Follow-up of coiled intracranial aneurysms: comparison of 3D time-of-flight and contrast-enhanced magnetic resonance angiography at 3T in a large, prospective series.

Abstract : OBJECTIVES: To compare 3D-TOF magnetic resonance angiography (MRA) and contrast-enhanced MRA (CE-MRA) sequences at 3T in the follow-up of coiled aneurysms with digital subtracted angiography (DSA) as the gold standard. METHODS: DSA, 3D-TOF and CE-MRA were performed in a prospective series of 126 aneurysms in 96 patients (57 female, 39 male; age: 25-75 years, mean: 51.3 ± 11.3 years). The quality of aneurysm occlusion was assessed independently and anonymously by a core laboratory. RESULTS: Using DSA (gold standard technique), total occlusion was depicted in 57 aneurysms (45.2%), neck remnant in 34 aneurysms (27.0%) and aneurysm remnant in 35 aneurysms (27.8%). Sensitivity, specificity, positive predictive value and negative predictive value were very similar with 3D-TOF and CE-MRA. Visibility of coils was much better with 3D-TOF (95.2%) than with CE-MRA (23.0%) (P < 0.001). Also, substantial artefacts were less frequent with 3D-TOF (4.0%) than with CE-MRA (11.9%; P = 0.012). CONCLUSIONS: In this large prospective series of patients with coiled aneurysms, at 3T 3D-TOF MRA was equivalent to CE-MRA for the evaluation of aneurysm occlusion, but coil visibility was superior at 3D-TOF. Thus the use of 3D-TOF at 3T is recommended for the follow-up of coiled intracranial aneurysms. KEY POINTS: * Different Magnetic Resonance (MR) imaging techniques are used to evaluate intracranial aneurysms. * At 3T MR, 3D-TOF and CE-MRA appear equivalent for evaluating coiled aneurysms.. * Coils are better visualised on 3D-TOF than on CE-MRA. * Combined analysis of 3D-TOF and CE-MRA does not seem helpful. * At 3T, 3D-TOF techniques are recommended for monitoring patients with coiled aneurysms.
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European Radiology, Springer Verlag, 2012, 22 (10), pp.2255-63. 〈10.1007/s00330-012-2466-6〉
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http://www.hal.inserm.fr/inserm-00845295
Contributeur : Jean-Yves Gauvrit <>
Soumis le : mardi 16 juillet 2013 - 17:26:12
Dernière modification le : lundi 25 juin 2018 - 16:02:02

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Laurent Pierot, Christophe Portefaix, Anne Boulin, Jean-Yves Gauvrit. Follow-up of coiled intracranial aneurysms: comparison of 3D time-of-flight and contrast-enhanced magnetic resonance angiography at 3T in a large, prospective series.. European Radiology, Springer Verlag, 2012, 22 (10), pp.2255-63. 〈10.1007/s00330-012-2466-6〉. 〈inserm-00845295〉

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