Complete pathological regression of hepatocellular carcinoma with portal vein thrombosis treated with sorafenib.

Abstract : Sorafenib is a molecular-targeted therapy used in palliative treatment of advanced hepatocellular carcinoma (HCC) in Child-Pugh A patients. We describe the case of a patient who presented with a large HCC in the left liver associated with portal vein thrombosis (PVT). After 9 months of sorafenib treatment, reassessment showed that the tumors had decreased in size with recanalization of the portal vein. A lateral left hepatectomy was performed and pathology showed complete necrosis of the tumor. Sorafenib can downstage HCC in patients with cirrhosis allowing further surgical resection.
Type de document :
Article dans une revue
World Journal of Surgical Oncology, BioMed Central, 2013, 11 (1), pp.171. 〈10.1186/1477-7819-11-171〉
Liste complète des métadonnées

Littérature citée [17 références]  Voir  Masquer  Télécharger

http://www.hal.inserm.fr/inserm-00850497
Contributeur : Ed. Bmc <>
Soumis le : mardi 6 août 2013 - 21:09:07
Dernière modification le : mardi 5 juin 2018 - 10:14:43
Document(s) archivé(s) le : mercredi 5 avril 2017 - 19:44:34

Fichiers

Identifiants

Collections

Citation

Sabrina Kermiche-Rahali, Aude Di Fiore, Fanny Drieux, Frédéric Di Fiore, Arnaud François, et al.. Complete pathological regression of hepatocellular carcinoma with portal vein thrombosis treated with sorafenib.. World Journal of Surgical Oncology, BioMed Central, 2013, 11 (1), pp.171. 〈10.1186/1477-7819-11-171〉. 〈inserm-00850497〉

Partager

Métriques

Consultations de la notice

385

Téléchargements de fichiers

229