Regulating the regulator: post-translational modification of RAS, Nature Reviews Molecular Cell Biology, vol.109, issue.1, pp.39-51, 2012. ,
DOI : 10.1038/nrm3255
in pyramidal neurons results in reorganization of mouse neocortical afferents, Journal of Neurobiology, vol.98, issue.3, pp.263-274, 2004. ,
DOI : 10.1002/neu.20019
Sites of Phosphorylation by Protein Kinase A in CDC25Mm/GRF1, a Guanine Nucleotide Exchange Factor for Ras, Journal of Biological Chemistry, vol.276, issue.3, pp.1742-1749, 2001. ,
DOI : 10.1074/jbc.M005770200
URL : https://hal.archives-ouvertes.fr/hal-00771803
Glial Cell Line-Derived Neurotrophic Factor Reverses Alcohol-Induced Allostasis of the Mesolimbic Dopaminergic System: Implications for Alcohol Reward and Seeking, Journal of Neuroscience, vol.31, issue.27, pp.9885-9894, 2011. ,
DOI : 10.1523/JNEUROSCI.1750-11.2011
GEFs and GAPs: Critical Elements in the Control of Small G Proteins, Cell, vol.129, issue.5, pp.865-877, 2007. ,
DOI : 10.1016/j.cell.2007.05.018
A role for the Ras signalling pathway in synaptic transmission and long-term memory, Nature, vol.390, pp.281-286, 1997. ,
Excessive alcohol consumption is blocked by glial cell line???derived neurotrophic factor, Alcohol, vol.43, issue.1, pp.35-43, 2009. ,
DOI : 10.1016/j.alcohol.2008.12.001
RAS Interaction with PI3K: More Than Just Another Effector Pathway, Genes & Cancer, vol.2, issue.3, pp.261-274, 2011. ,
DOI : 10.1177/1947601911408079
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128635
Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1, Nature, vol.415, issue.6871, pp.526-530, 2002. ,
DOI : 10.1038/nature711
Ras history, Small GTPases, vol.14, issue.1, pp.2-27, 2010. ,
DOI : 10.4161/sgtp.1.1.12178
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109476
Binge Drinking Upregulates Accumbens mGluR5-Homer2-PI3K Signaling: Functional Implications for Alcoholism, Journal of Neuroscience, vol.29, issue.27, pp.8655-8668, 2009. ,
DOI : 10.1523/JNEUROSCI.5900-08.2009
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761716
Nucleotide Sequence Variation within the PI3K p85 Alpha Gene Associates with Alcohol Risk Drinking Behaviour in Adolescents, PLoS ONE, vol.1, issue.1, p.1769, 2008. ,
DOI : 10.1371/journal.pone.0001769.t005
Ras-Guanine Nucleotide-Releasing Factor 1 (Ras-GRF1) Controls Activation of Extracellular Signal-Regulated Kinase (ERK) Signaling in the Striatum and Long-Term Behavioral Responses to Cocaine, Biological Psychiatry, vol.66, issue.8, pp.758-768, 2009. ,
DOI : 10.1016/j.biopsych.2009.03.014
Regulation of Neuronal Function by Ras-GRF Exchange Factors, Genes & Cancer, vol.2, issue.3, pp.306-319, 2011. ,
DOI : 10.1177/1947601911408077
The RasGrf family of mammalian guanine nucleotide exchange factors, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, vol.1815, issue.2, pp.170-188, 2011. ,
DOI : 10.1016/j.bbcan.2010.11.001
Constitutive Ras activity induces hippocampal hypertrophy and remodeling of pyramidal neurons in synRas mice, Journal of Neuroscience Research, vol.179, issue.Suppl, pp.630-641, 2004. ,
DOI : 10.1002/jnr.20194
The role of mesolimbic dopamine in the development and maintenance of ethanol reinforcement, Pharmacology & Therapeutics, vol.103, issue.2, pp.121-146, 2004. ,
DOI : 10.1016/j.pharmthera.2004.06.002
mTOR signaling: At the crossroads of plasticity, memory and disease, Trends in Neurosciences, vol.33, issue.2, pp.67-75, 2010. ,
DOI : 10.1016/j.tins.2009.11.003
NEURAL MECHANISMS OF ADDICTION: The Role of Reward-Related Learning and Memory, Annual Review of Neuroscience, vol.29, issue.1, pp.565-598, 2006. ,
DOI : 10.1146/annurev.neuro.29.051605.113009
Constitutively active H-ras accelerates multiple forms of plasticity in developing visual cortex, Proceedings of the National Academy of Sciences, vol.107, issue.44, pp.19026-19031, 2010. ,
DOI : 10.1073/pnas.1013866107
The role of synaptic GTPase-activating protein in neuronal development and synaptic plasticity, J Neurosci, vol.23, pp.1119-1124, 2003. ,
Alcoholism: Allostasis and Beyond, Alcoholism: Clinical & Experimental Research, vol.16, issue.2, pp.232-243, 2003. ,
DOI : 10.1007/s002130100773
Neurocircuitry of Addiction, Neuropsychopharmacology, vol.16, issue.1, pp.217-238, 2010. ,
DOI : 10.1016/S0006-3223(00)01070-2
Modulation of Presynaptic Plasticity and Learning by the H-ras/Extracellular Signal-Regulated Kinase/Synapsin I Signaling Pathway, Journal of Neuroscience, vol.25, issue.42, pp.9721-9734, 2005. ,
DOI : 10.1523/JNEUROSCI.2836-05.2005
Downregulation of mu opioid receptor by RNA interference in the ventral tegmental area reduces ethanol consumption in mice, Genes, Brain and Behavior, vol.32, issue.8, pp.728-735, 2007. ,
DOI : 10.1111/j.1601-183X.2007.00303.x
Differential expression of the ras gene family in mice., Molecular and Cellular Biology, vol.7, issue.4, pp.1535-1540, 1987. ,
DOI : 10.1128/MCB.7.4.1535
Recent advances in the neurobiology of alcoholism: the role of adenosine, Pharmacology & Therapeutics, vol.101, issue.1, pp.39-46, 2004. ,
DOI : 10.1016/j.pharmthera.2003.10.002
Regulation of long-term potentiation by H-Ras through NMDA receptor phosphorylation [In Process Citation], J Neurosci, vol.20, pp.2504-2511, 2000. ,
Phosphorylation of Serine 916 of Ras-GRF1 Contributes to the Activation of Exchange Factor Activity by Muscarinic Receptors, Journal of Biological Chemistry, vol.274, issue.52, pp.37379-37384, 1999. ,
DOI : 10.1074/jbc.274.52.37379
RACK1 and Brain-Derived Neurotrophic Factor: A Homeostatic Pathway That Regulates Alcohol Addiction, Journal of Neuroscience, vol.24, issue.46, pp.10542-10552, 2004. ,
DOI : 10.1523/JNEUROSCI.3714-04.2004
Complexes of Ras.GTP with Raf-1 and mitogen-activated protein kinase kinase, Science, vol.260, issue.5114, pp.1658-1661, 1993. ,
DOI : 10.1126/science.8503013
N-Ras or K-Ras inhibition increases the number and enhances the function of Foxp3 regulatory T cells, European Journal of Immunology, vol.66, issue.6, pp.1493-1502, 2008. ,
DOI : 10.1002/eji.200838292
Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis, Proceedings of the National Academy of Sciences, vol.103, issue.16, pp.6368-6373, 2006. ,
DOI : 10.1073/pnas.0510188103
Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders, Proceedings of the National Academy of Sciences, vol.107, issue.46, pp.20093-20098, 2010. ,
DOI : 10.1073/pnas.1005554107
URL : https://hal.archives-ouvertes.fr/inserm-00800434
AKT Signaling Pathway in the Nucleus Accumbens Mediates Excessive Alcohol Drinking Behaviors, Biological Psychiatry, vol.70, issue.6, pp.575-582, 2011. ,
DOI : 10.1016/j.biopsych.2011.03.019
Is the Ras-MAPK signalling pathway necessary for long-term memory formation?, Trends in Neurosciences, vol.22, issue.1, pp.38-44, 1999. ,
DOI : 10.1016/S0166-2236(98)01306-X
Transcriptional and epigenetic mechanisms of addiction, Nature Reviews Neuroscience, vol.59, issue.11, pp.623-637, 2011. ,
DOI : 10.1038/nrn3111
Signaling Pathways Mediating Alcohol Effects, Curr Top Behav Neurosci, 2011. ,
DOI : 10.1007/978-3-642-28720-6_161
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684072
A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference, Nature Genetics, vol.33, issue.3, pp.401-406, 2003. ,
DOI : 10.1038/ng1117
The addicted synapse: mechanisms of synaptic and structural plasticity in nucleus accumbens, Trends in Neurosciences, vol.33, issue.6, pp.267-276, 2010. ,
DOI : 10.1016/j.tins.2010.02.002
Farnesyltransferase and geranylgeranyltransferase I inhibitors and cancer therapy: Lessons from mechanism and bench-to-bedside translational studies, Oncogene, vol.19, issue.56, pp.6584-6593, 2000. ,
DOI : 10.1038/sj.onc.1204146
Intermittent Access to 20% Ethanol Induces High Ethanol Consumption in Long-Evans and Wistar Rats, Alcoholism: Clinical and Experimental Research, vol.70, issue.Suppl. 1, pp.1816-1823, 2008. ,
DOI : 10.1111/j.1530-0277.2008.00753.x
The neurobiology of binge-like ethanol drinking: Evidence from rodent models, Physiology & Behavior, vol.106, issue.3, pp.325-331, 2012. ,
DOI : 10.1016/j.physbeh.2011.12.026
Small GTP-Binding Proteins, Physiol Rev, vol.81, pp.153-208, 2001. ,
DOI : 10.1016/S0074-7696(08)61861-6
H-Ras Modulates N-Methyl-D-aspartate Receptor Function via Inhibition of Src Tyrosine Kinase Activity, Journal of Biological Chemistry, vol.278, issue.26, pp.23823-23829, 2003. ,
DOI : 10.1074/jbc.M302389200
Neuropharmacology of alcohol addiction, British Journal of Pharmacology, vol.62, issue.Suppl 2, pp.299-315, 2008. ,
DOI : 10.1038/bjp.2008.30
Spatially restricting gene expression by local translation at synapses, Trends in Neurosciences, vol.33, issue.4, pp.173-182, 2010. ,
DOI : 10.1016/j.tins.2010.01.005
Phosphorylation of the Ras-GRF1 Exchange Factor at Ser916/898 Reveals Activation of Ras Signaling in the Cerebral Cortex, Journal of Biological Chemistry, vol.278, issue.15, pp.13278-13285, 2003. ,
DOI : 10.1074/jbc.M209805200
Small G Protein Signaling in Neuronal Plasticity and Memory Formation: The Specific Role of Ras Family Proteins, Neuron, vol.68, issue.3, pp.340-361, 2010. ,
DOI : 10.1016/j.neuron.2010.09.013
Protein Prenylation: Molecular Mechanisms and Functional Consequences, Annual Review of Biochemistry, vol.65, issue.1, pp.241-269, 1996. ,
DOI : 10.1146/annurev.bi.65.070196.001325