W. Haskell, I. Lee, R. Pate, K. Powell, S. Blair et al., Physical Activity and Public Health, Medicine & Science in Sports & Exercise, vol.39, issue.8, pp.1081-93, 2007.
DOI : 10.1249/mss.0b013e3180616b27

O. Donovan, G. Blazevich, A. Boreham, C. Cooper, A. Crank et al., The ABC of Physical Activity for Health: A consensus statement from the British Association of Sport and Exercise Sciences, Journal of Sports Sciences, vol.4, issue.7142, pp.573-91, 2010.
DOI : 10.1136/jech.2008.077305

M. Tremblay, R. Colley, T. Saunders, G. Healy, and N. Owen, Physiological and health implications of a sedentary lifestyle, Applied Physiology, Nutrition, and Metabolism, vol.35, issue.6, pp.725-765, 2010.
DOI : 10.1139/H10-079

N. Owen, A. Bauman, and W. Brown, Too much sitting: a novel and important predictor of chronic disease risk?, British Journal of Sports Medicine, vol.43, issue.2, pp.81-84, 2009.
DOI : 10.1136/bjsm.2008.055269

D. Dunstan, E. Barr, G. Healy, J. Salmon, J. Shaw et al., Television Viewing Time and Mortality: The Australian Diabetes, Obesity and Lifestyle Study (AusDiab), Circulation, vol.121, issue.3, pp.384-91, 2010.
DOI : 10.1161/CIRCULATIONAHA.109.894824

K. Wijndaele, S. Brage, H. Besson, K. Khaw, S. Sharp et al., Television Viewing and Incident Cardiovascular Disease: Prospective Associations and Mediation Analysis in the EPIC Norfolk Study, PLoS ONE, vol.27, issue.5, p.20058, 2011.
DOI : 10.1371/journal.pone.0020058.t005

S. Biddle, Sedentary Behavior, American Journal of Preventive Medicine, vol.33, issue.6, pp.502-506, 2007.
DOI : 10.1016/j.amepre.2007.08.002

B. Balkau, L. Mhamdi, J. Oppert, J. Nolan, A. Golay et al., Physical Activity and Insulin Sensitivity: The RISC Study, Diabetes, vol.57, issue.10, pp.2613-2621, 2008.
DOI : 10.2337/db07-1605
URL : https://hal.archives-ouvertes.fr/inserm-00292181

G. Healy, K. Wijndaele, D. Dunstan, J. Shaw, J. Salmon et al., Objectively Measured Sedentary Time, Physical Activity, and Metabolic Risk: The Australian Diabetes, Obesity and Lifestyle Study (AusDiab), Diabetes Care, vol.31, issue.2, pp.369-71, 2008.
DOI : 10.2337/dc07-1795

H. Helmerhorst, K. Wijndaele, S. Brage, N. Wareham, and U. Ekelund, Objectively Measured Sedentary Time May Predict Insulin Resistance Independent of Moderate- and Vigorous-Intensity Physical Activity, Diabetes, vol.58, issue.8, pp.1776-1785, 2009.
DOI : 10.2337/db08-1773

A. Bankoski, T. Harris, J. Mcclain, R. Brychta, P. Caserotti et al., Sedentary Activity Associated With Metabolic Syndrome Independent of Physical Activity, Diabetes Care, vol.34, issue.2, pp.497-503, 2011.
DOI : 10.2337/dc10-0987

R. Shephard, Limits to the measurement of habitual physical activity by questionnaires * Commentary, British Journal of Sports Medicine, vol.37, issue.>3
DOI : 10.1136/bjsm.37.3.197

M. Sjöström, P. Oja, M. Hagströmer, B. Smith, and A. Bauman, Health-enhancing physical activity across European Union countries: the Eurobarometer study, Journal of Public Health, vol.57, issue.5, pp.291-300, 2006.
DOI : 10.1007/s10389-006-0031-y

U. Ekelund, S. Brage, S. Griffin, N. Wareham, U. Proactive et al., Objectively Measured Moderate- and Vigorous-Intensity Physical Activity but Not Sedentary Time Predicts Insulin Resistance in High-Risk Individuals, Diabetes Care, vol.32, issue.6, pp.1081-1087, 2009.
DOI : 10.2337/dc08-1895

A. Cooper, S. Sebire, A. Montgomery, T. Peters, D. Sharp et al., Sedentary time, breaks in sedentary time and metabolic variables in people with newly diagnosed type 2 diabetes, Diabetologia, vol.100, issue.3, pp.589-99, 2012.
DOI : 10.1007/s00125-011-2408-x

R. Simmons, S. Griffin, R. Steele, N. Wareham, and U. Ekelund, Increasing overall physical activity and aerobic fitness is associated with improvements in metabolic risk: cohort analysis of the ProActive trial, Diabetologia, vol.29, issue.Suppl 2, pp.787-94, 2008.
DOI : 10.1007/s00125-008-0949-4

L. Byberg, B. Zethelius, P. Mckeigue, and H. Lithell, Changes in physical activity are associated with changes in metabolic cardiovascular risk factors, Diabetologia, vol.44, issue.12, pp.2134-2143, 2001.
DOI : 10.1007/s001250100022

D. Laaksonen, H. Lakka, J. Salonen, L. Niskanen, R. Rauramaa et al., Low Levels of Leisure-Time Physical Activity and Cardiorespiratory Fitness Predict Development of the Metabolic Syndrome, Diabetes Care, vol.25, issue.9, pp.1612-1620, 2002.
DOI : 10.2337/diacare.25.9.1612

M. Hernelahti, U. Kujala, and J. Kaprio, Stability and change of volume and intensity of physical activity as predictors of hypertension, Scandinavian Journal of Public Health, vol.32, issue.4, pp.303-312, 2004.
DOI : 10.1080/14034940410024167

B. Balkau, E. Vierron, M. Vernay, C. Born, D. Arondel et al., The impact of 3-year changes in lifestyle habits on metabolic syndrome parameters: the D, E.S.I.R study. Eur J Cardiovasc Prev Rehabil, vol.13, pp.334-374, 2006.
URL : https://hal.archives-ouvertes.fr/inserm-00126586

X. Yang, R. Telama, and M. Hirvensalo, The Longitudinal Effects of Physical Activity History on Metabolic Syndrome, Medicine & Science in Sports & Exercise, vol.40, issue.8, pp.1424-1455, 2008.
DOI : 10.1249/MSS.0b013e318172ced4

P. Cheriyath, Y. Duan, Z. Qian, L. Nambiar, and D. Liao, Obesity, physical activity and the development of metabolic syndrome: the atherosclerosis risk in communities study, European Journal of Cardiovascular Prevention & Rehabilitation
DOI : 10.1097/HJR.0b013e32833189b8

G. Healy, C. Matthews, D. Dunstan, E. Winkler, and N. Owen, Sedentary time and cardio-metabolic biomarkers in US adults: NHANES 2003???06, European Heart Journal, vol.32, issue.5, pp.590-597, 2011.
DOI : 10.1093/eurheartj/ehq451

S. Bertrais, J. Beyeme-ondoua, S. Czernichow, P. Galan, S. Hercberg et al., Sedentary Behaviors, Physical Activity, and Metabolic Syndrome in Middle-aged French Subjects, Obesity Research, vol.10, issue.Suppl 2, pp.936-980, 2005.
DOI : 10.1038/oby.2005.108

A. Thorp, G. Healy, and N. Owen, Deleterious Associations of Sitting Time and Television Viewing Time With Cardiometabolic Risk Biomarkers: Australian Diabetes, Obesity and Lifestyle (AusDiab) study 2004-2005, Diabetes Care, vol.33, issue.2, pp.327-361, 2004.
DOI : 10.2337/dc09-0493

E. Stamatakis and M. Hamer, The Extent to Which Adiposity Markers Explain the Association Between Sedentary Behavior and Cardiometabolic Risk Factors, Obesity, vol.88, issue.1, pp.229-261, 2012.
DOI : 10.1038/sj.ejcn.1602884

S. Hills, B. Balkau, S. Coppack, J. Dekker, A. Mari et al., The EGIR-RISC STUDY (The European group for the study of insulin resistance: relationship between insulin sensitivity and cardiovascular disease risk): I. Methodology and Objectives, Diabetologia, vol.47, issue.3, pp.566-70, 2004.
DOI : 10.1007/s00125-004-1335-5

D. Matthews, J. Hosker, A. Rudenski, B. Naylor, D. Treacher et al., Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man, Diabetologia, vol.92, issue.7, pp.412-421, 1985.
DOI : 10.1007/BF00280883

N. Wareham, D. Phillips, C. Byrne, and C. Hales, The 30 Minute Insulin Incremental Response in an Oral Glucose Tolerance Test as a Measure of Insulin Secretion, Diabetic Medicine, vol.37, issue.10, p.931, 1995.
DOI : 10.1111/j.1464-5491.1995.tb00399.x

P. Freedson, E. Melanson, and J. Sirard, Calibration of the Computer Science and Applications, Inc. accelerometer, Medicine & Science in Sports & Exercise, vol.30, issue.5, pp.777-81, 1998.
DOI : 10.1097/00005768-199805000-00021

U. Ekelund, S. Griffin, and N. Wareham, Physical Activity and Metabolic Risk in Individuals With a Family History of Type 2 Diabetes, Diabetes Care, vol.30, issue.2, pp.337-379, 2007.
DOI : 10.2337/dc06-1883

W. Willett and M. Stampfer, TOTAL ENERGY INTAKE: IMPLICATIONS FOR EPIDEMIOLOGIC ANALYSES, American Journal of Epidemiology, vol.124, issue.1
DOI : 10.1093/oxfordjournals.aje.a114366

G. Colditz, W. Willett, A. Rotnitzky, and J. Manson, Weight Gain as a Risk Factor for Clinical Diabetes Mellitus in Women, Annals of Internal Medicine, vol.122, issue.7, pp.481-487, 1995.
DOI : 10.7326/0003-4819-122-7-199504010-00001

R. Hanson, K. Narayan, D. Mccance, D. Pettitt, and L. Jacobsson, Rate of Weight Gain, Weight Fluctuation, and Incidence of NIDDM, Diabetes, vol.44, issue.3, pp.261-267, 1995.
DOI : 10.2337/diab.44.3.261

S. Wannamethee, A. Shaper, and M. Walker, Overweight and obesity and weight change in middle aged men: impact on cardiovascular disease and diabetes, Journal of Epidemiology & Community Health, vol.59, issue.2, pp.134-143, 2005.
DOI : 10.1136/jech.2003.015651

W. Willett, J. Manson, M. Stampfer, G. Colditz, B. Rosner et al., Weight, weight change, and coronary heart disease in women. Risk within the 'normal' weight range, JAMA: The Journal of the American Medical Association, vol.273, issue.6, pp.461-466, 1995.
DOI : 10.1001/jama.273.6.461

T. Zderic and M. Hamilton, Physical inactivity amplifies the sensitivity of skeletal muscle to the lipid-induced downregulation of lipoprotein lipase activity, Journal of Applied Physiology, vol.100, issue.1, p.25, 2012.
DOI : 10.1152/japplphysiol.00925.2005

A. Klip and M. Pâquet, Glucose Transport and Glucose Transporters in Muscle and Their Metabolic Regulation, Diabetes Care, vol.13, issue.3, pp.228-271, 1990.
DOI : 10.2337/diacare.13.3.228

A. Thorp, N. Owen, M. Neuhaus, and D. Dunstan, Sedentary Behaviors and Subsequent Health Outcomes in Adults, American Journal of Preventive Medicine, vol.41, issue.2, pp.207-222, 2011.
DOI : 10.1016/j.amepre.2011.05.004

K. Proper, A. Singh, W. Van-mechelen, and M. Chinapaw, Sedentary Behaviors and Health Outcomes Among Adults, American Journal of Preventive Medicine, vol.40, issue.2, pp.174-82, 2011.
DOI : 10.1016/j.amepre.2010.10.015

C. Laboratories, I. Reading-centres-lipids-dublin, . Gaffney, G. Nolan, . Boran-hormones-odense et al., The Netherlands: Denmark: Allan Flyvbjerg Ultrasound reading centre Pisa, Mathematical modelling and website management