A. Hudspeth, How Hearing Happens, Neuron, vol.19, issue.5, pp.947-950, 1997.
DOI : 10.1016/S0896-6273(00)80385-2

M. Warchol, Sensory regeneration in the vertebrate inner ear: Differences at the levels of cells and species, Hearing Research, vol.273, issue.1-2, pp.72-79, 2011.
DOI : 10.1016/j.heares.2010.05.004

A. Zine and F. De-ribaupierre, Replacement of mammalian auditory hair cells, NeuroReport, vol.9, issue.2, pp.263-268, 1998.
DOI : 10.1097/00001756-199801260-00016

H. Staecker, . Van-de, and T. Water, Factors controlling hair-cell regeneration/repair in the inner ear, Current Opinion in Neurobiology, vol.8, issue.4, pp.480-487, 1998.
DOI : 10.1016/S0959-4388(98)80035-4

M. Lenoir and P. Vago, Does the organ of coati attempt to differentiate new hair cells after antibiotic intoxication in rat pups?, International Journal of Developmental Neuroscience, vol.15, issue.4-5, pp.487-495, 1997.
DOI : 10.1016/S0736-5748(96)00105-0

P. Chen, F. Zindy, C. Abdala, F. Liu, and X. Li, Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d, Nature Cell Biology, vol.126, issue.5, pp.422-426, 2003.
DOI : 10.1038/ncb976

C. Sage, M. Huang, K. Karimi, G. Gutierrez, and M. Vollrath, Proliferation of Functional Hair Cells in Vivo in the Absence of the Retinoblastoma Protein, Science, vol.307, issue.5712, pp.1114-1118, 2005.
DOI : 10.1126/science.1106642

J. Mantela, Z. Jiang, J. Ylikoski, B. Fritzsch, and E. Zacksenhaus, The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear, Development, vol.132, issue.10, pp.2377-2388, 2005.
DOI : 10.1242/dev.01834

H. Laine, A. Doetzlhofer, J. Mantela, J. Ylikoski, and M. Laiho, (Ink4d) and p21(Cip1) collaborate to maintain the postmitotic state of auditory hair cells, their codeletion leading to DNA damage and p53-mediated apoptosis, J. Neurosci, vol.27, pp.19-1434, 2007.

H. Laine, M. Sulg, A. Kirjavainen, and U. Pirvola, Cell cycle regulation in the inner ear sensory epithelia: Role of cyclin D1 and cyclin-dependent kinase inhibitors, Developmental Biology, vol.337, issue.1, pp.134-146, 2010.
DOI : 10.1016/j.ydbio.2009.10.027

E. Savary, J. Hugnot, Y. Chassigneux, C. Travo, and C. Duperray, Distinct Population of Hair Cell Progenitors Can Be Isolated from the Postnatal Mouse Cochlea Using Side Population Analysis, Stem Cells, vol.65, issue.2, pp.332-339, 2007.
DOI : 10.1634/stemcells.2006-0303

URL : https://hal.archives-ouvertes.fr/inserm-00137024

K. Oshima, C. Grimm, C. Corrales, P. Senn, M. Monedero et al., Differential Distribution of Stem Cells in the Auditory and Vestibular Organs of the Inner Ear, Journal of the Association for Research in Otolaryngology, vol.102, issue.1, pp.18-31, 2007.
DOI : 10.1007/s10162-006-0058-3

M. Diensthuber, K. Oshima, and S. Heller, Stem/Progenitor Cells Derived from the Cochlear Sensory Epithelium Give Rise to Spheres with Distinct Morphologies and Features, Journal of the Association for Research in Otolaryngology, vol.17, issue.2, pp.173-190, 2009.
DOI : 10.1007/s10162-009-0161-3

I. Smeti, E. Savary, V. Capelle, J. Hugnot, and A. Uziel, Expression of candidate markers for stem/progenitor cells in the inner ears of developing and adult GFAP and nestin promoter-GFP transgenic mice, Gene Expression Patterns, vol.11, issue.1-2, pp.22-32, 2011.
DOI : 10.1016/j.gep.2010.08.008

V. Trevino, F. Falciani, and H. Barrera-saldañ-a, DNA microarrays: a powerful genomic tool for biomedical and clinical research, Mol. Med, vol.13, pp.527-541, 2007.

R. Hawkins, S. Bashiardes, C. Helms, L. Hu, and N. Saccone, Gene expression differences in quiescent versus regenerating hair cells of avian sensory epithelia: implications for human hearing and balance disorders, Human Molecular Genetics, vol.12, issue.11, pp.1261-1272, 2003.
DOI : 10.1093/hmg/ddg150

R. Hawkins, S. Bashiardes, K. Powder, S. Sajan, and V. Bhonagiri, Large Scale Gene Expression Profiles of Regenerating Inner Ear Sensory Epithelia, PLoS ONE, vol.(in press), issue.6, p.525, 2007.
DOI : 10.1371/journal.pone.0000525.s022

C. Paxton, S. Bleyl, S. Chapman, and G. Schoenwolf, Identification of differentially expressed genes in early inner ear development, Gene Expression Patterns, vol.10, issue.1, pp.31-43, 2010.
DOI : 10.1016/j.gep.2009.11.002

B. Mcdermott, . Jr, J. Baucom, and A. Hudspeth, Analysis and functional evaluation of the hair-cell transcriptome, Proceedings of the National Academy of Sciences, vol.104, issue.28, pp.11820-11825, 2007.
DOI : 10.1073/pnas.0704476104

J. Schuck, H. Sun, W. Penberthy, N. Cooper, and X. Li, Transcriptomic analysis of the zebrafish inner ear points to growth hormone mediated regeneration following acoustic trauma, BMC Neuroscience, vol.12, issue.1, p.88, 2011.
DOI : 10.1002/jnr.21533

J. Lin, M. Ozeki, E. Javel, Z. Zhao, and W. Pan, Identification of gene expression profiles in rat ears with cDNA microarrays, Hearing Research, vol.175, issue.1-2, pp.2-13, 2003.
DOI : 10.1016/S0378-5955(02)00704-9

Y. Cho, T. Gong, T. Stöver, M. Lomax, and R. Altschuler, Gene Expression Profiles of the Rat Cochlea, Cochlear Nucleus, and Inferior Colliculus, JARO - Journal of the Association for Research in Otolaryngology, vol.3, issue.1, 2002.
DOI : 10.1007/s101620010042

K. Morris, E. Snir, C. Pompeia, I. Koroleva, and B. Kachar, Differential Expression of Genes within the Cochlea as Defined by a Custom Mouse Inner Ear Microarray, Journal of the Association for Research in Otolaryngology, vol.99, issue.Database issue, pp.75-89, 2005.
DOI : 10.1007/s10162-004-5046-x

S. Sajan, M. Warchol, and M. Lovett, Toward a Systems Biology of Mouse Inner Ear Organogenesis: Gene Expression Pathways, Patterns and Network Analysis, Genetics, vol.177, issue.1, pp.631-653, 2007.
DOI : 10.1534/genetics.107.078584

T. Sato, K. Doi, H. Hibino, and T. Kubo, Analysis of gene expression profiles along the tonotopic map of mouse cochlea by cDNA microarrays, Acta Oto-Laryngologica, vol.223, issue.sup562, pp.12-17, 2009.
DOI : 10.1007/BF00464301

D. Meghan and N. Konrad, Mapping quantitative trait loci for hearing loss in Black Swiss mice, Hear. Res, vol.212, pp.128-139, 2006.

V. Tusher, R. Tibshirani, and G. Chu, Significance analysis of microarrays applied to the ionizing radiation response, Proceedings of the National Academy of Sciences, vol.98, issue.9, pp.5116-5121, 2001.
DOI : 10.1073/pnas.091062498

M. Eisen, P. Spellman, P. Brown, and D. Botstein, Cluster analysis and display of genome-wide expression patterns, Proceedings of the National Academy of Sciences, vol.95, issue.25, pp.14863-14868, 1998.
DOI : 10.1073/pnas.95.25.14863

R. Sokal and C. Michener, A Statistical Method for Evaluating Systematic Relationships, Univ Kans Sci Bull, vol.38, pp.1409-1438, 1958.

K. Livak and T. Schmittgen, Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2???????CT Method, Methods, vol.25, issue.4, pp.402-408, 2001.
DOI : 10.1006/meth.2001.1262

K. Pfannkuche, H. Summer, O. Li, J. Hescheler, and P. Dröge, The High Mobility Group Protein HMGA2: A Co-Regulator of Chromatin Structure and Pluripotency in Stem Cells?, Stem Cell Reviews and Reports, vol.19, issue.3, pp.224-230, 2009.
DOI : 10.1007/s12015-009-9078-9

P. Tsonis, M. Call, M. Grogg, M. Sartor, and R. Taylor, MicroRNAs and regeneration: Let-7 members as potential regulators of dedifferentiation in lens and inner ear hair cell regeneration of the adult newt, Biochemical and Biophysical Research Communications, vol.362, issue.4, pp.940-945, 2007.
DOI : 10.1016/j.bbrc.2007.08.077

E. Slattery, J. Speck, and M. Warchol, Epigenetic Influences on Sensory Regeneration: Histone Deacetylases Regulate Supporting Cell Proliferation in the Avian Utricle, Journal of the Association for Research in Otolaryngology, vol.265, issue.3, pp.341-353, 2009.
DOI : 10.1007/s10162-009-0166-y

T. Kaur, D. Mukherjea, K. Sheehan, S. Jajoo, and L. Rybak, Short interfering RNA against STAT1 attenuates cisplatin-induced ototoxicity in the rat by suppressing inflammation, Cell Death and Disease, vol.11, issue.7, p.180, 2011.
DOI : 10.1038/cddis.2011.63

K. Ogita, T. Matsunobu, and J. Schacht, Acoustic trauma enhances DNA binding of transcription factor AP-1 in the guinea pig inner ear, NeuroReport, vol.11, issue.4, pp.859-862, 2000.
DOI : 10.1097/00001756-200003200-00040

R. Nagashima, C. Sugiyama, M. Yoneyama, and K. Ogita, Transcriptional Factors in the Cochlea Within the Inner Ear, Journal of Pharmacological Sciences, vol.99, issue.4, pp.301-306, 2005.
DOI : 10.1254/jphs.CPJ05004X

B. Fritzsch, I. Jahan, N. Pan, J. Kersigo, and J. Duncan, Dissecting the molecular basis of organ of Corti development: Where are we now?, Hearing Research, vol.276, issue.1-2, pp.16-26, 2011.
DOI : 10.1016/j.heares.2011.01.007

A. Groves and D. Fekete, Shaping sound in space: the regulation of inner ear patterning, Development, vol.139, issue.2, pp.245-257, 2012.
DOI : 10.1242/dev.067074

L. Krebs, M. Deftos, M. Bevan, and T. Gridley, The Nrarp Gene Encodes an Ankyrin-Repeat Protein That Is Transcriptionally Regulated by the Notch Signaling Pathway, Developmental Biology, vol.238, issue.1, pp.110-119, 2001.
DOI : 10.1006/dbio.2001.0408

P. Pirot, L. Van-grunsven, J. Marine, D. Huylebroeck, and E. Bellefroid, Direct regulation of the Nrarp gene promoter by the Notch signaling pathway, Biochemical and Biophysical Research Communications, vol.322, issue.2, pp.526-534, 2004.
DOI : 10.1016/j.bbrc.2004.07.157

N. Daudet and J. Lewis, Two contrasting roles for Notch activity in chick inner ear development: specification of prosensory patches and lateral inhibition of hair-cell differentiation, Development, vol.132, issue.3, pp.541-551, 2005.
DOI : 10.1242/dev.01589

M. Merika and D. Thanos, Enhanceosomes, Current Opinion in Genetics & Development, vol.11, issue.2, pp.205-208, 2001.
DOI : 10.1016/S0959-437X(00)00180-5

U. Hirning-folz, M. Wilda, V. Rippe, J. Bullerdiek, and H. Hameister, The expression pattern of the Hmgic gene during development, Genes, Chromosomes and Cancer, vol.23, issue.4, pp.350-357, 1998.
DOI : 10.1002/(SICI)1098-2264(199812)23:4<350::AID-GCC10>3.3.CO;2-5

C. Mayr, M. Hemann, and D. Bartel, Disrupting the Pairing Between let-7 and Hmga2 Enhances Oncogenic Transformation, Science, vol.315, issue.5818, pp.1576-1579, 2007.
DOI : 10.1126/science.1137999

I. Büssing, F. Slack, and H. Grosshans, let-7 microRNAs in development, stem cells and cancer, Trends in Molecular Medicine, vol.14, issue.9, pp.400-409, 2008.
DOI : 10.1016/j.molmed.2008.07.001

R. Ramachandran, B. Fausett, and D. Goldman, Ascl1a regulates M??ller glia dedifferentiation and retinal regeneration through a Lin-28-dependent, let-7 microRNA signalling pathway, Nature Cell Biology, vol.28, issue.11, pp.1101-1107, 2010.
DOI : 10.1038/ncb2115

O. Li, J. Li, and P. Dröge, DNA architectural factor and proto-oncogene HMGA2 regulates key developmental genes in pluripotent human embryonic stem cells, FEBS Letters, vol.73, issue.18, pp.3533-3537, 2007.
DOI : 10.1016/j.febslet.2007.06.072

J. Nishino, I. Kim, K. Chada, and S. Morrison, Hmga2 Promotes Neural Stem Cell Self-Renewal in Young but Not Old Mice by Reducing p16Ink4a and p19Arf Expression, Cell, vol.135, issue.2, pp.227-239, 2008.
DOI : 10.1016/j.cell.2008.09.017

F. Chen, J. Schacht, and S. Sha, Aminoglycoside-induced histone deacetylation and hair cell death in the mouse cochlea, Journal of Neurochemistry, vol.8, issue.5, pp.1226-1236, 2009.
DOI : 10.1111/j.1471-4159.2009.05871.x

K. Horner, R. Guieu, J. Magnan, A. Chays, and Y. Cazals, Prolactinoma in Some M??ni??re's Patients ??? Is Stress Involved?, Neuropsychopharmacology, vol.26, issue.1, pp.135-138, 2002.
DOI : 10.1016/S0893-133X(01)00356-6

K. Falkenius-schmidt, S. Rydmarker, and K. Horner, Hyperprolactinemia in some M??ni??re patients even in the absence of incapacitating vertigo, Hearing Research, vol.203, issue.1-2, pp.154-158, 2005.
DOI : 10.1016/j.heares.2004.11.015

K. Horner, Y. Cazals, R. Guieu, M. Lenoir, and N. Sauze, Experimental estrogen-induced hyperprolactinemia results in bone-related hearing loss in the guinea pig, AJP: Endocrinology and Metabolism, vol.293, issue.5, pp.1224-1232, 2007.
DOI : 10.1152/ajpendo.00279.2007

K. Price, X. Zhu, P. Guimaraes, O. Vasilyeva, and R. Frisina, Hormone replacement therapy diminishes hearing in peri-menopausal mice, Hearing Research, vol.252, issue.1-2, pp.29-36, 2009.
DOI : 10.1016/j.heares.2009.02.010

H. Sun, C. Lin, and M. Smith, Growth Hormone Promotes Hair Cell Regeneration in the Zebrafish (Danio rerio) Inner Ear following Acoustic Trauma, PLoS ONE, vol.207, issue.11, p.28372, 2011.
DOI : 10.1371/journal.pone.0028372.g006

B. Kopecky and B. Fritzsch, Regeneration of Hair Cells: Making Sense of All the Noise, Pharmaceuticals, vol.4, issue.12, pp.848-879, 2011.
DOI : 10.3390/ph4060848

Y. Cho, T. Gong, A. Kanicki, R. Altschuler, and M. Lomax, Noise overstimulation induces immediate early genes in the rat cochlea, Molecular Brain Research, vol.130, issue.1-2, pp.134-148, 2004.
DOI : 10.1016/j.molbrainres.2004.07.017

P. Forlano, M. Marchaterre, D. Deitcher, and A. Bass, Distribution of androgen receptor mRNA expression in vocal, auditory, and neuroendocrine circuits in a teleost fish, The Journal of Comparative Neurology, vol.69, issue.4, pp.493-512, 2010.
DOI : 10.1002/cne.22233

E. Reiter, P. Bonnet, B. Sente, D. Dombrowicz, and J. De-leval, Growth hormone and prolactin stimulate androgen receptor, insulin-like growth factor-I (IGF-I) and IGF-I receptor levels in the prostate of immature rats, Molecular and Cellular Endocrinology, vol.88, issue.1-3, pp.77-87, 1992.
DOI : 10.1016/0303-7207(92)90011-T

B. Belandia, S. Powell, J. García-pedrero, M. Walker, and C. Bevan, Hey1, a Mediator of Notch Signaling, Is an Androgen Receptor Corepressor, Molecular and Cellular Biology, vol.25, issue.4, pp.1425-1436, 2005.
DOI : 10.1128/MCB.25.4.1425-1436.2005

P. Nantermet, J. Xu, Y. Yu, P. Hodor, and D. Holder, Identification of Genetic Pathways Activated by the Androgen Receptor during the Induction of Proliferation in the Ventral Prostate Gland, Journal of Biological Chemistry, vol.279, issue.2, pp.1310-1322, 2004.
DOI : 10.1074/jbc.M310206200