOI : 10.1023/A:1005707203596

H. Takei, M. Bhattacharjee, A. Rivera, Y. Dancer, and S. Powell, New immunohistochemical markers in the evaluation of central nervous system tumors: a review of 7 selected adult and pediatric brain tumors, Arch Pathol Lab Med, vol.131, issue.2, pp.234-241, 2007.

J. Folkman, Role of angiogenesis in tumor growth and metastasis, Seminars in Oncology, vol.29, issue.6Q, pp.15-18, 2002.
DOI : 10.1053/sonc.2002.37263

M. Wintermark, M. Sesay, E. Barbier, K. Borbely, W. Dillon et al., Comparative overview of brain perfusion imaging techniques, Journal of Neuroradiology, vol.32, issue.5, pp.2032-2033, 2005.
DOI : 10.1016/S0150-9861(05)83159-1

URL : https://hal.archives-ouvertes.fr/inserm-00410400

S. Valable, B. Lemasson, R. Farion, M. Beaumont, C. Segebarth et al., study, NMR in Biomedicine, vol.90, issue.3, pp.1043-1056, 2008.
DOI : 10.1002/nbm.1278

URL : https://hal.archives-ouvertes.fr/inserm-00861168

J. Hasan, R. Byers, and G. Jayson, Intra-tumoural microvessel density in human solid tumours, British Journal of Cancer, vol.5, issue.10, pp.1566-1577, 2002.
DOI : 10.1038/sj.bjc.6600315

J. Jensen, H. Lu, and M. Inglese, Microvessel density estimation in the human brain by means of dynamic contrast-enhanced echo-planar imaging, Magnetic Resonance in Medicine, vol.208, issue.5, pp.1145-1150, 2006.
DOI : 10.1002/mrm.21052

J. Boxerman, L. Hamberg, B. Rosen, and R. Weisskoff, Mr contrast due to intravascular magnetic susceptibility perturbations, Magnetic Resonance in Medicine, vol.34, issue.4, pp.555-566, 1995.
DOI : 10.1002/mrm.1910340412

J. Dennie, J. Mandeville, J. Boxerman, S. Packard, B. Rosen et al., NMR imaging of changes in vascular morphology due to tumor angiogenesis, Magnetic Resonance in Medicine, vol.48, issue.6, pp.793-799, 1998.
DOI : 10.1002/mrm.1910400602

K. Schmainda, S. Rand, A. Joseph, R. Lund, B. Ward et al., Characterization of a first-pass gradient-echo spin-echo method to predict brain tumor grade and angiogenesis, AJNR Am J Neuroradiol, vol.25, issue.9, pp.1524-1532, 2004.

E. Wu, H. Tang, and J. Jensen, High-resolution MR imaging of mouse brain microvasculature using the relaxation rate shift indexQ, NMR in Biomedicine, vol.14, issue.7, pp.507-512, 2004.
DOI : 10.1002/nbm.921

J. Jensen and R. Chandra, MR imaging of microvasculature, Magnetic Resonance in Medicine, vol.29, issue.2, pp.224-230, 2000.
DOI : 10.1002/1522-2594(200008)44:2<224::AID-MRM9>3.0.CO;2-M

I. Tropres, S. Grimault, A. Vaeth, E. Grillon, C. Julien et al., Vessel size imaging, Magnetic Resonance in Medicine, vol.45, issue.3, pp.397-408, 2001.
DOI : 10.1002/1522-2594(200103)45:3<397::AID-MRM1052>3.3.CO;2-V

V. Kiselev, R. Strecker, S. Ziyeh, O. Speck, and J. Hennig, Vessel size imaging in humans, Magnetic Resonance in Medicine, vol.714, issue.3, pp.553-563, 2005.
DOI : 10.1002/mrm.20383

I. Tropres, L. Lamalle, M. Peoc-'h, R. Farion, Y. Usson et al., In vivo assessment of tumoral angiogenesis, Magnetic Resonance in Medicine, vol.88, issue.Suppl, pp.533-541, 2004.
DOI : 10.1002/mrm.20017

URL : https://hal.archives-ouvertes.fr/hal-00192515

K. Donahue, H. Krouwer, S. Rand, A. Pathak, C. Marszalkowski et al., Utility of simultaneously acquired gradient-echo and spin-echo cerebral blood volume and morphology maps in brain tumor patients, Magnetic Resonance in Medicine, vol.9, issue.6, pp.845-53, 2000.
DOI : 10.1002/1522-2594(200006)43:6<845::AID-MRM10>3.0.CO;2-J

C. Farrar, W. Kamoun, C. Ley, Y. Kim, S. Kwon et al., In vivo validation of MRI vessel caliber index measurement methods with intravital optical microscopy in a U87 mouse brain tumor model, Neuro-Oncology, vol.12, issue.4, pp.341-350, 2010.
DOI : 10.1093/neuonc/nop032

S. Valable, E. Barbier, M. Bernaudin, S. Roussel, C. Segebarth et al., In vivo MRI tracking of exogenous monocytes/macrophages targeting brain tumors in a rat model of glioma, NeuroImage, vol.40, issue.2, pp.973-983, 2008.
DOI : 10.1016/j.neuroimage.2008.01.005

URL : https://hal.archives-ouvertes.fr/inserm-00536177

M. Beaumont, B. Lemasson, R. Farion, C. Segebarth, C. Remy et al., Characterization of Tumor Angiogenesis in Rat Brain Using Iron-Based Vessel Size Index MRI in Combination with Gadolinium-Based Dynamic Contrast-Enhanced MRI, Journal of Cerebral Blood Flow & Metabolism, vol.10, issue.10, pp.1714-1726, 2009.
DOI : 10.1002/nbm.881

URL : https://hal.archives-ouvertes.fr/inserm-00410316

S. Meiboom and D. Gill, Modifed Spin Echo method of measuring nuclear relaxation times. The review of scientific instruments, pp.688-691, 1958.

A. Simonetti, V. Elezi, R. Farion, G. Malandain, C. Segebarth et al., A low temperature embedding and section registration strategy for 3D image reconstruction of the rat brain from autoradiographic sections, Journal of Neuroscience Methods, vol.158, issue.2, pp.242-250, 2006.
DOI : 10.1016/j.jneumeth.2006.06.004

URL : https://hal.archives-ouvertes.fr/inserm-00388981

A. Pathak, B. Ward, and K. Schmainda, A novel technique for modeling susceptibility-based contrast mechanisms for arbitrary microvascular geometries: The finite perturber method, NeuroImage, vol.40, issue.3, pp.1130-1143, 2008.
DOI : 10.1016/j.neuroimage.2008.01.022

T. Christen, G. Zaharchuk, N. Pannetier, R. Serduc, N. Joudiou et al., Quantitative MR estimates of blood oxygenation based on T2*: A numerical study of the impact of model assumptions, Magnetic Resonance in Medicine, vol.107, issue.5, 2011.
DOI : 10.1002/mrm.23094

URL : https://hal.archives-ouvertes.fr/inserm-00753894

N. Pannetier, B. Lemasson, T. Christen, M. Tachrount, I. Tropres et al., Vessel size index measurements in a rat model of glioma: comparison of the dynamic (Gd) and steady-state (iron-oxide) susceptibility contrast MRI approaches, NMR in Biomedicine, vol.32, issue.2, 2011.
DOI : 10.1002/nbm.1734

URL : https://hal.archives-ouvertes.fr/inserm-00658563

A. , M. Mri, M. Density, and V. Mri, and histological estimates (mVD histo , Density histo , VSI histo ) within the neocortex, the striatum, and the tumor of Wistar and Fischer rats. * p<0.05 between striatum and neocortex; $$ p<0.01 and $$$ p<0.001 between tumor and striatum; £ p<0.05, ££ p<0.01 and £££ p<0.001 between C6 and RG2 tumors, Table 1. ?? derived from change in iron plasma concentration for Wistar and Fisher rats, averaged across animals. MRI estimates Wistar Rats (C6 model) Fischer Rats (RG2 model) ??

$. , £. Vsi-mri-$-$, and £. Vsi, 6 $$ Density MRI (vessel. mm -2 ) 294 ± 48 240 ± 115 79, $$,££ Density histo (vessel.mm -2 )